Source

load("cardiovascular_wgs.RData")
#library(devtools)
#devtools::install_github("YiqianZhang1004/BetaTREND")
library(BetaTREND)
library(phyloseq)
library(vegan)
## Warning: package 'vegan' was built under R version 4.2.3
## Loading required package: permute
## Loading required package: lattice
## Warning: package 'lattice' was built under R version 4.2.3
## This is vegan 2.6-6.1

Age

age <- as.numeric(sample_data(ps)[["Age..years."]])
keep <- !is.na(age)   
ps_filt <- prune_samples(keep, ps)  
age_filt <- as.numeric(sample_data(ps_filt)[["Age..years."]] )
dist_bray_filt <- phyloseq::distance(ps_filt, method = "bray")
res <- BetaTREND::gradient_projection(dist_bray_filt, age_filt)
## Warning: package 'viridis' was built under R version 4.2.3
## Loading required package: viridisLite

res
## $projection_scores
##   [1]  1.711151663  0.208592185 -2.488257724 -1.744215497 -0.359973439
##   [6]  1.169932649  2.947980076 -2.582385469 -0.179483263 -0.648243989
##  [11] -1.244679894 -1.569861842  0.153562588 -0.245494582 -1.495829118
##  [16]  2.643984666  1.113166580 -1.505720918  1.408177365 -1.601396058
##  [21] -1.632628006 -1.076457978  2.110962407  0.324694227 -1.285137703
##  [26] -1.721298242 -0.456232368 -3.338327968  1.230136848 -0.294191751
##  [31] -0.893758177 -1.283279602 -1.576194472  2.441243371  0.145985289
##  [36] -0.475773550 -2.398624149  0.234220699 -0.044305607 -1.446959964
##  [41]  0.756570124 -0.576814935 -2.151036730  0.473570809  0.732095010
##  [46] -0.711679684 -1.957657739 -2.908122268  0.700174862 -0.785667403
##  [51]  0.095315721  0.851885467 -1.004410510  1.125999967 -0.594568422
##  [56] -2.706085610  0.322203493  1.647190020  2.827452720 -1.002668722
##  [61]  1.391762352 -1.371793272 -1.308481657 -1.330910866 -0.806533374
##  [66]  1.519766410  0.070473674  0.215451392 -0.558734260 -1.009144013
##  [71]  0.988785552  2.707994132  2.076501980 -1.899451654  1.270127729
##  [76] -1.511803441  1.212992053  2.863810370  3.371125330 -2.322355948
##  [81] -1.300402851  2.747714460 -2.139245734 -1.195624829 -0.427439417
##  [86]  1.228620825  3.576473900 -0.456480006 -3.564880405 -1.147443889
##  [91]  0.829104463  1.743071400 -1.918948779 -0.387016828 -0.871477538
##  [96]  1.925261450  2.360585636 -0.071476138 -0.050856623  1.220414220
## [101] -0.500352284  0.802064584 -1.689006861 -1.851870376  2.607629751
## [106] -2.716237323  0.926875270  2.805225725 -2.119842167 -0.865905807
## [111]  0.344382569 -3.026497415 -0.450609822 -2.465243597 -1.490705409
## [116]  0.681390680 -1.546967403  1.384128648  0.754694686 -3.082632459
## [121] -0.978767549  2.606411451  1.153609902  0.231056358 -3.199665501
## [126] -0.905394166 -0.732753767 -0.679606958 -0.568404817 -1.836459086
## [131] -0.186803474  2.107395794 -0.052366659  1.165019104 -1.194852168
## [136] -2.360029702  1.025396080 -2.852041572  0.273952009  0.187427877
## [141] -0.066868556 -0.531333003 -0.189536246 -1.142685688 -1.304269761
## [146]  1.427895405  0.636259292  0.112448200 -0.885363019 -1.686556827
## [151]  0.023789471  0.090601640 -2.494841320 -0.850126962  1.938874379
## [156] -2.559102957  1.811303611 -2.241553903 -2.316526933  1.721450249
## [161] -0.944745318 -0.686017960 -1.562279037 -0.719722192 -0.530500675
## [166] -0.939091502  2.739182022  1.271162008 -1.067155104  2.309299720
## [171] -0.300852214 -0.478961848  0.635513451  1.059364917 -0.410490015
## [176]  0.628813317 -1.249320295  0.376156998  2.683644032 -1.246118360
## [181] -1.486077235  1.097364445  0.831268559  0.326490982  0.821824776
## [186]  1.513475297 -0.590284349 -0.127602088 -1.440525022 -1.474483197
## [191] -0.091747176 -0.990522099 -0.176857948  2.903892439  0.128860556
## [196]  0.948502104  1.506325710 -4.244086170  0.509268780 -1.013219008
## [201] -1.240855139 -0.695810085 -3.587457699 -0.313585564 -0.795101131
## [206]  0.573031733 -0.790434356 -0.595353766 -0.276070610 -0.365496750
## [211] -1.904137914 -0.473881225  0.287124217 -0.715746320 -2.764352286
## [216]  1.289435005  1.557727012  0.329913925  0.194842053  0.116985337
## [221] -1.091896632  0.134381268  0.401283948 -2.102918603 -1.513310001
## [226]  3.599298433  0.828566752 -0.423659963 -1.121305687 -1.694155381
## [231]  1.666851502 -0.120800000 -0.006832118  0.849262418 -0.975430678
## [236] -0.700901995  2.370535010  0.827258932 -2.177366587  1.687239929
## [241]  1.390924705  0.356058962 -0.179503295  0.097350613  2.871999506
## [246] -1.533693044 -0.527091923  2.857463909 -1.557959229 -1.100839078
## [251]  2.138171006 -1.351592977  0.688105706  1.426421357 -0.264384675
## [256] -0.705780726 -0.124216204  0.798736652 -2.961159116  0.431635310
## [261] -2.979996961  2.618098010 -1.755340761  1.199958487 -1.068847305
## [266] -2.087385513 -1.395267149 -1.907983658  0.464688824 -1.586412193
## [271]  1.922185833  0.200631129 -0.285615798  0.101263817  4.164292312
## [276] -1.340350186  0.358786693 -0.318071564  0.760230995  3.113965215
## [281]  0.701650398 -1.315218673  0.545699467 -1.138582695  1.815980306
## [286] -2.658655638  3.149867224 -0.908073237 -1.007982781  3.151675632
## [291]  3.243030415  0.689490139  1.136767602 -2.372796958  3.067211270
## [296] -0.094175912  1.306196457  0.299712766 -0.869293065  0.645801289
## [301] -0.191018926 -2.071414202  1.561656634  0.228772358  1.740226441
## [306] -1.257994192  1.542170940 -3.451817179 -1.987558996  1.287430897
## [311]  2.498899478 -1.238208092  0.259908107 -0.743644069  0.891100004
## [316] -0.782545826 -0.030574858 -0.983754493  2.858759042 -0.936559079
## [321] -0.571525937  1.769072580  1.758864095 -0.199777259 -1.501020414
## [326]  1.671434549 -1.835982958 -1.070788938 -2.276921725  1.265684457
## [331] -0.084208158  0.649442921  3.384613587 -1.006394197 -1.790287363
## [336] -2.623915016  2.778631296  0.627639737  0.878948568 -0.880567496
## [341] -2.558265766 -2.069444111  0.623997907 -0.530521898 -0.630594009
## [346]  0.141695525 -0.826809688 -0.062608534  0.021286654  0.665872435
## [351]  0.543623779  1.392344895 -0.118699605  0.547145864  1.042465980
## [356] -1.026145575  1.796207519  3.321027463 -2.448693305  0.270661051
## [361]  4.112620088 -2.113659083  3.271365715 -1.088511875 -2.739095436
## [366]  0.289831677  0.378787487 -0.346867081  0.042606935 -0.986424840
## [371] -1.128672505 -3.157812521 -1.746999211 -1.180779337 -3.451042487
## [376] -0.674218542  2.069774553 -2.292082566  0.218560690 -1.808920634
## [381]  1.252504048  4.076216482  2.269769165 -0.064944229  1.157883355
## [386] -1.113972842 -1.021243416  3.493863440 -0.532941102 -1.113884181
## [391]  0.884462756 -1.151915427 -1.205628651 -0.700699839 -1.567939070
## [396] -3.630338685 -1.414968675  0.961687671  2.586324138 -1.476486294
## [401]  1.145599543  2.312906335  0.692113393  0.823163689  0.006082512
## [406]  1.271609475  0.708229787 -2.257624637 -2.498482162 -0.526626918
## [411] -0.421252575  1.638058043 -1.264027917 -1.145319550 -0.033768352
## [416]  0.580018128 -4.017248397  0.112699383  0.621860407 -0.345220652
## [421] -3.768143301  1.430940201 -2.507581178  0.645839522  2.030520193
## [426] -0.695453245 -0.964995267 -1.146057758  0.399662975 -0.959243969
## [431]  0.562771866 -1.706236867 -1.568321646 -3.193740064  0.414261986
## [436]  2.235564720 -0.412567472 -1.594422460 -0.135513549 -1.815633049
## [441]  0.418261517 -0.181635389  0.437185191 -2.989989390 -0.443171594
## [446]  1.884868995  1.318543851 -1.796525934 -0.179949098 -0.843885957
## [451] -1.938659865 -1.385036353  1.155348954 -0.481200315  1.127493530
## [456]  0.393593942 -0.298084377 -3.898760493  1.179500659 -2.969872688
## [461] -1.148995147  0.817514061  0.931736920 -1.059046080 -1.924049985
## [466] -2.706570096 -2.106082631 -0.859262172 -3.305878726  0.451846425
## [471] -0.461768296 -1.147421767 -0.026500395  0.259747267  1.546949914
## [476] -0.955506749 -1.287400362  0.589021690 -1.949141382  1.105195201
## [481] -0.741061357 -0.763491105  1.899871438  3.742781671  2.592463441
## [486] -0.634847133 -1.402093691 -0.923156240 -0.846107033  0.064990924
## [491]  0.753147389 -0.525844703 -1.795476287 -2.675709037 -3.205309132
## [496]  1.591073108 -2.783546998 -0.919981482  1.042884293 -0.445839562
## [501] -1.734952301  2.202448624  0.952814660 -2.285555574  0.902523696
## [506]  0.467472273 -0.909967277 -0.844162023  2.711853392 -1.929480945
## [511] -1.437783851  0.442045965  0.679245064 -1.092100470 -0.277218146
## [516]  0.101102309 -1.195889045  1.629270538  1.475450490 -0.099597810
## [521] -0.935623602 -3.949405406  3.672813215  0.428805618  1.495555916
## [526] -0.379288749  2.101021044 -0.209639582 -1.216794111 -1.959128069
## [531] -1.335189481 -1.085985377  0.543938102 -0.940176212 -3.624938206
## [536]  0.820700113  0.785999193  0.879375801 -0.789004378 -0.345227741
## [541]  1.504299972  0.552985046 -0.820972195 -1.311355654  2.907731768
## [546]  1.018142353 -2.922186746  0.436351051  2.341855649  1.193238414
## [551]  3.099543696 -3.135439858  1.189545267  1.785524751 -1.940171313
## [556]  1.668435019 -0.414487688 -0.911200581  2.664814534 -2.854200460
## [561]  2.111018703 -1.392513763 -2.123593437 -0.750057147  1.066425664
## [566] -2.056007110 -0.718707822  1.274151176 -0.644022818 -0.158611561
## [571] -0.412118598  0.517827445 -1.679397588 -0.914462621 -1.477692295
## [576] -2.713364284 -0.618652347 -3.313801594  3.626945926  2.286162790
## [581] -1.748179554  0.948813722 -1.444596441 -0.068916758  2.534719330
## [586]  1.275478300 -3.557080744  3.282891958 -1.080562729  0.670989662
## [591]  3.167307017 -0.534607895  2.084843315 -1.054780328  2.686046649
## [596]  0.445706922  1.581007385 -2.884145349 -1.384253798  1.469884093
## [601] -0.232412960 -0.666706871 -1.683925566 -0.593234555  1.979986188
## [606]  0.092606860 -0.629017521 -1.075289903 -2.563163927 -0.227836686
## [611]  2.239114147  2.698679297 -1.341328388  0.574276993  3.657254590
## [616] -3.803106770 -0.276511490 -0.071122659 -3.029272319 -0.523268788
## [621]  0.096141325 -0.786324834  0.388845025 -1.976208129 -2.434944611
## [626] -2.970566417 -0.461848760  0.577270812 -0.569011328  3.828368136
## [631] -0.081613174  1.015174692 -1.473526793 -3.374017895  0.004332140
## [636] -0.830781142 -1.597136553  1.922744101  0.646519547  0.287987306
## [641]  1.178891313 -1.427328038 -0.617168077  0.059362710 -3.302394350
## [646]  0.103253059 -2.200056214  2.235635381 -0.554450755 -0.394813033
## [651]  3.070284509 -0.607113376 -1.820183270  1.189710941 -1.546951095
## [656]  0.729804049 -0.606595917 -0.067683543 -1.900226204  2.829415198
## [661]  0.065732072  1.443461156  0.332718132  3.069683956 -0.001156077
## [666]  1.680168804  0.806026890  2.298038941 -0.984854872 -0.446151109
## [671]  3.708659987 -0.092841682  0.293064348  2.865640996 -1.391685092
## [676] -0.651301794  2.173874953 -1.600834191  0.653921185  2.600928540
## [681] -1.835807896  0.142542282 -0.228795111  2.697095368 -1.156195070
## [686] -0.603729343  1.312491630  1.439113757 -1.980239449  3.459964094
## [691] -0.150337261  0.689324907  3.361621691  2.789958096  1.773484284
## [696] -1.100193114 -0.647565570 -3.140071548 -1.346500355 -1.715553454
## [701]  2.567328149  1.481543879  2.669834584  3.675383850  3.924205267
## [706]  1.909403895  0.436304247  1.568669349  1.115643150 -0.051382979
## [711]  3.246874040  0.023311405 -0.153370186  0.364114621  2.001161443
## [716]  2.194062325 -1.319589443 -0.651580615  1.832229521  1.032282096
## [721] -1.051747593 -3.613120784  3.616759448 -1.425555092 -0.804593121
## [726] -0.480139688  2.220112403 -1.405765448  3.145811300  1.096471509
## [731]  1.037302305 -0.137607574  0.192533666 -1.722583227  2.252781519
## [736]  2.661135769 -1.686475566  0.432989762 -1.416982482  2.409072012
## [741] -0.089648630 -1.568296307  1.517567731  0.680912001  0.303591958
## [746] -0.975531964 -1.840626893  0.520750945  1.766591150  0.833943513
## [751] -2.791365350  0.368791351 -0.024579545  3.734335817  0.245972945
## [756]  3.080813849  1.913121003  2.527331762  2.615603989 -0.683678129
## [761] -1.814765054  1.754197832  2.513213287  2.702797900 -0.975574003
## [766] -0.384186292  1.319966498 -0.802812442 -0.592882433 -0.277170527
## [771] -1.739934437 -3.159588308 -1.336418086 -2.569766643 -1.392663109
## [776]  2.668562585  2.294223061  1.392933237  4.179593251 -1.865001310
## [781]  3.143424001  0.808610447  2.352498369 -2.228076769  1.001501372
## [786]  2.715876138  2.567782985 -1.494443363  0.690501798  0.667419233
## [791] -0.015964983  2.446191126  2.243930662 -2.386352042 -2.023985378
## [796] -0.860920571 -0.590551838  1.289323393  2.258696260 -1.134200650
## [801]  2.459705779  3.195339969  0.450015356  2.836037023 -1.533829128
## [806] -1.123788623 -0.778022091 -1.470987108 -0.282502129  3.278283502
## [811] -3.284485431  0.951805167  1.870692728 -1.641943752  3.504218938
## [816] -0.208166105 -0.122212787 -0.386183573 -0.023021405 -1.443843812
## [821]  2.599327832  0.325050831 -0.783223925  2.664149108 -2.406973102
## [826] -3.116036878  1.330375838 -1.272013767  0.701625837  2.919235580
## [831]  2.276962698  1.355839818  3.433248576 -0.595767428 -0.535423730
## [836]  1.065241506  3.334744854  2.428652608 -1.103409358  0.059423431
## [841]  2.891867359  1.953878500  1.865716079 -0.916262309  0.208394900
## [846] -0.893893628  2.807604263 -2.099562168  3.723002572 -1.622747354
## [851]  1.340036326 -0.362825225  1.945236166 -0.043751150 -2.424435835
## [856] -1.497538793  3.223642229 -0.206670887  1.459217591 -0.864508705
## [861]  0.519167924 -0.814192255 -0.447413774
## 
## $gradient_direction
##            [,1]
## [1,]  0.6481881
## [2,]  2.6755250
## [3,] -5.7136806
## [4,] 12.4784083
## [5,] -5.5558332
## 
## $PCoA_coordinates
##                     [,1]          [,2]          [,3]          [,4]
## x10MCx1146  2.335390e-01  2.644326e-01 -0.0822706072  0.0408846837
## x10MCx1176 -1.768681e-01  2.987848e-02  0.1060308824  0.0686075317
## x10MCx1206 -7.083261e-02  8.777525e-02  0.1138081742 -0.0992059427
## x10MCx1350 -3.856703e-02  1.253411e-01  0.0718077182 -0.1195155724
## x10MCx1390 -3.252480e-01 -4.297364e-02 -0.1433108662 -0.1061252523
## x10MCx1529  1.205542e-02  6.980762e-02  0.1099600052  0.1341169625
## x10MCx1563  2.186745e-01  1.890438e-01 -0.4588786598  0.0408021495
## x10MCx1585 -3.101093e-03  1.640561e-01  0.0654003836 -0.1554293030
## x10MCx1667 -4.944310e-02  5.204622e-02  0.1173251707  0.0529983476
## x10MCx1745 -9.830579e-02  1.237167e-01  0.1105785147 -0.0489720941
## x10MCx1810  1.082598e-01  2.745902e-01 -0.1000183770 -0.1789135063
## x10MCx1936 -2.574027e-01  3.654140e-02  0.0573918290 -0.1042051216
## x10MCx2044 -1.845132e-01  3.060710e-02  0.0496111339  0.0497640875
## x10MCx2066 -2.429192e-01 -5.948643e-02 -0.0386166213 -0.0066669622
## x10MCx2097  1.248955e-01  2.046235e-01 -0.0645797198 -0.1427806820
## x10MCx2262  2.537398e-01  2.190862e-01 -0.3981054694  0.0250515339
## x10MCx2294 -3.359678e-01 -1.178577e-01 -0.2290949130 -0.0078929033
## x10MCx2392 -1.561560e-01 -5.240730e-03  0.1139150569 -0.0249100264
## x10MCx2550  2.497117e-01  2.828354e-01 -0.3620967068 -0.0598370259
## x10MCx2839 -4.528937e-02  5.200984e-02  0.0719740402 -0.0048420942
## x10MCx2862  1.044082e-01 -3.661534e-01  0.0394939115  0.0301879014
## x10MCx3024  3.475454e-01 -1.774419e-01  0.0033193775 -0.1081220333
## x10MCx3098 -1.807346e-01 -1.652284e-01 -0.1213278444  0.2255532010
## x10MCx3111 -3.361013e-01 -1.201732e-01 -0.2612794521 -0.0934637336
## x10MCx3144 -1.546459e-01  6.607078e-03  0.0357787041 -0.0786725029
## x10MCx3329 -1.616610e-01  5.985403e-03 -0.0668879827 -0.1056018470
## x10MCx3358 -2.677478e-01 -6.958190e-02 -0.2289295115 -0.1320866583
## x10MCx3391 -8.405116e-02  1.747163e-01 -0.0336835068 -0.2805137282
## x10MCx3419  3.366615e-01 -1.441314e-01 -0.0051373593  0.0400488720
## x13MCx1129  3.532906e-01 -2.044196e-01  0.0509262281 -0.0200506663
## x13MCx1340 -9.879508e-02  7.177521e-02  0.1561371105  0.0210282974
## x13MCx1381 -1.452872e-01 -1.262781e-02  0.0864406580  0.0046158978
## x13MCx1398 -2.013192e-01 -2.868926e-02 -0.1247916440 -0.1448301550
## x13MCx1416  6.449300e-02 -1.431816e-03  0.0659450268  0.1642680652
## x13MCx1553 -1.588760e-01 -1.211423e-02  0.0873355475  0.0628200263
## x13MCx1818 -1.780746e-01 -8.442508e-02 -0.0874775680  0.0150425696
## x13MCx2054 -5.369736e-02  1.216741e-01  0.0416865549 -0.1511645372
## x13MCx2232 -2.916106e-01 -1.314503e-01 -0.1618247319 -0.0047743799
## x13MCx2282 -4.836886e-02  4.583214e-02  0.1437905500  0.1171967757
## x13MCx2401 -2.363853e-01  1.478532e-02  0.0789886195 -0.0687989819
## x13MCx2621  2.618315e-01 -1.830786e-01  0.0911008944  0.1028409864
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## x13MCx2963 -2.658136e-01 -1.157234e-01 -0.1957328806 -0.0030286361
## x13MCx2965  4.048156e-01 -1.189496e-01 -0.0129981175 -0.0117464235
## x13MCx3205  3.680953e-01 -3.595059e-01 -0.0530555922 -0.0347046642
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## x14MCx1118 -2.417481e-01  2.118821e-02  0.0386945163  0.0318152747
## x14MCx1158 -1.303295e-03  1.848993e-01  0.1109120048 -0.0575463428
## x14MCx1190  6.599611e-02  1.757364e-01  0.1176500730  0.0344094679
## x14MCx1209  6.221523e-02  1.056338e-01  0.1103636788  0.0705442741
## x14MCx1227  5.077924e-02  1.931079e-01  0.0963558492 -0.0435581407
## x14MCx1302  1.022431e-01  2.214997e-01  0.0584741682  0.0594296758
## x14MCx1313 -7.772519e-02  4.485475e-02  0.1357498645  0.0493875998
## x14MCx1363  3.889447e-01 -3.883136e-01 -0.0523715930 -0.1521349479
## x14MCx1397  1.544531e-01  1.755704e-01  0.0407972068  0.0154127852
## x14MCx1399  3.080968e-01  1.334976e-01 -0.1004722080  0.0170176849
## x14MCx1485  2.358211e-01  2.147023e-01 -0.4694167746  0.0301284986
## x14MCx1540 -1.360039e-01  9.768168e-02  0.1357445754 -0.0235729583
## x14MCx1551  3.070904e-01  1.365487e-03  0.0396496059  0.0552908859
## x14MCx1578 -1.936296e-01  2.470289e-02  0.0645001824 -0.0671286786
## x14MCx1583  1.834883e-02  1.920829e-01  0.0867853831 -0.0645400543
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## x14MCx1616  3.866017e-02  1.798571e-01  0.0949759097 -0.0458814895
## x14MCx1621  2.111624e-01  1.757522e-01  0.0152091009  0.0274469438
## x14MCx1706  1.576544e-01  3.024162e-01 -0.0662952234 -0.0808423284
## x14MCx1724 -1.305108e-02  1.740793e-01  0.1144110464  0.0287860944
## x14MCx1739  5.867838e-02  2.116472e-01  0.0601579911 -0.0512435043
## x14MCx1747 -1.832012e-01  1.385033e-02  0.0490463882 -0.0069397007
## x14MCx1768  2.207047e-01  1.790594e-01  0.0527463169  0.0349974767
## x14MCx1775  3.305308e-01  2.338870e-01 -0.2737853751  0.0216908558
## x14MCx1798  3.208722e-01  1.508678e-01 -0.1907719124 -0.0133681000
## x14MCx1861  2.328488e-02 -3.692001e-01  0.0486473232  0.0298302414
## x14MCx1910  1.333824e-01  1.975135e-01  0.0411060373  0.0643604278
## x14MCx1914  1.075791e-02  1.737098e-01  0.0593582500 -0.0972494785
## x14MCx1916 -1.773031e-01  7.627151e-02 -0.0058193678  0.0069766581
## x14MCx1929  3.103596e-01  4.370903e-02 -0.0552151337  0.1061688648
## x14MCx1940  2.519911e-01  1.905198e-01 -0.4475415995  0.0666425450
## x14MCx1943 -1.056730e-01 -3.782230e-01 -0.0616117941 -0.0963544403
## x14MCx1953  1.005720e-01  2.186607e-01  0.1105557173 -0.0708142094
## x14MCx1965  2.179802e-01  2.106241e-01 -0.0366756422  0.1245507196
## x14MCx1997 -1.978050e-01  9.723683e-02  0.0378392430 -0.1735366046
## x14MCx2055 -2.089741e-01 -1.908044e-02  0.0642734892 -0.0006369022
## x14MCx2088  7.620957e-02  2.311716e-01  0.0574436075 -0.0433779015
## x14MCx2162  2.399440e-01  7.594473e-02  0.0817506230  0.0715698131
## x14MCx2193  3.833958e-01 -5.125361e-02 -0.1494223632  0.1138238759
## x14MCx2220  4.359088e-02  1.941070e-01  0.1107985699 -0.0312980736
## x14MCx2237  6.667905e-02 -2.944524e-01  0.0834786717 -0.1462946345
## x14MCx2263  3.616772e-01 -1.508711e-01  0.0432994724 -0.0931674147
## x14MCx2269  7.132052e-02  2.568519e-02  0.0805281194  0.0972897673
## x14MCx2325  9.477051e-02  1.554507e-01  0.1157904367  0.1510655285
## x14MCx2355  2.832209e-01 -1.755217e-01  0.1010980753 -0.0850598750
## x14MCx2365  1.048333e-01  1.941285e-01  0.1350144068  0.0225338188
## x14MCx2381  1.907766e-02  1.802892e-01  0.1168329142 -0.0313300526
## x14MCx2393  1.776502e-01  1.450813e-01  0.0006448620  0.1178923049
## x14MCx2420  1.259074e-01  2.451722e-02  0.1075030942  0.2114571894
## x14MCx2429 -2.074051e-02  5.180096e-02  0.1560927152  0.0977051705
## x14MCx2437 -2.089899e-01 -1.126489e-02  0.0812806149  0.0564000707
## x14MCx2453  1.498439e-01 -8.101324e-02  0.1054732550  0.1200124135
## x14MCx2468 -2.971139e-02  1.290484e-01  0.1271348319  0.0013253858
## x14MCx2479  1.743930e-01  9.006352e-02  0.1252985633  0.0776641739
## x14MCx2494 -7.185638e-02  1.286105e-01  0.1331775331 -0.0882707668
## x14MCx2498 -2.276328e-01 -3.637513e-02  0.0105667503 -0.0653840121
## x14MCx2510  1.584695e-01  1.681556e-01 -0.0664111973  0.1444802337
## x14MCx2563 -9.577349e-02  1.213395e-01  0.0855233948 -0.1595190137
## x14MCx2587  2.196945e-01  1.277620e-02  0.0913970257  0.0713841437
## x14MCx2601  2.184949e-01  2.136895e-01 -0.4438584387  0.0296356368
## x14MCx2641 -9.455448e-02  1.581050e-01  0.1161023546 -0.1325423977
## x14MCx2645  3.083305e-01 -1.203993e-01  0.0818818472 -0.0639257284
## x14MCx2670  5.027284e-02  4.629939e-02  0.1181161820  0.0707824878
## x14MCx2682  8.777076e-02 -2.805997e-01  0.1175930475 -0.1058771163
## x14MCx2741 -8.261894e-02  8.803669e-02  0.1500631430  0.0276799376
## x14MCx2749 -1.558103e-01  8.031736e-02  0.0800876237 -0.1587684874
## x14MCx2756 -1.518419e-01  1.217791e-01  0.1054625705 -0.0950864449
## x14MCx2818  1.017151e-01  7.154918e-02  0.0874040947  0.0594413022
## x14MCx2842  4.663289e-01 -2.724991e-01 -0.0980949880 -0.1690583525
## x14MCx2903  1.489858e-01  2.381016e-01 -0.1159298628  0.0141013236
## x14MCx2932  2.476530e-01  3.015777e-01 -0.2513950377 -0.0825325261
## x14MCx2945  2.908241e-01 -2.951825e-01  0.0784943685 -0.1228537615
## x14MCx2961 -5.049936e-02  1.313804e-01  0.1490005358 -0.0286811451
## x14MCx2968  1.965363e-01  1.776735e-01 -0.0160837860  0.1000085309
## x14MCx2979  2.570429e-01  2.935386e-01 -0.2478224007 -0.0486293643
## x14MCx2986 -1.255381e-01  9.535763e-02 -0.0174078926 -0.0532952024
## x14MCx3041  2.296124e-02 -3.354335e-01  0.0590144842 -0.1167735594
## x14MCx3050 -6.079373e-02 -3.243375e-01  0.0204327199  0.0427221129
## x14MCx3150 -1.271312e-01  6.597720e-02  0.1302326034  0.0038696642
## x14MCx3229 -1.106142e-02 -8.509077e-02  0.0603500783  0.0373428815
## x14MCx3258  1.598585e-01 -6.302752e-02  0.1260937029 -0.0218588007
## x14MCx3320 -2.054105e-01 -1.057637e-02  0.0685296778 -0.0657341375
## x14MCx3348 -1.644181e-01  4.227053e-02  0.1036057821  0.0373606417
## x14MCx3378  4.367841e-01 -9.554383e-02 -0.1916816038 -0.0128861975
## x14MCx3397  3.816794e-02  1.319561e-01  0.1089961743  0.0438546258
## x14MCx3405 -4.077838e-03  6.749544e-02  0.0922575832  0.1105429451
## x20MCx1115 -2.955430e-01  1.195445e-02 -0.0250586044 -0.1233795790
## x20MCx1122 -1.864629e-01  6.606429e-02  0.0816410347 -0.1230104389
## x20MCx1125 -1.173318e-01 -7.742261e-03  0.0436886073  0.1102368815
## x20MCx1181  1.825618e-01 -3.176077e-01  0.0959123374 -0.0753135730
## x20MCx1184 -1.792190e-01  6.128292e-02  0.0712115547  0.0176978964
## x20MCx1203 -3.187684e-01 -6.624266e-02 -0.0300220837  0.0236897253
## x20MCx1252  3.984498e-01 -2.479758e-01  0.0415254777  0.0079436148
## x20MCx1263 -1.114745e-01  6.093811e-02  0.1827098384  0.0608130192
## x20MCx1264 -2.525519e-01 -2.867165e-02 -0.1073143401 -0.0719985932
## x20MCx1278  5.594862e-03  1.688447e-01  0.1315966576 -0.0427842082
## x20MCx1332 -2.277467e-01  3.823510e-02  0.0725435612 -0.0534370150
## x20MCx1366 -5.483655e-02  3.304419e-02  0.1260072707  0.1797433826
## x20MCx1393  1.151222e-01 -1.330640e-01  0.1217769780  0.1268029877
## x20MCx1424 -3.117285e-01 -7.824505e-02 -0.0163042784  0.0521432676
## x20MCx1469 -4.329498e-02  1.009911e-01  0.0988669583 -0.0216910346
## x20MCx1478 -2.107713e-01  5.837921e-02  0.0510791940 -0.1078292441
## x20MCx1492  2.985117e-01 -7.158640e-02  0.0072602403 -0.0038083394
## x20MCx1559 -1.588255e-01  2.320173e-02  0.1277538539  0.0798915479
## x20MCx1631  1.897550e-01 -2.821051e-01  0.1060161925 -0.0649821674
## x20MCx1634 -1.381112e-01  1.060378e-01  0.0007018628 -0.1520428007
## x20MCx1665  7.811747e-02  6.131107e-02  0.1176740553  0.1497070965
## x20MCx1673  2.928170e-01 -2.739614e-01  0.0200626881 -0.1536212607
## x20MCx1708 -4.530799e-02  7.265573e-02  0.1152971392  0.1892896474
## x20MCx1717 -1.451810e-02  1.338204e-01  0.0358255669 -0.1449025337
## x20MCx1734 -9.962424e-02  3.923740e-02  0.1118560456 -0.0869141268
## x20MCx1756 -5.787285e-02  7.434782e-02  0.0947721505  0.1608987152
## x20MCx1780  3.263648e-01 -2.172435e-01  0.0283750238 -0.0546188976
## x20MCx1790 -2.952561e-01 -6.094299e-02 -0.0819228205 -0.0732581791
## x20MCx1830  3.586136e-01 -3.742605e-01  0.0324172735 -0.0240948190
## x20MCx1837 -3.099465e-01 -2.586239e-02 -0.0888813372 -0.1020677503
## x20MCx1854 -2.397398e-01  2.434705e-02 -0.0218242578 -0.0866445624
## x20MCx1868 -1.616727e-01  7.854554e-02  0.0663856030 -0.0682880281
## x20MCx1871  3.532367e-01  3.456849e-02 -0.0504464751  0.0985922661
## x20MCx1925 -1.693234e-01 -2.563465e-02  0.0792637534  0.1803699965
## x20MCx1941 -1.297398e-01  1.327048e-01  0.0863425412 -0.0646329405
## x20MCx1959  2.495657e-01  2.599380e-01 -0.2478517873  0.0114990762
## x20MCx1986 -7.219804e-02 -2.810166e-02  0.0705189636  0.0668487745
## x20MCx2000 -3.170716e-01 -5.526644e-02 -0.1189647260 -0.0884392606
## x20MCx2016  5.561222e-02 -8.505905e-04  0.1316242429  0.1225867790
## x20MCx2024 -2.471895e-03  2.527536e-02  0.1260497590  0.1335335491
## x20MCx2039  4.348732e-03  5.383609e-03  0.1126066309  0.0398247156
## x20MCx2085 -3.177707e-01 -4.075648e-02 -0.1272594946 -0.0406577114
## x20MCx2118 -1.568546e-01  3.219224e-03  0.0186659348 -0.0349563962
## x20MCx2119  2.444957e-02  1.175589e-01  0.0770006090 -0.0225099426
## x20MCx2233  3.227248e-02 -1.181512e-01  0.0355151544  0.2711073021
## x20MCx2251  1.438537e-01  2.666120e-01  0.0028225900 -0.1277001281
## x20MCx2265 -2.841826e-01  2.732288e-03 -0.0063867717 -0.1201956469
## x20MCx2307  2.371383e-01 -6.896949e-02  0.0736862322  0.1097872080
## x20MCx2328  2.177707e-01  2.905412e-01 -0.2977641850 -0.0790655472
## x20MCx2344  3.498710e-02  1.359923e-01  0.1322591588  0.0622486121
## x20MCx2351 -2.465272e-01 -2.147494e-02  0.0476669217  0.1010079270
## x20MCx2368  2.677496e-01  2.389202e-01 -0.1377290858 -0.0203003030
## x20MCx2465 -1.868159e-01 -8.735403e-02 -0.0412623695  0.0265828351
## x20MCx2483 -3.451514e-01 -7.283567e-02 -0.0746373428 -0.0360425520
## x20MCx2542 -2.688591e-01  7.913090e-04 -0.0018450061 -0.1143861193
## x20MCx2559 -2.101684e-01 -6.888728e-03 -0.1382798726 -0.1518194291
## x20MCx2581 -3.083530e-01 -8.634418e-02 -0.2763550260 -0.1405268645
## x20MCx2628 -1.506205e-02 -1.251346e-01  0.0807707081 -0.0077884148
## x20MCx2631 -1.061912e-01  6.986642e-02  0.1415488727  0.0781463846
## x20MCx2634  1.891322e-01  1.370285e-01 -0.0082081473  0.1358451445
## x20MCx2642  3.337622e-02  1.790927e-01  0.1579744930  0.0498869917
## x20MCx2677  1.021741e-01 -1.810769e-03  0.1156015601  0.1493876555
## x20MCx2717  9.145368e-02 -1.579500e-02  0.0856519951  0.1405544481
## x20MCx2745  2.002860e-01 -3.514716e-01  0.0433844242 -0.1963028415
## x20MCx2759 -1.249822e-01  1.835997e-03  0.0944606144  0.0768752973
## x20MCx2761 -2.367134e-01  2.447899e-02  0.0429229073 -0.0442912880
## x20MCx2773 -2.147090e-01  3.480203e-02  0.0588309658 -0.0583213602
## x20MCx2787 -1.284007e-01  1.233573e-02  0.1305388207  0.0584959417
## x20MCx2857  1.003693e-01 -3.457263e-01  0.0719061100 -0.1031336294
## x20MCx2870 -2.060570e-01  1.818393e-03  0.0628473913  0.0153761231
## x20MCx2885 -8.512035e-02  4.323167e-02  0.0681888664 -0.0778850020
## x20MCx2895  1.622137e-01 -2.193100e-02  0.0898401017  0.0223042956
## x20MCx2896  1.985279e-01 -1.984044e-01  0.1245161103  0.0151933307
## x20MCx2929 -3.230248e-01 -5.697446e-02 -0.1457254300 -0.1033297411
## x20MCx2969 -8.853645e-02  1.185653e-01  0.1489864181  0.0314773996
## x20MCx2975 -3.184444e-01 -6.179663e-02 -0.0150814765 -0.0057658873
## x20MCx2988 -1.960330e-01  7.398584e-02  0.0348255887 -0.1546169908
## x20MCx3020 -3.251000e-01 -3.741954e-02 -0.1574028326 -0.1383778758
## x20MCx3044  1.070383e-01  3.609616e-02  0.1016989603  0.0828031582
## x20MCx3048 -1.565891e-01 -3.302774e-02  0.1012547945  0.0368982730
## x20MCx3094 -1.778093e-01  8.467349e-02  0.0260624427 -0.1841533425
## x20MCx3099 -1.825693e-01 -2.515126e-02  0.0734950822  0.1637483217
## x20MCx3108 -2.296382e-01 -1.978558e-02 -0.0479982814  0.0588871265
## x20MCx3119  1.429351e-01 -1.055781e-01  0.1216123510  0.0926627348
## x20MCx3228 -2.527381e-01 -1.598836e-02 -0.0006052921  0.0042921784
## x20MCx3241 -1.279808e-01  5.537628e-02  0.0280362499  0.0131075662
## x20MCx3308 -4.060444e-02  1.036016e-01  0.0969951288 -0.0310605198
## x20MCx3335 -1.268218e-01  8.786063e-02  0.0970549637  0.0243578883
## x20MCx3337 -8.582710e-02  7.173053e-02  0.1397748998  0.1047211203
## x20MCx3402  1.355672e-01  9.001849e-02  0.0332475748 -0.1965073504
## x30MCx1112 -2.325159e-01 -5.072449e-03 -0.0237263046 -0.1118750284
## x30MCx1116  2.902675e-01 -3.304634e-02 -0.0051211665  0.2074648896
## x30MCx1163  1.906845e-01 -7.046817e-02  0.1425949133  0.0770827796
## x30MCx1170  1.024793e-01  1.221360e-01  0.0958660892 -0.0239626873
## x30MCx1172 -2.369191e-01  4.470509e-02  0.0643429160 -0.0748915013
## x30MCx1180 -2.052719e-01  6.035172e-02  0.0214635109 -0.1305295520
## x30MCx1193  2.089019e-01  1.760566e-01 -0.0387394428  0.0714286474
## x30MCx1196 -2.474211e-02  1.631700e-01  0.0671772793 -0.0042866401
## x30MCx1201  2.363130e-01  4.813792e-02  0.1058220997 -0.0214761668
## x30MCx1226 -3.458556e-02  1.541395e-01  0.0900625894  0.0672585852
## x30MCx1235 -1.862868e-01  2.908360e-02  0.1384076839  0.0094566018
## x30MCx1259  1.342519e-01  3.281670e-03  0.1465187791 -0.0357526195
## x30MCx1266  2.787400e-01  2.910456e-01 -0.3505158000  0.0020566926
## x30MCx1270 -6.516632e-02  5.515852e-02  0.1231131410  0.1342867577
## x30MCx1280  2.374984e-02  2.467845e-01 -0.0908591925 -0.2171991814
## x30MCx1308  1.643940e-03  1.354393e-01  0.0804560539  0.1157796476
## x30MCx1314  3.053625e-01 -2.906408e-02  0.0436083242  0.0488591918
## x30MCx1321  3.423755e-01 -3.731098e-02  0.0450312463 -0.0257815316
## x30MCx1335 -6.928009e-03  9.801211e-02  0.1217065279  0.0353906358
## x30MCx1394 -3.223645e-01 -1.164264e-01 -0.1706317569 -0.0448634440
## x30MCx1405  1.674842e-02  8.155119e-02  0.1231676122  0.2592498265
## x30MCx1415 -1.096948e-01  1.770362e-01  0.0555480534 -0.1390978465
## x30MCx1417 -2.748449e-02  1.386972e-01  0.1086704185 -0.0163069670
## x30MCx1451  2.889128e-01  1.527545e-01 -0.0478843122  0.1095582699
## x30MCx1479  1.281719e-01 -3.943469e-01  0.0150549034  0.0641199499
## x30MCx1503 -2.588778e-02  1.506857e-01  0.0755527201 -0.0612882141
## x30MCx1517 -2.811882e-01 -1.057755e-01 -0.1275083750  0.1280940570
## x30MCx1527  1.860117e-01 -2.090354e-01  0.1171154262 -0.0055394192
## x30MCx1556  8.308309e-02  1.701319e-01  0.1155842421  0.0615152047
## x30MCx1566 -3.767370e-02 -3.582652e-03  0.1127300499  0.1823075831
## x30MCx1569 -5.725182e-02  1.523926e-01  0.1198548472 -0.0084103517
## x30MCx1586 -5.440221e-02  1.480947e-01  0.1020223576 -0.0513616657
## x30MCx1592  9.041511e-02  7.378888e-02  0.0533129967  0.0344484056
## x30MCx1597 -8.309879e-02  6.826575e-02  0.1221020522  0.1116268730
## x30MCx1601  2.766259e-01 -2.495105e-01  0.0843018858 -0.1339470788
## x30MCx1611  3.152574e-02  9.328077e-02  0.1282662175  0.1023935583
## x30MCx1618  2.735661e-01 -2.437828e-01  0.0986126739 -0.1339455849
## x30MCx1636  3.678217e-01  1.003041e-01 -0.1408538962  0.0520473649
## x30MCx1637  3.031932e-01 -1.610776e-01  0.0906069471 -0.0936791861
## x30MCx1646  1.481842e-01  1.748230e-01  0.0443514187  0.0952422405
## x30MCx1649  1.353078e-01  2.388921e-01  0.0080763152 -0.1086879597
## x30MCx1664 -1.154780e-01  9.990534e-02  0.1244479319 -0.1129244818
## x30MCx1712  7.195205e-02  1.860916e-01  0.0650316886 -0.0889112657
## x30MCx1722 -1.752530e-01  1.081583e-01  0.0384185657 -0.1705725847
## x30MCx1744  1.411544e-01  1.523280e-01  0.1028451604  0.0065239143
## x30MCx1748 -1.413274e-01  1.037901e-01  0.0969050043 -0.1084947800
## x30MCx1774  3.471204e-01  2.084312e-02  0.0073315129  0.0532804267
## x30MCx1782  2.635868e-01  6.447215e-02  0.0104270455 -0.0568164771
## x30MCx1786 -2.528255e-01 -2.771457e-02  0.0397803299  0.0163727842
## x30MCx1787  3.123856e-02 -6.011144e-02  0.1290970191  0.0949841040
## x30MCx1791  2.437838e-01  1.829665e-01 -0.1621539988  0.1816328271
## x30MCx1792 -5.013561e-02  1.480117e-01  0.0752423348 -0.0752392761
## x30MCx1824  1.000378e-01  8.000783e-02  0.0916405193  0.0821698594
## x30MCx1828  1.303347e-02  2.256550e-01  0.0785550171 -0.0325558330
## x30MCx1860  3.484769e-01 -2.950696e-02  0.0371343303  0.0033586856
## x30MCx1872  1.513578e-01  1.690114e-01  0.0411678354  0.2010479266
## x30MCx1881 -1.459624e-01 -1.191040e-02  0.0920597911  0.1475293738
## x30MCx1911  1.628590e-01 -3.656296e-01  0.0626595421  0.0362740059
## x30MCx1917 -2.004391e-01 -3.334072e-02  0.0457923657  0.1120358036
## x30MCx1966 -8.891912e-02  1.349271e-01  0.1124091262 -0.0557845974
## x30MCx1972  3.745079e-01 -1.822837e-01 -0.0186698489  0.0779959675
## x30MCx1980  2.714189e-01 -2.917134e-01  0.0624722053 -0.1049366298
## x30MCx1993  1.790218e-01  1.241630e-01  0.0247803496  0.1807405039
## x30MCx1996 -1.222723e-01  1.193650e-01  0.0861275521 -0.0701838984
## x30MCx2009 -1.045853e-01  9.733429e-02  0.1176748214 -0.0093025784
## x30MCx2015  2.203671e-01  9.106284e-02 -0.4802589225  0.0485476783
## x30MCx2022  3.287963e-01  1.645109e-01 -0.1271522881  0.1130941085
## x30MCx2041  2.194107e-01  2.925059e-01 -0.0866954067 -0.0388731948
## x30MCx2081  9.338459e-02  2.000781e-01  0.1084983940  0.0802419973
## x30MCx2092 -2.537727e-01  2.448103e-02  0.0011233819 -0.1876133605
## x30MCx2096 -1.391282e-03  5.131731e-02  0.0458422705  0.2184637859
## x30MCx2099  1.179949e-01  1.904283e-01  0.1279724388  0.0364441008
## x30MCx2107  4.520709e-02  1.920329e-01 -0.0089942694  0.0208489441
## x30MCx2131 -2.458451e-01 -5.971953e-02  0.0552281832  0.1093892102
## x30MCx2132 -7.412816e-02  9.979914e-02  0.1158049355 -0.0458647621
## x30MCx2140  2.742047e-01  9.798020e-02  0.0235823330 -0.0162920687
## x30MCx2149  2.204840e-01  4.281019e-02  0.0689803272 -0.0172955889
## x30MCx2158  7.189428e-02  1.561433e-01  0.0574520109 -0.1562120196
## x30MCx2166  2.155773e-01  2.573982e-01 -0.0313544402  0.0602495651
## x30MCx2168  1.451551e-01  3.006079e-01 -0.0674135054 -0.0657528602
## x30MCx2179 -5.486660e-02 -7.697036e-02  0.1181064581  0.2207295692
## x30MCx2183 -9.548706e-02  1.778378e-02  0.1393946769  0.0397239302
## x30MCx2201  2.810248e-02  1.764747e-01  0.0858169213  0.0728368998
## x30MCx2204  2.628063e-01 -3.269132e-01  0.0291113615 -0.1811102634
## x30MCx2206 -2.604507e-01  1.640488e-02 -0.0559010793 -0.1868447669
## x30MCx2257  1.766523e-01  6.911849e-02  0.0979474330  0.0393337906
## x30MCx2281  2.825272e-01  2.341088e-01 -0.1256419969  0.0548468799
## x30MCx2298  7.129112e-02  1.868672e-01  0.0145648341 -0.1120589358
## x30MCx2312  8.298155e-02  2.412445e-01  0.0547446588 -0.0176931616
## x30MCx2316  1.056602e-01  3.071869e-01  0.0168037334 -0.1090205476
## x30MCx2327  7.505014e-02  2.315327e-01  0.0760147708  0.0390328201
## x30MCx2334  1.315778e-02  1.853453e-01  0.1220242570 -0.0234067127
## x30MCx2349 -2.158066e-01  6.064017e-02  0.0467350561 -0.0218647238
## x30MCx2352 -1.932197e-01  6.651722e-02  0.0491252982 -0.0772989021
## x30MCx2353  2.943132e-01  1.292913e-01 -0.0197413474  0.1361073386
## x30MCx2354 -1.427435e-01  4.365101e-02  0.0666986163 -0.0417248318
## x30MCx2363 -3.865429e-02  1.159349e-01  0.0953334978 -0.0176865940
## x30MCx2414  7.252255e-02  1.278881e-01 -0.0272405307  0.1052020478
## x30MCx2415  2.129329e-01  1.092972e-01  0.0664436475  0.0746067083
## x30MCx2423  2.773709e-01 -9.577370e-02  0.1184447939 -0.0104543424
## x30MCx2425 -5.071430e-02  8.195343e-02  0.1176902420 -0.0213809925
## x30MCx2445  2.703672e-01  2.889949e-01 -0.1995957260  0.0029117798
## x30MCx2450  4.828919e-02 -2.771653e-01  0.0732197819 -0.0229279301
## x30MCx2451 -2.552825e-01  6.667631e-02 -0.0805402275 -0.1877009889
## x30MCx2473 -1.337553e-01  8.387677e-02  0.1153338200 -0.1008902584
## x30MCx2480 -2.256422e-02  3.336977e-03  0.0100192991  0.1675261544
## x30MCx2499 -2.523134e-02  1.118333e-01  0.1222036599  0.0538522143
## x30MCx2501  2.250556e-01 -2.137767e-02  0.0911560312  0.0643904631
## x30MCx2529  2.399052e-01  3.480009e-02 -0.0147451435  0.2003264455
## x30MCx2543 -1.342772e-01  7.872417e-02  0.1289919310 -0.0067946122
## x30MCx2568  2.768237e-01 -8.898982e-02  0.1183240451 -0.1165073173
## x30MCx2570 -1.677260e-01  7.403359e-02  0.0815392658 -0.1428362328
## x30MCx2573  1.675106e-01  2.454489e-01  0.0124295604  0.1316339050
## x30MCx2574 -6.570232e-02  1.025134e-01  0.0696658137  0.0631355496
## x30MCx2605  1.216247e-02  7.504488e-02  0.0517444245  0.0484884405
## x30MCx2619  7.887029e-02  1.071419e-01  0.0933375087 -0.0190647903
## x30MCx2654  3.914673e-01 -3.813075e-01 -0.0381424119 -0.1262949982
## x30MCx2661 -1.431410e-02  1.519553e-01 -0.0152408893 -0.1719871274
## x30MCx2662  6.346022e-02  2.330822e-01  0.0748350549  0.0110816770
## x30MCx2675 -4.995307e-03 -7.879553e-02  0.1652629734  0.0424323339
## x30MCx2676  1.032841e-01  7.551560e-02  0.0223770148 -0.0112228003
## x30MCx2700  3.898870e-02  1.876408e-01  0.1358664502  0.0219970588
## x30MCx2708 -2.032723e-01 -1.323016e-02  0.0561313459  0.0110892012
## x30MCx2720  2.178907e-01  2.807789e-01 -0.0770671880 -0.0665478313
## x30MCx2735 -1.700058e-01  7.326941e-02  0.0876739245  0.0097054515
## x30MCx2746  1.330566e-01  1.673697e-01  0.0858403265  0.0928594374
## x30MCx2760 -7.418053e-02  9.640613e-02  0.1424718233  0.0879274735
## x30MCx2770 -6.060830e-02 -1.392671e-01  0.0333123537  0.1830640224
## x30MCx2775 -2.319031e-01 -2.458882e-03  0.0991730750  0.0599641938
## x30MCx2777  5.654503e-02  1.449301e-01  0.1227132624  0.0660763337
## x30MCx2783  1.065241e-01  2.458484e-01 -0.0297181707 -0.0113660869
## x30MCx2790  2.976214e-03  1.596362e-01  0.1498353331 -0.0276839609
## x30MCx2811  1.857455e-01  1.813842e-01  0.0148179229  0.0879778511
## x30MCx2819  2.782877e-01  2.569729e-01 -0.2858310084  0.0738896837
## x30MCx2822 -1.200029e-01  1.353869e-01  0.0388540361 -0.1939878568
## x30MCx2828  1.341340e-03  1.353013e-01  0.0944226910  0.0202439864
## x30MCx2840  3.655762e-01 -4.855756e-02 -0.1830905987  0.1491581465
## x30MCx2881 -8.734583e-02  2.385212e-02 -0.0077082704 -0.2169187007
## x30MCx2909  3.388334e-01  1.641439e-01 -0.1531087070  0.1061843433
## x30MCx2911 -2.064889e-01  6.051201e-02  0.0979191725 -0.0554541163
## x30MCx2920  3.118480e-01 -3.393279e-01  0.0312397245 -0.1023695026
## x30MCx2941 -1.294793e-01  1.597465e-02  0.1105035103  0.1277476241
## x30MCx2954  3.690898e-02  7.692512e-02  0.0741750440  0.0793234445
## x30MCx2966 -2.715984e-02  1.095757e-01  0.1519593999  0.0685886013
## x30MCx2990 -5.657120e-02  5.603704e-02  0.1270188838  0.0941768183
## x30MCx2995 -1.100378e-01  1.657650e-01  0.0772939999 -0.1022658986
## x30MCx3000 -5.671337e-02  7.251937e-02  0.1467388875 -0.0184380346
## x30MCx3017  2.626547e-01 -2.714804e-01  0.0740691062 -0.1636698426
## x30MCx3025 -1.236736e-01  1.222515e-01 -0.0053628227 -0.1769830211
## x30MCx3030 -5.804154e-02  1.019160e-01  0.1413810896 -0.0209452566
## x30MCx3058  2.824576e-01 -3.335505e-01  0.0253228365 -0.1838149190
## x30MCx3061 -1.180793e-01  1.234840e-01  0.0821753729 -0.0595464373
## x30MCx3065 -4.577887e-02  5.237681e-02  0.1090962393  0.2017800014
## x30MCx3070 -2.385152e-01  6.408121e-02  0.0369217316 -0.1797716754
## x30MCx3083  1.806799e-01  1.144123e-01  0.0163032686 -0.0080915902
## x30MCx3086 -1.548995e-01  9.031357e-02  0.1190892368 -0.0907428427
## x30MCx3091  1.688718e-02  1.587074e-01  0.1008270060  0.0869206046
## x30MCx3100  2.130051e-01  1.372755e-01 -0.0567699435  0.2226014309
## x30MCx3103  2.458461e-01  2.246567e-01 -0.1481598308  0.0709973190
## x30MCx3118  3.378027e-02  2.449123e-01  0.0217601447 -0.0683786918
## x30MCx3128  2.016360e-01  1.330127e-01 -0.0554602953 -0.0064214150
## x30MCx3140 -2.062019e-02  2.484146e-02  0.0550703659 -0.1508432415
## x30MCx3152 -1.971587e-01  4.596662e-02  0.0714835315 -0.0467280853
## x30MCx3160  3.163260e-01  1.074531e-01 -0.4530619410  0.0322573742
## x30MCx3171 -1.797017e-01  2.934829e-03  0.0762340998  0.0357455003
## x30MCx3180 -4.522942e-02  1.340218e-01  0.1608139947 -0.0257652928
## x30MCx3183  1.483789e-01  1.551451e-01  0.0456890299  0.0882711319
## x30MCx3214 -1.546826e-01  9.374890e-02  0.0852720578 -0.0925626451
## x30MCx3221 -1.372912e-01  3.595178e-02  0.1256223073 -0.0207845969
## x30MCx3237 -4.203506e-02  1.136766e-01  0.1069604178 -0.0074338496
## x30MCx3240  3.833268e-01 -3.051677e-01 -0.0324100252 -0.1041891455
## x30MCx3243  2.890840e-01 -3.315231e-01  0.0060491800 -0.1936659977
## x30MCx3263 -1.616404e-01  4.186377e-02 -0.0201109759 -0.1002145674
## x30MCx3291  1.182554e-01  1.679735e-01  0.0853078171  0.0788619319
## x30MCx3314  2.372268e-01  2.135888e-01 -0.4487091040  0.0163933189
## x30MCx3340  4.563748e-02  1.818348e-01  0.0938475132 -0.0567998445
## x30MCx3345  1.696644e-01  9.512596e-02  0.0897249550  0.0393707437
## x30MCx3366  4.328523e-03  5.639677e-02  0.1243854599  0.1823800224
## x30MCx3369  3.404575e-01  1.304667e-01 -0.0679829636 -0.0746014755
## x30MCx3375 -2.170751e-01  1.862799e-02  0.0460082741  0.0442471761
## x30MCx3376 -3.172396e-03  1.270457e-01  0.1579557030  0.0693563314
## x30MCx3379 -1.712746e-01 -2.690364e-02  0.0991714910  0.1883062500
## x30MCx3384  3.700006e-01 -1.540177e-01 -0.0045992242 -0.0099861209
## x30MCx3414  3.079596e-01 -2.300821e-01  0.0998128733 -0.1008949540
## x10MCx1135  2.804942e-01 -3.852157e-01  0.0067833530 -0.0951684701
## x10MCx1140 -1.890830e-01  1.533754e-02  0.0586077936  0.0061660660
## x10MCx1144 -2.382416e-01 -6.248317e-02 -0.2602923763 -0.1657877148
## x10MCx1155  3.558044e-01 -1.372797e-01 -0.0758658498  0.0231727356
## x10MCx1165 -1.635378e-01 -1.197450e-02  0.0712086711 -0.0210353857
## x10MCx1208 -2.500281e-01 -3.136612e-02 -0.0056581204 -0.0715635217
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## x13MCx2229 -2.768020e-01 -5.049871e-02  0.0033708236 -0.0214542421
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## x13MCx3092  3.430902e-01 -3.085686e-01  0.0455050012 -0.1347720761
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## x30MCx1188 -3.034925e-01 -1.352697e-01 -0.0648195663  0.0901024679
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## x30MCx1296 -1.786260e-01  1.934502e-03  0.0909892001  0.0574901846
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## x30MCx1358 -2.905850e-01 -1.709596e-02 -0.0500887887 -0.0799667736
## x30MCx1370  1.570198e-01  1.421349e-01  0.0369488810  0.1855851969
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## x30MCx1401 -9.789431e-02 -2.157271e-02  0.0769378958  0.0966951406
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## x30MCx1425 -1.390891e-01  6.567031e-02  0.1134549590 -0.0632374486
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## x30MCx1449 -1.489660e-01 -1.517216e-02  0.0840517282  0.0771242132
## x30MCx1452 -2.167701e-01 -2.648803e-02  0.0095781154  0.1225262735
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## x30MCx1477 -1.269942e-01  7.585744e-02  0.0137370638 -0.0124397768
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## x30MCx1522  8.014783e-02  2.159671e-01  0.1216358382  0.0615729462
## x30MCx1524  2.072087e-01  8.928884e-02  0.0470823459  0.1287876114
## x30MCx1525 -4.831520e-03  1.392743e-01  0.1479489848 -0.0245193845
## x30MCx1544 -3.909881e-02 -3.383703e-01 -0.1148318214  0.0418730774
## x30MCx1554 -2.197786e-01 -9.732095e-02 -0.1085510952  0.2451345481
## x30MCx1573 -3.232328e-01 -5.000897e-02 -0.0859286301 -0.0648868067
## x30MCx1575  2.723558e-01 -1.807734e-01  0.0805460890  0.0578823177
## x30MCx1590  2.565798e-01  2.268993e-01 -0.4451204038  0.0253189061
## x30MCx1594 -2.392677e-01  7.248068e-02 -0.0214146736 -0.1697723195
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## x30MCx1609 -5.373654e-02  3.236031e-02  0.0210734665  0.1869940265
## x30MCx1644 -1.233436e-01  1.001956e-01  0.1264178324 -0.0786694538
## x30MCx1662 -3.361886e-01 -1.389021e-01 -0.1383204134  0.0350977461
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## x30MCx1682  3.381365e-01 -3.647295e-01 -0.0396980561 -0.1031431574
## x30MCx1683 -1.303010e-01  4.672845e-03  0.1535044671  0.1268730011
## x30MCx1686 -2.615837e-01 -5.552623e-02  0.0396237715  0.0497827516
## x30MCx1688 -3.198724e-01 -1.779221e-01 -0.2538272548  0.1384082725
## x30MCx1691  3.697131e-02 -9.895982e-02  0.1696998478 -0.0054481913
## x30MCx1696 -3.087747e-01 -5.511000e-02 -0.0836835716 -0.0831675799
## x30MCx1701  2.289408e-01  2.561198e-01 -0.3436157076 -0.0615494002
## x30MCx1707  9.303424e-02  9.889072e-02  0.1330992193  0.1428372577
## x30MCx1741  9.935221e-03 -1.915784e-01  0.0728061513 -0.1135308495
## x30MCx1750 -1.518935e-01 -1.968968e-01 -0.1684143835  0.2529518884
## x30MCx1754  4.338573e-02  1.298534e-01  0.1423213394  0.0531514929
## x30MCx1761  1.743641e-03  1.932281e-01  0.0623145230 -0.0147445507
## x30MCx1762 -1.840575e-01 -2.052558e-01 -0.2663739975  0.1598348881
## x30MCx1765 -6.644447e-02 -8.423714e-03  0.0495864641  0.2350349223
## x30MCx1767 -5.908189e-02  2.212372e-04  0.1169645571  0.2032317593
## x30MCx1779 -1.195076e-01  1.359417e-01  0.0352657178 -0.0976166863
## x30MCx1796 -1.468453e-01  2.496168e-02  0.0423841068 -0.0322025828
## x30MCx1813  3.106671e-01 -3.452507e-01  0.0184422502 -0.1658778441
## x30MCx1832 -2.122050e-01  2.793610e-02  0.0980014467 -0.0384708101
## x30MCx1838 -1.486447e-02  1.305835e-01  0.1071114459 -0.0788773244
## x30MCx1840 -1.757750e-01 -1.501402e-01 -0.0544636440  0.2685098879
## x30MCx1851  1.878084e-01  2.794484e-01 -0.0096539134  0.0309683443
## x30MCx1852 -6.156853e-02  3.719165e-02 -0.0135883479  0.1715135213
## x30MCx1856 -2.436431e-01 -1.666986e-01 -0.2392758121  0.2325094440
## x30MCx1885 -2.442629e-01 -1.839351e-01 -0.3237316491  0.2120823609
## x30MCx1902 -3.310953e-02 -7.018753e-02  0.0060300597  0.1645909888
## x30MCx1919  1.680970e-01  1.165536e-01  0.0112925251  0.0411797850
## x30MCx1924  2.015994e-01  2.433224e-01 -0.3647968010 -0.0423026558
## x30MCx1930  3.203566e-02  4.660538e-02  0.0886709188  0.1352087368
## x30MCx1935  2.797722e-01 -1.046180e-02  0.0478497493 -0.0445340599
## x30MCx1938  2.180399e-01  1.501764e-01 -0.4808479458  0.0597757225
## x30MCx1942 -2.413866e-01 -6.911333e-02  0.0652741197  0.0762405227
## x30MCx1956  4.378101e-01 -2.412779e-01 -0.1708917102 -0.1469050299
## x30MCx1957 -8.733451e-02 -3.571470e-01 -0.1232735025  0.1057091569
## x30MCx1969  6.362311e-02  1.149287e-01  0.0704156878  0.1407563130
## x30MCx1975  2.066918e-01  2.052779e-02  0.0763364422  0.1160900557
## x30MCx1976 -1.092652e-01 -3.604228e-01 -0.0402322590  0.0021825530
## x30MCx1987 -3.615304e-02 -3.599091e-01 -0.0374142187  0.1006689392
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## x30MCx2020  1.733579e-01 -2.653305e-01  0.1493907693  0.0535691726
## x30MCx2023  1.804908e-01 -3.136318e-01  0.0938278725 -0.1491117970
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## x30MCx2065 -1.171679e-01  3.389643e-02  0.1598629750 -0.0032947801
## x30MCx2075 -1.620714e-01  3.713678e-02  0.1112920745  0.0153618661
## x30MCx2080 -6.359883e-02  1.785006e-01  0.0720119171 -0.0454652578
## x30MCx2082 -3.052662e-01 -1.546641e-01 -0.2279972181  0.0997328357
## x30MCx2089 -1.847771e-01  1.035572e-01  0.0060260388 -0.1533140486
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## x30MCx2121 -1.816070e-01 -4.093476e-02  0.0634389081  0.1318311571
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## x30MCx2261  1.050862e-01 -3.990512e-01  0.0008443310  0.1934530426
## x30MCx2280  2.207659e-01 -2.103548e-01  0.0965459618  0.0875593132
## x30MCx2296 -3.837290e-02  9.384019e-02  0.1492251838  0.0366604076
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## x30MCx2308 -2.950621e-02 -2.273849e-02  0.0853587940  0.1077555100
## x30MCx2314 -1.671311e-01  1.934254e-02  0.0624108894  0.1354079106
## x30MCx2318  1.006425e-01  5.585600e-02  0.1195595159  0.0537398895
## x30MCx2364 -1.006962e-02  1.056323e-01 -0.0281593403 -0.2346494005
## x30MCx2369 -1.191759e-01 -3.513374e-01 -0.1819790123  0.0867720904
## x30MCx2394  1.208339e-01  8.482166e-03  0.1082624859 -0.0434694498
## x30MCx2403 -2.360503e-01 -1.854546e-01 -0.3539608346  0.1866026652
## x30MCx2410 -2.415098e-01 -5.735199e-02 -0.1071949451  0.0149328688
## x30MCx2418  2.132272e-01  1.621192e-01 -0.4982681066  0.0469940266
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## x30MCx2434 -2.348652e-01 -1.787011e-01 -0.1860663526  0.1998730723
## x30MCx2488 -3.050744e-01 -1.476378e-01 -0.1696841012  0.1599019373
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## x30MCx2515 -7.572158e-02  1.379860e-01 -0.0945481130 -0.2205134499
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## x30MCx2532 -2.502887e-01 -1.750949e-01 -0.3592636614  0.0874942378
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## x30MCx2554 -2.120585e-01  6.333914e-02  0.0848793124 -0.0372655605
## x30MCx2558 -3.090234e-02  5.284503e-02  0.0792548889  0.0049245779
## x30MCx2567  2.692346e-01  3.001117e-01 -0.1979936093 -0.0203316482
## x30MCx2584  9.633262e-02  2.482819e-01  0.0433844547 -0.0880100388
## x30MCx2586  1.370495e-01  1.944259e-01  0.0675584439 -0.0215205116
## x30MCx2592 -1.708331e-01  3.758318e-03  0.0756241054  0.0638720679
## x30MCx2595  1.583490e-03  2.107889e-01 -0.0178189953 -0.1779909939
## x30MCx2618  4.145323e-01 -3.967170e-01 -0.0934507195 -0.2215630829
## x30MCx2648  1.466153e-01 -1.613805e-01  0.1550625591 -0.0337314414
## x30MCx2656  2.189884e-01 -2.580495e-01  0.1109656506 -0.0984802636
## x30MCx2671  1.638918e-01  3.385702e-02  0.0361256622 -0.1501317445
## x30MCx2684  3.314970e-01  1.224748e-01 -0.0975071439  0.0718295181
## x30MCx2690 -1.173716e-01 -1.441424e-01 -0.0466864448  0.2499650731
## x30MCx2715 -2.316711e-01 -7.950816e-02 -0.0564277801  0.0952204482
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## x30MCx2727 -2.537712e-01 -1.227220e-02  0.0236799416  0.0634105311
## x30MCx2731  2.026533e-01  1.896676e-01 -0.4643115051  0.0085572910
## x30MCx2774  2.008039e-01 -3.664793e-01  0.0700277521 -0.0036189032
## x30MCx2780  2.401108e-01  3.074513e-01 -0.1413865906 -0.0409760159
## x30MCx2785  1.110960e-01  1.772408e-01  0.0496064950  0.1608989020
## x30MCx2788 -2.671016e-01 -2.052721e-01 -0.2811674387  0.1505511658
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## x30MCx2836 -8.052767e-02 -1.074343e-01 -0.0160277996  0.0021811552
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## x10MCx2012  0.0339690900
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## x10MCx2766  0.0556241598
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## x10MCx2908  0.0086236963
## x10MCx2991  0.0638572300
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## x10MCx3238 -0.1347965578
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## x10MCx3277 -0.0787588233
## x10MCx3287  0.0329898768
## x10MCx3318 -0.0299336280
## x10MCx3322  0.0781463518
## x11MCx1159 -0.0619528206
## x11MCx1329 -0.0883278148
## x11MCx1383 -0.0319879053
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## x11MCx1588 -0.1550774574
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## x11MCx1874  0.0171696290
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## x11MCx2191 -0.0608027093
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## x11MCx2302 -0.1255656828
## x11MCx2379 -0.0909855995
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## x11MCx2539  0.1126116760
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## x11MCx2768 -0.0387996181
## x11MCx2847 -0.0637109932
## x11MCx2889 -0.1217085857
## x11MCx2897 -0.0688260274
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## x11MCx3134 -0.0257687526
## x11MCx3181  0.0505712127
## x11MCx3193 -0.0110871269
## x11MCx3248 -0.0537455257
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## x12MCx1212  0.0137914404
## x12MCx1237  0.0289641953
## x12MCx1242  0.0436498766
## x12MCx1244 -0.0929615588
## x12MCx1289 -0.1251654438
## x12MCx1320 -0.0403094786
## x12MCx1347  0.0443293702
## x12MCx1353  0.1265354952
## x12MCx1356  0.0186624871
## x12MCx1368 -0.0335926547
## x12MCx1377 -0.1031224655
## x12MCx1392 -0.0026960612
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## x12MCx1446  0.0147102892
## x12MCx1480  0.0555118959
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## x12MCx1642 -0.1463826724
## x12MCx1651 -0.1124993726
## x12MCx1652 -0.0063439622
## x12MCx1672  0.0324972564
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## x12MCx2202  0.1017305535
## x12MCx2212  0.1387854902
## x12MCx2259 -0.0419964947
## x12MCx2285  0.0914894721
## x12MCx2291  0.0587508611
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## x12MCx2323 -0.1630379785
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## x12MCx2380  0.1685647637
## x12MCx2447  0.1356983943
## x12MCx2454  0.0625156367
## x12MCx2489  0.0556860357
## x12MCx2496  0.0485651651
## x12MCx2522 -0.0589938945
## x12MCx2530 -0.0554802320
## x12MCx2576  0.0738345330
## x12MCx2667 -0.1157054659
## x12MCx2701  0.0957922704
## x12MCx2736 -0.0258181470
## x12MCx2763  0.0139306326
## x12MCx2778  0.0565947314
## x12MCx2798  0.1148342628
## x12MCx2849 -0.0240759486
## x12MCx2993 -0.1245906284
## x12MCx3006 -0.0222401009
## x12MCx3026 -0.1504893498
## x12MCx3046 -0.0401025959
## x12MCx3072 -0.0544035374
## x12MCx3082 -0.2060042977
## x12MCx3113 -0.0603508744
## x12MCx3117 -0.0713444441
## x12MCx3125 -0.2199241360
## x12MCx3230  0.1089242221
## x12MCx3272 -0.0410569335
## x12MCx3309  0.1102689744
## x12MCx3333 -0.0613543093
## x12MCx3342  0.0197063889
## x12MCx3344  0.0662121207
## x12MCx3380  0.0918184725
## x12MCx3392 -0.0705768860
## x12MCx3424 -0.0052875772
## x13MCx1175  0.0234137882
## x13MCx1231  0.0291268721
## x13MCx1299 -0.0608656399
## x13MCx1419 -0.0065076871
## x13MCx1506 -0.0498546732
## x13MCx1608  0.0164898156
## x13MCx1783 -0.0550067944
## x13MCx1887 -0.0665756559
## x13MCx2071  0.0151770207
## x13MCx2129  0.1126246633
## x13MCx2229 -0.0584958963
## x13MCx2582 -0.0398918173
## x13MCx3092  0.0871758184
## x13MCx3274 -0.0052903685
## x13MCx3399 -0.0242460322
## x14MCx1338  0.0059732039
## x14MCx1407 -0.0254555481
## x14MCx2102  0.1295519979
## x14MCx2548  0.0007880420
## x14MCx2875  0.0621910136
## x30MCx1130  0.0433500742
## x30MCx1137 -0.1730373988
## x30MCx1139  0.0715513689
## x30MCx1169  0.0547095796
## x30MCx1183 -0.1059561191
## x30MCx1188 -0.0142406750
## x30MCx1195 -0.0686346791
## x30MCx1197  0.0846870233
## x30MCx1199 -0.0187684356
## x30MCx1204 -0.0205073426
## x30MCx1210 -0.0108998875
## x30MCx1214  0.0525950937
## x30MCx1217  0.0075273682
## x30MCx1248 -0.0710478982
## x30MCx1253  0.0858747510
## x30MCx1262  0.0561280890
## x30MCx1271 -0.1573070645
## x30MCx1276  0.0811701189
## x30MCx1293  0.1199214228
## x30MCx1296 -0.0029442383
## x30MCx1312  0.0647307547
## x30MCx1331 -0.0856828831
## x30MCx1346  0.1208790040
## x30MCx1358 -0.0991656947
## x30MCx1370 -0.0870305044
## x30MCx1371  0.0232437340
## x30MCx1372  0.0174770711
## x30MCx1380  0.1220926503
## x30MCx1400 -0.1278355788
## x30MCx1401 -0.0151144592
## x30MCx1406  0.0005065483
## x30MCx1423 -0.0005387488
## x30MCx1425  0.0987115190
## x30MCx1430 -0.0372158072
## x30MCx1449  0.0502641300
## x30MCx1452 -0.0325120925
## x30MCx1461  0.1800823055
## x30MCx1474 -0.0557888013
## x30MCx1477 -0.0201444858
## x30MCx1509  0.0227873637
## x30MCx1522 -0.0185222754
## x30MCx1524 -0.1056157230
## x30MCx1525  0.0365487868
## x30MCx1544  0.1249338022
## x30MCx1554 -0.0778258138
## x30MCx1573 -0.1024489912
## x30MCx1575 -0.0608595885
## x30MCx1590  0.1380461075
## x30MCx1594 -0.1018052919
## x30MCx1607 -0.1442679797
## x30MCx1609  0.0163531265
## x30MCx1644  0.0152955339
## x30MCx1662 -0.0027336768
## x30MCx1674  0.0070623248
## x30MCx1682  0.0034019306
## x30MCx1683  0.0884832363
## x30MCx1686  0.0549854106
## x30MCx1688 -0.0365498680
## x30MCx1691 -0.0219958945
## x30MCx1696 -0.0546310059
## x30MCx1701  0.1289513034
## x30MCx1707 -0.0166186196
## x30MCx1741 -0.0645391439
## x30MCx1750  0.0060262975
## x30MCx1754  0.0676680936
## x30MCx1761 -0.1280171222
## x30MCx1762 -0.0924490611
## x30MCx1765 -0.0370824602
## x30MCx1767  0.0101734899
## x30MCx1779 -0.0059672246
## x30MCx1796 -0.0044706897
## x30MCx1813  0.0436389609
## x30MCx1832  0.0438623484
## x30MCx1838  0.0826219404
## x30MCx1840  0.1041781838
## x30MCx1851 -0.0306961400
## x30MCx1852 -0.0706248965
## x30MCx1856 -0.0019481123
## x30MCx1885 -0.0141305557
## x30MCx1902 -0.0178684017
## x30MCx1919  0.0780859451
## x30MCx1924  0.1384999886
## x30MCx1930  0.0378644117
## x30MCx1935 -0.1123819177
## x30MCx1938  0.1421164126
## x30MCx1942  0.0384667988
## x30MCx1956 -0.1917105442
## x30MCx1957  0.1164808002
## x30MCx1969 -0.0536994401
## x30MCx1975 -0.1786784184
## x30MCx1976  0.0974748409
## x30MCx1987  0.2043189302
## x30MCx1990 -0.0135190660
## x30MCx2004 -0.2017932386
## x30MCx2020  0.0484364252
## x30MCx2023  0.0889520331
## x30MCx2052  0.0053375906
## x30MCx2065  0.0874359214
## x30MCx2075  0.0638437222
## x30MCx2080 -0.0112113724
## x30MCx2082 -0.0512217649
## x30MCx2089 -0.0692031487
## x30MCx2116  0.1406107250
## x30MCx2121 -0.0074040463
## x30MCx2128  0.0765499064
## x30MCx2137  0.0173913050
## x30MCx2154  0.0598010565
## x30MCx2156  0.0096754796
## x30MCx2164  0.0705771482
## x30MCx2165  0.0479561462
## x30MCx2180  0.0356415073
## x30MCx2181 -0.1197554574
## x30MCx2197  0.0273034277
## x30MCx2222 -0.0457193892
## x30MCx2226 -0.0279243020
## x30MCx2241  0.0818647202
## x30MCx2255 -0.0387509744
## x30MCx2261  0.1311583731
## x30MCx2280 -0.0328187536
## x30MCx2296  0.1451752342
## x30MCx2303 -0.0586278499
## x30MCx2308  0.0461119760
## x30MCx2314 -0.0882122899
## x30MCx2318 -0.1137184448
## x30MCx2364  0.0540517853
## x30MCx2369  0.1325626216
## x30MCx2394 -0.1863644697
## x30MCx2403 -0.0058687369
## x30MCx2410  0.0437113015
## x30MCx2418  0.1664029283
## x30MCx2432 -0.1306229641
## x30MCx2434  0.0719124696
## x30MCx2488 -0.0438306274
## x30MCx2512 -0.0508378524
## x30MCx2515 -0.0137820757
## x30MCx2516 -0.1600155858
## x30MCx2532  0.0001059233
## x30MCx2549 -0.0525178695
## x30MCx2554  0.0103670347
## x30MCx2558  0.0205473648
## x30MCx2567  0.0963077988
## x30MCx2584  0.0330154752
## x30MCx2586  0.0985196129
## x30MCx2592  0.0974514055
## x30MCx2595  0.0334242553
## x30MCx2618  0.0244877647
## x30MCx2648 -0.0552964545
## x30MCx2656  0.0285097278
## x30MCx2671 -0.0882558155
## x30MCx2684 -0.1210553082
## x30MCx2690  0.1133869767
## x30MCx2715 -0.0441366436
## x30MCx2719  0.1309721251
## x30MCx2723  0.0463786609
## x30MCx2724 -0.0032557175
## x30MCx2727 -0.0629921016
## x30MCx2731  0.1882757252
## x30MCx2774  0.1678301928
## x30MCx2780  0.0491828116
## x30MCx2785 -0.0801547188
## x30MCx2788  0.0351008179
## x30MCx2792 -0.0080767752
## x30MCx2836 -0.1640342620
## x30MCx2837  0.1450747776
## x30MCx2855  0.0747575761
## x30MCx2871  0.0325528359
## x30MCx2890 -0.0803043102
## x30MCx2898  0.0068772353
## x30MCx2935  0.0416440514
## x30MCx2940 -0.1270963712
## x30MCx2944  0.1434105279
## x30MCx2953 -0.0588198889
## x30MCx2956 -0.0048730929
## x30MCx2958  0.0682753889
## x30MCx2970 -0.0466191684
## x30MCx2974  0.0615508833
## x30MCx2977 -0.2065179411
## x30MCx2982  0.1120075060
## x30MCx2983 -0.0425467393
## x30MCx3003 -0.0562771809
## x30MCx3007  0.1025109280
## x30MCx3015  0.0646329747
## x30MCx3018 -0.0483933802
## x30MCx3038 -0.0568814471
## x30MCx3045  0.0884206553
## x30MCx3053  0.1727159062
## x30MCx3064  0.0002883757
## x30MCx3066  0.0440561021
## x30MCx3087  0.0677569181
## x30MCx3120  0.0439306927
## x30MCx3131 -0.0702221841
## x30MCx3137  0.0120565393
## x30MCx3143 -0.1289596220
## x30MCx3147 -0.0464375344
## x30MCx3154 -0.0455718121
## x30MCx3155  0.0393896315
## x30MCx3161  0.0565304014
## x30MCx3186  0.0445885528
## x30MCx3187  0.0622811576
## x30MCx3203  0.1433267972
## x30MCx3208 -0.0526562406
## x30MCx3215  0.1117337765
## x30MCx3220 -0.0137698369
## x30MCx3225 -0.0070201983
## x30MCx3244 -0.0209581333
## x30MCx3249  0.0333427548
## x30MCx3256 -0.0600838895
## x30MCx3259 -0.0546726241
## x30MCx3260 -0.0730396832
## x30MCx3270  0.0312218134
## x30MCx3279  0.0836207158
## x30MCx3285 -0.1619798635
## x30MCx3297 -0.0863625650
## x30MCx3305 -0.0422144266
## x30MCx3353  0.1688539705
## x30MCx3360 -0.1442027617
## x30MCx3367 -0.0348649565
## x30MCx3372  0.1692845866
## x30MCx3382  0.0232900036
## x30MCx1731  0.0464763463
## x30MCx2868 -0.0674331418
## x30MCx3184  0.0311122804
## x10MCx1626 -0.0389629535
## x10MCx2535  0.1284911985
## x12MCx1124 -0.0442745147
## x12MCx1288 -0.1351849247
## x12MCx1361 -0.1022660409
## x12MCx1413 -0.0173978016
## x12MCx1528  0.0241638476
## x12MCx1700 -0.0503927110
## x12MCx1743 -0.0939252314
## x12MCx2383 -0.0695764297
## x12MCx2466  0.0326348339
## x12MCx2493 -0.0346958220
## x12MCx2938 -0.1620486762
## x12MCx2996 -0.0830577949
## x12MCx3165 -0.1258902553
## 
## $adjusted_R2
## [1] 0.02197768
## 
## $p_value
##        value 
## 0.0002102734 
## 
## $plot

## 
## $variance_explained
##   [1]  1.316463e-01  8.791782e-02  6.070580e-02  4.061210e-02  2.252611e-02
##   [6]  2.104784e-02  1.843789e-02  1.656696e-02  1.458388e-02  1.454809e-02
##  [11]  1.352907e-02  1.197837e-02  1.178440e-02  1.089292e-02  1.069403e-02
##  [16]  9.496000e-03  9.238972e-03  8.624055e-03  8.477190e-03  8.136118e-03
##  [21]  7.900684e-03  7.544680e-03  7.041813e-03  7.020106e-03  6.950051e-03
##  [26]  6.779097e-03  6.458609e-03  6.284013e-03  6.093493e-03  5.989312e-03
##  [31]  5.871947e-03  5.656821e-03  5.505055e-03  5.409516e-03  5.205504e-03
##  [36]  5.130508e-03  5.054828e-03  4.921216e-03  4.848814e-03  4.775938e-03
##  [41]  4.744052e-03  4.558359e-03  4.435329e-03  4.419319e-03  4.284471e-03
##  [46]  4.253288e-03  4.203619e-03  4.135987e-03  3.978370e-03  3.888048e-03
##  [51]  3.830749e-03  3.722777e-03  3.707220e-03  3.595947e-03  3.477473e-03
##  [56]  3.393218e-03  3.372234e-03  3.313880e-03  3.300356e-03  3.297457e-03
##  [61]  3.204515e-03  3.187645e-03  3.146543e-03  3.046335e-03  3.029572e-03
##  [66]  2.948711e-03  2.869752e-03  2.846201e-03  2.798054e-03  2.761581e-03
##  [71]  2.711156e-03  2.694204e-03  2.678416e-03  2.619781e-03  2.590089e-03
##  [76]  2.576533e-03  2.556955e-03  2.517792e-03  2.482387e-03  2.465253e-03
##  [81]  2.391454e-03  2.380467e-03  2.349603e-03  2.317591e-03  2.292993e-03
##  [86]  2.244432e-03  2.201246e-03  2.176237e-03  2.137539e-03  2.114898e-03
##  [91]  2.102209e-03  2.086447e-03  2.045495e-03  2.018132e-03  2.015043e-03
##  [96]  1.984255e-03  1.972571e-03  1.959399e-03  1.930837e-03  1.911272e-03
## [101]  1.867467e-03  1.866874e-03  1.844323e-03  1.816399e-03  1.800079e-03
## [106]  1.794235e-03  1.742653e-03  1.725208e-03  1.699920e-03  1.679066e-03
## [111]  1.668199e-03  1.654922e-03  1.632481e-03  1.630984e-03  1.616888e-03
## [116]  1.599127e-03  1.566123e-03  1.555522e-03  1.548914e-03  1.521242e-03
## [121]  1.504874e-03  1.477656e-03  1.471679e-03  1.449708e-03  1.434238e-03
## [126]  1.417569e-03  1.410139e-03  1.395020e-03  1.381305e-03  1.372304e-03
## [131]  1.357228e-03  1.345661e-03  1.323643e-03  1.302438e-03  1.296984e-03
## [136]  1.279335e-03  1.267428e-03  1.257562e-03  1.252753e-03  1.250548e-03
## [141]  1.242068e-03  1.233749e-03  1.217592e-03  1.204891e-03  1.190306e-03
## [146]  1.171906e-03  1.162203e-03  1.152628e-03  1.142062e-03  1.134062e-03
## [151]  1.120080e-03  1.107951e-03  1.095032e-03  1.090764e-03  1.082744e-03
## [156]  1.077073e-03  1.071806e-03  1.057155e-03  1.043707e-03  1.034459e-03
## [161]  1.017839e-03  1.007814e-03  9.948641e-04  9.836269e-04  9.792509e-04
## [166]  9.692401e-04  9.593030e-04  9.458579e-04  9.418379e-04  9.291078e-04
## [171]  9.204749e-04  9.192496e-04  9.079515e-04  8.945400e-04  8.878028e-04
## [176]  8.697727e-04  8.678683e-04  8.593510e-04  8.528763e-04  8.472761e-04
## [181]  8.405422e-04  8.364890e-04  8.225029e-04  8.178495e-04  8.072307e-04
## [186]  8.037636e-04  7.990687e-04  7.922065e-04  7.792900e-04  7.698277e-04
## [191]  7.651688e-04  7.557323e-04  7.451649e-04  7.431701e-04  7.393398e-04
## [196]  7.339185e-04  7.247650e-04  7.117815e-04  7.085448e-04  6.996245e-04
## [201]  6.956164e-04  6.868622e-04  6.803528e-04  6.738690e-04  6.696737e-04
## [206]  6.651871e-04  6.585888e-04  6.535347e-04  6.469682e-04  6.401394e-04
## [211]  6.344943e-04  6.265144e-04  6.258325e-04  6.176981e-04  6.126608e-04
## [216]  6.065525e-04  6.008929e-04  5.909415e-04  5.884977e-04  5.775983e-04
## [221]  5.723022e-04  5.659442e-04  5.634895e-04  5.573741e-04  5.509255e-04
## [226]  5.493267e-04  5.422943e-04  5.404386e-04  5.345800e-04  5.301037e-04
## [231]  5.242284e-04  5.217900e-04  5.124943e-04  5.085261e-04  4.993541e-04
## [236]  4.942121e-04  4.915683e-04  4.845352e-04  4.817210e-04  4.741649e-04
## [241]  4.672686e-04  4.633144e-04  4.607932e-04  4.587590e-04  4.518405e-04
## [246]  4.489611e-04  4.473554e-04  4.415630e-04  4.304780e-04  4.245584e-04
## [251]  4.216308e-04  4.195477e-04  4.135378e-04  4.129701e-04  4.077862e-04
## [256]  4.061885e-04  3.972653e-04  3.906004e-04  3.862412e-04  3.836655e-04
## [261]  3.802945e-04  3.760241e-04  3.728518e-04  3.647448e-04  3.637860e-04
## [266]  3.624120e-04  3.551893e-04  3.519662e-04  3.478858e-04  3.423929e-04
## [271]  3.397890e-04  3.372576e-04  3.301917e-04  3.280967e-04  3.249449e-04
## [276]  3.236946e-04  3.189856e-04  3.166193e-04  3.089481e-04  3.046247e-04
## [281]  3.030005e-04  3.018005e-04  3.012218e-04  2.930320e-04  2.918016e-04
## [286]  2.891901e-04  2.837885e-04  2.811630e-04  2.768542e-04  2.744377e-04
## [291]  2.699204e-04  2.665156e-04  2.620827e-04  2.593953e-04  2.579130e-04
## [296]  2.518968e-04  2.488487e-04  2.453290e-04  2.419554e-04  2.376325e-04
## [301]  2.357410e-04  2.338942e-04  2.272621e-04  2.245786e-04  2.183855e-04
## [306]  2.164432e-04  2.115597e-04  2.113121e-04  2.056919e-04  2.040437e-04
## [311]  2.027865e-04  2.004940e-04  1.986627e-04  1.957481e-04  1.926406e-04
## [316]  1.882846e-04  1.872123e-04  1.822859e-04  1.795174e-04  1.746086e-04
## [321]  1.734957e-04  1.714620e-04  1.685460e-04  1.651738e-04  1.616421e-04
## [326]  1.577175e-04  1.550198e-04  1.544488e-04  1.532046e-04  1.489849e-04
## [331]  1.445931e-04  1.434212e-04  1.408367e-04  1.386853e-04  1.378187e-04
## [336]  1.334880e-04  1.304580e-04  1.279531e-04  1.272370e-04  1.215714e-04
## [341]  1.172695e-04  1.160320e-04  1.144858e-04  1.141234e-04  1.100192e-04
## [346]  1.077767e-04  1.046630e-04  1.002115e-04  9.876728e-05  9.579260e-05
## [351]  9.210136e-05  8.811261e-05  8.671104e-05  8.374312e-05  8.288510e-05
## [356]  8.056270e-05  7.775032e-05  7.615514e-05  7.584420e-05  7.277204e-05
## [361]  7.185246e-05  6.802301e-05  6.426648e-05  6.305503e-05  6.095492e-05
## [366]  5.943770e-05  5.546325e-05  5.401489e-05  5.348083e-05  4.889010e-05
## [371]  4.794031e-05  4.641037e-05  4.281561e-05  3.971127e-05  3.814856e-05
## [376]  3.584652e-05  3.559515e-05  3.061955e-05  2.993955e-05  2.695095e-05
## [381]  2.477291e-05  2.449526e-05  2.188632e-05  2.073269e-05  1.915050e-05
## [386]  1.517452e-05  1.325450e-05  1.257215e-05  1.175821e-05  8.714046e-06
## [391]  6.633354e-06  4.210821e-06  1.449036e-06 -1.731158e-17 -7.670623e-07
## [396] -2.140631e-06 -4.351862e-06 -6.191374e-06 -7.439289e-06 -9.184679e-06
## [401] -1.198049e-05 -1.353064e-05 -1.415536e-05 -1.652300e-05 -1.723636e-05
## [406] -1.812887e-05 -1.910567e-05 -2.000013e-05 -2.514817e-05 -2.755679e-05
## [411] -2.982977e-05 -3.207926e-05 -3.349379e-05 -3.591842e-05 -3.640661e-05
## [416] -3.662875e-05 -3.897209e-05 -3.970581e-05 -4.226908e-05 -4.352428e-05
## [421] -4.540872e-05 -4.641150e-05 -4.916225e-05 -5.093794e-05 -5.338964e-05
## [426] -5.488062e-05 -5.518233e-05 -5.670434e-05 -5.826558e-05 -6.141662e-05
## [431] -6.225227e-05 -6.387754e-05 -6.591279e-05 -6.645496e-05 -6.898855e-05
## [436] -7.148055e-05 -7.209962e-05 -7.349996e-05 -7.448065e-05 -7.604767e-05
## [441] -7.621573e-05 -7.792249e-05 -8.080872e-05 -8.395162e-05 -8.443471e-05
## [446] -8.652501e-05 -8.789373e-05 -8.912552e-05 -9.033894e-05 -9.150096e-05
## [451] -9.326826e-05 -9.544376e-05 -9.591623e-05 -9.705363e-05 -9.933619e-05
## [456] -1.003560e-04 -1.011467e-04 -1.015517e-04 -1.052177e-04 -1.068305e-04
## [461] -1.073337e-04 -1.086136e-04 -1.092110e-04 -1.116826e-04 -1.128922e-04
## [466] -1.145188e-04 -1.177508e-04 -1.182268e-04 -1.188420e-04 -1.210009e-04
## [471] -1.212389e-04 -1.226489e-04 -1.240949e-04 -1.246841e-04 -1.274300e-04
## [476] -1.281634e-04 -1.305374e-04 -1.314300e-04 -1.328645e-04 -1.336003e-04
## [481] -1.360338e-04 -1.366718e-04 -1.382849e-04 -1.395493e-04 -1.400993e-04
## [486] -1.414987e-04 -1.422691e-04 -1.437184e-04 -1.449773e-04 -1.459808e-04
## [491] -1.476558e-04 -1.482265e-04 -1.505624e-04 -1.528561e-04 -1.541011e-04
## [496] -1.551525e-04 -1.557908e-04 -1.580862e-04 -1.599142e-04 -1.602860e-04
## [501] -1.611562e-04 -1.615163e-04 -1.629027e-04 -1.650273e-04 -1.654091e-04
## [506] -1.670133e-04 -1.686964e-04 -1.699660e-04 -1.702506e-04 -1.725799e-04
## [511] -1.730880e-04 -1.738738e-04 -1.763154e-04 -1.771231e-04 -1.778245e-04
## [516] -1.786411e-04 -1.807572e-04 -1.811836e-04 -1.825610e-04 -1.837709e-04
## [521] -1.854274e-04 -1.867762e-04 -1.871517e-04 -1.886175e-04 -1.886847e-04
## [526] -1.908429e-04 -1.912135e-04 -1.933125e-04 -1.951670e-04 -1.960588e-04
## [531] -1.971499e-04 -1.973527e-04 -1.994235e-04 -2.001224e-04 -2.013066e-04
## [536] -2.015026e-04 -2.028494e-04 -2.036928e-04 -2.052210e-04 -2.061049e-04
## [541] -2.068377e-04 -2.083977e-04 -2.089547e-04 -2.096927e-04 -2.120559e-04
## [546] -2.123273e-04 -2.134616e-04 -2.144144e-04 -2.160530e-04 -2.168725e-04
## [551] -2.180592e-04 -2.185919e-04 -2.196377e-04 -2.198309e-04 -2.218373e-04
## [556] -2.223349e-04 -2.230948e-04 -2.235989e-04 -2.249880e-04 -2.268386e-04
## [561] -2.272827e-04 -2.286440e-04 -2.294137e-04 -2.310458e-04 -2.316744e-04
## [566] -2.327895e-04 -2.338765e-04 -2.349985e-04 -2.353619e-04 -2.372273e-04
## [571] -2.376466e-04 -2.386134e-04 -2.395514e-04 -2.406710e-04 -2.424389e-04
## [576] -2.433458e-04 -2.440767e-04 -2.460112e-04 -2.466953e-04 -2.498171e-04
## [581] -2.502681e-04 -2.508957e-04 -2.520429e-04 -2.526101e-04 -2.528243e-04
## [586] -2.542139e-04 -2.552695e-04 -2.565946e-04 -2.566646e-04 -2.574295e-04
## [591] -2.587749e-04 -2.595611e-04 -2.604548e-04 -2.614050e-04 -2.619235e-04
## [596] -2.638831e-04 -2.643064e-04 -2.651676e-04 -2.661152e-04 -2.670238e-04
## [601] -2.686876e-04 -2.692321e-04 -2.704510e-04 -2.712777e-04 -2.725222e-04
## [606] -2.744067e-04 -2.747005e-04 -2.761122e-04 -2.764416e-04 -2.778088e-04
## [611] -2.792281e-04 -2.804131e-04 -2.813199e-04 -2.825029e-04 -2.832165e-04
## [616] -2.846074e-04 -2.849679e-04 -2.854315e-04 -2.866257e-04 -2.882886e-04
## [621] -2.886796e-04 -2.897676e-04 -2.909176e-04 -2.916454e-04 -2.936315e-04
## [626] -2.945988e-04 -2.956467e-04 -2.976709e-04 -2.977750e-04 -2.993418e-04
## [631] -3.012977e-04 -3.017533e-04 -3.020923e-04 -3.026205e-04 -3.034785e-04
## [636] -3.053155e-04 -3.058750e-04 -3.078013e-04 -3.084850e-04 -3.095046e-04
## [641] -3.100037e-04 -3.112952e-04 -3.117480e-04 -3.137446e-04 -3.145800e-04
## [646] -3.151136e-04 -3.156842e-04 -3.164964e-04 -3.170957e-04 -3.189203e-04
## [651] -3.194713e-04 -3.209668e-04 -3.222476e-04 -3.233258e-04 -3.239370e-04
## [656] -3.243310e-04 -3.250869e-04 -3.258826e-04 -3.265237e-04 -3.280450e-04
## [661] -3.293588e-04 -3.312182e-04 -3.317732e-04 -3.330475e-04 -3.336940e-04
## [666] -3.349342e-04 -3.359019e-04 -3.378386e-04 -3.386272e-04 -3.390984e-04
## [671] -3.402191e-04 -3.409045e-04 -3.432037e-04 -3.443328e-04 -3.448570e-04
## [676] -3.452660e-04 -3.464459e-04 -3.479980e-04 -3.490821e-04 -3.507496e-04
## [681] -3.510810e-04 -3.517997e-04 -3.527970e-04 -3.544011e-04 -3.556359e-04
## [686] -3.565363e-04 -3.583365e-04 -3.586972e-04 -3.595924e-04 -3.599798e-04
## [691] -3.622402e-04 -3.627692e-04 -3.646006e-04 -3.655243e-04 -3.663451e-04
## [696] -3.671750e-04 -3.683522e-04 -3.690541e-04 -3.697686e-04 -3.719974e-04
## [701] -3.721188e-04 -3.734743e-04 -3.738331e-04 -3.749721e-04 -3.757344e-04
## [706] -3.789264e-04 -3.804052e-04 -3.809892e-04 -3.825105e-04 -3.828982e-04
## [711] -3.835744e-04 -3.845504e-04 -3.865762e-04 -3.877561e-04 -3.889381e-04
## [716] -3.897066e-04 -3.909488e-04 -3.921423e-04 -3.927068e-04 -3.934824e-04
## [721] -3.954268e-04 -3.970467e-04 -3.981705e-04 -3.993141e-04 -3.993995e-04
## [726] -4.007296e-04 -4.021536e-04 -4.025620e-04 -4.041933e-04 -4.050633e-04
## [731] -4.062114e-04 -4.079917e-04 -4.096342e-04 -4.106038e-04 -4.117160e-04
## [736] -4.131668e-04 -4.132369e-04 -4.150944e-04 -4.163866e-04 -4.177085e-04
## [741] -4.197068e-04 -4.204602e-04 -4.218410e-04 -4.243821e-04 -4.258981e-04
## [746] -4.267853e-04 -4.281205e-04 -4.296091e-04 -4.311993e-04 -4.319420e-04
## [751] -4.326854e-04 -4.336817e-04 -4.350019e-04 -4.372709e-04 -4.383052e-04
## [756] -4.395029e-04 -4.410275e-04 -4.426398e-04 -4.453689e-04 -4.463609e-04
## [761] -4.480148e-04 -4.484461e-04 -4.511211e-04 -4.534126e-04 -4.542898e-04
## [766] -4.554118e-04 -4.560000e-04 -4.580564e-04 -4.587725e-04 -4.617543e-04
## [771] -4.619058e-04 -4.632325e-04 -4.655799e-04 -4.671787e-04 -4.678117e-04
## [776] -4.697639e-04 -4.728132e-04 -4.739260e-04 -4.767137e-04 -4.772619e-04
## [781] -4.786366e-04 -4.811534e-04 -4.823889e-04 -4.863708e-04 -4.870262e-04
## [786] -4.881246e-04 -4.889375e-04 -4.929849e-04 -4.942186e-04 -4.957385e-04
## [791] -4.987134e-04 -4.990720e-04 -5.023196e-04 -5.038940e-04 -5.060840e-04
## [796] -5.067679e-04 -5.096620e-04 -5.113650e-04 -5.129942e-04 -5.180026e-04
## [801] -5.202189e-04 -5.204010e-04 -5.237129e-04 -5.247244e-04 -5.254168e-04
## [806] -5.284045e-04 -5.328674e-04 -5.366168e-04 -5.374284e-04 -5.391002e-04
## [811] -5.415445e-04 -5.428483e-04 -5.493033e-04 -5.555837e-04 -5.596516e-04
## [816] -5.622023e-04 -5.650352e-04 -5.672778e-04 -5.673452e-04 -5.733997e-04
## [821] -5.750579e-04 -5.773863e-04 -5.800495e-04 -5.850040e-04 -5.910198e-04
## [826] -5.936994e-04 -6.013483e-04 -6.030985e-04 -6.053062e-04 -6.121428e-04
## [831] -6.174978e-04 -6.232269e-04 -6.242243e-04 -6.297121e-04 -6.425681e-04
## [836] -6.436628e-04 -6.534730e-04 -6.582685e-04 -6.633464e-04 -6.649812e-04
## [841] -6.747351e-04 -6.775370e-04 -7.000759e-04 -7.068384e-04 -7.193204e-04
## [846] -7.247106e-04 -7.336333e-04 -7.408725e-04 -7.537957e-04 -7.791541e-04
## [851] -7.856518e-04 -8.187402e-04 -8.280195e-04 -8.349727e-04 -8.460070e-04
## [856] -8.778223e-04 -9.068877e-04 -9.134206e-04 -9.746723e-04 -1.037038e-03
## [861] -1.128185e-03 -1.424785e-03 -2.255084e-03
evaluate_consistency_metrics(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores,)
## $trustworthiness
## [1] 0.6060587
## 
## $continuity
## [1] 0.8399284
## 
## $mantel_statistic
## [1] 0.3895514
## 
## $mantel_p
## [1] 0.001
cjtt_u_test(dist_bray_filt, age_filt, var_method = "analytic")
## $U_statistic
## [1] 0.05416545
## 
## $variance
## [1] 0.0005144019
## 
## $z_score
## [1] 2.388202
## 
## $p_value
## [1] 0.01693104
## 
## $method
## [1] "analytic"
# cjtt_u_test(dist_bray_filt, age_filt, var_method = "jackknife") Take too long
# cjtt_u_test(dist_bray_filt, age_filt, var_method = "bootstrap")
# cjtt_u_test(dist_bray_filt, age_filt, permutation = T)
gco_decomposition(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
##     consistency_score outlier        class
## 1                 0.2   FALSE Intermediate
## 2                 0.0   FALSE       C-type
## 3                 0.0   FALSE       C-type
## 4                 0.1   FALSE       C-type
## 5                 0.1   FALSE       C-type
## 6                 0.2   FALSE Intermediate
## 7                 0.2    TRUE       O-type
## 8                 0.1   FALSE       C-type
## 9                 0.1   FALSE       C-type
## 10                0.1   FALSE       C-type
## 11                0.1   FALSE       C-type
## 12                0.0   FALSE       C-type
## 13                0.0   FALSE       C-type
## 14                0.1   FALSE       C-type
## 15                0.1   FALSE       C-type
## 16                0.0   FALSE       C-type
## 17                0.0   FALSE       C-type
## 18                0.0   FALSE       C-type
## 19                0.0   FALSE       C-type
## 20                0.0   FALSE       C-type
## 21                0.1   FALSE       C-type
## 22                0.0   FALSE       C-type
## 23                0.0   FALSE       C-type
## 24                0.0   FALSE       C-type
## 25                0.0   FALSE       C-type
## 26                0.1   FALSE       C-type
## 27                0.0   FALSE       C-type
## 28                0.0    TRUE       O-type
## 29                0.0   FALSE       C-type
## 30                0.0   FALSE       C-type
## 31                0.0   FALSE       C-type
## 32                0.1   FALSE       C-type
## 33                0.1   FALSE       C-type
## 34                0.0   FALSE       C-type
## 35                0.1   FALSE       C-type
## 36                0.0   FALSE       C-type
## 37                0.0   FALSE       C-type
## 38                0.1   FALSE       C-type
## 39                0.0   FALSE       C-type
## 40                0.0   FALSE       C-type
## 41                0.0   FALSE       C-type
## 42                0.0   FALSE       C-type
## 43                0.0   FALSE       C-type
## 44                0.0   FALSE       C-type
## 45                0.3   FALSE Intermediate
## 46                0.0   FALSE       C-type
## 47                0.1   FALSE       C-type
## 48                0.2   FALSE Intermediate
## 49                0.0   FALSE       C-type
## 50                0.1   FALSE       C-type
## 51                0.0   FALSE       C-type
## 52                0.1   FALSE       C-type
## 53                0.0   FALSE       C-type
## 54                0.1   FALSE       C-type
## 55                0.1   FALSE       C-type
## 56                0.0   FALSE       C-type
## 57                0.0   FALSE       C-type
## 58                0.0   FALSE       C-type
## 59                0.2   FALSE Intermediate
## 60                0.2   FALSE Intermediate
## 61                0.1   FALSE       C-type
## 62                0.1   FALSE       C-type
## 63                0.0   FALSE       C-type
## 64                0.0   FALSE       C-type
## 65                0.0   FALSE       C-type
## 66                0.0   FALSE       C-type
## 67                0.1   FALSE       C-type
## 68                0.0   FALSE       C-type
## 69                0.0   FALSE       C-type
## 70                0.0   FALSE       C-type
## 71                0.0   FALSE       C-type
## 72                0.0   FALSE       C-type
## 73                0.0   FALSE       C-type
## 74                0.0   FALSE       C-type
## 75                0.0   FALSE       C-type
## 76                0.0   FALSE       C-type
## 77                0.0   FALSE       C-type
## 78                0.2   FALSE Intermediate
## 79                0.0    TRUE       O-type
## 80                0.0    TRUE       O-type
## 81                0.0   FALSE       C-type
## 82                0.1   FALSE       C-type
## 83                0.1   FALSE       C-type
## 84                0.0   FALSE       C-type
## 85                0.0   FALSE       C-type
## 86                0.0   FALSE       C-type
## 87                0.0    TRUE       O-type
## 88                0.0   FALSE       C-type
## 89                0.2    TRUE       O-type
## 90                0.0   FALSE       C-type
## 91                0.0   FALSE       C-type
## 92                0.0   FALSE       C-type
## 93                0.0   FALSE       C-type
## 94                0.0   FALSE       C-type
## 95                0.1   FALSE       C-type
## 96                0.0   FALSE       C-type
## 97                0.1   FALSE       C-type
## 98                0.0   FALSE       C-type
## 99                0.1   FALSE       C-type
## 100               0.0   FALSE       C-type
## 101               0.1   FALSE       C-type
## 102               0.0   FALSE       C-type
## 103               0.2   FALSE Intermediate
## 104               0.1   FALSE       C-type
## 105               0.0   FALSE       C-type
## 106               0.2   FALSE Intermediate
## 107               0.0   FALSE       C-type
## 108               0.2   FALSE Intermediate
## 109               0.1   FALSE       C-type
## 110               0.0   FALSE       C-type
## 111               0.0   FALSE       C-type
## 112               0.0   FALSE       C-type
## 113               0.0   FALSE       C-type
## 114               0.0   FALSE       C-type
## 115               0.0   FALSE       C-type
## 116               0.0   FALSE       C-type
## 117               0.1   FALSE       C-type
## 118               0.0   FALSE       C-type
## 119               0.0   FALSE       C-type
## 120               0.3    TRUE       O-type
## 121               0.1   FALSE       C-type
## 122               0.0   FALSE       C-type
## 123               0.1   FALSE       C-type
## 124               0.0   FALSE       C-type
## 125               0.1   FALSE       C-type
## 126               0.0    TRUE       O-type
## 127               0.0   FALSE       C-type
## 128               0.0   FALSE       C-type
## 129               0.0   FALSE       C-type
## 130               0.0   FALSE       C-type
## 131               0.1   FALSE       C-type
## 132               0.0    TRUE       O-type
## 133               0.0   FALSE       C-type
## 134               0.2   FALSE Intermediate
## 135               0.0   FALSE       C-type
## 136               0.0   FALSE       C-type
## 137               0.0   FALSE       C-type
## 138               0.1    TRUE       O-type
## 139               0.0   FALSE       C-type
## 140               0.1   FALSE       C-type
## 141               0.0   FALSE       C-type
## 142               0.0   FALSE       C-type
## 143               0.0   FALSE       C-type
## 144               0.0   FALSE       C-type
## 145               0.0   FALSE       C-type
## 146               0.2   FALSE Intermediate
## 147               0.0   FALSE       C-type
## 148               0.0   FALSE       C-type
## 149               0.0   FALSE       C-type
## 150               0.2   FALSE Intermediate
## 151               0.0   FALSE       C-type
## 152               0.1   FALSE       C-type
## 153               0.0   FALSE       C-type
## 154               0.0   FALSE       C-type
## 155               0.0   FALSE       C-type
## 156               0.0   FALSE       C-type
## 157               0.1   FALSE       C-type
## 158               0.0   FALSE       C-type
## 159               0.1   FALSE       C-type
## 160               0.0   FALSE       C-type
## 161               0.0   FALSE       C-type
## 162               0.0   FALSE       C-type
## 163               0.0   FALSE       C-type
## 164               0.0   FALSE       C-type
## 165               0.0   FALSE       C-type
## 166               0.1   FALSE       C-type
## 167               0.0   FALSE       C-type
## 168               0.2   FALSE Intermediate
## 169               0.0   FALSE       C-type
## 170               0.0   FALSE       C-type
## 171               0.0   FALSE       C-type
## 172               0.0   FALSE       C-type
## 173               0.0   FALSE       C-type
## 174               0.0   FALSE       C-type
## 175               0.1   FALSE       C-type
## 176               0.0   FALSE       C-type
## 177               0.2   FALSE Intermediate
## 178               0.0   FALSE       C-type
## 179               0.2    TRUE       O-type
## 180               0.1   FALSE       C-type
## 181               0.0   FALSE       C-type
## 182               0.1   FALSE       C-type
## 183               0.0   FALSE       C-type
## 184               0.0   FALSE       C-type
## 185               0.1   FALSE       C-type
## 186               0.0   FALSE       C-type
## 187               0.1   FALSE       C-type
## 188               0.1   FALSE       C-type
## 189               0.0   FALSE       C-type
## 190               0.1   FALSE       C-type
## 191               0.0   FALSE       C-type
## 192               0.0   FALSE       C-type
## 193               0.1   FALSE       C-type
## 194               0.1   FALSE       C-type
## 195               0.1   FALSE       C-type
## 196               0.0   FALSE       C-type
## 197               0.0   FALSE       C-type
## 198               0.6    TRUE       O-type
## 199               0.0   FALSE       C-type
## 200               0.1   FALSE       C-type
## 201               0.0   FALSE       C-type
## 202               0.1   FALSE       C-type
## 203               0.3    TRUE       O-type
## 204               0.1   FALSE       C-type
## 205               0.0   FALSE       C-type
## 206               0.1   FALSE       C-type
## 207               0.0   FALSE       C-type
## 208               0.1   FALSE       C-type
## 209               0.0   FALSE       C-type
## 210               0.1   FALSE       C-type
## 211               0.1   FALSE       C-type
## 212               0.1   FALSE       C-type
## 213               0.0   FALSE       C-type
## 214               0.1   FALSE       C-type
## 215               0.0   FALSE       C-type
## 216               0.2   FALSE Intermediate
## 217               0.1   FALSE       C-type
## 218               0.0   FALSE       C-type
## 219               0.0   FALSE       C-type
## 220               0.2   FALSE Intermediate
## 221               0.1   FALSE       C-type
## 222               0.1   FALSE       C-type
## 223               0.0   FALSE       C-type
## 224               0.2    TRUE       O-type
## 225               0.1   FALSE       C-type
## 226               0.1    TRUE       O-type
## 227               0.0   FALSE       C-type
## 228               0.0   FALSE       C-type
## 229               0.1   FALSE       C-type
## 230               0.1   FALSE       C-type
## 231               0.2   FALSE Intermediate
## 232               0.0   FALSE       C-type
## 233               0.0   FALSE       C-type
## 234               0.0   FALSE       C-type
## 235               0.1   FALSE       C-type
## 236               0.0   FALSE       C-type
## 237               0.0   FALSE       C-type
## 238               0.0   FALSE       C-type
## 239               0.1   FALSE       C-type
## 240               0.0   FALSE       C-type
## 241               0.1   FALSE       C-type
## 242               0.0   FALSE       C-type
## 243               0.1   FALSE       C-type
## 244               0.1   FALSE       C-type
## 245               0.0   FALSE       C-type
## 246               0.0   FALSE       C-type
## 247               0.1   FALSE       C-type
## 248               0.3   FALSE Intermediate
## 249               0.0    TRUE       O-type
## 250               0.1   FALSE       C-type
## 251               0.0   FALSE       C-type
## 252               0.0   FALSE       C-type
## 253               0.0   FALSE       C-type
## 254               0.2   FALSE Intermediate
## 255               0.0   FALSE       C-type
## 256               0.0   FALSE       C-type
## 257               0.1   FALSE       C-type
## 258               0.1   FALSE       C-type
## 259               0.2   FALSE Intermediate
## 260               0.0   FALSE       C-type
## 261               0.2   FALSE Intermediate
## 262               0.0   FALSE       C-type
## 263               0.1   FALSE       C-type
## 264               0.1   FALSE       C-type
## 265               0.0   FALSE       C-type
## 266               0.1   FALSE       C-type
## 267               0.0   FALSE       C-type
## 268               0.1   FALSE       C-type
## 269               0.0   FALSE       C-type
## 270               0.1   FALSE       C-type
## 271               0.0   FALSE       C-type
## 272               0.0   FALSE       C-type
## 273               0.1   FALSE       C-type
## 274               0.0   FALSE       C-type
## 275               0.1    TRUE       O-type
## 276               0.0   FALSE       C-type
## 277               0.2   FALSE Intermediate
## 278               0.0   FALSE       C-type
## 279               0.1   FALSE       C-type
## 280               0.2   FALSE Intermediate
## 281               0.0   FALSE       C-type
## 282               0.0   FALSE       C-type
## 283               0.0   FALSE       C-type
## 284               0.0   FALSE       C-type
## 285               0.0   FALSE       C-type
## 286               0.2   FALSE Intermediate
## 287               0.3   FALSE Intermediate
## 288               0.0   FALSE       C-type
## 289               0.2   FALSE Intermediate
## 290               0.2   FALSE Intermediate
## 291               0.1   FALSE       C-type
## 292               0.0   FALSE       C-type
## 293               0.1   FALSE       C-type
## 294               0.1   FALSE       C-type
## 295               0.1   FALSE       C-type
## 296               0.0   FALSE       C-type
## 297               0.0   FALSE       C-type
## 298               0.0   FALSE       C-type
## 299               0.0   FALSE       C-type
## 300               0.0   FALSE       C-type
## 301               0.0   FALSE       C-type
## 302               0.2   FALSE Intermediate
## 303               0.0   FALSE       C-type
## 304               0.0   FALSE       C-type
## 305               0.1   FALSE       C-type
## 306               0.1   FALSE       C-type
## 307               0.0   FALSE       C-type
## 308               0.1    TRUE       O-type
## 309               0.0   FALSE       C-type
## 310               0.0   FALSE       C-type
## 311               0.1   FALSE       C-type
## 312               0.0   FALSE       C-type
## 313               0.0   FALSE       C-type
## 314               0.0   FALSE       C-type
## 315               0.1   FALSE       C-type
## 316               0.1   FALSE       C-type
## 317               0.0   FALSE       C-type
## 318               0.0   FALSE       C-type
## 319               0.3   FALSE Intermediate
## 320               0.1   FALSE       C-type
## 321               0.0   FALSE       C-type
## 322               0.0   FALSE       C-type
## 323               0.0   FALSE       C-type
## 324               0.0   FALSE       C-type
## 325               0.0   FALSE       C-type
## 326               0.1   FALSE       C-type
## 327               0.1   FALSE       C-type
## 328               0.0   FALSE       C-type
## 329               0.2   FALSE Intermediate
## 330               0.1   FALSE       C-type
## 331               0.0   FALSE       C-type
## 332               0.1   FALSE       C-type
## 333               0.1    TRUE       O-type
## 334               0.2   FALSE Intermediate
## 335               0.2   FALSE Intermediate
## 336               0.0   FALSE       C-type
## 337               0.2   FALSE Intermediate
## 338               0.0   FALSE       C-type
## 339               0.2   FALSE Intermediate
## 340               0.1   FALSE       C-type
## 341               0.1   FALSE       C-type
## 342               0.0   FALSE       C-type
## 343               0.0   FALSE       C-type
## 344               0.0   FALSE       C-type
## 345               0.0   FALSE       C-type
## 346               0.1   FALSE       C-type
## 347               0.0   FALSE       C-type
## 348               0.0   FALSE       C-type
## 349               0.0   FALSE       C-type
## 350               0.0   FALSE       C-type
## 351               0.0   FALSE       C-type
## 352               0.0   FALSE       C-type
## 353               0.0   FALSE       C-type
## 354               0.0   FALSE       C-type
## 355               0.0   FALSE       C-type
## 356               0.0   FALSE       C-type
## 357               0.0   FALSE       C-type
## 358               0.0   FALSE       C-type
## 359               0.1   FALSE       C-type
## 360               0.1   FALSE       C-type
## 361               0.0    TRUE       O-type
## 362               0.0    TRUE       O-type
## 363               0.1   FALSE       C-type
## 364               0.0   FALSE       C-type
## 365               0.1   FALSE       C-type
## 366               0.0   FALSE       C-type
## 367               0.2   FALSE Intermediate
## 368               0.0   FALSE       C-type
## 369               0.0   FALSE       C-type
## 370               0.0   FALSE       C-type
## 371               0.1   FALSE       C-type
## 372               0.1   FALSE       C-type
## 373               0.0   FALSE       C-type
## 374               0.0   FALSE       C-type
## 375               0.1    TRUE       O-type
## 376               0.1   FALSE       C-type
## 377               0.0   FALSE       C-type
## 378               0.2   FALSE Intermediate
## 379               0.0   FALSE       C-type
## 380               0.0   FALSE       C-type
## 381               0.0   FALSE       C-type
## 382               0.1    TRUE       O-type
## 383               0.0   FALSE       C-type
## 384               0.1   FALSE       C-type
## 385               0.0   FALSE       C-type
## 386               0.0    TRUE       O-type
## 387               0.0   FALSE       C-type
## 388               0.2    TRUE       O-type
## 389               0.1   FALSE       C-type
## 390               0.0   FALSE       C-type
## 391               0.0   FALSE       C-type
## 392               0.0   FALSE       C-type
## 393               0.0   FALSE       C-type
## 394               0.0   FALSE       C-type
## 395               0.0   FALSE       C-type
## 396               0.3    TRUE       O-type
## 397               0.0   FALSE       C-type
## 398               0.0   FALSE       C-type
## 399               0.0   FALSE       C-type
## 400               0.0   FALSE       C-type
## 401               0.0   FALSE       C-type
## 402               0.0   FALSE       C-type
## 403               0.0   FALSE       C-type
## 404               0.1   FALSE       C-type
## 405               0.0   FALSE       C-type
## 406               0.2   FALSE Intermediate
## 407               0.1   FALSE       C-type
## 408               0.0   FALSE       C-type
## 409               0.0   FALSE       C-type
## 410               0.1   FALSE       C-type
## 411               0.0   FALSE       C-type
## 412               0.0   FALSE       C-type
## 413               0.1   FALSE       C-type
## 414               0.2   FALSE Intermediate
## 415               0.0   FALSE       C-type
## 416               0.0   FALSE       C-type
## 417               0.5    TRUE       O-type
## 418               0.1   FALSE       C-type
## 419               0.1   FALSE       C-type
## 420               0.0   FALSE       C-type
## 421               0.4    TRUE       O-type
## 422               0.2   FALSE Intermediate
## 423               0.0   FALSE       C-type
## 424               0.0   FALSE       C-type
## 425               0.2   FALSE Intermediate
## 426               0.0   FALSE       C-type
## 427               0.1   FALSE       C-type
## 428               0.2   FALSE Intermediate
## 429               0.0   FALSE       C-type
## 430               0.1   FALSE       C-type
## 431               0.0   FALSE       C-type
## 432               0.2   FALSE Intermediate
## 433               0.1   FALSE       C-type
## 434               0.1   FALSE       C-type
## 435               0.2   FALSE Intermediate
## 436               0.0   FALSE       C-type
## 437               0.0   FALSE       C-type
## 438               0.2   FALSE Intermediate
## 439               0.0   FALSE       C-type
## 440               0.0   FALSE       C-type
## 441               0.0   FALSE       C-type
## 442               0.0   FALSE       C-type
## 443               0.0   FALSE       C-type
## 444               0.2   FALSE Intermediate
## 445               0.0   FALSE       C-type
## 446               0.0    TRUE       O-type
## 447               0.1   FALSE       C-type
## 448               0.2   FALSE Intermediate
## 449               0.1   FALSE       C-type
## 450               0.1   FALSE       C-type
## 451               0.0   FALSE       C-type
## 452               0.1   FALSE       C-type
## 453               0.2   FALSE Intermediate
## 454               0.0   FALSE       C-type
## 455               0.1   FALSE       C-type
## 456               0.0   FALSE       C-type
## 457               0.0   FALSE       C-type
## 458               0.3    TRUE       O-type
## 459               0.0   FALSE       C-type
## 460               0.2   FALSE Intermediate
## 461               0.2   FALSE Intermediate
## 462               0.0   FALSE       C-type
## 463               0.1   FALSE       C-type
## 464               0.1   FALSE       C-type
## 465               0.0   FALSE       C-type
## 466               0.1   FALSE       C-type
## 467               0.0   FALSE       C-type
## 468               0.0   FALSE       C-type
## 469               0.1    TRUE       O-type
## 470               0.1   FALSE       C-type
## 471               0.0   FALSE       C-type
## 472               0.0   FALSE       C-type
## 473               0.0   FALSE       C-type
## 474               0.0   FALSE       C-type
## 475               0.0    TRUE       O-type
## 476               0.0   FALSE       C-type
## 477               0.1   FALSE       C-type
## 478               0.0   FALSE       C-type
## 479               0.2   FALSE Intermediate
## 480               0.0    TRUE       O-type
## 481               0.1   FALSE       C-type
## 482               0.0   FALSE       C-type
## 483               0.0   FALSE       C-type
## 484               0.2    TRUE       O-type
## 485               0.0   FALSE       C-type
## 486               0.0   FALSE       C-type
## 487               0.0   FALSE       C-type
## 488               0.0   FALSE       C-type
## 489               0.1   FALSE       C-type
## 490               0.0   FALSE       C-type
## 491               0.2   FALSE Intermediate
## 492               0.0   FALSE       C-type
## 493               0.0   FALSE       C-type
## 494               0.1   FALSE       C-type
## 495               0.1   FALSE       C-type
## 496               0.1   FALSE       C-type
## 497               0.0    TRUE       O-type
## 498               0.0   FALSE       C-type
## 499               0.0   FALSE       C-type
## 500               0.1   FALSE       C-type
## 501               0.0    TRUE       O-type
## 502               0.0   FALSE       C-type
## 503               0.0   FALSE       C-type
## 504               0.2   FALSE Intermediate
## 505               0.1   FALSE       C-type
## 506               0.1   FALSE       C-type
## 507               0.0   FALSE       C-type
## 508               0.0   FALSE       C-type
## 509               0.0   FALSE       C-type
## 510               0.1   FALSE       C-type
## 511               0.0   FALSE       C-type
## 512               0.0   FALSE       C-type
## 513               0.1   FALSE       C-type
## 514               0.1   FALSE       C-type
## 515               0.1   FALSE       C-type
## 516               0.1   FALSE       C-type
## 517               0.0   FALSE       C-type
## 518               0.1   FALSE       C-type
## 519               0.2   FALSE Intermediate
## 520               0.0   FALSE       C-type
## 521               0.1   FALSE       C-type
## 522               0.4    TRUE       O-type
## 523               0.1   FALSE       C-type
## 524               0.0   FALSE       C-type
## 525               0.2    TRUE       O-type
## 526               0.0   FALSE       C-type
## 527               0.0   FALSE       C-type
## 528               0.0   FALSE       C-type
## 529               0.0   FALSE       C-type
## 530               0.1   FALSE       C-type
## 531               0.0   FALSE       C-type
## 532               0.0   FALSE       C-type
## 533               0.0   FALSE       C-type
## 534               0.1   FALSE       C-type
## 535               0.1    TRUE       O-type
## 536               0.0   FALSE       C-type
## 537               0.0   FALSE       C-type
## 538               0.0    TRUE       O-type
## 539               0.0   FALSE       C-type
## 540               0.0   FALSE       C-type
## 541               0.0   FALSE       C-type
## 542               0.1   FALSE       C-type
## 543               0.0   FALSE       C-type
## 544               0.1   FALSE       C-type
## 545               0.0   FALSE       C-type
## 546               0.0   FALSE       C-type
## 547               0.3   FALSE Intermediate
## 548               0.0   FALSE       C-type
## 549               0.1   FALSE       C-type
## 550               0.1   FALSE       C-type
## 551               0.1   FALSE       C-type
## 552               0.1    TRUE       O-type
## 553               0.0   FALSE       C-type
## 554               0.0   FALSE       C-type
## 555               0.0    TRUE       O-type
## 556               0.0   FALSE       C-type
## 557               0.0   FALSE       C-type
## 558               0.0   FALSE       C-type
## 559               0.0   FALSE       C-type
## 560               0.1    TRUE       O-type
## 561               0.0   FALSE       C-type
## 562               0.0   FALSE       C-type
## 563               0.0   FALSE       C-type
## 564               0.1   FALSE       C-type
## 565               0.0   FALSE       C-type
## 566               0.0   FALSE       C-type
## 567               0.1   FALSE       C-type
## 568               0.3   FALSE Intermediate
## 569               0.0   FALSE       C-type
## 570               0.0   FALSE       C-type
## 571               0.2   FALSE Intermediate
## 572               0.0   FALSE       C-type
## 573               0.1   FALSE       C-type
## 574               0.0    TRUE       O-type
## 575               0.1   FALSE       C-type
## 576               0.1   FALSE       C-type
## 577               0.0   FALSE       C-type
## 578               0.4    TRUE       O-type
## 579               0.1   FALSE       C-type
## 580               0.0   FALSE       C-type
## 581               0.0   FALSE       C-type
## 582               0.0   FALSE       C-type
## 583               0.1   FALSE       C-type
## 584               0.0   FALSE       C-type
## 585               0.1   FALSE       C-type
## 586               0.0   FALSE       C-type
## 587               0.5    TRUE       O-type
## 588               0.2    TRUE       O-type
## 589               0.1    TRUE       O-type
## 590               0.1   FALSE       C-type
## 591               0.0    TRUE       O-type
## 592               0.0   FALSE       C-type
## 593               0.2   FALSE Intermediate
## 594               0.0    TRUE       O-type
## 595               0.0   FALSE       C-type
## 596               0.0   FALSE       C-type
## 597               0.0   FALSE       C-type
## 598               0.2    TRUE       O-type
## 599               0.0   FALSE       C-type
## 600               0.1   FALSE       C-type
## 601               0.1   FALSE       C-type
## 602               0.0   FALSE       C-type
## 603               0.0   FALSE       C-type
## 604               0.1   FALSE       C-type
## 605               0.0    TRUE       O-type
## 606               0.1   FALSE       C-type
## 607               0.0   FALSE       C-type
## 608               0.1   FALSE       C-type
## 609               0.0   FALSE       C-type
## 610               0.1   FALSE       C-type
## 611               0.0   FALSE       C-type
## 612               0.0    TRUE       O-type
## 613               0.0   FALSE       C-type
## 614               0.1   FALSE       C-type
## 615               0.4    TRUE       O-type
## 616               0.4    TRUE       O-type
## 617               0.1   FALSE       C-type
## 618               0.1   FALSE       C-type
## 619               0.3   FALSE Intermediate
## 620               0.0   FALSE       C-type
## 621               0.1   FALSE       C-type
## 622               0.0   FALSE       C-type
## 623               0.0   FALSE       C-type
## 624               0.1   FALSE       C-type
## 625               0.0   FALSE       C-type
## 626               0.1   FALSE       C-type
## 627               0.0   FALSE       C-type
## 628               0.1   FALSE       C-type
## 629               0.1   FALSE       C-type
## 630               0.1    TRUE       O-type
## 631               0.0   FALSE       C-type
## 632               0.1   FALSE       C-type
## 633               0.0   FALSE       C-type
## 634               0.4    TRUE       O-type
## 635               0.0   FALSE       C-type
## 636               0.0   FALSE       C-type
## 637               0.0   FALSE       C-type
## 638               0.0   FALSE       C-type
## 639               0.0   FALSE       C-type
## 640               0.1   FALSE       C-type
## 641               0.2   FALSE Intermediate
## 642               0.1   FALSE       C-type
## 643               0.0   FALSE       C-type
## 644               0.1   FALSE       C-type
## 645               0.2    TRUE       O-type
## 646               0.2   FALSE Intermediate
## 647               0.1   FALSE       C-type
## 648               0.3   FALSE Intermediate
## 649               0.0   FALSE       C-type
## 650               0.0   FALSE       C-type
## 651               0.2   FALSE Intermediate
## 652               0.0   FALSE       C-type
## 653               0.0   FALSE       C-type
## 654               0.1   FALSE       C-type
## 655               0.0   FALSE       C-type
## 656               0.0   FALSE       C-type
## 657               0.0   FALSE       C-type
## 658               0.0   FALSE       C-type
## 659               0.0   FALSE       C-type
## 660               0.0   FALSE       C-type
## 661               0.1   FALSE       C-type
## 662               0.1   FALSE       C-type
## 663               0.1    TRUE       O-type
## 664               0.0   FALSE       C-type
## 665               0.1   FALSE       C-type
## 666               0.2   FALSE Intermediate
## 667               0.0   FALSE       C-type
## 668               0.0   FALSE       C-type
## 669               0.1   FALSE       C-type
## 670               0.0   FALSE       C-type
## 671               0.1   FALSE       C-type
## 672               0.0   FALSE       C-type
## 673               0.1   FALSE       C-type
## 674               0.2   FALSE Intermediate
## 675               0.1   FALSE       C-type
## 676               0.0   FALSE       C-type
## 677               0.1   FALSE       C-type
## 678               0.1   FALSE       C-type
## 679               0.0   FALSE       C-type
## 680               0.1   FALSE       C-type
## 681               0.0   FALSE       C-type
## 682               0.0   FALSE       C-type
## 683               0.0   FALSE       C-type
## 684               0.0   FALSE       C-type
## 685               0.0   FALSE       C-type
## 686               0.1   FALSE       C-type
## 687               0.0   FALSE       C-type
## 688               0.0   FALSE       C-type
## 689               0.1   FALSE       C-type
## 690               0.0    TRUE       O-type
## 691               0.1   FALSE       C-type
## 692               0.0   FALSE       C-type
## 693               0.1    TRUE       O-type
## 694               0.0   FALSE       C-type
## 695               0.2   FALSE Intermediate
## 696               0.0   FALSE       C-type
## 697               0.0   FALSE       C-type
## 698               0.1   FALSE       C-type
## 699               0.1   FALSE       C-type
## 700               0.1   FALSE       C-type
## 701               0.1   FALSE       C-type
## 702               0.0   FALSE       C-type
## 703               0.1   FALSE       C-type
## 704               0.1   FALSE       C-type
## 705               0.3    TRUE       O-type
## 706               0.0   FALSE       C-type
## 707               0.0   FALSE       C-type
## 708               0.0   FALSE       C-type
## 709               0.0   FALSE       C-type
## 710               0.0   FALSE       C-type
## 711               0.1   FALSE       C-type
## 712               0.0   FALSE       C-type
## 713               0.0    TRUE       O-type
## 714               0.1   FALSE       C-type
## 715               0.2   FALSE Intermediate
## 716               0.0   FALSE       C-type
## 717               0.0   FALSE       C-type
## 718               0.0   FALSE       C-type
## 719               0.1   FALSE       C-type
## 720               0.0   FALSE       C-type
## 721               0.0   FALSE       C-type
## 722               0.3    TRUE       O-type
## 723               0.1    TRUE       O-type
## 724               0.1   FALSE       C-type
## 725               0.0   FALSE       C-type
## 726               0.0   FALSE       C-type
## 727               0.2   FALSE Intermediate
## 728               0.1   FALSE       C-type
## 729               0.2   FALSE Intermediate
## 730               0.0   FALSE       C-type
## 731               0.1   FALSE       C-type
## 732               0.0   FALSE       C-type
## 733               0.0   FALSE       C-type
## 734               0.0   FALSE       C-type
## 735               0.0   FALSE       C-type
## 736               0.0   FALSE       C-type
## 737               0.2   FALSE Intermediate
## 738               0.0   FALSE       C-type
## 739               0.0   FALSE       C-type
## 740               0.0   FALSE       C-type
## 741               0.0   FALSE       C-type
## 742               0.0   FALSE       C-type
## 743               0.1    TRUE       O-type
## 744               0.0    TRUE       O-type
## 745               0.1   FALSE       C-type
## 746               0.0   FALSE       C-type
## 747               0.0   FALSE       C-type
## 748               0.0   FALSE       C-type
## 749               0.0   FALSE       C-type
## 750               0.1   FALSE       C-type
## 751               0.1   FALSE       C-type
## 752               0.1   FALSE       C-type
## 753               0.1   FALSE       C-type
## 754               0.3    TRUE       O-type
## 755               0.1   FALSE       C-type
## 756               0.1   FALSE       C-type
## 757               0.0   FALSE       C-type
## 758               0.1   FALSE       C-type
## 759               0.0   FALSE       C-type
## 760               0.0   FALSE       C-type
## 761               0.0   FALSE       C-type
## 762               0.1   FALSE       C-type
## 763               0.1   FALSE       C-type
## 764               0.0   FALSE       C-type
## 765               0.0   FALSE       C-type
## 766               0.1   FALSE       C-type
## 767               0.1   FALSE       C-type
## 768               0.0   FALSE       C-type
## 769               0.0   FALSE       C-type
## 770               0.0   FALSE       C-type
## 771               0.0   FALSE       C-type
## 772               0.1   FALSE       C-type
## 773               0.1   FALSE       C-type
## 774               0.2   FALSE Intermediate
## 775               0.0    TRUE       O-type
## 776               0.0   FALSE       C-type
## 777               0.0   FALSE       C-type
## 778               0.0   FALSE       C-type
## 779               0.1    TRUE       O-type
## 780               0.1   FALSE       C-type
## 781               0.0   FALSE       C-type
## 782               0.2   FALSE Intermediate
## 783               0.0   FALSE       C-type
## 784               0.0   FALSE       C-type
## 785               0.0   FALSE       C-type
## 786               0.1   FALSE       C-type
## 787               0.1   FALSE       C-type
## 788               0.0   FALSE       C-type
## 789               0.0    TRUE       O-type
## 790               0.0    TRUE       O-type
## 791               0.0   FALSE       C-type
## 792               0.1   FALSE       C-type
## 793               0.3   FALSE Intermediate
## 794               0.0   FALSE       C-type
## 795               0.1   FALSE       C-type
## 796               0.0   FALSE       C-type
## 797               0.0   FALSE       C-type
## 798               0.0   FALSE       C-type
## 799               0.0   FALSE       C-type
## 800               0.0   FALSE       C-type
## 801               0.0   FALSE       C-type
## 802               0.0   FALSE       C-type
## 803               0.0    TRUE       O-type
## 804               0.3   FALSE Intermediate
## 805               0.0   FALSE       C-type
## 806               0.1   FALSE       C-type
## 807               0.0   FALSE       C-type
## 808               0.0   FALSE       C-type
## 809               0.1   FALSE       C-type
## 810               0.0   FALSE       C-type
## 811               0.2    TRUE       O-type
## 812               0.0   FALSE       C-type
## 813               0.0   FALSE       C-type
## 814               0.0   FALSE       C-type
## 815               0.2    TRUE       O-type
## 816               0.1   FALSE       C-type
## 817               0.0   FALSE       C-type
## 818               0.0   FALSE       C-type
## 819               0.0   FALSE       C-type
## 820               0.0   FALSE       C-type
## 821               0.0   FALSE       C-type
## 822               0.0   FALSE       C-type
## 823               0.1   FALSE       C-type
## 824               0.1    TRUE       O-type
## 825               0.0   FALSE       C-type
## 826               0.1   FALSE       C-type
## 827               0.0   FALSE       C-type
## 828               0.0   FALSE       C-type
## 829               0.0   FALSE       C-type
## 830               0.0   FALSE       C-type
## 831               0.1   FALSE       C-type
## 832               0.0   FALSE       C-type
## 833               0.0    TRUE       O-type
## 834               0.0   FALSE       C-type
## 835               0.0   FALSE       C-type
## 836               0.0   FALSE       C-type
## 837               0.2   FALSE Intermediate
## 838               0.0   FALSE       C-type
## 839               0.0   FALSE       C-type
## 840               0.1   FALSE       C-type
## 841               0.1   FALSE       C-type
## 842               0.0   FALSE       C-type
## 843               0.0   FALSE       C-type
## 844               0.0   FALSE       C-type
## 845               0.0   FALSE       C-type
## 846               0.1   FALSE       C-type
## 847               0.0   FALSE       C-type
## 848               0.1   FALSE       C-type
## 849               0.0    TRUE       O-type
## 850               0.1   FALSE       C-type
## 851               0.0   FALSE       C-type
## 852               0.1   FALSE       C-type
## 853               0.0   FALSE       C-type
## 854               0.1   FALSE       C-type
## 855               0.0   FALSE       C-type
## 856               0.0   FALSE       C-type
## 857               0.1   FALSE       C-type
## 858               0.1   FALSE       C-type
## 859               0.3   FALSE Intermediate
## 860               0.0   FALSE       C-type
## 861               0.0   FALSE       C-type
## 862               0.0   FALSE       C-type
## 863               0.0   FALSE       C-type

BMI

BMI <- as.numeric(sample_data(ps)[["BMI..kg.m.."]])
## Warning: NAs introduced by coercion
keep <- !is.na(BMI)   
ps_filt <- prune_samples(keep, ps)  
BMI_filt <- as.numeric(sample_data(ps_filt)[["BMI..kg.m.."]])
dist_bray_filt <- phyloseq::distance(ps_filt, method = "bray")
res <- BetaTREND::gradient_projection(dist_bray_filt, BMI_filt)

res
## $projection_scores
##   [1] -1.2404844503 -0.5796865175 -0.2536391266  0.1306683164  2.3309542648
##   [6] -1.5852769168  0.3529624692 -0.0204311000 -0.9809306770 -0.1595297103
##  [11]  0.3930839072  0.9467020449 -0.2590730871  0.8959298264  0.0454274663
##  [16]  0.0774525889  2.2993417799 -0.1278243678  0.2383666355 -0.8014258836
##  [21]  0.0941429626  0.5944123699 -0.3551839951  3.0197649012  0.6809267742
##  [26]  1.0193625053  2.7063885158  1.4519340950 -0.2540291884 -0.0953831217
##  [31] -0.9328082477 -0.3136486261  1.8763115260 -1.1995108446 -0.3801167614
##  [36]  0.6031292819  0.3348314639  1.7250283915 -1.6779054840  0.5870846614
##  [41] -1.0056986740 -0.5674784302  0.3379637729  1.7392465656 -0.1230702613
##  [46]  0.6798410694 -0.7708133643  0.4874832062  0.3616497250 -0.5992463604
##  [51] -1.4459207427 -1.2524019705 -0.9673664657 -1.4711721725 -1.0323970573
##  [56]  1.2755235786 -1.2018631141 -0.6373815261  0.3054132239 -0.4476240440
##  [61] -0.9420834932  0.4796073493 -0.7496767060  2.0426501611 -0.7916042634
##  [66] -0.9662965525 -0.4963093453 -1.1162410732 -0.7293097163 -0.0181694704
##  [71] -1.3714786485 -0.3668899342 -0.0368014283  0.1943139356 -1.4127970179
##  [76] -0.3144310670  0.5632504003 -0.9152620016  0.1137403056  2.0242602988
##  [81] -1.0410878490 -1.6290402446  1.1585307896  0.0080114830 -0.8844649026
##  [86] -1.3957870706 -0.3478026063 -0.9179847916  1.0440762725  0.1798327542
##  [91] -1.2082675314 -2.1064037055 -0.0370672772 -1.6945159708 -0.9671433316
##  [96] -1.5867656922 -2.0919800967 -1.5882203721 -0.2548015032 -1.1591220786
## [101] -0.8932592039 -1.5986577154 -0.2676585957  0.7076936646 -1.5208957549
## [106]  0.3265484368 -1.2287512176  0.2992416353  0.0481957965 -0.1027518394
## [111] -1.2171839644  0.6271577509 -0.9325122655  0.7329583938  0.1861904682
## [116] -1.1132756492  1.3728898921 -0.6799385613 -0.0549172846  0.4176643311
## [121] -0.7516860398 -1.2611175029 -0.2841062493  0.6785568711  1.1719013861
## [126]  0.5419814713 -0.5290222278 -0.4452242525 -0.3869926877  0.4411965581
## [131] -0.4527147546  0.6343460747 -1.3440210839 -1.2217988139  1.6633347540
## [136]  0.5040897746 -0.5961703916  0.2994859710 -0.0298225706  0.9331210105
## [141] -0.2481730852 -1.2259638648  1.6798697299 -0.9022800324  0.3634394794
## [146] -1.7089984899 -1.2061284778  0.5773487564 -0.5890371466  0.7497984781
## [151] -0.4380198608 -0.8201005700  0.1490678744  1.3147959494 -1.6100819415
## [156]  1.0079955488 -1.8280425796  0.1985209678 -0.0535964543 -1.4756523525
## [161]  0.1990316786  1.6963550077  0.1292979086  1.9240859097  1.3183363302
## [166]  0.3666401808 -0.9613520859 -1.1678006043 -0.0523546194 -0.3627529344
## [171] -0.7132515529  2.0612869657 -1.5358460798 -1.4442436114 -0.8702561720
## [176]  1.9247004829  0.2404753556 -0.2837770096 -1.7018540942 -0.4520774065
## [181]  1.4825172969 -1.2901080911  0.1505974165 -1.4646216094 -0.2099097418
## [186] -0.4983497736  0.3651053140  1.6579520009  1.3912117225  1.9617022334
## [191]  3.2188330620  0.0577302613 -1.2395922761 -1.3982406556 -1.6210808879
## [196] -1.7887451220 -1.3358460405  1.3057342480 -0.5532605418  0.5030903741
## [201]  0.4584873865 -0.9119512233  0.6875457739  0.0914076148  0.4718528890
## [206] -0.5373352901 -0.4683485262  2.2551312709 -1.0036257163  0.9933012533
## [211]  1.1263370304  2.6591493674 -1.4327766702 -0.3798217783  1.0466743925
## [216] -0.9295602000  0.6975512147 -1.1038099899  0.7272212211 -0.0608685153
## [221] -0.5710119716 -0.4407321160 -1.3791626344  0.6290483088  1.3173830308
## [226] -1.5258962117 -1.0438124020 -0.8252726158  0.6917622898  1.0398841387
## [231] -1.2914962612 -0.7156399734 -0.7647658502 -1.1268837399 -0.4212346299
## [236] -0.5277601231 -0.2094851630 -1.4847643480  0.7613217240 -1.3443201558
## [241] -0.7624983629 -0.3819375568 -1.0780775506  2.1484151832 -2.4132613365
## [246]  0.4386376204 -0.7125086290 -1.3438840301 -0.1620562236 -0.4168718873
## [251]  0.7793887603 -0.3673418494 -1.5346403320 -1.6152520201 -0.7056980987
## [256] -0.3500713852 -1.0560468381 -1.2568227395  0.4352122814 -1.6893236892
## [261]  0.3889160846 -0.5907765212  0.0365824756 -1.7441507549 -0.4740672275
## [266]  0.1017521563 -0.5828622367  1.1123137654 -1.0515603225  0.3568789287
## [271] -0.8278629764 -0.2228609181  0.3614943606 -1.1405805170 -1.4172390541
## [276] -0.2802240808 -1.5303094606 -0.8213204234 -0.5829327117 -2.1713809758
## [281] -1.1665246935 -0.0523561467 -0.5059678016 -0.3441760725 -0.3727686123
## [286]  0.4596897471 -1.7943774245  0.0973722832 -0.6500678017  0.7632689344
## [291] -1.2080314500 -0.8054157691 -1.6961215281  1.7166692618 -1.5634319700
## [296] -1.7476848144 -0.5703012391 -0.3755830560 -0.2688144208 -0.6818336391
## [301] -0.7383875446  0.0423212550 -1.5325394553 -0.5561004874 -1.6051313243
## [306] -1.0474502411 -1.1624115933  1.2178908998  2.0295118946 -0.8568959204
## [311] -1.0060331661 -0.1575603007 -0.9595531587 -0.5546585482 -1.3374701042
## [316] -1.0429824245  0.4495304453  0.6056665352 -1.6192000599  0.1594069096
## [321] -0.5809516687 -1.1127488386 -1.2506900958 -0.5366340210 -0.7707120013
## [326] -0.7658303316  0.3378299351  2.2383969520  0.0186715087 -1.3729042031
## [331] -1.2629296435 -1.1343738082 -1.6463848653 -0.5500241770  0.0116990479
## [336]  0.5431396127 -1.7981240865 -0.8524991202 -0.6319858667 -0.9350647618
## [341]  0.9759262113  0.6002626170 -1.0966039625 -0.7048285240 -0.7164129512
## [346] -1.2936896025 -0.0034759438 -0.7531737637 -0.1407056945 -1.9341205824
## [351] -1.2592268476 -0.8883716907 -0.3291728482 -1.4909197062 -0.6341614478
## [356] -1.0231236574 -1.4955507896 -0.6499548046  0.9213804880 -0.8434465587
## [361] -0.4298486558  1.7472782456 -1.0933300444  0.2800129233  0.5365694804
## [366] -1.2773556664 -1.2821109179 -1.5768803137 -1.3707284144  0.2369183992
## [371] -0.6716775214  0.8377513686  1.1617376360 -0.7670664782  1.2370904935
## [376]  0.0549764178 -1.7828138512  1.4002128584 -0.7604475138  0.1046071154
## [381] -1.3615810240 -1.8700680605 -1.1010640873 -0.3401192921 -0.3909127843
## [386]  1.1046737081  0.2969145599  0.7198103345 -0.3273089159 -0.8841059174
## [391] -1.7131412697  0.4416019087 -0.2819689524 -0.7465661997  0.8404353378
## [396]  1.2960623113  0.8467471260 -1.6422677245  0.3213799326 -0.9453176867
## [401] -0.9870534126 -1.6412878447 -0.1127868806  0.1981317390 -1.5855239565
## [406] -1.2864288255  0.0576811397  0.1555456354  0.8540443327  0.0150849345
## [411]  3.0666764765  0.1711947920  0.0594419290  1.1101165397  1.9028871147
## [416] -1.0771886033  1.3386992119  0.0200496534 -0.6391263602  1.3272037172
## [421]  1.0886614019 -1.3565599302  0.0022556112 -1.1287593743 -1.5798089719
## [426]  3.2272302077 -0.1159784942  0.9427372708  1.5593840385  1.0614552993
## [431] -0.5758990055  0.6816780988  1.8649096502  1.5846184952 -0.6227600212
## [436]  0.0118549092 -1.2922376610  2.1372494238  2.1765590379 -0.1276542261
## [441]  0.9207083787  0.6730771115 -0.4363233872  1.7591443673 -0.8703605111
## [446]  1.4937914041 -0.6215758576 -0.1577171414 -0.2982167896  0.9670019582
## [451]  0.4575066924  1.4126940119 -1.6013088148  1.6812984425 -0.8834140152
## [456] -1.2463519256  2.2880258395  1.4097831512 -0.9428449242  1.6884685981
## [461]  0.6956521197  3.1582284016 -1.0444922855 -0.7522129787  0.3360188702
## [466]  0.1266676673  2.6091318556  1.3792767627  2.2709020884  1.3235577539
## [471] -0.4397985015  1.7478064790  2.2886012134  2.4537425794  0.9342154874
## [476]  0.1024331543  1.2645365615 -1.3269989466  1.0783016495  1.0248742223
## [481] -0.1750808504  1.8898371020  2.1526124868  0.7523364171 -0.5563872120
## [486] -0.6945595465 -0.1246679538  2.5138241472  3.2533276601  1.4296099710
## [491]  0.4316671921  2.2635777107  2.1286903480  0.9590660328  0.3370037938
## [496]  0.8597498802  1.3938700797  1.6436050318 -1.2655695738  2.1592897829
## [501]  2.0345692568 -1.9673589540  2.8459791746  1.9668957029 -0.6783512964
## [506]  1.1734618143  1.1382779011  2.5941564139  0.3946327025  0.1823005512
## [511]  2.4402307996 -0.7052631014 -0.7715848636  2.2055510037 -0.8363524003
## [516] -0.1209297108  2.4959702455 -0.1960726840 -1.8318550872 -0.6098181486
## [521]  1.0408859100  1.2681028370 -2.0070464284 -1.0951353972  0.5466110617
## [526]  0.1665614076 -0.1955590368  2.2092027705  0.1480059031  0.3898493034
## [531] -0.5011777145 -0.1134038032  0.1480877610  1.5824118666  1.6075663016
## [536]  1.5178100522 -0.2253542140  1.4677969219  0.1134969745 -1.1959699551
## [541]  0.3645460070  1.2249977059  0.4628885074  0.8059290115 -0.1917153486
## [546]  1.1507806668 -0.7475001421  1.3047146443 -1.7282518311 -1.2405644278
## [551]  0.8087872064 -0.6276718171  0.3273646967  2.0660975069 -0.9242120464
## [556]  2.4324746648  0.5353764490 -2.4241223382  0.2659550854 -0.0264444112
## [561]  0.9111587569  1.0498388142 -0.3354976648  0.0913722870 -0.0869899247
## [566] -0.3789564160 -0.9786115810  1.3631311847 -0.2481556361  0.6841260518
## [571] -0.2101558595  0.1924338407  0.5803131166  0.0974885414  0.9020930641
## [576]  1.5060517346 -1.5154506069 -0.3975022520 -0.9777979866 -0.3812483231
## [581] -0.9072768969 -0.5482565419 -1.7890187855  1.0892332452  0.2766065336
## [586]  1.6468017251 -1.3435037203  1.0027388474  0.5233121822 -1.7292252016
## [591]  2.3393096690 -1.9177162677  0.2780494314  1.9627219731  1.6014571942
## [596]  1.0834318297  0.3252940052  0.0576108106 -0.0707461743 -1.2207147976
## [601] -0.7978155405  1.8681374852 -0.6649819670 -0.7497334498  1.9928851987
## [606] -0.5005302631 -1.5902761930  0.5403473298  0.6212508746  0.3545681797
## [611]  0.8709002040  1.1376301978  1.0213686118 -0.3192332619  0.5623363190
## [616] -0.4927564448 -0.3114728299 -0.7511597636 -0.5055256647  0.5001941925
## [621]  1.0052590530 -1.0053286762  0.5671572842 -0.5849090528  0.3973566144
## [626]  0.8191612354  0.3750045425  0.8806054050 -0.8873893440  0.5650127891
## [631] -0.1821338604 -2.4022051793 -0.3100540598 -0.6068062513 -0.1458823767
## [636]  0.1556615305  0.4257664258 -0.6565024797  0.4038373209 -0.3457589847
## [641]  0.7821724697  1.8398912619 -1.2366580346  1.6465052149 -1.9247402233
## [646] -0.2125387891  0.2813935615 -0.0891099397  2.6228081622 -0.6316583742
## [651]  1.1587570832 -0.2606001225 -0.1724894601  1.2237061285 -0.5789124836
## [656] -0.1949271712  0.0419258683  1.5791198272  0.1410669163 -0.9993146032
## [661] -1.6698006833 -1.5198920639 -0.9387386967  0.9981171708 -0.1545880301
## [666]  1.8707768677 -0.6902454210  0.2229389844  1.7329555981  2.0131208457
## [671] -1.2896462312 -0.0732787149  1.5292685380  1.4779231126  1.0800535454
## [676] -1.3737321518  0.1448693483  1.5147102446 -0.4548228483  1.8618873158
## [681] -1.9374300648  1.0575743105 -0.0005854733 -1.5624865867 -0.4481376570
## [686]  1.3182738111 -1.4639391210 -1.6936456374  0.3701174296  0.2957664265
## [691]  1.1484212987  0.1336006431 -0.4709451204 -0.8657936207 -1.3175766670
## [696] -0.8480244875  0.5715050075  1.1512471785 -0.7669603017 -1.1947614700
## [701]  0.3893475296 -1.5173107908 -0.2869079100  0.4535787716 -0.1070025716
## [706]  1.7665192668  0.8100211457 -1.5573903563 -1.2131371855  1.2109601484
## [711]  0.1769032070 -1.5764280890  2.3375744517 -0.7312184099  0.8221597331
## [716] -0.7883654593 -0.6791246303 -0.4518236330 -0.3600324116  1.5890896851
## [721]  1.2277835385  0.6058768117 -0.5753675833  0.2779352671 -1.0758055299
## [726] -0.7781870315  0.4948740773 -0.4046831207  0.2046517727 -0.1176727926
## [731]  0.1820272152  0.0505384400 -1.4528755318 -1.1971984458  0.1454976533
## [736] -0.3047456013 -0.6397169442 -0.8081048320  0.4200523728 -1.0272355576
## [741] -0.6135208154 -0.9965157773  1.2159284141  1.2081663148 -0.0849610415
## [746]  1.4084396038  0.9594515301  0.5316922535 -0.3149936489  0.4050234425
## [751]  0.9211463457 -0.4306010818  1.6170601249 -1.1168155446  2.0501553406
## [756] -1.3508759583  0.1472232574 -0.5043573303 -0.6898567487 -0.6193206276
## [761] -1.2308250108 -0.5739164423  0.5352577488  1.9297600951 -0.2133877114
## [766]  0.3199970966  0.5247519702 -0.8782735773 -0.9600122395  0.4794870325
## [771] -0.9028015830 -0.0291822391 -0.2690934357  0.2410339027  0.5283014454
## [776] -0.0719006038 -0.6594632044 -1.8273994149  1.3627223541  0.1302451827
## [781]  0.8927051139  1.3756584422 -0.4641960800  1.3028314998  1.7582115193
## [786]  0.8326476881 -0.2656350974  0.4154269920 -0.5733324808 -1.0272914804
## [791]  0.6470747127 -0.4554371349  0.8777311860  0.3964653938  1.2530419619
## [796]  0.2368423353  0.2403670998  1.0344304525 -0.7528565444 -0.0072008234
## [801] -0.7020362993  0.9592997530  2.1718965288  0.3892356033  0.1766484022
## [806]  0.8277605352  0.7612685841 -0.8657308307 -0.2721529354 -0.8523588755
## [811]  0.1677497763  0.6364659503 -2.0570762057 -0.3131403785 -1.1572152005
## [816]  0.6721943185  0.1197395214  0.6606381104 -0.6172987357 -1.2807003679
## [821] -0.9637474864  1.9437342109  1.9225906855 -1.9004870541 -2.3328360728
## [826]  1.2429844115 -0.5784755363 -1.6421045234  0.6859715689  2.1292407939
## [831]  0.6299126017  2.3707577019  0.6258110661  0.5174164069 -1.7744274206
## [836] -0.6955480865 -1.3736050919 -0.8263862705  0.5577037148  0.6699747471
## [841]  0.6810678947  0.7391404597 -1.7680085748  2.4784036197 -0.0267298635
## [846]  1.4115590615  2.6415335722 -1.7071163526 -0.2380929626 -1.7632937159
## [851]  1.6929900369 -0.3189038683  2.9966925195  2.5843349978
## 
## $gradient_direction
##           [,1]
## [1,] -2.273831
## [2,] -2.946673
## [3,] -4.245777
## [4,]  6.330816
## [5,] -2.156127
## 
## $PCoA_coordinates
##                     [,1]          [,2]          [,3]          [,4]
## x10MCx1146  2.290337e-01  0.2684857642 -8.545920e-02 -3.642271e-02
## x10MCx1176 -1.770835e-01  0.0287491703  1.067543e-01 -6.996995e-02
## x10MCx1206 -7.297256e-02  0.0857296991  1.139994e-01  9.857517e-02
## x10MCx1350 -4.163358e-02  0.1227653325  7.305724e-02  1.196577e-01
## x10MCx1390 -3.262454e-01 -0.0496009801 -1.432709e-01  1.034116e-01
## x10MCx1529  1.180536e-02  0.0728947088  1.091652e-01 -1.337057e-01
## x10MCx1563  2.135756e-01  0.1914264597 -4.613557e-01 -3.484591e-02
## x10MCx1585 -6.827862e-03  0.1624473740  6.531586e-02  1.568801e-01
## x10MCx1667 -5.026476e-02  0.0521551480  1.175469e-01 -5.364425e-02
## x10MCx1745 -1.004248e-01  0.1224208423  1.103376e-01  4.918000e-02
## x10MCx1810  1.018166e-01  0.2731835189 -9.934222e-02  1.824386e-01
## x10MCx1936 -2.582773e-01  0.0322599637  5.842575e-02  1.033556e-01
## x10MCx2044 -1.854105e-01  0.0283685331  4.877880e-02 -5.225101e-02
## x10MCx2066 -2.424921e-01 -0.0630376876 -3.754371e-02  4.490153e-03
## x10MCx2097  1.200098e-01  0.2036502990 -6.382235e-02  1.451065e-01
## x10MCx2262  2.480319e-01  0.2212885556 -3.995678e-01 -1.994307e-02
## x10MCx2294 -3.352974e-01 -0.1236687553 -2.281566e-01  5.328440e-03
## x10MCx2392 -1.560620e-01 -0.0073969663  1.144283e-01  2.323502e-02
## x10MCx2550  2.424964e-01  0.2836455320 -3.623301e-01  6.535427e-02
## x10MCx2839 -4.682215e-02  0.0510186567  7.261967e-02  4.207792e-03
## x10MCx2862  1.096022e-01 -0.3642869949  4.123116e-02 -3.443910e-02
## x10MCx3024  3.493005e-01 -0.1729617470  1.506579e-03  1.069463e-01
## x10MCx3098 -1.785223e-01 -0.1655017800 -1.200070e-01 -2.278736e-01
## x10MCx3111 -3.359503e-01 -0.1270233042 -2.592745e-01  9.060270e-02
## x10MCx3144 -1.552180e-01  0.0043513828  3.719065e-02  7.898256e-02
## x10MCx3329 -1.632050e-01  0.0018472504 -6.582224e-02  1.036302e-01
## x10MCx3358 -2.685323e-01 -0.0753990559 -2.281813e-01  1.298118e-01
## x10MCx3391 -8.863372e-02  0.1701942320 -3.208993e-02  2.825635e-01
## x10MCx3419  3.387553e-01 -0.1374692076 -7.362684e-03 -4.033143e-02
## x13MCx1129  3.562068e-01 -0.1987187929  4.992179e-02  1.884085e-02
## x13MCx1340 -9.975865e-02  0.0711687231  1.561376e-01 -2.163364e-02
## x13MCx1381 -1.453409e-01 -0.0145975119  8.667360e-02 -6.526003e-03
## x13MCx1398 -2.023155e-01 -0.0334875635 -1.224113e-01  1.436450e-01
## x13MCx1416  6.567218e-02  0.0029644276  6.551565e-02 -1.643057e-01
## x13MCx1553 -1.585240e-01 -0.0130035775  8.837646e-02 -6.425632e-02
## x13MCx1818 -1.780236e-01 -0.0878362971 -8.642609e-02 -1.781178e-02
## x13MCx2054 -5.676322e-02  0.1194447424  4.313880e-02  1.518763e-01
## x13MCx2232 -2.905837e-01 -0.1357546518 -1.593229e-01  2.833204e-03
## x13MCx2282 -4.859441e-02  0.0464331701  1.428653e-01 -1.179288e-01
## x13MCx2401 -2.368714e-01  0.0109388394  7.937245e-02  6.726847e-02
## x13MCx2621  2.651317e-01 -0.1764538020  8.960913e-02 -1.042474e-01
## x13MCx2699 -1.833283e-01 -0.0036223702  1.162348e-01 -5.337420e-02
## x13MCx2743  3.453097e-01 -0.3250826280  4.234344e-02  7.342634e-02
## x13MCx2963 -2.657120e-01 -0.1213830983 -1.961320e-01 -9.666711e-04
## x13MCx2965  4.063738e-01 -0.1122481366 -1.534182e-02  1.192427e-02
## x13MCx3205  3.723766e-01 -0.3533946951 -5.311432e-02  3.262334e-02
## x13MCx3311 -4.696751e-03  0.1197827033  1.160048e-01  6.154345e-02
## x13MCx3383  1.272104e-01 -0.3677588794  4.023923e-02  4.737927e-02
## x14MCx1118 -2.421307e-01  0.0189040332  3.933799e-02 -3.310463e-02
## x14MCx1158 -4.099406e-03  0.1849246910  1.098591e-01  5.938512e-02
## x14MCx1190  6.306038e-02  0.1772872901  1.174065e-01 -3.383316e-02
## x14MCx1209  6.123082e-02  0.1089879089  1.101935e-01 -6.855101e-02
## x14MCx1227  4.776496e-02  0.1936420997  9.399809e-02  4.591837e-02
## x14MCx1302  9.889392e-02  0.2243468684  5.652978e-02 -5.704965e-02
## x14MCx1313 -7.813990e-02  0.0449487285  1.358665e-01 -4.945092e-02
## x14MCx1363  3.931660e-01 -0.3845806084 -5.293497e-02  1.486169e-01
## x14MCx1397  1.510274e-01  0.1773704093  3.967057e-02 -1.401534e-02
## x14MCx1399  3.054794e-01  0.1389044526 -1.033977e-01 -1.355718e-02
## x14MCx1485  2.300827e-01  0.2167577432 -4.716519e-01 -2.404427e-02
## x14MCx1540 -1.377192e-01  0.0959169727  1.360745e-01  2.268399e-02
## x14MCx1551  3.073418e-01  0.0075852407  3.623133e-02 -5.447022e-02
## x14MCx1578 -1.947938e-01  0.0209076273  6.551534e-02  6.526237e-02
## x14MCx1583  1.485179e-02  0.1918232726  8.477204e-02  6.643446e-02
## x14MCx1612 -2.758354e-01 -0.0340187504 -9.613275e-02  1.369356e-01
## x14MCx1616  3.539202e-02  0.1806069248  9.401379e-02  4.736331e-02
## x14MCx1621  2.087922e-01  0.1803399111  1.307728e-02 -2.427326e-02
## x14MCx1706  1.517467e-01  0.3035423464 -6.791590e-02  8.531875e-02
## x14MCx1724 -1.537156e-02  0.1750139618  1.124620e-01 -2.740600e-02
## x14MCx1739  5.509960e-02  0.2127088440  5.905926e-02  5.439304e-02
## x14MCx1747 -1.841993e-01  0.0108951719  4.986278e-02  4.413796e-03
## x14MCx1768  2.177105e-01  0.1831589636  5.032211e-02 -3.293971e-02
## x14MCx1775  3.252794e-01  0.2380289716 -2.755828e-01 -1.655212e-02
## x14MCx1798  3.177239e-01  0.1555436499 -1.944371e-01  1.780318e-02
## x14MCx1861  2.858907e-02 -0.3687961345  4.960149e-02 -3.473388e-02
## x14MCx1910  1.303647e-01  0.2009854309  3.874829e-02 -6.140624e-02
## x14MCx1914  7.486010e-03  0.1731877669  5.911142e-02  9.955852e-02
## x14MCx1916 -1.785047e-01  0.0743978284 -6.493489e-03 -6.508083e-03
## x14MCx1929  3.100434e-01  0.0505505364 -5.850399e-02 -1.038300e-01
## x14MCx1940  2.469731e-01  0.1935886982 -4.501455e-01 -6.091596e-02
## x14MCx1943 -1.012086e-01 -0.3811374401 -5.921826e-02  9.105031e-02
## x14MCx1953  9.644476e-02  0.2189247845  1.102077e-01  7.222353e-02
## x14MCx1965  2.147789e-01  0.2159403103 -3.864411e-02 -1.212880e-01
## x14MCx1997 -2.002810e-01  0.0925703240  3.886420e-02  1.735400e-01
## x14MCx2055 -2.094274e-01 -0.0222578287  6.443134e-02 -2.094915e-03
## x14MCx2088  7.239488e-02  0.2326181890  5.695156e-02  4.687525e-02
## x14MCx2162  2.390733e-01  0.0814587223  7.908132e-02 -7.027854e-02
## x14MCx2193  3.843208e-01 -0.0425824504 -1.532578e-01 -1.113928e-01
## x14MCx2220  4.034786e-02  0.1945920925  1.102567e-01  3.255243e-02
## x14MCx2237  7.037938e-02 -0.2944732768  8.461209e-02  1.427094e-01
## x14MCx2263  3.633492e-01 -0.1459489044  4.137996e-02  9.260562e-02
## x14MCx2269  7.105854e-02  0.0278241220  7.912117e-02 -9.753928e-02
## x14MCx2325  9.264475e-02  0.1587614450  1.152626e-01 -1.507857e-01
## x14MCx2355  2.851705e-01 -0.1721815028  9.906145e-02  8.304258e-02
## x14MCx2365  1.018078e-01  0.1955573501  1.329433e-01 -2.134909e-02
## x14MCx2381  1.640260e-02  0.1810224542  1.158640e-01  3.372882e-02
## x14MCx2393  1.754226e-01  0.1496120964  4.625660e-05 -1.151744e-01
## x14MCx2420  1.265474e-01  0.0294725167  1.051737e-01 -2.119220e-01
## x14MCx2429 -2.107889e-02  0.0534504421  1.568197e-01 -9.752134e-02
## x14MCx2437 -2.085879e-01 -0.0132466219  8.323952e-02 -5.835966e-02
## x14MCx2453  1.516328e-01 -0.0765392123  1.049650e-01 -1.214091e-01
## x14MCx2468 -3.138690e-02  0.1293170891  1.259777e-01 -5.031749e-04
## x14MCx2479  1.736553e-01  0.0944057008  1.223869e-01 -7.617266e-02
## x14MCx2494 -7.434646e-02  0.1274587108  1.335706e-01  8.834566e-02
## x14MCx2498 -2.279551e-01 -0.0401330096  1.242718e-02  6.384368e-02
## x14MCx2510  1.560734e-01  0.1724940876 -7.029427e-02 -1.414389e-01
## x14MCx2563 -9.878190e-02  0.1183117678  8.762507e-02  1.597930e-01
## x14MCx2587  2.199225e-01  0.0171036288  8.866160e-02 -7.121374e-02
## x14MCx2601  2.128848e-01  0.2155463182 -4.459009e-01 -2.351019e-02
## x14MCx2641 -9.747109e-02  0.1559779663  1.168871e-01  1.337562e-01
## x14MCx2645  3.097586e-01 -0.1157375424  7.975846e-02  6.296642e-02
## x14MCx2670  4.996738e-02  0.0486390877  1.160210e-01 -7.135105e-02
## x14MCx2682  9.119134e-02 -0.2801317661  1.192095e-01  1.019510e-01
## x14MCx2741 -8.340931e-02  0.0879519589  1.505684e-01 -2.782642e-02
## x14MCx2749 -1.579183e-01  0.0765079871  8.143215e-02  1.581302e-01
## x14MCx2756 -1.539629e-01  0.1186027875  1.054870e-01  9.516354e-02
## x14MCx2818  1.013304e-01  0.0751769211  8.554337e-02 -5.779458e-02
## x14MCx2842  4.687338e-01 -0.2677799599 -9.916446e-02  1.679338e-01
## x14MCx2903  1.445294e-01  0.2406786360 -1.172575e-01 -9.485391e-03
## x14MCx2932  2.408699e-01  0.3031995098 -2.526077e-01  8.814369e-02
## x14MCx2945  2.945003e-01 -0.2923195728  7.851805e-02  1.198272e-01
## x14MCx2961 -5.250327e-02  0.1309396709  1.491245e-01  2.872693e-02
## x14MCx2968  1.942597e-01  0.1829263573 -1.871478e-02 -9.630758e-02
## x14MCx2979  2.502056e-01  0.2951667177 -2.483544e-01  5.368028e-02
## x14MCx2986 -1.277776e-01  0.0926556034 -1.898451e-02  5.323795e-02
## x14MCx3041  2.702605e-02 -0.3359911314  6.002531e-02  1.119889e-01
## x14MCx3050 -5.591061e-02 -0.3243436010  2.139747e-02 -4.618816e-02
## x14MCx3150 -1.277976e-01  0.0645135648  1.300615e-01 -4.421019e-03
## x14MCx3229 -1.016912e-02 -0.0847057452  6.016846e-02 -3.902765e-02
## x14MCx3258  1.607739e-01 -0.0605582194  1.244413e-01  2.099785e-02
## x14MCx3320 -2.058467e-01 -0.0144849174  6.877091e-02  6.352925e-02
## x14MCx3348 -1.642593e-01  0.0412747137  1.040946e-01 -3.734146e-02
## x14MCx3378  4.375085e-01 -0.0889232341 -1.957818e-01  1.460624e-02
## x14MCx3397  3.604342e-02  0.1335561267  1.095788e-01 -4.275130e-02
## x14MCx3405 -4.873649e-03  0.0688348918  9.106930e-02 -1.105266e-01
## x20MCx1115 -2.966761e-01  0.0063761582 -2.349304e-02  1.217295e-01
## x20MCx1122 -1.884422e-01  0.0622146780  8.173447e-02  1.217086e-01
## x20MCx1125 -1.172737e-01 -0.0079648483  4.290337e-02 -1.115621e-01
## x20MCx1181  1.863709e-01 -0.3159660740  9.687797e-02  7.096244e-02
## x20MCx1184 -1.800942e-01  0.0596771577  7.125049e-02 -1.830561e-02
## x20MCx1203 -3.185096e-01 -0.0712267222 -3.028023e-02 -2.712826e-02
## x20MCx1252  4.022575e-01 -0.2412822756  3.907544e-02 -9.432382e-03
## x20MCx1263 -1.118581e-01  0.0606624817  1.824738e-01 -6.208393e-02
## x20MCx1264 -2.534493e-01 -0.0333106389 -1.065839e-01  6.889842e-02
## x20MCx1278  2.953324e-03  0.1687696310  1.303928e-01  4.406353e-02
## x20MCx1332 -2.287131e-01  0.0349043530  7.230280e-02  5.206500e-02
## x20MCx1366 -5.419885e-02  0.0357146621  1.244709e-01 -1.796854e-01
## x20MCx1393  1.177501e-01 -0.1296281119  1.203171e-01 -1.294579e-01
## x20MCx1424 -3.107933e-01 -0.0820205567 -1.471575e-02 -5.501139e-02
## x20MCx1469 -4.494667e-02  0.1006924558  9.799061e-02  2.186408e-02
## x20MCx1478 -2.122581e-01  0.0541989199  5.040204e-02  1.067024e-01
## x20MCx1492  2.989790e-01 -0.0673254673  4.192278e-03  3.007740e-03
## x20MCx1559 -1.585327e-01  0.0224278774  1.279648e-01 -8.147143e-02
## x20MCx1631  1.935485e-01 -0.2796186332  1.073560e-01  6.184196e-02
## x20MCx1634 -1.406102e-01  0.1027358880  1.285376e-03  1.527064e-01
## x20MCx1665  7.820247e-02  0.0651816278  1.164936e-01 -1.494806e-01
## x20MCx1673  2.956331e-01 -0.2712116429  1.873875e-02  1.508867e-01
## x20MCx1708 -4.565084e-02  0.0747402412  1.139625e-01 -1.899543e-01
## x20MCx1717 -1.777271e-02  0.1319332000  3.622770e-02  1.458930e-01
## x20MCx1734 -1.007459e-01  0.0368595239  1.126979e-01  8.629172e-02
## x20MCx1756 -5.851726e-02  0.0757754795  9.286933e-02 -1.617091e-01
## x20MCx1780  3.288275e-01 -0.2124255800  2.666467e-02  5.250735e-02
## x20MCx1790 -2.949684e-01 -0.0660422839 -8.039292e-02  7.122191e-02
## x20MCx1830  3.633881e-01 -0.3690758346  3.173482e-02  2.008274e-02
## x20MCx1837 -3.108071e-01 -0.0321971435 -8.798549e-02  9.970680e-02
## x20MCx1854 -2.411459e-01  0.0202886456 -2.098401e-02  8.540950e-02
## x20MCx1868 -1.633337e-01  0.0750882331  6.679363e-02  6.731169e-02
## x20MCx1871  3.528713e-01  0.0421299025 -5.467655e-02 -9.626565e-02
## x20MCx1925 -1.682029e-01 -0.0258849759  7.926665e-02 -1.825150e-01
## x20MCx1941 -1.324606e-01  0.1301864268  8.592361e-02  6.446464e-02
## x20MCx1959  2.438889e-01  0.2630517349 -2.493008e-01 -6.333559e-03
## x20MCx1986 -7.162017e-02 -0.0282832696  6.960484e-02 -6.807642e-02
## x20MCx2000 -3.177201e-01 -0.0618778472 -1.186698e-01  8.531650e-02
## x20MCx2016  5.638573e-02  0.0019839989  1.294225e-01 -1.236357e-01
## x20MCx2024 -1.964024e-03  0.0279114410  1.259064e-01 -1.339170e-01
## x20MCx2039  4.432708e-03  0.0066726308  1.117932e-01 -4.030838e-02
## x20MCx2085 -3.183601e-01 -0.0464139208 -1.272263e-01  3.823604e-02
## x20MCx2118 -1.573804e-01  0.0006767895  1.756657e-02  3.301254e-02
## x20MCx2119  2.254877e-02  0.1185811873  7.614810e-02  2.315938e-02
## x20MCx2233  3.506494e-02 -0.1144489407  3.386538e-02 -2.737705e-01
## x20MCx2251  1.381324e-01  0.2664370921  2.915118e-03  1.305244e-01
## x20MCx2265 -2.852647e-01 -0.0027850249 -5.519737e-03  1.179980e-01
## x20MCx2307  2.385800e-01 -0.0633346005  7.167520e-02 -1.103382e-01
## x20MCx2328  2.107186e-01  0.2911829243 -2.985950e-01  8.464742e-02
## x20MCx2344  3.341574e-02  0.1381756259  1.312399e-01 -6.143241e-02
## x20MCx2351 -2.459304e-01 -0.0236086966  4.747543e-02 -1.033507e-01
## x20MCx2368  2.632434e-01  0.2429018804 -1.407084e-01  2.543172e-02
## x20MCx2465 -1.866954e-01 -0.0898284398 -4.002027e-02 -2.915953e-02
## x20MCx2483 -3.448897e-01 -0.0786329708 -7.378534e-02  3.295102e-02
## x20MCx2542 -2.696400e-01 -0.0038722536 -5.706137e-04  1.127226e-01
## x20MCx2559 -2.121599e-01 -0.0126693448 -1.387796e-01  1.493590e-01
## x20MCx2581 -3.090154e-01 -0.0934755338 -2.748080e-01  1.385407e-01
## x20MCx2628 -1.328534e-02 -0.1239419272  8.059747e-02  6.201197e-03
## x20MCx2631 -1.070194e-01  0.0691393821  1.408414e-01 -7.943149e-02
## x20MCx2634  1.877275e-01  0.1425976882 -1.089295e-02 -1.336256e-01
## x20MCx2642  3.086354e-02  0.1806833675  1.570328e-01 -4.928268e-02
## x20MCx2677  1.026692e-01  0.0014558120  1.130070e-01 -1.503868e-01
## x20MCx2717  9.282637e-02 -0.0119279339  8.316684e-02 -1.407206e-01
## x20MCx2745  2.042029e-01 -0.3507432821  4.449727e-02  1.922014e-01
## x20MCx2759 -1.246624e-01  0.0016626659  9.414210e-02 -7.824774e-02
## x20MCx2761 -2.377080e-01  0.0207804517  4.287395e-02  4.196873e-02
## x20MCx2773 -2.155266e-01  0.0315041991  5.869699e-02  5.755256e-02
## x20MCx2787 -1.282589e-01  0.0114380137  1.305097e-01 -5.948223e-02
## x20MCx2857  1.045150e-01 -0.3455689998  7.367462e-02  9.829729e-02
## x20MCx2870 -2.064080e-01 -0.0009000548  6.294910e-02 -1.716737e-02
## x20MCx2885 -8.614574e-02  0.0422118603  6.746159e-02  7.785939e-02
## x20MCx2895  1.628070e-01 -0.0180420122  8.766104e-02 -2.229004e-02
## x20MCx2896  2.016840e-01 -0.1946186426  1.228161e-01 -1.773113e-02
## x20MCx2929 -3.236372e-01 -0.0638217812 -1.452424e-01  1.001671e-01
## x20MCx2969 -9.021998e-02  0.1180850800  1.479332e-01 -3.170477e-02
## x20MCx2975 -3.178088e-01 -0.0662631842 -1.451708e-02  3.253881e-03
## x20MCx2988 -1.980793e-01  0.0696394356  3.501763e-02  1.539288e-01
## x20MCx3020 -3.261185e-01 -0.0439703858 -1.566557e-01  1.366822e-01
## x20MCx3044  1.063013e-01  0.0385128717  1.006915e-01 -8.330332e-02
## x20MCx3048 -1.557541e-01 -0.0342524439  1.015264e-01 -3.888004e-02
## x20MCx3094 -1.802646e-01  0.0801518342  2.645822e-02  1.834783e-01
## x20MCx3099 -1.816103e-01 -0.0252713017  7.373230e-02 -1.653695e-01
## x20MCx3108 -2.293905e-01 -0.0226776473 -4.871203e-02 -6.095355e-02
## x20MCx3119  1.449913e-01 -0.1022894086  1.196512e-01 -9.422611e-02
## x20MCx3228 -2.524877e-01 -0.0191744804  9.501077e-05 -5.660431e-03
## x20MCx3241 -1.292114e-01  0.0544367206  2.930707e-02 -1.367787e-02
## x20MCx3308 -4.268323e-02  0.1027523366  9.487367e-02  3.095527e-02
## x20MCx3335 -1.278600e-01  0.0870072654  9.647420e-02 -2.437462e-02
## x20MCx3337 -8.619709e-02  0.0726602905  1.389277e-01 -1.054655e-01
## x20MCx3402  1.326968e-01  0.0899848799  3.192417e-02  1.973065e-01
## x30MCx1112 -2.337516e-01 -0.0098831798 -2.218336e-02  1.100224e-01
## x30MCx1116  2.915365e-01 -0.0248261590 -8.127323e-03 -2.065421e-01
## x30MCx1163  1.926921e-01 -0.0652718272  1.407057e-01 -7.737540e-02
## x30MCx1170  1.005357e-01  0.1244708862  9.431344e-02  2.558964e-02
## x30MCx1172 -2.381966e-01  0.0404185198  6.424891e-02  7.304682e-02
## x30MCx1180 -2.071636e-01  0.0563334763  2.211256e-02  1.299007e-01
## x30MCx1193  2.056511e-01  0.1799325937 -3.957923e-02 -6.916471e-02
## x30MCx1196 -2.770973e-02  0.1636416668  6.694851e-02  5.425521e-03
## x30MCx1201  2.357501e-01  0.0526898497  1.037211e-01  2.267477e-02
## x30MCx1226 -3.670400e-02  0.1553684559  8.944300e-02 -6.643271e-02
## x30MCx1235 -1.865706e-01  0.0274903720  1.394763e-01 -1.077443e-02
## x30MCx1259  1.341667e-01  0.0057660957  1.451639e-01  3.500567e-02
## x30MCx1266  2.721548e-01  0.2939329808 -3.521925e-01  4.631574e-03
## x30MCx1270 -6.573673e-02  0.0557685750  1.228777e-01 -1.351356e-01
## x30MCx1280  1.780587e-02  0.2444069561 -9.155435e-02  2.204626e-01
## x30MCx1308 -1.413721e-05  0.1372514299  7.920877e-02 -1.154823e-01
## x30MCx1314  3.060545e-01 -0.0228007097  4.083877e-02 -4.860262e-02
## x30MCx1321  3.430202e-01 -0.0313517931  4.271626e-02  2.724411e-02
## x30MCx1335 -8.322347e-03  0.0992686498  1.218161e-01 -3.437378e-02
## x30MCx1394 -3.218630e-01 -0.1224497657 -1.694082e-01  4.129610e-02
## x30MCx1405  1.695967e-02  0.0858175183  1.205917e-01 -2.593962e-01
## x30MCx1415 -1.133152e-01  0.1743084260  5.606310e-02  1.402878e-01
## x30MCx1417 -2.992177e-02  0.1384675318  1.089514e-01  1.711547e-02
## x30MCx1451  2.867186e-01  0.1593867455 -5.059165e-02 -1.061060e-01
## x30MCx1479  1.332191e-01 -0.3921051211  1.677282e-02 -6.934654e-02
## x30MCx1503 -2.848931e-02  0.1506848180  7.605298e-02  6.316057e-02
## x30MCx1517 -2.802405e-01 -0.1093224658 -1.275844e-01 -1.317219e-01
## x30MCx1527  1.888569e-01 -0.2060087563  1.164165e-01  2.381744e-03
## x30MCx1556  8.079266e-02  0.1731465580  1.146591e-01 -5.977953e-02
## x30MCx1566 -3.694788e-02 -0.0018591436  1.125272e-01 -1.839529e-01
## x30MCx1569 -5.965710e-02  0.1519967378  1.191372e-01  8.723414e-03
## x30MCx1586 -5.689898e-02  0.1476725687  1.020674e-01  5.227447e-02
## x30MCx1592  8.868882e-02  0.0758223690  5.329796e-02 -3.389544e-02
## x30MCx1597 -8.354773e-02  0.0695405507  1.218025e-01 -1.119821e-01
## x30MCx1601  2.791904e-01 -0.2466808398  8.564845e-02  1.310767e-01
## x30MCx1611  3.084881e-02  0.0958359489  1.270770e-01 -1.016853e-01
## x30MCx1618  2.761274e-01 -0.2412284470  9.965882e-02  1.310928e-01
## x30MCx1636  3.656938e-01  0.1066330028 -1.442218e-01 -4.861615e-02
## x30MCx1637  3.047453e-01 -0.1577574189  8.994741e-02  9.134448e-02
## x30MCx1646  1.458748e-01  0.1791838893  4.229553e-02 -9.207664e-02
## x30MCx1649  1.302877e-01  0.2391266598  6.768472e-03  1.115335e-01
## x30MCx1664 -1.174819e-01  0.0976577529  1.240381e-01  1.127585e-01
## x30MCx1712  6.824434e-02  0.1862611426  6.468723e-02  9.070190e-02
## x30MCx1722 -1.778526e-01  0.1041321044  3.810525e-02  1.706352e-01
## x30MCx1744  1.389449e-01  0.1557201133  1.004629e-01 -4.620910e-03
## x30MCx1748 -1.431104e-01  0.1012955303  9.644100e-02  1.089483e-01
## x30MCx1774  3.470470e-01  0.0272802417  4.740122e-03 -5.208317e-02
## x30MCx1782  2.617637e-01  0.0681929679  9.588955e-03  5.826291e-02
## x30MCx1786 -2.526616e-01 -0.0309980483  4.006633e-02 -1.892103e-02
## x30MCx1787  3.276127e-02 -0.0576911707  1.283687e-01 -9.644152e-02
## x30MCx1791  2.411004e-01  0.1897479991 -1.658290e-01 -1.773644e-01
## x30MCx1792 -5.307368e-02  0.1465175204  7.372842e-02  7.562589e-02
## x30MCx1824  9.866621e-02  0.0822573491  8.973850e-02 -8.205701e-02
## x30MCx1828  9.446183e-03  0.2257462098  7.707629e-02  3.504152e-02
## x30MCx1860  3.487425e-01 -0.0234982432  3.457939e-02 -2.680176e-03
## x30MCx1872  1.495132e-01  0.1749077399  3.823041e-02 -1.987114e-01
## x30MCx1881 -1.451589e-01 -0.0116944979  9.180696e-02 -1.494256e-01
## x30MCx1911  1.681550e-01 -0.3625243388  6.373900e-02 -4.052763e-02
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## x30MCx1966 -9.169906e-02  0.1332292086  1.110018e-01  5.565084e-02
## x30MCx1972  3.774723e-01 -0.1742154017 -2.085074e-02 -7.794090e-02
## x30MCx1980  2.749238e-01 -0.2888161051  6.210341e-02  1.018294e-01
## x30MCx1993  1.781594e-01  0.1303820733  2.213639e-02 -1.780804e-01
## x30MCx1996 -1.245782e-01  0.1177118998  8.616333e-02  7.036543e-02
## x30MCx2009 -1.057602e-01  0.0964403702  1.158718e-01  8.820388e-03
## x30MCx2015  2.165877e-01  0.0931431277 -4.823444e-01 -4.435008e-02
## x30MCx2022  3.260504e-01  0.1709823254 -1.315257e-01 -1.091994e-01
## x30MCx2041  2.134717e-01  0.2943908230 -8.753271e-02  4.293945e-02
## x30MCx2081  9.065584e-02  0.2033797249  1.063905e-01 -7.833548e-02
## x30MCx2092 -2.551779e-01  0.0191033365  2.516869e-03  1.867799e-01
## x30MCx2096 -1.030650e-03  0.0550460741  4.546905e-02 -2.184783e-01
## x30MCx2099  1.149575e-01  0.1927340631  1.258577e-01 -3.534625e-02
## x30MCx2107  4.225642e-02  0.1940260716 -1.058854e-02 -1.806474e-02
## x30MCx2131 -2.449188e-01 -0.0618801108  5.539360e-02 -1.124078e-01
## x30MCx2132 -7.586416e-02  0.0985406730  1.171685e-01  4.547167e-02
## x30MCx2140  2.722765e-01  0.1019580315  2.156025e-02  1.791476e-02
## x30MCx2149  2.197173e-01  0.0461751891  6.660731e-02  1.812629e-02
## x30MCx2158  6.845965e-02  0.1556858246  5.702319e-02  1.576955e-01
## x30MCx2166  2.115466e-01  0.2609655511 -3.497018e-02 -5.561415e-02
## x30MCx2168  1.394120e-01  0.3017369197 -6.980313e-02  7.065749e-02
## x30MCx2179 -5.277540e-02 -0.0748687256  1.179076e-01 -2.232629e-01
## x30MCx2183 -9.556383e-02  0.0170970081  1.386449e-01 -4.101485e-02
## x30MCx2201  2.583958e-02  0.1787936044  8.506021e-02 -7.151611e-02
## x30MCx2204  2.658773e-01 -0.3254561858  3.082051e-02  1.769963e-01
## x30MCx2206 -2.625223e-01  0.0101042781 -5.525251e-02  1.851810e-01
## x30MCx2257  1.762014e-01  0.0738396538  9.595658e-02 -3.770455e-02
## x30MCx2281  2.785795e-01  0.2396203140 -1.282026e-01 -4.959767e-02
## x30MCx2298  6.674375e-02  0.1860658929  1.620186e-02  1.135349e-01
## x30MCx2312  7.919491e-02  0.2433701245  5.285661e-02  2.106915e-02
## x30MCx2316  9.998196e-02  0.3074631323  1.585971e-02  1.131346e-01
## x30MCx2327  7.160383e-02  0.2334614139  7.461961e-02 -3.667001e-02
## x30MCx2334  1.001411e-02  0.1856698200  1.205443e-01  2.451521e-02
## x30MCx2349 -2.169121e-01  0.0576246442  4.648463e-02  2.110586e-02
## x30MCx2352 -1.949978e-01  0.0633664263  4.903186e-02  7.595587e-02
## x30MCx2353  2.927519e-01  0.1360535170 -2.301052e-02 -1.331825e-01
## x30MCx2354 -1.442512e-01  0.0411758791  6.664666e-02  4.037951e-02
## x30MCx2363 -4.050338e-02  0.1158614228  9.563957e-02  1.814773e-02
## x30MCx2414  7.023401e-02  0.1299993314 -3.127684e-02 -1.044060e-01
## x30MCx2415  2.118482e-01  0.1145050218  6.334289e-02 -7.254314e-02
## x30MCx2423  2.790731e-01 -0.0905813742  1.170185e-01  1.001016e-02
## x30MCx2425 -5.260545e-02  0.0805856754  1.178515e-01  2.071310e-02
## x30MCx2445  2.647446e-01  0.2924475996 -2.028964e-01  3.091194e-03
## x30MCx2450  5.214202e-02 -0.2766385619  7.232517e-02  1.855730e-02
## x30MCx2451 -2.579073e-01  0.0609986475 -7.998818e-02  1.872401e-01
## x30MCx2473 -1.357540e-01  0.0810727307  1.155809e-01  1.003241e-01
## x30MCx2480 -2.246410e-02  0.0045898564  8.833661e-03 -1.692346e-01
## x30MCx2499 -2.632099e-02  0.1133704038  1.203560e-01 -5.301855e-02
## x30MCx2501  2.258319e-01 -0.0166049996  8.896872e-02 -6.407161e-02
## x30MCx2529  2.401325e-01  0.0425568910 -1.780679e-02 -1.982945e-01
## x30MCx2543 -1.354939e-01  0.0773168961  1.282813e-01  6.184080e-03
## x30MCx2568  2.774640e-01 -0.0860621882  1.174801e-01  1.152385e-01
## x30MCx2570 -1.698904e-01  0.0697115839  8.161576e-02  1.412771e-01
## x30MCx2573  1.644161e-01  0.2507144782  9.109352e-03 -1.274170e-01
## x30MCx2574 -6.718774e-02  0.1027874633  6.883749e-02 -6.348395e-02
## x30MCx2605  1.087542e-02  0.0760997770  5.036429e-02 -4.868906e-02
## x30MCx2619  7.650914e-02  0.1079455474  9.386578e-02  1.933651e-02
## x30MCx2654  3.958029e-01 -0.3772610703 -3.869683e-02  1.229408e-01
## x30MCx2661 -1.791754e-02  0.1497166691 -1.473450e-02  1.736448e-01
## x30MCx2662  6.009063e-02  0.2351588838  7.248778e-02 -7.798354e-03
## x30MCx2675 -3.366727e-03 -0.0780107774  1.649004e-01 -4.502539e-02
## x30MCx2676  1.014057e-01  0.0765957477  2.072755e-02  1.170347e-02
## x30MCx2700  3.652733e-02  0.1890219616  1.341956e-01 -2.030894e-02
## x30MCx2708 -2.036127e-01 -0.0160187535  5.621458e-02 -1.357601e-02
## x30MCx2720  2.123223e-01  0.2825640856 -7.900700e-02  7.067759e-02
## x30MCx2735 -1.711076e-01  0.0717085021  8.757055e-02 -1.032914e-02
## x30MCx2746  1.309631e-01  0.1710119369  8.303831e-02 -8.989857e-02
## x30MCx2760 -7.487674e-02  0.0971551464  1.420943e-01 -8.793684e-02
## x30MCx2770 -5.779742e-02 -0.1376142438  3.360178e-02 -1.852845e-01
## x30MCx2775 -2.316608e-01 -0.0045143434  9.906931e-02 -6.175262e-02
## x30MCx2777  5.439015e-02  0.1467819016  1.222783e-01 -6.564676e-02
## x30MCx2783  1.023269e-01  0.2478518938 -3.088520e-02  1.478028e-02
## x30MCx2790  4.680325e-04  0.1601142330  1.492143e-01  2.874537e-02
## x30MCx2811  1.826216e-01  0.1853494430  1.426860e-02 -8.562133e-02
## x30MCx2819  2.731482e-01  0.2617973360 -2.885601e-01 -6.804420e-02
## x30MCx2822 -1.235120e-01  0.1315652183  3.908400e-02  1.942718e-01
## x30MCx2828 -4.858164e-04  0.1360069808  9.386088e-02 -1.914720e-02
## x30MCx2840  3.664889e-01 -0.0397805384 -1.871400e-01 -1.463773e-01
## x30MCx2881 -8.873962e-02  0.0210734949 -7.126503e-03  2.169240e-01
## x30MCx2909  3.360475e-01  0.1709060851 -1.573392e-01 -1.019368e-01
## x30MCx2911 -2.073708e-01  0.0578039357  9.810644e-02  5.501711e-02
## x30MCx2920  3.156600e-01 -0.3361632428  3.212047e-02  9.883386e-02
## x30MCx2941 -1.293760e-01  0.0154802013  1.086682e-01 -1.295039e-01
## x30MCx2954  3.585652e-02  0.0794656446  7.329931e-02 -7.806787e-02
## x30MCx2966 -2.834713e-02  0.1109063314  1.500784e-01 -6.825682e-02
## x30MCx2990 -5.716088e-02  0.0559489510  1.254436e-01 -9.514876e-02
## x30MCx2995 -1.130271e-01  0.1637731511  7.605033e-02  1.033256e-01
## x30MCx3000 -5.772087e-02  0.0721047209  1.469379e-01  1.826675e-02
## x30MCx3017  2.657787e-01 -0.2691193130  7.481016e-02  1.609549e-01
## x30MCx3025 -1.268308e-01  0.1187026744 -3.139472e-03  1.785206e-01
## x30MCx3030 -5.957602e-02  0.1017624871  1.403837e-01  2.114558e-02
## x30MCx3058  2.860152e-01 -0.3311987093  2.616811e-02  1.804975e-01
## x30MCx3061 -1.205224e-01  0.1213912203  8.068211e-02  5.911353e-02
## x30MCx3065 -4.562828e-02  0.0548621015  1.075297e-01 -2.028505e-01
## x30MCx3070 -2.406511e-01  0.0589833473  3.835713e-02  1.791855e-01
## x30MCx3083  1.782641e-01  0.1171398460  1.484865e-02  9.292536e-03
## x30MCx3086 -1.565791e-01  0.0876924360  1.196299e-01  9.035875e-02
## x30MCx3091  1.481139e-02  0.1609069952  9.999432e-02 -8.597909e-02
## x30MCx3100  2.116347e-01  0.1446778135 -5.975116e-02 -2.191576e-01
## x30MCx3103  2.418326e-01  0.2294489160 -1.503768e-01 -6.602376e-02
## x30MCx3118  2.940874e-02  0.2455598642  2.106532e-02  7.173693e-02
## x30MCx3128  1.986449e-01  0.1359648348 -5.506149e-02  8.799329e-03
## x30MCx3140 -2.161659e-02  0.0238937975  5.492102e-02  1.510871e-01
## x30MCx3152 -1.982004e-01  0.0429559046  7.145249e-02  4.585506e-02
## x30MCx3160  3.125754e-01  0.1110789836 -4.559244e-01 -2.758517e-02
## x30MCx3171 -1.797873e-01  0.0014870174  7.603300e-02 -3.716739e-02
## x30MCx3180 -4.749519e-02  0.1335681173  1.609858e-01  2.572500e-02
## x30MCx3183  1.455103e-01  0.1582721690  4.466246e-02 -8.669530e-02
## x30MCx3214 -1.567019e-01  0.0908024623  8.498732e-02  9.202861e-02
## x30MCx3221 -1.377968e-01  0.0344875505  1.250554e-01  2.034148e-02
## x30MCx3237 -4.391824e-02  0.1135259760  1.066799e-01  7.915911e-03
## x30MCx3240  3.865386e-01 -0.3008220060 -3.235251e-02  1.020692e-01
## x30MCx3243  2.925481e-01 -0.3295174896  6.409890e-03  1.908107e-01
## x30MCx3263 -1.634778e-01  0.0380117063 -2.139277e-02  9.812411e-02
## x30MCx3291  1.154846e-01  0.1708544402  8.527318e-02 -7.753267e-02
## x30MCx3314  2.313942e-01  0.2154663564 -4.504003e-01 -1.064306e-02
## x30MCx3340  4.230110e-02  0.1817419080  9.134844e-02  5.832325e-02
## x30MCx3345  1.681634e-01  0.0984466959  8.894086e-02 -3.908235e-02
## x30MCx3366  4.795253e-03  0.0606194361  1.246211e-01 -1.816598e-01
## x30MCx3369  3.376410e-01  0.1351483415 -7.059304e-02  7.838748e-02
## x30MCx3375 -2.173919e-01  0.0162319916  4.568285e-02 -4.635593e-02
## x30MCx3376 -5.053873e-03  0.1277127540  1.573244e-01 -6.953982e-02
## x30MCx3379 -1.699398e-01 -0.0271477365  9.858485e-02 -1.905833e-01
## x30MCx3384  3.719974e-01 -0.1475632441 -6.128495e-03  9.812971e-03
## x30MCx3414  3.110982e-01 -0.2257031908  9.950901e-02  9.929551e-02
## x10MCx1135  2.851446e-01 -0.3818553120  7.393129e-03  9.141695e-02
## x10MCx1140 -1.898279e-01  0.0127473248  5.887320e-02 -8.381314e-03
## x10MCx1144 -2.395494e-01 -0.0679633402 -2.584903e-01  1.644396e-01
## x10MCx1155  3.573786e-01 -0.1304424117 -7.833319e-02 -2.250763e-02
## x10MCx1165 -1.636675e-01 -0.0143234205  7.229247e-02  1.974216e-02
## x10MCx1208 -2.505135e-01 -0.0356035314 -4.050462e-03  6.906911e-02
## x10MCx1229 -2.694503e-01 -0.1273402067 -1.512617e-01  3.834019e-02
## x10MCx1256 -7.760788e-02 -0.0247813408  1.005229e-01 -1.253778e-01
## x10MCx1273  1.978982e-01 -0.3090405564  5.271025e-02  2.022921e-01
## x10MCx1291 -8.233427e-02  0.0730791699  5.956112e-02  1.639608e-02
## x10MCx1318 -1.711139e-01 -0.0023124002  7.297610e-02 -1.050413e-01
## x10MCx1330 -2.679246e-01 -0.0365159827 -5.943522e-02  4.642228e-02
## x10MCx1333  1.810244e-01 -0.3150921485  7.170514e-02  1.691234e-01
## x10MCx1344  2.483113e-02  0.0196274988  6.720109e-02 -1.469352e-01
## x10MCx1365  8.192654e-03  0.2049684064  5.258251e-02  1.732728e-01
## x10MCx1395  1.133976e-01 -0.0067110746  1.280732e-01 -7.772398e-02
## x10MCx1414  9.150657e-02  0.0664191031  5.869176e-02 -1.570013e-01
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## x10MCx1450 -2.174843e-01 -0.0133935892  1.107884e-01 -1.076414e-02
## x10MCx1494 -2.485070e-01 -0.0554606160 -4.924153e-03  4.748853e-02
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## x10MCx1633  7.281002e-02 -0.0287502766  8.611558e-02 -5.001008e-02
## x10MCx1643 -1.363111e-01  0.0479728957  2.694272e-02  1.121506e-01
## x10MCx1668 -3.086047e-01 -0.0378810224 -3.678849e-02  1.316674e-01
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## x10MCx1685 -1.444853e-03 -0.0142747306  1.213896e-01 -5.474646e-02
## x10MCx1755  2.663735e-01  0.2455047286 -3.832968e-01  4.061828e-03
## x10MCx1778 -2.795973e-02  0.1134617262  1.553417e-01 -3.890125e-02
## x10MCx1785 -2.817790e-01 -0.0516970501 -1.055576e-01  1.457743e-01
## x10MCx1859 -2.518664e-01 -0.0266788790 -1.480161e-01  1.061287e-01
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## x10MCx1946 -1.789122e-01  0.0287428921  3.035541e-02  4.219370e-02
## x10MCx2003  6.036406e-02  0.0162828702  8.490554e-02 -1.961931e-02
## x10MCx2012 -8.537195e-02  0.1909307604 -7.309506e-02  2.990513e-01
## x10MCx2028 -1.086672e-01  0.0214626808  1.332532e-01 -5.542276e-02
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##                     [,5]
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## x10MCx3287  3.055781e-02
## x10MCx3318 -2.818984e-02
## x10MCx3322  7.657179e-02
## x11MCx1159 -6.451732e-02
## x11MCx1329 -9.125958e-02
## x11MCx1383 -2.935406e-02
## x11MCx1533 -7.191005e-02
## x11MCx1588 -1.560842e-01
## x11MCx1751  2.537964e-02
## x11MCx1874  1.773752e-02
## x11MCx1923 -1.068885e-01
## x11MCx2191 -5.979784e-02
## x11MCx2264 -7.784715e-02
## x11MCx2302 -1.265819e-01
## x11MCx2379 -9.153987e-02
## x11MCx2402 -9.020626e-02
## x11MCx2511  1.704041e-01
## x11MCx2539  1.143296e-01
## x11MCx2713 -1.237205e-01
## x11MCx2768 -3.671270e-02
## x11MCx2847 -6.341756e-02
## x11MCx2889 -1.196629e-01
## x11MCx2897 -6.957774e-02
## x11MCx2957 -9.621265e-03
## x11MCx3134 -2.519767e-02
## x11MCx3181  5.367005e-02
## x11MCx3193 -1.216956e-02
## x11MCx3248 -5.531811e-02
## x11MCx3265 -8.133782e-02
## x12MCx1189  1.272330e-01
## x12MCx1202 -1.090470e-01
## x12MCx1212  1.402038e-02
## x12MCx1237  2.609175e-02
## x12MCx1242  4.116896e-02
## x12MCx1244 -9.356015e-02
## x12MCx1289 -1.247934e-01
## x12MCx1320 -4.227137e-02
## x12MCx1347  4.117311e-02
## x12MCx1353  1.263883e-01
## x12MCx1356  1.688757e-02
## x12MCx1368 -3.405713e-02
## x12MCx1377 -1.018532e-01
## x12MCx1392 -6.226175e-03
## x12MCx1426 -3.226577e-02
## x12MCx1446  1.410676e-02
## x12MCx1480  5.559222e-02
## x12MCx1519 -1.675178e-02
## x12MCx1639 -8.393866e-02
## x12MCx1642 -1.468087e-01
## x12MCx1651 -1.126839e-01
## x12MCx1652 -5.544725e-03
## x12MCx1672  2.755197e-02
## x12MCx1719  1.191459e-01
## x12MCx1738  7.346059e-02
## x12MCx1749 -2.571741e-02
## x12MCx1771  1.907339e-02
## x12MCx1788 -3.979860e-03
## x12MCx1836 -8.478907e-02
## x12MCx1869 -3.339613e-02
## x12MCx1886 -3.247638e-03
## x12MCx1893  3.426078e-02
## x12MCx1895 -8.701835e-02
## x12MCx1903 -3.446994e-02
## x12MCx1909 -6.805542e-02
## x12MCx1922 -6.827990e-02
## x12MCx1988  3.198177e-02
## x12MCx2002  1.312499e-01
## x12MCx2109  1.049078e-01
## x12MCx2111  4.916028e-04
## x12MCx2136 -5.212508e-02
## x12MCx2185  1.104665e-01
## x12MCx2202  1.018928e-01
## x12MCx2212  1.358789e-01
## x12MCx2259 -4.224763e-02
## x12MCx2291  6.020213e-02
## x12MCx2317 -6.091528e-02
## x12MCx2321  7.962496e-02
## x12MCx2323 -1.635322e-01
## x12MCx2347  5.558494e-02
## x12MCx2380  1.712423e-01
## x12MCx2454  6.118780e-02
## x12MCx2489  5.638739e-02
## x12MCx2496  4.654846e-02
## x12MCx2522 -5.930256e-02
## x12MCx2530 -5.381232e-02
## x12MCx2576  7.307098e-02
## x12MCx2667 -1.158287e-01
## x12MCx2701  9.563572e-02
## x12MCx2736 -2.860940e-02
## x12MCx2763  1.759320e-02
## x12MCx2778  5.730105e-02
## x12MCx2798  1.183337e-01
## x12MCx2849 -1.922018e-02
## x12MCx2993 -1.242952e-01
## x12MCx3006 -2.469202e-02
## x12MCx3026 -1.492292e-01
## x12MCx3046 -4.068219e-02
## x12MCx3072 -5.237724e-02
## x12MCx3082 -2.077126e-01
## x12MCx3113 -5.717883e-02
## x12MCx3117 -7.231837e-02
## x12MCx3125 -2.219441e-01
## x12MCx3230  1.105410e-01
## x12MCx3272 -4.034401e-02
## x12MCx3333 -6.483136e-02
## x12MCx3342  2.170913e-02
## x12MCx3344  6.336011e-02
## x12MCx3380  8.702729e-02
## x12MCx3392 -6.961801e-02
## x12MCx3424 -4.125321e-03
## x13MCx1175  2.062482e-02
## x13MCx1231  2.591983e-02
## x13MCx1299 -5.942008e-02
## x13MCx1419 -2.655322e-03
## x13MCx1506 -4.638747e-02
## x13MCx1608  1.884890e-02
## x13MCx1783 -5.428858e-02
## x13MCx1887 -6.750711e-02
## x13MCx2071  1.138503e-02
## x13MCx2129  1.142505e-01
## x13MCx2229 -5.914715e-02
## x13MCx2582 -3.944343e-02
## x13MCx3092  8.902828e-02
## x13MCx3274 -8.415704e-03
## x13MCx3399 -2.444279e-02
## x14MCx1338  3.997970e-03
## x14MCx2102  1.291826e-01
## x14MCx2548  8.898195e-04
## x14MCx2875  6.453747e-02
## x30MCx1130  4.624100e-02
## x30MCx1137 -1.732463e-01
## x30MCx1169  5.105771e-02
## x30MCx1183 -1.043606e-01
## x30MCx1188 -1.689024e-02
## x30MCx1195 -6.578183e-02
## x30MCx1197  8.857469e-02
## x30MCx1199 -1.887243e-02
## x30MCx1204 -1.675739e-02
## x30MCx1210 -1.222162e-02
## x30MCx1214  5.435169e-02
## x30MCx1217  1.262306e-02
## x30MCx1248 -6.837628e-02
## x30MCx1253  8.696507e-02
## x30MCx1262  5.806832e-02
## x30MCx1271 -1.578755e-01
## x30MCx1276  8.137388e-02
## x30MCx1293  1.225424e-01
## x30MCx1296 -4.173320e-03
## x30MCx1312  6.454044e-02
## x30MCx1331 -8.617838e-02
## x30MCx1346  1.187660e-01
## x30MCx1358 -1.000767e-01
## x30MCx1370 -8.204931e-02
## x30MCx1371  2.521423e-02
## x30MCx1372  1.540780e-02
## x30MCx1380  1.199377e-01
## x30MCx1400 -1.273813e-01
## x30MCx1401 -1.381510e-02
## x30MCx1406  7.828911e-05
## x30MCx1423 -3.743254e-03
## x30MCx1425  1.003749e-01
## x30MCx1430 -4.008739e-02
## x30MCx1449  4.954943e-02
## x30MCx1452 -2.981223e-02
## x30MCx1461  1.806227e-01
## x30MCx1474 -5.894408e-02
## x30MCx1477 -2.309211e-02
## x30MCx1509  2.884365e-02
## x30MCx1522 -1.559855e-02
## x30MCx1524 -1.021473e-01
## x30MCx1525  3.513010e-02
## x30MCx1544  1.233269e-01
## x30MCx1554 -7.920781e-02
## x30MCx1573 -1.004181e-01
## x30MCx1575 -6.241126e-02
## x30MCx1590  1.439634e-01
## x30MCx1594 -1.038231e-01
## x30MCx1607 -1.461458e-01
## x30MCx1609  1.824351e-02
## x30MCx1644  1.495243e-02
## x30MCx1662 -3.938116e-03
## x30MCx1674  2.854088e-03
## x30MCx1682  4.632064e-03
## x30MCx1683  8.823187e-02
## x30MCx1686  5.415173e-02
## x30MCx1688 -3.805373e-02
## x30MCx1691 -2.236943e-02
## x30MCx1696 -5.443122e-02
## x30MCx1707 -1.433427e-02
## x30MCx1741 -6.238789e-02
## x30MCx1750  4.820415e-03
## x30MCx1754  6.801150e-02
## x30MCx1761 -1.263473e-01
## x30MCx1762 -9.370365e-02
## x30MCx1765 -3.462589e-02
## x30MCx1767  1.090050e-02
## x30MCx1779 -4.113762e-03
## x30MCx1796 -4.490386e-03
## x30MCx1813  4.467296e-02
## x30MCx1832  4.465755e-02
## x30MCx1838  8.228159e-02
## x30MCx1840  1.002513e-01
## x30MCx1851 -2.679598e-02
## x30MCx1852 -6.991869e-02
## x30MCx1856 -2.790108e-03
## x30MCx1885 -1.818440e-02
## x30MCx1902 -1.791245e-02
## x30MCx1919  8.031778e-02
## x30MCx1924  1.401620e-01
## x30MCx1930  3.811160e-02
## x30MCx1935 -1.117163e-01
## x30MCx1938  1.485169e-01
## x30MCx1942  3.741623e-02
## x30MCx1956 -1.916628e-01
## x30MCx1957  1.165109e-01
## x30MCx1969 -5.053282e-02
## x30MCx1975 -1.772944e-01
## x30MCx1976  9.799474e-02
## x30MCx1987  2.035093e-01
## x30MCx1990 -1.035024e-02
## x30MCx2004 -2.018560e-01
## x30MCx2020  4.699452e-02
## x30MCx2023  9.081154e-02
## x30MCx2052  3.560466e-03
## x30MCx2065  8.539347e-02
## x30MCx2075  6.398430e-02
## x30MCx2080 -8.846243e-03
## x30MCx2082 -5.392758e-02
## x30MCx2089 -6.904974e-02
## x30MCx2116  1.466758e-01
## x30MCx2121 -6.009122e-03
## x30MCx2128  7.352017e-02
## x30MCx2137  1.753130e-02
## x30MCx2154  5.694082e-02
## x30MCx2156  1.038270e-02
## x30MCx2164  7.454794e-02
## x30MCx2165  4.775814e-02
## x30MCx2180  3.616956e-02
## x30MCx2181 -1.207798e-01
## x30MCx2197  2.644229e-02
## x30MCx2222 -4.573963e-02
## x30MCx2226 -2.676695e-02
## x30MCx2241  8.381455e-02
## x30MCx2255 -4.017920e-02
## x30MCx2261  1.343143e-01
## x30MCx2280 -3.187575e-02
## x30MCx2303 -5.989105e-02
## x30MCx2308  4.851750e-02
## x30MCx2314 -8.733763e-02
## x30MCx2318 -1.127977e-01
## x30MCx2364  5.150135e-02
## x30MCx2369  1.297235e-01
## x30MCx2394 -1.861609e-01
## x30MCx2403 -9.292236e-03
## x30MCx2410  4.949507e-02
## x30MCx2418  1.722983e-01
## x30MCx2432 -1.294530e-01
## x30MCx2434  7.142138e-02
## x30MCx2488 -4.731180e-02
## x30MCx2512 -5.029420e-02
## x30MCx2515 -1.324117e-02
## x30MCx2516 -1.577903e-01
## x30MCx2532 -2.117437e-03
## x30MCx2549 -5.225926e-02
## x30MCx2554  1.339794e-02
## x30MCx2558  2.290466e-02
## x30MCx2567  9.960429e-02
## x30MCx2584  3.315013e-02
## x30MCx2586  1.003645e-01
## x30MCx2592  1.016502e-01
## x30MCx2595  3.481563e-02
## x30MCx2618  2.642574e-02
## x30MCx2648 -5.518354e-02
## x30MCx2656  2.719302e-02
## x30MCx2671 -9.210459e-02
## x30MCx2684 -1.176937e-01
## x30MCx2690  1.103220e-01
## x30MCx2715 -4.473414e-02
## x30MCx2719  1.304734e-01
## x30MCx2723  4.611519e-02
## x30MCx2724 -2.134901e-03
## x30MCx2727 -6.276305e-02
## x30MCx2731  1.920576e-01
## x30MCx2774  1.699632e-01
## x30MCx2780  5.229752e-02
## x30MCx2785 -7.613072e-02
## x30MCx2788  3.197827e-02
## x30MCx2792 -6.281320e-03
## x30MCx2836 -1.647936e-01
## x30MCx2837  1.449634e-01
## x30MCx2855  7.503417e-02
## x30MCx2871  2.922245e-02
## x30MCx2890 -8.208116e-02
## x30MCx2898  5.447617e-03
## x30MCx2935  4.274808e-02
## x30MCx2940 -1.298274e-01
## x30MCx2944  1.413910e-01
## x30MCx2953 -5.738224e-02
## x30MCx2956 -7.490565e-03
## x30MCx2958  6.732132e-02
## x30MCx2970 -4.823143e-02
## x30MCx2974  5.992075e-02
## x30MCx2977 -2.067403e-01
## x30MCx2982  1.155572e-01
## x30MCx2983 -4.513259e-02
## x30MCx3003 -5.366466e-02
## x30MCx3007  9.857962e-02
## x30MCx3015  6.597887e-02
## x30MCx3018 -5.079211e-02
## x30MCx3038 -5.804264e-02
## x30MCx3045  9.070833e-02
## x30MCx3053  1.712874e-01
## x30MCx3064 -2.246929e-03
## x30MCx3066  4.747831e-02
## x30MCx3087  7.334730e-02
## x30MCx3120  4.310941e-02
## x30MCx3131 -6.986150e-02
## x30MCx3137  1.180402e-02
## x30MCx3143 -1.327794e-01
## x30MCx3147 -4.723993e-02
## x30MCx3154 -4.367411e-02
## x30MCx3155  4.157467e-02
## x30MCx3161  5.844601e-02
## x30MCx3186  4.664158e-02
## x30MCx3187  6.222282e-02
## x30MCx3203  1.433942e-01
## x30MCx3208 -5.177510e-02
## x30MCx3215  1.124705e-01
## x30MCx3220 -1.466905e-02
## x30MCx3225 -9.095041e-03
## x30MCx3244 -2.216418e-02
## x30MCx3249  3.587916e-02
## x30MCx3256 -5.682062e-02
## x30MCx3259 -5.392230e-02
## x30MCx3260 -7.352929e-02
## x30MCx3270  3.477504e-02
## x30MCx3279  8.885274e-02
## x30MCx3285 -1.609704e-01
## x30MCx3297 -8.537659e-02
## x30MCx3305 -4.210662e-02
## x30MCx3353  1.740471e-01
## x30MCx3360 -1.413752e-01
## x30MCx3367 -3.139718e-02
## x30MCx3372  1.664868e-01
## x30MCx3382  2.351753e-02
## x30MCx1731  4.957941e-02
## x30MCx2868 -6.899586e-02
## x30MCx3184  3.600294e-02
## x10MCx1626 -3.470660e-02
## x10MCx2535  1.283825e-01
## x12MCx1124 -4.507913e-02
## x12MCx1288 -1.350939e-01
## x12MCx1413 -1.561646e-02
## x12MCx1528  2.694875e-02
## x12MCx1700 -4.840017e-02
## x12MCx1743 -8.996883e-02
## x12MCx2383 -7.073110e-02
## x12MCx2466  3.170264e-02
## x12MCx2493 -3.744182e-02
## x12MCx2938 -1.614861e-01
## x12MCx2996 -8.125467e-02
## x12MCx3165 -1.245910e-01
## 
## $adjusted_R2
## [1] 0.03794617
## 
## $p_value
##        value 
## 4.031883e-07 
## 
## $plot

## 
## $variance_explained
##   [1]  1.321653e-01  8.768897e-02  6.054967e-02  4.062592e-02  2.243720e-02
##   [6]  2.124238e-02  1.839077e-02  1.663625e-02  1.468250e-02  1.463041e-02
##  [11]  1.359713e-02  1.208774e-02  1.185115e-02  1.090514e-02  1.073009e-02
##  [16]  9.554333e-03  9.310788e-03  8.649744e-03  8.524363e-03  8.140948e-03
##  [21]  7.949776e-03  7.595412e-03  7.086574e-03  7.052783e-03  6.980768e-03
##  [26]  6.786125e-03  6.452960e-03  6.290318e-03  6.141058e-03  6.017337e-03
##  [31]  5.801599e-03  5.686952e-03  5.520345e-03  5.435575e-03  5.250205e-03
##  [36]  5.134178e-03  5.068075e-03  4.955526e-03  4.861919e-03  4.797168e-03
##  [41]  4.769555e-03  4.589709e-03  4.463839e-03  4.361536e-03  4.311545e-03
##  [46]  4.267369e-03  4.209128e-03  4.146562e-03  4.006638e-03  3.883306e-03
##  [51]  3.834728e-03  3.735672e-03  3.721632e-03  3.619154e-03  3.502314e-03
##  [56]  3.408902e-03  3.381116e-03  3.299189e-03  3.292854e-03  3.248227e-03
##  [61]  3.205656e-03  3.166072e-03  3.106783e-03  3.041424e-03  3.002248e-03
##  [66]  2.960244e-03  2.869361e-03  2.847727e-03  2.787567e-03  2.763870e-03
##  [71]  2.725095e-03  2.706251e-03  2.683356e-03  2.634548e-03  2.591038e-03
##  [76]  2.570126e-03  2.543298e-03  2.498802e-03  2.476136e-03  2.435465e-03
##  [81]  2.393777e-03  2.376719e-03  2.350665e-03  2.321805e-03  2.295712e-03
##  [86]  2.241228e-03  2.211121e-03  2.178051e-03  2.130243e-03  2.126878e-03
##  [91]  2.104907e-03  2.096384e-03  2.059617e-03  2.022544e-03  1.999715e-03
##  [96]  1.983476e-03  1.977991e-03  1.951854e-03  1.931020e-03  1.909067e-03
## [101]  1.874341e-03  1.867327e-03  1.842778e-03  1.822114e-03  1.801581e-03
## [106]  1.766278e-03  1.735895e-03  1.726067e-03  1.706584e-03  1.674763e-03
## [111]  1.661177e-03  1.654743e-03  1.627358e-03  1.625937e-03  1.611530e-03
## [116]  1.582598e-03  1.574382e-03  1.555702e-03  1.534379e-03  1.507453e-03
## [121]  1.498943e-03  1.466907e-03  1.459918e-03  1.442252e-03  1.430841e-03
## [126]  1.410302e-03  1.398409e-03  1.394261e-03  1.386710e-03  1.368265e-03
## [131]  1.351622e-03  1.339811e-03  1.311159e-03  1.306376e-03  1.295776e-03
## [136]  1.279019e-03  1.270461e-03  1.261099e-03  1.258824e-03  1.249767e-03
## [141]  1.239773e-03  1.225558e-03  1.215284e-03  1.207594e-03  1.184243e-03
## [146]  1.173210e-03  1.156293e-03  1.147838e-03  1.141045e-03  1.127182e-03
## [151]  1.114120e-03  1.100344e-03  1.096484e-03  1.092810e-03  1.084479e-03
## [156]  1.079324e-03  1.062818e-03  1.053117e-03  1.041248e-03  1.035072e-03
## [161]  1.015882e-03  9.986696e-04  9.898416e-04  9.837753e-04  9.800913e-04
## [166]  9.641473e-04  9.528354e-04  9.493798e-04  9.358992e-04  9.260684e-04
## [171]  9.190731e-04  9.152603e-04  9.035250e-04  8.982795e-04  8.829267e-04
## [176]  8.703151e-04  8.658380e-04  8.606865e-04  8.508813e-04  8.455104e-04
## [181]  8.384100e-04  8.204973e-04  8.165488e-04  8.116275e-04  8.045814e-04
## [186]  7.983291e-04  7.930882e-04  7.883505e-04  7.718402e-04  7.682991e-04
## [191]  7.645107e-04  7.483893e-04  7.440420e-04  7.400623e-04  7.390189e-04
## [196]  7.326484e-04  7.207423e-04  7.104842e-04  7.053825e-04  6.921625e-04
## [201]  6.864640e-04  6.796499e-04  6.761660e-04  6.723664e-04  6.635261e-04
## [206]  6.603258e-04  6.544100e-04  6.479456e-04  6.466647e-04  6.359901e-04
## [211]  6.337927e-04  6.265787e-04  6.182835e-04  6.137728e-04  6.100019e-04
## [216]  6.046203e-04  5.979360e-04  5.894522e-04  5.819774e-04  5.735109e-04
## [221]  5.676018e-04  5.591331e-04  5.561034e-04  5.531578e-04  5.493301e-04
## [226]  5.441813e-04  5.397227e-04  5.351254e-04  5.307387e-04  5.268698e-04
## [231]  5.176149e-04  5.146608e-04  5.114394e-04  5.042948e-04  4.968979e-04
## [236]  4.887396e-04  4.868140e-04  4.776374e-04  4.761778e-04  4.703426e-04
## [241]  4.638548e-04  4.620689e-04  4.528993e-04  4.482687e-04  4.475278e-04
## [246]  4.432608e-04  4.393605e-04  4.368357e-04  4.246050e-04  4.229343e-04
## [251]  4.196815e-04  4.182655e-04  4.127157e-04  4.045682e-04  3.989786e-04
## [256]  3.976214e-04  3.917360e-04  3.881210e-04  3.826480e-04  3.759254e-04
## [261]  3.738818e-04  3.710175e-04  3.669762e-04  3.622481e-04  3.585873e-04
## [266]  3.558243e-04  3.491785e-04  3.458637e-04  3.439279e-04  3.393230e-04
## [271]  3.376086e-04  3.307778e-04  3.273143e-04  3.249111e-04  3.234981e-04
## [276]  3.174199e-04  3.127753e-04  3.073321e-04  3.044674e-04  3.025067e-04
## [281]  2.951065e-04  2.944784e-04  2.919351e-04  2.892315e-04  2.832859e-04
## [286]  2.822379e-04  2.779857e-04  2.753967e-04  2.717638e-04  2.678291e-04
## [291]  2.672292e-04  2.611973e-04  2.565088e-04  2.558961e-04  2.506086e-04
## [296]  2.482989e-04  2.414296e-04  2.397899e-04  2.365502e-04  2.352290e-04
## [301]  2.323899e-04  2.280537e-04  2.213028e-04  2.188037e-04  2.142649e-04
## [306]  2.100792e-04  2.067320e-04  2.053777e-04  2.026671e-04  2.018230e-04
## [311]  1.980526e-04  1.904292e-04  1.894716e-04  1.864499e-04  1.850811e-04
## [316]  1.834166e-04  1.796908e-04  1.744401e-04  1.729305e-04  1.684677e-04
## [321]  1.660478e-04  1.636391e-04  1.595591e-04  1.562616e-04  1.529729e-04
## [326]  1.517654e-04  1.488815e-04  1.463277e-04  1.433533e-04  1.423014e-04
## [331]  1.390198e-04  1.359203e-04  1.348303e-04  1.299133e-04  1.281431e-04
## [336]  1.276462e-04  1.213506e-04  1.187774e-04  1.131342e-04  1.114007e-04
## [341]  1.094324e-04  1.091030e-04  1.073766e-04  1.050688e-04  1.031345e-04
## [346]  9.707818e-05  9.438206e-05  9.345906e-05  9.193936e-05  8.864049e-05
## [351]  8.432943e-05  8.285332e-05  7.953285e-05  7.874769e-05  7.639815e-05
## [356]  7.302528e-05  7.190236e-05  7.126995e-05  7.040145e-05  6.784235e-05
## [361]  6.518675e-05  6.345800e-05  6.038793e-05  5.941359e-05  5.445495e-05
## [366]  5.202175e-05  5.030840e-05  4.815442e-05  4.794592e-05  4.516684e-05
## [371]  4.057110e-05  3.668717e-05  3.564962e-05  3.524979e-05  3.367417e-05
## [376]  3.066612e-05  2.907986e-05  2.655688e-05  2.372950e-05  2.284795e-05
## [381]  1.961544e-05  1.749091e-05  1.492784e-05  1.186211e-05  1.019587e-05
## [386]  9.477710e-06  7.626018e-06  6.570130e-06  5.932971e-06  1.620571e-06
## [391]  1.338307e-06 -1.870985e-17 -1.349702e-06 -2.883140e-06 -4.203080e-06
## [396] -7.717086e-06 -9.861596e-06 -1.198816e-05 -1.321449e-05 -1.498917e-05
## [401] -1.659298e-05 -1.920996e-05 -2.111557e-05 -2.412200e-05 -2.437407e-05
## [406] -2.551218e-05 -2.647626e-05 -2.789977e-05 -2.931594e-05 -3.373566e-05
## [411] -3.486207e-05 -3.823380e-05 -3.866737e-05 -4.067269e-05 -4.268700e-05
## [416] -4.294409e-05 -4.576562e-05 -4.686890e-05 -4.942692e-05 -5.133282e-05
## [421] -5.314809e-05 -5.394057e-05 -5.620284e-05 -5.711008e-05 -5.976065e-05
## [426] -6.131710e-05 -6.215567e-05 -6.311298e-05 -6.483212e-05 -6.750721e-05
## [431] -6.918466e-05 -7.195877e-05 -7.199284e-05 -7.432005e-05 -7.478917e-05
## [436] -7.638996e-05 -7.963144e-05 -8.193325e-05 -8.270950e-05 -8.372708e-05
## [441] -8.506837e-05 -8.649832e-05 -8.722639e-05 -9.038460e-05 -9.074864e-05
## [446] -9.260406e-05 -9.388328e-05 -9.512934e-05 -9.627572e-05 -9.853415e-05
## [451] -9.959154e-05 -1.010476e-04 -1.024710e-04 -1.040793e-04 -1.049315e-04
## [456] -1.073156e-04 -1.092401e-04 -1.107808e-04 -1.112678e-04 -1.136043e-04
## [461] -1.147101e-04 -1.166354e-04 -1.174895e-04 -1.181992e-04 -1.207153e-04
## [466] -1.209009e-04 -1.226239e-04 -1.237143e-04 -1.260680e-04 -1.273862e-04
## [471] -1.279492e-04 -1.303486e-04 -1.305193e-04 -1.323121e-04 -1.331228e-04
## [476] -1.343140e-04 -1.353673e-04 -1.380034e-04 -1.390179e-04 -1.407401e-04
## [481] -1.432556e-04 -1.441151e-04 -1.445929e-04 -1.462765e-04 -1.464146e-04
## [486] -1.492066e-04 -1.509739e-04 -1.522748e-04 -1.534072e-04 -1.548708e-04
## [491] -1.551870e-04 -1.560921e-04 -1.579042e-04 -1.591345e-04 -1.598855e-04
## [496] -1.623456e-04 -1.629268e-04 -1.632124e-04 -1.649770e-04 -1.681378e-04
## [501] -1.696025e-04 -1.702991e-04 -1.707788e-04 -1.727456e-04 -1.744291e-04
## [506] -1.756015e-04 -1.761279e-04 -1.774330e-04 -1.786463e-04 -1.790221e-04
## [511] -1.810208e-04 -1.814839e-04 -1.838277e-04 -1.854665e-04 -1.860751e-04
## [516] -1.865867e-04 -1.881895e-04 -1.884773e-04 -1.906462e-04 -1.923582e-04
## [521] -1.937866e-04 -1.953820e-04 -1.958180e-04 -1.961516e-04 -1.974538e-04
## [526] -1.988818e-04 -2.002671e-04 -2.024507e-04 -2.032488e-04 -2.035208e-04
## [531] -2.041066e-04 -2.044326e-04 -2.056014e-04 -2.070359e-04 -2.089285e-04
## [536] -2.092077e-04 -2.097278e-04 -2.107682e-04 -2.114311e-04 -2.132221e-04
## [541] -2.148662e-04 -2.154612e-04 -2.160521e-04 -2.183079e-04 -2.187966e-04
## [546] -2.200508e-04 -2.214073e-04 -2.215447e-04 -2.225054e-04 -2.236905e-04
## [551] -2.252541e-04 -2.268685e-04 -2.272575e-04 -2.281633e-04 -2.292899e-04
## [556] -2.301409e-04 -2.318638e-04 -2.329982e-04 -2.346695e-04 -2.348047e-04
## [561] -2.355188e-04 -2.368533e-04 -2.376901e-04 -2.388599e-04 -2.399154e-04
## [566] -2.403380e-04 -2.417888e-04 -2.437302e-04 -2.447860e-04 -2.460921e-04
## [571] -2.472293e-04 -2.484145e-04 -2.491783e-04 -2.509339e-04 -2.515683e-04
## [576] -2.531452e-04 -2.539318e-04 -2.545698e-04 -2.553871e-04 -2.559578e-04
## [581] -2.576565e-04 -2.581009e-04 -2.586323e-04 -2.597197e-04 -2.609459e-04
## [586] -2.613960e-04 -2.620205e-04 -2.644654e-04 -2.656892e-04 -2.666524e-04
## [591] -2.673337e-04 -2.681790e-04 -2.689225e-04 -2.698562e-04 -2.715129e-04
## [596] -2.720379e-04 -2.727594e-04 -2.745122e-04 -2.752390e-04 -2.755810e-04
## [601] -2.768072e-04 -2.780858e-04 -2.790473e-04 -2.801317e-04 -2.803586e-04
## [606] -2.820192e-04 -2.832625e-04 -2.854305e-04 -2.857144e-04 -2.876815e-04
## [611] -2.878380e-04 -2.884538e-04 -2.891541e-04 -2.907250e-04 -2.917539e-04
## [616] -2.932195e-04 -2.943748e-04 -2.957441e-04 -2.973452e-04 -2.985603e-04
## [621] -2.994890e-04 -3.002264e-04 -3.005662e-04 -3.022601e-04 -3.044719e-04
## [626] -3.051538e-04 -3.059363e-04 -3.063682e-04 -3.074674e-04 -3.082755e-04
## [631] -3.083657e-04 -3.100345e-04 -3.107357e-04 -3.113755e-04 -3.128002e-04
## [636] -3.152364e-04 -3.159414e-04 -3.166804e-04 -3.176924e-04 -3.181594e-04
## [641] -3.189197e-04 -3.203625e-04 -3.207713e-04 -3.216369e-04 -3.230945e-04
## [646] -3.240258e-04 -3.248874e-04 -3.262363e-04 -3.275372e-04 -3.284015e-04
## [651] -3.297455e-04 -3.303071e-04 -3.309880e-04 -3.320454e-04 -3.329779e-04
## [656] -3.336239e-04 -3.362126e-04 -3.372244e-04 -3.378039e-04 -3.385448e-04
## [661] -3.409595e-04 -3.411858e-04 -3.418127e-04 -3.431766e-04 -3.434815e-04
## [666] -3.449635e-04 -3.463667e-04 -3.472854e-04 -3.485725e-04 -3.502785e-04
## [671] -3.509747e-04 -3.520566e-04 -3.531638e-04 -3.551601e-04 -3.560203e-04
## [676] -3.566418e-04 -3.570847e-04 -3.585310e-04 -3.602744e-04 -3.610967e-04
## [681] -3.616566e-04 -3.629638e-04 -3.636405e-04 -3.639353e-04 -3.651109e-04
## [686] -3.669613e-04 -3.690309e-04 -3.699639e-04 -3.703569e-04 -3.713535e-04
## [691] -3.726638e-04 -3.740567e-04 -3.754701e-04 -3.761194e-04 -3.767864e-04
## [696] -3.777213e-04 -3.799030e-04 -3.808267e-04 -3.819755e-04 -3.834857e-04
## [701] -3.837790e-04 -3.853880e-04 -3.869188e-04 -3.883399e-04 -3.889301e-04
## [706] -3.901344e-04 -3.912256e-04 -3.932254e-04 -3.936947e-04 -3.951814e-04
## [711] -3.958712e-04 -3.967776e-04 -3.978265e-04 -3.997660e-04 -4.007556e-04
## [716] -4.019238e-04 -4.034114e-04 -4.035403e-04 -4.050289e-04 -4.052541e-04
## [721] -4.080345e-04 -4.090834e-04 -4.094695e-04 -4.112698e-04 -4.125872e-04
## [726] -4.128478e-04 -4.152092e-04 -4.155626e-04 -4.167706e-04 -4.188249e-04
## [731] -4.204053e-04 -4.221612e-04 -4.236266e-04 -4.245767e-04 -4.263832e-04
## [736] -4.284551e-04 -4.297482e-04 -4.303285e-04 -4.317808e-04 -4.335885e-04
## [741] -4.344217e-04 -4.347616e-04 -4.364964e-04 -4.373818e-04 -4.391172e-04
## [746] -4.417590e-04 -4.426768e-04 -4.430735e-04 -4.453556e-04 -4.473394e-04
## [751] -4.485087e-04 -4.501493e-04 -4.523150e-04 -4.533902e-04 -4.543564e-04
## [756] -4.557795e-04 -4.581434e-04 -4.598238e-04 -4.612678e-04 -4.626799e-04
## [761] -4.631666e-04 -4.660877e-04 -4.675214e-04 -4.688232e-04 -4.705382e-04
## [766] -4.714715e-04 -4.726896e-04 -4.763119e-04 -4.768514e-04 -4.786020e-04
## [771] -4.799153e-04 -4.815614e-04 -4.850054e-04 -4.855409e-04 -4.881833e-04
## [776] -4.902842e-04 -4.914433e-04 -4.925805e-04 -4.956809e-04 -4.970936e-04
## [781] -4.999324e-04 -5.013989e-04 -5.034043e-04 -5.052258e-04 -5.068240e-04
## [786] -5.097517e-04 -5.117376e-04 -5.139094e-04 -5.152766e-04 -5.167250e-04
## [791] -5.218357e-04 -5.230191e-04 -5.246908e-04 -5.272537e-04 -5.275848e-04
## [796] -5.295720e-04 -5.322458e-04 -5.370438e-04 -5.410951e-04 -5.423297e-04
## [801] -5.433727e-04 -5.453020e-04 -5.463111e-04 -5.540516e-04 -5.583612e-04
## [806] -5.641356e-04 -5.649842e-04 -5.691719e-04 -5.696339e-04 -5.728347e-04
## [811] -5.776630e-04 -5.794638e-04 -5.803156e-04 -5.841033e-04 -5.900049e-04
## [816] -5.951381e-04 -5.975822e-04 -6.050135e-04 -6.089236e-04 -6.105383e-04
## [821] -6.156085e-04 -6.217391e-04 -6.233087e-04 -6.304951e-04 -6.345962e-04
## [826] -6.480228e-04 -6.499241e-04 -6.563191e-04 -6.636438e-04 -6.666413e-04
## [831] -6.714717e-04 -6.816697e-04 -6.822580e-04 -7.032081e-04 -7.134800e-04
## [836] -7.253936e-04 -7.299377e-04 -7.378999e-04 -7.480423e-04 -7.599188e-04
## [841] -7.851336e-04 -7.904235e-04 -8.224269e-04 -8.353448e-04 -8.391237e-04
## [846] -8.502769e-04 -8.840958e-04 -9.142714e-04 -9.204617e-04 -9.839130e-04
## [851] -1.040658e-03 -1.134349e-03 -1.435179e-03 -2.275339e-03
evaluate_consistency_metrics(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
## $trustworthiness
## [1] 0.631316
## 
## $continuity
## [1] 0.8606687
## 
## $mantel_statistic
## [1] 0.3142657
## 
## $mantel_p
## [1] 0.001
cjtt_u_test(dist_bray_filt, BMI_filt, var_method = "analytic")
## $U_statistic
## [1] 0.06159278
## 
## $variance
## [1] 0.0005198166
## 
## $z_score
## [1] 2.701498
## 
## $p_value
## [1] 0.00690278
## 
## $method
## [1] "analytic"
gco_decomposition(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
##     consistency_score outlier        class
## 1                 0.0   FALSE       C-type
## 2                 0.0   FALSE       C-type
## 3                 0.0   FALSE       C-type
## 4                 0.0   FALSE       C-type
## 5                 0.2    TRUE       O-type
## 6                 0.1   FALSE       C-type
## 7                 0.0   FALSE       C-type
## 8                 0.0   FALSE       C-type
## 9                 0.0   FALSE       C-type
## 10                0.0   FALSE       C-type
## 11                0.0   FALSE       C-type
## 12                0.0   FALSE       C-type
## 13                0.1   FALSE       C-type
## 14                0.0   FALSE       C-type
## 15                0.0   FALSE       C-type
## 16                0.0   FALSE       C-type
## 17                0.0   FALSE       C-type
## 18                0.0   FALSE       C-type
## 19                0.0   FALSE       C-type
## 20                0.0   FALSE       C-type
## 21                0.0   FALSE       C-type
## 22                0.0   FALSE       C-type
## 23                0.0   FALSE       C-type
## 24                0.6    TRUE       O-type
## 25                0.1   FALSE       C-type
## 26                0.0   FALSE       C-type
## 27                0.3    TRUE       O-type
## 28                0.0   FALSE       C-type
## 29                0.0   FALSE       C-type
## 30                0.1   FALSE       C-type
## 31                0.1   FALSE       C-type
## 32                0.1   FALSE       C-type
## 33                0.1   FALSE       C-type
## 34                0.0   FALSE       C-type
## 35                0.0   FALSE       C-type
## 36                0.0   FALSE       C-type
## 37                0.1   FALSE       C-type
## 38                0.1   FALSE       C-type
## 39                0.0   FALSE       C-type
## 40                0.0   FALSE       C-type
## 41                0.0   FALSE       C-type
## 42                0.2   FALSE Intermediate
## 43                0.0   FALSE       C-type
## 44                0.1   FALSE       C-type
## 45                0.0   FALSE       C-type
## 46                0.0   FALSE       C-type
## 47                0.1   FALSE       C-type
## 48                0.0   FALSE       C-type
## 49                0.0   FALSE       C-type
## 50                0.0   FALSE       C-type
## 51                0.1   FALSE       C-type
## 52                0.0   FALSE       C-type
## 53                0.1   FALSE       C-type
## 54                0.0   FALSE       C-type
## 55                0.0   FALSE       C-type
## 56                0.0   FALSE       C-type
## 57                0.1   FALSE       C-type
## 58                0.0   FALSE       C-type
## 59                0.2   FALSE Intermediate
## 60                0.0   FALSE       C-type
## 61                0.0   FALSE       C-type
## 62                0.3   FALSE Intermediate
## 63                0.0   FALSE       C-type
## 64                0.1   FALSE       C-type
## 65                0.0   FALSE       C-type
## 66                0.1   FALSE       C-type
## 67                0.1   FALSE       C-type
## 68                0.1   FALSE       C-type
## 69                0.0   FALSE       C-type
## 70                0.1   FALSE       C-type
## 71                0.0   FALSE       C-type
## 72                0.1   FALSE       C-type
## 73                0.0   FALSE       C-type
## 74                0.1   FALSE       C-type
## 75                0.0   FALSE       C-type
## 76                0.0   FALSE       C-type
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## 78                0.0   FALSE       C-type
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## 80                0.1    TRUE       O-type
## 81                0.0   FALSE       C-type
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## 84                0.2   FALSE Intermediate
## 85                0.0   FALSE       C-type
## 86                0.0   FALSE       C-type
## 87                0.0    TRUE       O-type
## 88                0.0   FALSE       C-type
## 89                0.0   FALSE       C-type
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## 102               0.0   FALSE       C-type
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## 105               0.2   FALSE Intermediate
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## 107               0.0   FALSE       C-type
## 108               0.2   FALSE Intermediate
## 109               0.0   FALSE       C-type
## 110               0.1   FALSE       C-type
## 111               0.2   FALSE Intermediate
## 112               0.0   FALSE       C-type
## 113               0.1   FALSE       C-type
## 114               0.1   FALSE       C-type
## 115               0.0   FALSE       C-type
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## 127               0.1   FALSE       C-type
## 128               0.0   FALSE       C-type
## 129               0.0   FALSE       C-type
## 130               0.2   FALSE Intermediate
## 131               0.1   FALSE       C-type
## 132               0.0    TRUE       O-type
## 133               0.0   FALSE       C-type
## 134               0.1   FALSE       C-type
## 135               0.3   FALSE Intermediate
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## 137               0.0   FALSE       C-type
## 138               0.0   FALSE       C-type
## 139               0.0   FALSE       C-type
## 140               0.0   FALSE       C-type
## 141               0.1   FALSE       C-type
## 142               0.1   FALSE       C-type
## 143               0.2   FALSE Intermediate
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## 145               0.0   FALSE       C-type
## 146               0.1   FALSE       C-type
## 147               0.0   FALSE       C-type
## 148               0.0   FALSE       C-type
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## 151               0.0   FALSE       C-type
## 152               0.0   FALSE       C-type
## 153               0.0   FALSE       C-type
## 154               0.0   FALSE       C-type
## 155               0.0   FALSE       C-type
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## 159               0.1   FALSE       C-type
## 160               0.1   FALSE       C-type
## 161               0.1   FALSE       C-type
## 162               0.2   FALSE Intermediate
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## 164               0.0   FALSE       C-type
## 165               0.1   FALSE       C-type
## 166               0.1   FALSE       C-type
## 167               0.0   FALSE       C-type
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## 171               0.1   FALSE       C-type
## 172               0.0   FALSE       C-type
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## 176               0.0   FALSE       C-type
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## 181               0.1   FALSE       C-type
## 182               0.0   FALSE       C-type
## 183               0.0   FALSE       C-type
## 184               0.2   FALSE Intermediate
## 185               0.2   FALSE Intermediate
## 186               0.0   FALSE       C-type
## 187               0.0   FALSE       C-type
## 188               0.2   FALSE Intermediate
## 189               0.1   FALSE       C-type
## 190               0.0   FALSE       C-type
## 191               0.8    TRUE       O-type
## 192               0.0   FALSE       C-type
## 193               0.2   FALSE Intermediate
## 194               0.0   FALSE       C-type
## 195               0.0   FALSE       C-type
## 196               0.1   FALSE       C-type
## 197               0.2   FALSE Intermediate
## 198               0.1   FALSE       C-type
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## 200               0.1   FALSE       C-type
## 201               0.0   FALSE       C-type
## 202               0.0   FALSE       C-type
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## 205               0.0   FALSE       C-type
## 206               0.1   FALSE       C-type
## 207               0.0   FALSE       C-type
## 208               0.2   FALSE Intermediate
## 209               0.0   FALSE       C-type
## 210               0.1   FALSE       C-type
## 211               0.2   FALSE Intermediate
## 212               0.4    TRUE       O-type
## 213               0.0   FALSE       C-type
## 214               0.0   FALSE       C-type
## 215               0.1   FALSE       C-type
## 216               0.1   FALSE       C-type
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## 220               0.0   FALSE       C-type
## 221               0.1   FALSE       C-type
## 222               0.1   FALSE       C-type
## 223               0.2   FALSE Intermediate
## 224               0.0    TRUE       O-type
## 225               0.0   FALSE       C-type
## 226               0.0    TRUE       O-type
## 227               0.0   FALSE       C-type
## 228               0.1   FALSE       C-type
## 229               0.0   FALSE       C-type
## 230               0.1   FALSE       C-type
## 231               0.0   FALSE       C-type
## 232               0.1   FALSE       C-type
## 233               0.0   FALSE       C-type
## 234               0.1   FALSE       C-type
## 235               0.0   FALSE       C-type
## 236               0.1   FALSE       C-type
## 237               0.1   FALSE       C-type
## 238               0.1   FALSE       C-type
## 239               0.1   FALSE       C-type
## 240               0.1   FALSE       C-type
## 241               0.0   FALSE       C-type
## 242               0.0   FALSE       C-type
## 243               0.1   FALSE       C-type
## 244               0.0   FALSE       C-type
## 245               0.3    TRUE       O-type
## 246               0.0   FALSE       C-type
## 247               0.3   FALSE Intermediate
## 248               0.0   FALSE       C-type
## 249               0.0   FALSE       C-type
## 250               0.0   FALSE       C-type
## 251               0.1   FALSE       C-type
## 252               0.0   FALSE       C-type
## 253               0.0   FALSE       C-type
## 254               0.0   FALSE       C-type
## 255               0.2   FALSE Intermediate
## 256               0.2   FALSE Intermediate
## 257               0.0   FALSE       C-type
## 258               0.1   FALSE       C-type
## 259               0.1   FALSE       C-type
## 260               0.0   FALSE       C-type
## 261               0.1   FALSE       C-type
## 262               0.0   FALSE       C-type
## 263               0.0   FALSE       C-type
## 264               0.2   FALSE Intermediate
## 265               0.1   FALSE       C-type
## 266               0.1   FALSE       C-type
## 267               0.0   FALSE       C-type
## 268               0.2   FALSE Intermediate
## 269               0.1   FALSE       C-type
## 270               0.2   FALSE Intermediate
## 271               0.0   FALSE       C-type
## 272               0.0   FALSE       C-type
## 273               0.0   FALSE       C-type
## 274               0.0   FALSE       C-type
## 275               0.0    TRUE       O-type
## 276               0.1   FALSE       C-type
## 277               0.2   FALSE Intermediate
## 278               0.1   FALSE       C-type
## 279               0.0   FALSE       C-type
## 280               0.1    TRUE       O-type
## 281               0.1   FALSE       C-type
## 282               0.1   FALSE       C-type
## 283               0.0   FALSE       C-type
## 284               0.1   FALSE       C-type
## 285               0.0   FALSE       C-type
## 286               0.0   FALSE       C-type
## 287               0.1   FALSE       C-type
## 288               0.0   FALSE       C-type
## 289               0.0   FALSE       C-type
## 290               0.1   FALSE       C-type
## 291               0.0   FALSE       C-type
## 292               0.0   FALSE       C-type
## 293               0.2   FALSE Intermediate
## 294               0.0   FALSE       C-type
## 295               0.0   FALSE       C-type
## 296               0.0   FALSE       C-type
## 297               0.0   FALSE       C-type
## 298               0.0   FALSE       C-type
## 299               0.0   FALSE       C-type
## 300               0.0   FALSE       C-type
## 301               0.0   FALSE       C-type
## 302               0.0   FALSE       C-type
## 303               0.0   FALSE       C-type
## 304               0.1   FALSE       C-type
## 305               0.1   FALSE       C-type
## 306               0.1   FALSE       C-type
## 307               0.0   FALSE       C-type
## 308               0.1   FALSE       C-type
## 309               0.2   FALSE Intermediate
## 310               0.0   FALSE       C-type
## 311               0.1   FALSE       C-type
## 312               0.0   FALSE       C-type
## 313               0.0   FALSE       C-type
## 314               0.1   FALSE       C-type
## 315               0.0   FALSE       C-type
## 316               0.1   FALSE       C-type
## 317               0.0   FALSE       C-type
## 318               0.0   FALSE       C-type
## 319               0.1   FALSE       C-type
## 320               0.0   FALSE       C-type
## 321               0.0   FALSE       C-type
## 322               0.0   FALSE       C-type
## 323               0.1   FALSE       C-type
## 324               0.0   FALSE       C-type
## 325               0.2   FALSE Intermediate
## 326               0.0   FALSE       C-type
## 327               0.1   FALSE       C-type
## 328               0.3   FALSE Intermediate
## 329               0.0   FALSE       C-type
## 330               0.1   FALSE       C-type
## 331               0.0   FALSE       C-type
## 332               0.3   FALSE Intermediate
## 333               0.1   FALSE       C-type
## 334               0.0   FALSE       C-type
## 335               0.1   FALSE       C-type
## 336               0.0   FALSE       C-type
## 337               0.2   FALSE Intermediate
## 338               0.1   FALSE       C-type
## 339               0.0   FALSE       C-type
## 340               0.0   FALSE       C-type
## 341               0.1   FALSE       C-type
## 342               0.1   FALSE       C-type
## 343               0.0   FALSE       C-type
## 344               0.0   FALSE       C-type
## 345               0.0   FALSE       C-type
## 346               0.0   FALSE       C-type
## 347               0.3   FALSE Intermediate
## 348               0.0   FALSE       C-type
## 349               0.0   FALSE       C-type
## 350               0.1    TRUE       O-type
## 351               0.1   FALSE       C-type
## 352               0.0   FALSE       C-type
## 353               0.0   FALSE       C-type
## 354               0.1   FALSE       C-type
## 355               0.0   FALSE       C-type
## 356               0.2   FALSE Intermediate
## 357               0.0   FALSE       C-type
## 358               0.0   FALSE       C-type
## 359               0.0   FALSE       C-type
## 360               0.0   FALSE       C-type
## 361               0.0    TRUE       O-type
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## 363               0.1   FALSE       C-type
## 364               0.1   FALSE       C-type
## 365               0.0   FALSE       C-type
## 366               0.0   FALSE       C-type
## 367               0.1   FALSE       C-type
## 368               0.2   FALSE Intermediate
## 369               0.1   FALSE       C-type
## 370               0.0   FALSE       C-type
## 371               0.0   FALSE       C-type
## 372               0.0   FALSE       C-type
## 373               0.3   FALSE Intermediate
## 374               0.0   FALSE       C-type
## 375               0.1   FALSE       C-type
## 376               0.0   FALSE       C-type
## 377               0.1   FALSE       C-type
## 378               0.0   FALSE       C-type
## 379               0.0   FALSE       C-type
## 380               0.1   FALSE       C-type
## 381               0.1   FALSE       C-type
## 382               0.3    TRUE       O-type
## 383               0.0   FALSE       C-type
## 384               0.1   FALSE       C-type
## 385               0.0   FALSE       C-type
## 386               0.0    TRUE       O-type
## 387               0.1   FALSE       C-type
## 388               0.0    TRUE       O-type
## 389               0.1   FALSE       C-type
## 390               0.1   FALSE       C-type
## 391               0.1   FALSE       C-type
## 392               0.0   FALSE       C-type
## 393               0.0   FALSE       C-type
## 394               0.0   FALSE       C-type
## 395               0.0   FALSE       C-type
## 396               0.1   FALSE       C-type
## 397               0.0   FALSE       C-type
## 398               0.1   FALSE       C-type
## 399               0.1   FALSE       C-type
## 400               0.0   FALSE       C-type
## 401               0.1   FALSE       C-type
## 402               0.1   FALSE       C-type
## 403               0.0   FALSE       C-type
## 404               0.0   FALSE       C-type
## 405               0.1   FALSE       C-type
## 406               0.1   FALSE       C-type
## 407               0.0   FALSE       C-type
## 408               0.0   FALSE       C-type
## 409               0.0   FALSE       C-type
## 410               0.1   FALSE       C-type
## 411               0.6    TRUE       O-type
## 412               0.1   FALSE       C-type
## 413               0.0   FALSE       C-type
## 414               0.0   FALSE       C-type
## 415               0.1   FALSE       C-type
## 416               0.0   FALSE       C-type
## 417               0.1   FALSE       C-type
## 418               0.0   FALSE       C-type
## 419               0.0   FALSE       C-type
## 420               0.0   FALSE       C-type
## 421               0.1   FALSE       C-type
## 422               0.0   FALSE       C-type
## 423               0.0   FALSE       C-type
## 424               0.1   FALSE       C-type
## 425               0.0   FALSE       C-type
## 426               0.6    TRUE       O-type
## 427               0.0   FALSE       C-type
## 428               0.0   FALSE       C-type
## 429               0.2   FALSE Intermediate
## 430               0.2   FALSE Intermediate
## 431               0.0   FALSE       C-type
## 432               0.1   FALSE       C-type
## 433               0.2   FALSE Intermediate
## 434               0.0   FALSE       C-type
## 435               0.1   FALSE       C-type
## 436               0.0   FALSE       C-type
## 437               0.0   FALSE       C-type
## 438               0.0   FALSE       C-type
## 439               0.1   FALSE       C-type
## 440               0.0   FALSE       C-type
## 441               0.2   FALSE Intermediate
## 442               0.0   FALSE       C-type
## 443               0.0   FALSE       C-type
## 444               0.0   FALSE       C-type
## 445               0.0   FALSE       C-type
## 446               0.0    TRUE       O-type
## 447               0.1   FALSE       C-type
## 448               0.1   FALSE       C-type
## 449               0.1   FALSE       C-type
## 450               0.0   FALSE       C-type
## 451               0.2   FALSE Intermediate
## 452               0.1   FALSE       C-type
## 453               0.1   FALSE       C-type
## 454               0.2   FALSE Intermediate
## 455               0.0   FALSE       C-type
## 456               0.1   FALSE       C-type
## 457               0.3   FALSE Intermediate
## 458               0.0   FALSE       C-type
## 459               0.0   FALSE       C-type
## 460               0.0   FALSE       C-type
## 461               0.0   FALSE       C-type
## 462               0.7    TRUE       O-type
## 463               0.0   FALSE       C-type
## 464               0.2   FALSE Intermediate
## 465               0.1   FALSE       C-type
## 466               0.1   FALSE       C-type
## 467               0.2    TRUE       O-type
## 468               0.0   FALSE       C-type
## 469               0.0    TRUE       O-type
## 470               0.1   FALSE       C-type
## 471               0.1   FALSE       C-type
## 472               0.1   FALSE       C-type
## 473               0.4   FALSE Intermediate
## 474               0.3    TRUE       O-type
## 475               0.0    TRUE       O-type
## 476               0.0   FALSE       C-type
## 477               0.0   FALSE       C-type
## 478               0.0   FALSE       C-type
## 479               0.1   FALSE       C-type
## 480               0.0    TRUE       O-type
## 481               0.0   FALSE       C-type
## 482               0.1   FALSE       C-type
## 483               0.0   FALSE       C-type
## 484               0.0   FALSE       C-type
## 485               0.1   FALSE       C-type
## 486               0.1   FALSE       C-type
## 487               0.0   FALSE       C-type
## 488               0.4    TRUE       O-type
## 489               0.5    TRUE       O-type
## 490               0.0   FALSE       C-type
## 491               0.0   FALSE       C-type
## 492               0.2   FALSE Intermediate
## 493               0.1   FALSE       C-type
## 494               0.0   FALSE       C-type
## 495               0.1   FALSE       C-type
## 496               0.1   FALSE       C-type
## 497               0.0    TRUE       O-type
## 498               0.2   FALSE Intermediate
## 499               0.0   FALSE       C-type
## 500               0.2   FALSE Intermediate
## 501               0.1    TRUE       O-type
## 502               0.0    TRUE       O-type
## 503               0.2    TRUE       O-type
## 504               0.1   FALSE       C-type
## 505               0.0   FALSE       C-type
## 506               0.0   FALSE       C-type
## 507               0.4   FALSE Intermediate
## 508               0.5    TRUE       O-type
## 509               0.0   FALSE       C-type
## 510               0.0   FALSE       C-type
## 511               0.0    TRUE       O-type
## 512               0.0   FALSE       C-type
## 513               0.0   FALSE       C-type
## 514               0.3   FALSE Intermediate
## 515               0.0   FALSE       C-type
## 516               0.0   FALSE       C-type
## 517               0.3    TRUE       O-type
## 518               0.1   FALSE       C-type
## 519               0.1   FALSE       C-type
## 520               0.1   FALSE       C-type
## 521               0.1   FALSE       C-type
## 522               0.0   FALSE       C-type
## 523               0.3    TRUE       O-type
## 524               0.1   FALSE       C-type
## 525               0.0    TRUE       O-type
## 526               0.0   FALSE       C-type
## 527               0.1   FALSE       C-type
## 528               0.2    TRUE       O-type
## 529               0.0   FALSE       C-type
## 530               0.0   FALSE       C-type
## 531               0.2   FALSE Intermediate
## 532               0.0   FALSE       C-type
## 533               0.0   FALSE       C-type
## 534               0.0   FALSE       C-type
## 535               0.0    TRUE       O-type
## 536               0.2   FALSE Intermediate
## 537               0.1   FALSE       C-type
## 538               0.0    TRUE       O-type
## 539               0.1   FALSE       C-type
## 540               0.0   FALSE       C-type
## 541               0.0   FALSE       C-type
## 542               0.1   FALSE       C-type
## 543               0.1   FALSE       C-type
## 544               0.0   FALSE       C-type
## 545               0.1   FALSE       C-type
## 546               0.1   FALSE       C-type
## 547               0.0   FALSE       C-type
## 548               0.1   FALSE       C-type
## 549               0.2   FALSE Intermediate
## 550               0.0   FALSE       C-type
## 551               0.0    TRUE       O-type
## 552               0.1   FALSE       C-type
## 553               0.0   FALSE       C-type
## 554               0.0    TRUE       O-type
## 555               0.1   FALSE       C-type
## 556               0.2    TRUE       O-type
## 557               0.0   FALSE       C-type
## 558               0.4    TRUE       O-type
## 559               0.0   FALSE       C-type
## 560               0.0   FALSE       C-type
## 561               0.0   FALSE       C-type
## 562               0.0   FALSE       C-type
## 563               0.1   FALSE       C-type
## 564               0.0   FALSE       C-type
## 565               0.1   FALSE       C-type
## 566               0.0   FALSE       C-type
## 567               0.0   FALSE       C-type
## 568               0.1   FALSE       C-type
## 569               0.0   FALSE       C-type
## 570               0.2   FALSE Intermediate
## 571               0.0   FALSE       C-type
## 572               0.1    TRUE       O-type
## 573               0.1   FALSE       C-type
## 574               0.1   FALSE       C-type
## 575               0.1   FALSE       C-type
## 576               0.3   FALSE Intermediate
## 577               0.0   FALSE       C-type
## 578               0.0   FALSE       C-type
## 579               0.0   FALSE       C-type
## 580               0.0   FALSE       C-type
## 581               0.1   FALSE       C-type
## 582               0.1   FALSE       C-type
## 583               0.2   FALSE Intermediate
## 584               0.1   FALSE       C-type
## 585               0.0    TRUE       O-type
## 586               0.0    TRUE       O-type
## 587               0.1   FALSE       C-type
## 588               0.0    TRUE       O-type
## 589               0.0   FALSE       C-type
## 590               0.0   FALSE       C-type
## 591               0.0    TRUE       O-type
## 592               0.2    TRUE       O-type
## 593               0.1   FALSE       C-type
## 594               0.1   FALSE       C-type
## 595               0.1   FALSE       C-type
## 596               0.2   FALSE Intermediate
## 597               0.0   FALSE       C-type
## 598               0.0   FALSE       C-type
## 599               0.0   FALSE       C-type
## 600               0.1   FALSE       C-type
## 601               0.1    TRUE       O-type
## 602               0.1   FALSE       C-type
## 603               0.0   FALSE       C-type
## 604               0.2   FALSE Intermediate
## 605               0.2   FALSE Intermediate
## 606               0.0   FALSE       C-type
## 607               0.1   FALSE       C-type
## 608               0.0    TRUE       O-type
## 609               0.0   FALSE       C-type
## 610               0.0   FALSE       C-type
## 611               0.0    TRUE       O-type
## 612               0.0   FALSE       C-type
## 613               0.0   FALSE       C-type
## 614               0.0   FALSE       C-type
## 615               0.0   FALSE       C-type
## 616               0.1   FALSE       C-type
## 617               0.1   FALSE       C-type
## 618               0.1   FALSE       C-type
## 619               0.0   FALSE       C-type
## 620               0.0   FALSE       C-type
## 621               0.1   FALSE       C-type
## 622               0.0   FALSE       C-type
## 623               0.0   FALSE       C-type
## 624               0.0   FALSE       C-type
## 625               0.0   FALSE       C-type
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## 627               0.0   FALSE       C-type
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## 629               0.0   FALSE       C-type
## 630               0.0   FALSE       C-type
## 631               0.1   FALSE       C-type
## 632               0.2    TRUE       O-type
## 633               0.0   FALSE       C-type
## 634               0.0   FALSE       C-type
## 635               0.0   FALSE       C-type
## 636               0.2   FALSE Intermediate
## 637               0.0   FALSE       C-type
## 638               0.1   FALSE       C-type
## 639               0.0   FALSE       C-type
## 640               0.0   FALSE       C-type
## 641               0.1   FALSE       C-type
## 642               0.1    TRUE       O-type
## 643               0.1   FALSE       C-type
## 644               0.3   FALSE Intermediate
## 645               0.2    TRUE       O-type
## 646               0.0   FALSE       C-type
## 647               0.0   FALSE       C-type
## 648               0.0   FALSE       C-type
## 649               0.2    TRUE       O-type
## 650               0.2   FALSE Intermediate
## 651               0.0   FALSE       C-type
## 652               0.0   FALSE       C-type
## 653               0.0   FALSE       C-type
## 654               0.0   FALSE       C-type
## 655               0.1   FALSE       C-type
## 656               0.1   FALSE       C-type
## 657               0.0    TRUE       O-type
## 658               0.2   FALSE Intermediate
## 659               0.0   FALSE       C-type
## 660               0.0   FALSE       C-type
## 661               0.2   FALSE Intermediate
## 662               0.0   FALSE       C-type
## 663               0.0   FALSE       C-type
## 664               0.0   FALSE       C-type
## 665               0.0   FALSE       C-type
## 666               0.3   FALSE Intermediate
## 667               0.0   FALSE       C-type
## 668               0.1   FALSE       C-type
## 669               0.0   FALSE       C-type
## 670               0.0   FALSE       C-type
## 671               0.0   FALSE       C-type
## 672               0.1   FALSE       C-type
## 673               0.2   FALSE Intermediate
## 674               0.1   FALSE       C-type
## 675               0.0   FALSE       C-type
## 676               0.1   FALSE       C-type
## 677               0.0   FALSE       C-type
## 678               0.2   FALSE Intermediate
## 679               0.0   FALSE       C-type
## 680               0.2   FALSE Intermediate
## 681               0.0    TRUE       O-type
## 682               0.2   FALSE Intermediate
## 683               0.0   FALSE       C-type
## 684               0.1   FALSE       C-type
## 685               0.0   FALSE       C-type
## 686               0.1   FALSE       C-type
## 687               0.0   FALSE       C-type
## 688               0.1   FALSE       C-type
## 689               0.1   FALSE       C-type
## 690               0.1   FALSE       C-type
## 691               0.0   FALSE       C-type
## 692               0.1   FALSE       C-type
## 693               0.0   FALSE       C-type
## 694               0.0   FALSE       C-type
## 695               0.0   FALSE       C-type
## 696               0.0   FALSE       C-type
## 697               0.0   FALSE       C-type
## 698               0.0   FALSE       C-type
## 699               0.0   FALSE       C-type
## 700               0.1   FALSE       C-type
## 701               0.0   FALSE       C-type
## 702               0.1   FALSE       C-type
## 703               0.0   FALSE       C-type
## 704               0.0   FALSE       C-type
## 705               0.0   FALSE       C-type
## 706               0.0    TRUE       O-type
## 707               0.0   FALSE       C-type
## 708               0.1   FALSE       C-type
## 709               0.1   FALSE       C-type
## 710               0.1   FALSE       C-type
## 711               0.1   FALSE       C-type
## 712               0.1   FALSE       C-type
## 713               0.2    TRUE       O-type
## 714               0.0   FALSE       C-type
## 715               0.0   FALSE       C-type
## 716               0.0   FALSE       C-type
## 717               0.0   FALSE       C-type
## 718               0.2   FALSE Intermediate
## 719               0.2   FALSE Intermediate
## 720               0.1   FALSE       C-type
## 721               0.0   FALSE       C-type
## 722               0.1   FALSE       C-type
## 723               0.0   FALSE       C-type
## 724               0.0   FALSE       C-type
## 725               0.0   FALSE       C-type
## 726               0.0   FALSE       C-type
## 727               0.1   FALSE       C-type
## 728               0.0   FALSE       C-type
## 729               0.0   FALSE       C-type
## 730               0.0   FALSE       C-type
## 731               0.1   FALSE       C-type
## 732               0.0   FALSE       C-type
## 733               0.0   FALSE       C-type
## 734               0.0   FALSE       C-type
## 735               0.2   FALSE Intermediate
## 736               0.0    TRUE       O-type
## 737               0.0    TRUE       O-type
## 738               0.0   FALSE       C-type
## 739               0.1   FALSE       C-type
## 740               0.0   FALSE       C-type
## 741               0.3   FALSE Intermediate
## 742               0.1   FALSE       C-type
## 743               0.0   FALSE       C-type
## 744               0.1   FALSE       C-type
## 745               0.0   FALSE       C-type
## 746               0.0   FALSE       C-type
## 747               0.1   FALSE       C-type
## 748               0.1   FALSE       C-type
## 749               0.0   FALSE       C-type
## 750               0.1   FALSE       C-type
## 751               0.0   FALSE       C-type
## 752               0.0   FALSE       C-type
## 753               0.1   FALSE       C-type
## 754               0.1   FALSE       C-type
## 755               0.0   FALSE       C-type
## 756               0.0   FALSE       C-type
## 757               0.1   FALSE       C-type
## 758               0.0   FALSE       C-type
## 759               0.0   FALSE       C-type
## 760               0.0   FALSE       C-type
## 761               0.1   FALSE       C-type
## 762               0.3   FALSE Intermediate
## 763               0.0   FALSE       C-type
## 764               0.0   FALSE       C-type
## 765               0.0   FALSE       C-type
## 766               0.0   FALSE       C-type
## 767               0.0    TRUE       O-type
## 768               0.0   FALSE       C-type
## 769               0.1   FALSE       C-type
## 770               0.0   FALSE       C-type
## 771               0.0    TRUE       O-type
## 772               0.0   FALSE       C-type
## 773               0.0   FALSE       C-type
## 774               0.0   FALSE       C-type
## 775               0.1   FALSE       C-type
## 776               0.1   FALSE       C-type
## 777               0.1   FALSE       C-type
## 778               0.2   FALSE Intermediate
## 779               0.0   FALSE       C-type
## 780               0.1   FALSE       C-type
## 781               0.1    TRUE       O-type
## 782               0.0    TRUE       O-type
## 783               0.0   FALSE       C-type
## 784               0.1   FALSE       C-type
## 785               0.0   FALSE       C-type
## 786               0.0   FALSE       C-type
## 787               0.0   FALSE       C-type
## 788               0.1   FALSE       C-type
## 789               0.1   FALSE       C-type
## 790               0.0   FALSE       C-type
## 791               0.0   FALSE       C-type
## 792               0.1   FALSE       C-type
## 793               0.0   FALSE       C-type
## 794               0.1   FALSE       C-type
## 795               0.1    TRUE       O-type
## 796               0.1   FALSE       C-type
## 797               0.0   FALSE       C-type
## 798               0.1   FALSE       C-type
## 799               0.0   FALSE       C-type
## 800               0.0   FALSE       C-type
## 801               0.0   FALSE       C-type
## 802               0.0   FALSE       C-type
## 803               0.0    TRUE       O-type
## 804               0.0    TRUE       O-type
## 805               0.0   FALSE       C-type
## 806               0.1   FALSE       C-type
## 807               0.2   FALSE Intermediate
## 808               0.0   FALSE       C-type
## 809               0.0   FALSE       C-type
## 810               0.0   FALSE       C-type
## 811               0.1   FALSE       C-type
## 812               0.0   FALSE       C-type
## 813               0.3    TRUE       O-type
## 814               0.0   FALSE       C-type
## 815               0.0   FALSE       C-type
## 816               0.2    TRUE       O-type
## 817               0.0   FALSE       C-type
## 818               0.0   FALSE       C-type
## 819               0.2   FALSE Intermediate
## 820               0.2   FALSE Intermediate
## 821               0.0   FALSE       C-type
## 822               0.1   FALSE       C-type
## 823               0.0   FALSE       C-type
## 824               0.1    TRUE       O-type
## 825               0.3    TRUE       O-type
## 826               0.0   FALSE       C-type
## 827               0.0   FALSE       C-type
## 828               0.1   FALSE       C-type
## 829               0.1   FALSE       C-type
## 830               0.1   FALSE       C-type
## 831               0.0   FALSE       C-type
## 832               0.3    TRUE       O-type
## 833               0.1   FALSE       C-type
## 834               0.0   FALSE       C-type
## 835               0.1   FALSE       C-type
## 836               0.0   FALSE       C-type
## 837               0.1   FALSE       C-type
## 838               0.0   FALSE       C-type
## 839               0.0   FALSE       C-type
## 840               0.1   FALSE       C-type
## 841               0.1    TRUE       O-type
## 842               0.0   FALSE       C-type
## 843               0.0   FALSE       C-type
## 844               0.3    TRUE       O-type
## 845               0.0   FALSE       C-type
## 846               0.0   FALSE       C-type
## 847               0.3    TRUE       O-type
## 848               0.1   FALSE       C-type
## 849               0.1   FALSE       C-type
## 850               0.2   FALSE Intermediate
## 851               0.2   FALSE Intermediate
## 852               0.0   FALSE       C-type
## 853               0.5    TRUE       O-type
## 854               0.4    TRUE       O-type

HbA1c

HbA1c <- as.numeric(sample_data(ps)[["HbA1c...."]])
## Warning: NAs introduced by coercion
keep <- !is.na(HbA1c)   
ps_filt <- prune_samples(keep, ps)  
HbA1c_filt <- as.numeric(sample_data(ps_filt)[["HbA1c...."]])
dist_bray_filt <- phyloseq::distance(ps_filt, method = "bray")
res <- BetaTREND::gradient_projection(dist_bray_filt, HbA1c_filt)

res
## $projection_scores
##   [1] -0.3556041173 -0.0749918376 -0.3570747310 -0.1324896985  0.6422576114
##   [6] -0.3181374525 -0.1006192685 -0.3362409379 -0.2748079584 -0.0091455908
##  [11] -0.1958470132  0.1842838089 -0.0384888539  0.2265584567 -0.3305360748
##  [16] -0.1615183063  0.7228470552 -0.1581659419 -0.2387460669 -0.5164009994
##  [21] -0.1130332514  0.1839483900 -0.0504535139  0.8472711820  0.0980534352
##  [26] -0.0079161621  0.6473459476 -0.0262487574  0.1776292580  0.0914408941
##  [31] -0.3130903219 -0.2448742966  0.2795939525  0.0153993144 -0.0351210977
##  [36] -0.0173856320 -0.2073800083  0.4444660337 -0.5141069460  0.0933525128
##  [41] -0.0844087945 -0.1895587017 -0.0325766792  0.4438286733  0.1513394250
##  [46]  0.2001745086 -0.4750665394 -0.1403076087  0.2917164657 -0.2130225524
##  [51] -0.4107309770 -0.2178086827 -0.4220720097 -0.3410242319 -0.3464403873
##  [56]  0.1418008577 -0.3754292997 -0.1167142174 -0.1571212379 -0.1665435661
##  [61] -0.0378757947  0.0524710747 -0.4071151761  0.4440076818 -0.3113960028
##  [66] -0.1006069885 -0.2968398073 -0.2585010237 -0.3121681803 -0.1420506199
##  [71] -0.3024984222 -0.1161401463  0.0643584437 -0.3137955381 -0.3023334983
##  [76]  0.4025544988  0.0554307038 -0.1108074060  0.3945898539 -0.4717329425
##  [81] -0.2842759695 -0.1341236108 -0.3613584034 -0.2152909667  0.2738187139
##  [86] -0.2903609351  0.0363849487  0.0659314479 -0.2365719845 -0.4186352412
##  [91] -0.0800003610 -0.3804866903 -0.3471074844 -0.3121623822 -0.4560605321
##  [96] -0.0361365696 -0.0797064987 -0.2674808700 -0.3195353287 -0.1992905143
## [101] -0.0421085235 -0.3148101411 -0.2014490431 -0.1707974763 -0.1246829858
## [106] -0.1689285506  0.0359530834 -0.2612110787  0.0178448389 -0.2553461181
## [111] -0.0029994471 -0.0269754639 -0.2061625408  0.3069269689 -0.2427707624
## [116] -0.2865707958 -0.0990313179 -0.2569251264 -0.1057680564 -0.3116698573
## [121]  0.2769744053  0.1095680933  0.1286204721 -0.1667650168 -0.2109241263
## [126] -0.0128439815 -0.0517677663 -0.1003645742  0.4087359328 -0.4102021466
## [131] -0.1899482983  0.4116266364 -0.0787114119 -0.0364923172 -0.1101905257
## [136]  0.1056805795  0.3204775664  0.0659240379 -0.3379332882  0.4570544664
## [141] -0.3725297550  0.0110890357 -0.3031440909 -0.1703602232  0.1718223964
## [146] -0.2503396704  0.0817699981 -0.1004929285 -0.1625574792 -0.1015071147
## [151]  0.4023661727 -0.1595417526  0.1365391911 -0.3073335586 -0.2400303405
## [156] -0.2549541830 -0.2034413670  0.0755159120  0.4140364039 -0.0326866238
## [161]  0.4930151051  0.4025423197  0.0749033764  0.0298385811 -0.1942309891
## [166] -0.0798570843 -0.1511835076 -0.2575188311  0.5364933417 -0.3202916666
## [171] -0.2393210260 -0.2711775327  0.6580225520 -0.1181620827  0.0756115203
## [176] -0.2085702429 -0.3822264196  0.3159133218 -0.2002147551 -0.2689612214
## [181] -0.3637869845  0.0793648453 -0.1523705820 -0.0555014921  0.4945198157
## [186]  0.2960904123  0.3161471821  0.8368774067 -0.0023547060 -0.3527879652
## [191] -0.0973380719 -0.4151176748 -0.3997772864 -0.1623717238  0.0076983841
## [196] -0.0285372051  0.0629832623  0.0350414998 -0.3268455222 -0.1248999664
## [201]  0.0580482899  0.1697415144  0.0629844115 -0.0621977326  0.5605523469
## [206] -0.2486467650  0.2705184555  0.1807283564  0.7361967452 -0.3794932547
## [211] -0.1483032709 -0.0165280291 -0.0935611064  0.4342282003 -0.1829074149
## [216]  0.2896733362  0.0073584790 -0.2736662747 -0.0385648273 -0.3162586530
## [221]  0.0106534649  0.2206614347 -0.0120077162 -0.0238214502 -0.2601414546
## [226]  0.1649782051  0.1534469281 -0.3171088106 -0.2199535904 -0.1009023466
## [231] -0.2028191971 -0.1580003037 -0.0608731320 -0.2482970423 -0.3211957366
## [236] -0.1994301260 -0.1682552907  0.0485552981  0.0528011656 -0.3129309990
## [241]  0.5895965004 -0.3594189324  0.0001777118 -0.2249383180 -0.1416888094
## [246] -0.2460495770 -0.2602987163  0.4277390542 -0.1275422124 -0.3472403901
## [251] -0.2855520853 -0.1632171900 -0.1136906764 -0.2301929639 -0.0696595811
## [256] -0.4520664713 -0.0704832978  0.0120535317 -0.0367982459 -0.4719210146
## [261] -0.3545692886 -0.1201114233 -0.3699327112  0.1809569112 -0.1777688533
## [266]  0.0140099131  0.0597192782  0.0111346995  0.1173551638 -0.2567094633
## [271] -0.1576464286 -0.2408554924 -0.4378608149 -0.2805127398  0.0172876521
## [276] -0.3369339485 -0.2691051539 -0.0668112841 -0.0973294356 -0.1657846914
## [281]  0.2038438110 -0.0503748225 -0.1793152063  0.0033183975 -0.2833294895
## [286]  0.0809412082 -0.1409867086 -0.3520399466 -0.3500179410  0.2888055926
## [291] -0.0874791736 -0.5406709670 -0.0388858478 -0.0662689345 -0.0853477323
## [296] -0.0909817409 -0.1830367220 -0.2226143946 -0.4312097750 -0.2992858686
## [301] -0.2127995497 -0.4594971601 -0.1021065238  0.1001880982  0.3925654884
## [306]  0.0516000350 -0.1905028097 -0.2422004225 -0.2669376552 -0.3329478808
## [311] -0.3001245364 -0.3800446613  0.2298341739  0.1494265864 -0.2061890961
## [316] -0.0012814554 -0.2069515197 -0.2182686031 -0.0925355797  0.0090703233
## [321] -0.4022936864 -0.3499137781 -0.0008729938  0.5987465705 -0.2130683064
## [326] -0.3688417042 -0.3696519470 -0.1815966420 -0.1348889156 -0.2268756658
## [331] -0.0174789843 -0.1096642502 -0.2772387981 -0.1587752804 -0.0397558368
## [336] -0.3904484867  0.0636080556 -0.1268680919 -0.2404601751 -0.1023463286
## [341] -0.3663426812 -0.3099133684 -0.0867602765 -0.4382288067  0.0506912615
## [346] -0.5751657866 -0.2352081662 -0.1050255787 -0.0439703657 -0.3415064519
## [351] -0.1410368717 -0.3672628558 -0.2994793350 -0.1715698776  0.0299910341
## [356] -0.1636982771  0.2616431647  0.3630055148 -0.1293404077  0.0536312241
## [361] -0.0671649239 -0.3395255466 -0.3698179168 -0.4996779821 -0.4043248664
## [366]  0.0369587471 -0.2475839413  0.0473146678  0.1625310477 -0.3146374218
## [371]  0.1020623794  0.0305664198 -0.2490746985  0.2296521207 -0.2287132094
## [376] -0.0929376490 -0.2149922201 -0.1989263808 -0.3175048973 -0.1146866430
## [381] -0.0356878789  0.3946338167  0.0261666513  0.1864555549 -0.1485999481
## [386] -0.3094055176 -0.5041711482  0.1155846793 -0.1401119708 -0.2742072489
## [391]  0.1600605436  0.0703213236  0.0479887139 -0.3928628211 -0.1537174277
## [396] -0.5034329804 -0.0464003083 -0.1190937644  0.0236033910  0.2611972941
## [401] -0.4249439142 -0.2075124041  0.2358410230 -0.0457272731  0.0667976869
## [406]  0.7692449802  0.3076533700 -0.1114416720  0.2318722534  0.4919167854
## [411] -0.2174161413  0.0714074786  0.1203973208 -0.0898374594  0.3532643998
## [416]  0.0337149810 -0.2221106975 -0.3409119171 -0.1380439164 -0.2379210904
## [421]  0.8061637726 -0.0802921354  0.1420197839  0.4658317641  0.4171570399
## [426]  0.0189439112  0.0069833321  0.4100546506  0.2988706066  0.0082032852
## [431] -0.2300486985 -0.3796649308  0.4094253405  0.6208960719 -0.1327561238
## [436]  0.3453358798  0.2626489123  0.0378471940  0.1055866983 -0.2580617828
## [441]  0.5879599591 -0.2963873333 -0.0693808502 -0.0617339683  0.2787668020
## [446] -0.0552078266  0.2990170702 -0.3114024910  0.4938137866 -0.0144971463
## [451] -0.4311634779  0.6913558732  0.1600716601 -0.1318766081  0.1279346574
## [456]  0.1100167717  0.9043111064 -0.1683337135 -0.2905398447  0.0974509192
## [461] -0.2234483475  0.4651393216  0.3786302978  0.4536567779  0.5057721154
## [466] -0.3005335409  0.3968239592  0.6758563202  0.6393708553  0.2503856293
## [471]  0.1032953280  0.2124853737 -0.2113109058  0.1772942305  0.2910125186
## [476] -0.1066380615  0.4298866066  0.7085640039  0.4399671531 -0.2403340231
## [481] -0.2291462888 -0.0851747281  0.6266725342  0.8468652689  0.5005308127
## [486]  0.3180846475  0.6085334941  0.3337535087  0.1744070884 -0.0902555116
## [491]  0.4004123541  0.2915673622  0.3969178945 -0.0948466960  0.6762177600
## [496]  0.4729921847 -0.3148924491  0.8554799461  0.3825911131 -0.0208065204
## [501]  0.4908370995  0.2843899218  0.6583814496 -0.1432217870 -0.0800882661
## [506]  0.6173938400 -0.2138335548 -0.0189208765  0.5771161088 -0.0944244708
## [511]  0.0269847578  0.5384009851 -0.1977161883 -0.2825040247 -0.0443001696
## [516]  0.2994981337  0.0445112027 -0.1668204195 -0.2626138184  0.3014526941
## [521]  0.0378868205  0.1928468828  0.6395875960 -0.0227068333  0.0056115746
## [526] -0.4570159506 -0.0699817756  0.1577289413  0.4427546359  0.1778202870
## [531]  0.4910388281  0.0461857160  0.4291524369 -0.0856100749  0.0923911721
## [536] -0.0989864302  0.1855832484  0.3584979433  0.0698298991  0.3882207612
## [541] -0.3055927534  0.1389268895 -0.0769063962  0.4825749987 -0.3953394294
## [546] -0.0105635813  0.0922450876 -0.2210871335  0.2222374745  0.5292950932
## [551] -0.0329018837  0.6526896252  0.1826311308 -0.4267020502 -0.1344377776
## [556] -0.1948156831  0.1615572727  0.2014716657 -0.2000587797  0.0847205155
## [561] -0.2681008474 -0.1273819505 -0.0846663661 -0.4233696057  0.4130387351
## [566] -0.1365323623  0.3939913236 -0.2058058215 -0.0827545724 -0.3112061030
## [571] -0.1889812412 -0.0233638165  0.0725644448  0.6583650141 -0.1691334615
## [576] -0.1708301651 -0.0013974673 -0.2598644373 -0.1405533058 -0.1783417987
## [581] -0.3979969130  0.0268031579  0.4208073058 -0.1986230152  0.4570909687
## [586]  0.1762430812 -0.2405766068  0.7074079252 -0.2886628474  0.1788436684
## [591]  0.8115043746 -0.0234602280  0.2666885134  0.1063706919  0.1961312841
## [596] -0.0784695591 -0.1530200423 -0.4107193105  0.0379584738  0.5145170611
## [601] -0.1202095190 -0.2225871435  0.3602688975 -0.1768176898 -0.2567822606
## [606]  0.1698281105  0.1833693059  0.2236286395  0.4046603154  0.0132470336
## [611]  0.3389650604 -0.1473678622 -0.0726387124 -0.0912842475 -0.0318920210
## [616] -0.1741926960 -0.0046194655 -0.3865645563  0.0632743939 -0.3205729819
## [621]  0.2802022904 -0.4717022799  0.1046701094  0.1940830268  0.3466790660
## [626]  0.0973049225  0.0376477938 -0.1537643978 -0.0622111032 -0.4583682425
## [631] -0.0120614264 -0.0665031296 -0.2270952831 -0.0685884087  0.2026997070
## [636] -0.3900204028 -0.1183252227 -0.0106570728 -0.1175518404  0.7068142242
## [641] -0.4227019813  0.4946651670 -0.2379954319 -0.0817465132 -0.2607040722
## [646]  0.6405481856 -0.0267992123  0.2808724570 -0.2266719184  0.5755085292
## [651] -0.1227836512  0.1262804872 -0.0626599468  0.6634639278  0.0421784535
## [656] -0.2959750819 -0.3777561676 -0.1596390801 -0.3308140992  0.1849425410
## [661]  0.3266357063  0.5761993028 -0.0475575736 -0.1419485706  0.4362898562
## [666]  0.5746226797 -0.1071157720  0.5538749741  0.2007861179 -0.3419305173
## [671]  0.0310059600  0.6141901580 -0.0857081591  0.5011558092 -0.1843331854
## [676] -0.3613732748  0.2700812947 -0.4694665173  0.0181664171  0.6566918958
## [681] -0.0987086292 -0.2559974340  0.0084288508  0.0724894833  0.1078133441
## [686] -0.0482662835 -0.3273330534 -0.0758438601 -0.3156522927  0.0506190755
## [691]  0.4061299886  0.5576653382 -0.0030492692 -0.4028667987 -0.1606265079
## [696] -0.3210219293  0.0148817771 -0.0436782518  0.0100498029  0.5804282838
## [701]  0.2062031089 -0.2153238040  0.0128139772  0.2373272424 -0.0829256457
## [706] -0.3025349362  0.8024411687 -0.1763257321 -0.0130348257  0.0940075645
## [711] -0.2937161446 -0.1818432522 -0.1272392580  0.6116796296  0.2712334804
## [716]  0.0330939221 -0.0045522068  0.1164016005 -0.2506638240 -0.1602970428
## [721]  0.0332208974 -0.2436455539  0.2146729173 -0.1878203073  0.1066021597
## [726] -0.0950161637 -0.2851727054 -0.1052242249  0.1713270289 -0.1007364099
## [731] -0.0675487883 -0.5147280918  0.0972671444 -0.2163751762  0.1044150532
## [736] -0.0661875422 -0.0100603927  0.2771575820  0.1807517442  0.5892527385
## [741]  0.2226233435 -0.0676417750  0.0670651449  0.2326492808  0.4920775674
## [746] -0.0130324722  0.2129978133  0.0062414482  0.6496919143 -0.0594636675
## [751] -0.0055404083 -0.1465159832 -0.3752856542 -0.4991995770 -0.2122431429
## [756] -0.0868685259  0.2878857391 -0.0029133138 -0.0323584033  0.0934886249
## [761] -0.0380343209 -0.1386340586  0.2963477708 -0.0762097309  0.1832346711
## [766]  0.2340749849 -0.1348482733 -0.2015767196 -0.3223947457 -0.2443343369
## [771]  0.4884361956  0.0250089585  0.4763157313  0.3105891018 -0.3388742477
## [776]  0.4816562146  0.6837625988  0.1339710615 -0.2733482410  0.2325537173
## [781] -0.2870961039 -0.0868899419  0.3682707090 -0.2040610073  0.4630672824
## [786]  0.2879893175  0.5158664812 -0.0881256427  0.2612005888 -0.2817269066
## [791] -0.1210861909 -0.0935110825  0.5342220634  0.3214601414  0.0700859879
## [796]  0.2371554853  0.1265709601  0.1564753505 -0.3105167195 -0.0367142466
## [801] -0.2366365529  0.1521904048  0.1545355963 -0.3139790621 -0.2608833047
## [806] -0.4230355268  0.1993362074 -0.0784972338 -0.0891308305  0.0387676831
## [811] -0.4824899065 -0.1274539304  0.6617844263  0.6567388323 -0.4621514987
## [816] -0.3371429963  0.3464956331 -0.0773694380 -0.4394102417  0.1229602390
## [821]  0.8509322975  0.1563885178  0.6353344959 -0.0413407251  0.3989638508
## [826] -0.3562514553 -0.3915687141 -0.2977097348 -0.3510481158  0.4389880555
## [831] -0.0207097143  0.2710276875  0.0745661205 -0.2678628603  0.5644659486
## [836]  0.0645527843  0.2113132860  0.5398342232  0.0795206564  0.4005931559
## [841]  0.1496901588  0.7121627091  0.7389326320
## 
## $gradient_direction
##            [,1]
## [1,] -0.6408779
## [2,] -0.8605022
## [3,] -1.1235148
## [4,] -0.6378817
## [5,] -1.8913839
## 
## $PCoA_coordinates
##                     [,1]          [,2]          [,3]          [,4]
## x10MCx1146  0.2341674956  2.647632e-01 -7.973242e-02  0.0420514455
## x10MCx1176 -0.1768419147  2.915810e-02  1.065146e-01  0.0668626201
## x10MCx1206 -0.0715763443  8.650175e-02  1.123627e-01 -0.1050547603
## x10MCx1350 -0.0397112332  1.228977e-01  6.952343e-02 -0.1191661258
## x10MCx1390 -0.3254037038 -4.401007e-02 -1.468204e-01 -0.0986380119
## x10MCx1529  0.0123536644  6.887982e-02  1.123893e-01  0.1320595804
## x10MCx1563  0.2203319625  1.912200e-01 -4.577862e-01  0.0482756327
## x10MCx1585 -0.0043475697  1.622177e-01  6.278957e-02 -0.1594761511
## x10MCx1667 -0.0503629992  5.056268e-02  1.172287e-01  0.0527353268
## x10MCx1745 -0.0991200741  1.214254e-01  1.093721e-01 -0.0487081819
## x10MCx1810  0.1081209173  2.740507e-01 -1.022972e-01 -0.1796445262
## x10MCx1936 -0.2572067819  3.528629e-02  5.509668e-02 -0.1029420035
## x10MCx2044 -0.1844734830  3.003575e-02  5.100485e-02  0.0475838954
## x10MCx2066 -0.2429147880 -6.036314e-02 -3.889183e-02 -0.0058701585
## x10MCx2097  0.1246408068  2.041716e-01 -6.734671e-02 -0.1444806137
## x10MCx2262  0.2553274559  2.204099e-01 -3.965416e-01  0.0311388436
## x10MCx2294 -0.3358309887 -1.176119e-01 -2.313133e-01  0.0001836905
## x10MCx2392 -0.1562868672 -6.366222e-03  1.130146e-01 -0.0264986197
## x10MCx2550  0.2503003424  2.847059e-01 -3.614179e-01 -0.0562792717
## x10MCx2839 -0.0460464018  5.120003e-02  7.122512e-02 -0.0090481957
## x10MCx2862  0.1035934356 -3.665871e-01  3.755675e-02  0.0322165406
## x10MCx3024  0.3470373134 -1.787905e-01  1.415581e-03 -0.1063458010
## x10MCx3098 -0.1803960529 -1.635041e-01 -1.180602e-01  0.2277409809
## x10MCx3111 -0.3359765048 -1.209529e-01 -2.655097e-01 -0.0826045805
## x10MCx3144 -0.1556837934  5.524400e-03  3.253820e-02 -0.0751346926
## x10MCx3329 -0.1618151738  5.527967e-03 -6.942048e-02 -0.1068223371
## x10MCx3358 -0.2676475152 -7.076831e-02 -2.331435e-01 -0.1271916444
## x10MCx3391 -0.0839457942  1.728819e-01 -3.829543e-02 -0.2818406559
## x10MCx3419  0.3361454703 -1.458175e-01 -3.181516e-03  0.0417353813
## x13MCx1129  0.3525884243 -2.067428e-01  5.026278e-02 -0.0169033097
## x13MCx1340 -0.1001684883  7.084603e-02  1.559011e-01  0.0174875678
## x13MCx1381 -0.1457487564 -1.327236e-02  8.592795e-02  0.0021659280
## x13MCx1398 -0.2016297218 -3.059594e-02 -1.286916e-01 -0.1411874184
## x13MCx1416  0.0655779844 -1.498306e-03  6.963570e-02  0.1657061643
## x13MCx1553 -0.1587803399 -1.280462e-02  8.784935e-02  0.0632645870
## x13MCx1818 -0.1784410700 -8.481869e-02 -8.823646e-02  0.0161156336
## x13MCx2054 -0.0542397364  1.200179e-01  3.959615e-02 -0.1561262766
## x13MCx2232 -0.2914795365 -1.316881e-01 -1.638777e-01  0.0026011105
## x13MCx2282 -0.0491967148  4.513754e-02  1.462512e-01  0.1138661857
## x13MCx2401 -0.2370148780  1.305391e-02  7.706028e-02 -0.0680847826
## x13MCx2621  0.2615928780 -1.840509e-01  9.218788e-02  0.1038599408
## x13MCx2699 -0.1839494061 -2.249443e-03  1.170520e-01  0.0509302191
## x13MCx2743  0.3403976579 -3.317242e-01  3.996228e-02 -0.0739102679
## x13MCx2963 -0.2664405842 -1.161159e-01 -1.976436e-01  0.0023433586
## x13MCx2965  0.4047746251 -1.207847e-01 -1.286993e-02 -0.0093405014
## x13MCx3205  0.3672744914 -3.610553e-01 -5.498121e-02 -0.0300318414
## x13MCx3311 -0.0027401959  1.194400e-01  1.138960e-01 -0.0661443855
## x13MCx3383  0.1216890486 -3.696600e-01  3.651267e-02 -0.0545860962
## x14MCx1118 -0.2417321673  2.055693e-02  3.892642e-02  0.0342466843
## x14MCx1158 -0.0022960286  1.834333e-01  1.104626e-01 -0.0591833390
## x14MCx1190  0.0652269827  1.739408e-01  1.188201e-01  0.0317114260
## x14MCx1209  0.0619752188  1.043718e-01  1.119644e-01  0.0719745228
## x14MCx1227  0.0497528569  1.925892e-01  9.618137e-02 -0.0488509616
## x14MCx1302  0.1025351527  2.201510e-01  6.148080e-02  0.0577045412
## x14MCx1313 -0.0786387521  4.301851e-02  1.360145e-01  0.0485521657
## x14MCx1363  0.3880891557 -3.898870e-01 -5.636411e-02 -0.1510657209
## x14MCx1397  0.1531666416  1.741092e-01  4.131552e-02  0.0164565386
## x14MCx1399  0.3084118596  1.318144e-01 -9.717709e-02  0.0200935900
## x14MCx1485  0.2373122601  2.169600e-01 -4.682390e-01  0.0374689923
## x14MCx1540 -0.1362818683  9.563723e-02  1.347933e-01 -0.0248949810
## x14MCx1551  0.3069974326 -4.325140e-04  4.251993e-02  0.0555919703
## x14MCx1578 -0.1945404627  2.332414e-02  6.249080e-02 -0.0663155431
## x14MCx1583  0.0178446039  1.912816e-01  8.615922e-02 -0.0692720629
## x14MCx1612 -0.2751184808 -2.984447e-02 -1.022849e-01 -0.1364841179
## x14MCx1616  0.0378234159  1.774336e-01  9.508141e-02 -0.0481254535
## x14MCx1621  0.2111669717  1.744307e-01  1.743152e-02  0.0267522355
## x14MCx1706  0.1579475435  3.016628e-01 -6.630034e-02 -0.0813136080
## x14MCx1724 -0.0139635022  1.733473e-01  1.156112e-01  0.0277874618
## x14MCx1739  0.0584591670  2.101133e-01  5.979976e-02 -0.0537298792
## x14MCx1747 -0.1835304381  1.275771e-02  4.898787e-02 -0.0095431571
## x14MCx1768  0.2207176966  1.772181e-01  5.517552e-02  0.0340366787
## x14MCx1775  0.3313157297  2.339836e-01 -2.707566e-01  0.0265222823
## x14MCx1798  0.3213262499  1.507321e-01 -1.886078e-01 -0.0097731117
## x14MCx1910  0.1328908822  1.961912e-01  4.196111e-02  0.0618607603
## x14MCx1914  0.0099558591  1.724829e-01  5.785391e-02 -0.1004055404
## x14MCx1916 -0.1769787175  7.536353e-02 -5.779677e-03  0.0119822819
## x14MCx1929  0.3106181731  4.209445e-02 -5.076717e-02  0.1086106366
## x14MCx1940  0.2535376464  1.925911e-01 -4.448062e-01  0.0740590285
## x14MCx1943 -0.1058645542 -3.788926e-01 -6.595720e-02 -0.0915825852
## x14MCx1953  0.0996094721  2.170561e-01  1.095307e-01 -0.0749802019
## x14MCx1965  0.2186890969  2.098672e-01 -3.342081e-02  0.1253471430
## x14MCx2055 -0.2095198279 -1.962895e-02  6.382753e-02 -0.0037540506
## x14MCx2088  0.0759184570  2.299811e-01  5.760601e-02 -0.0450638203
## x14MCx2162  0.2400457701  7.396306e-02  8.468589e-02  0.0717614774
## x14MCx2193  0.3838183290 -5.292767e-02 -1.437051e-01  0.1193454826
## x14MCx2220  0.0433178202  1.923108e-01  1.111917e-01 -0.0337343781
## x14MCx2237  0.0657615709 -2.964691e-01  7.913369e-02 -0.1458251971
## x14MCx2263  0.3612130979 -1.528111e-01  4.172521e-02 -0.0934553921
## x14MCx2269  0.0701220063  2.536629e-02  8.246880e-02  0.0977755658
## x14MCx2325  0.0953516138  1.537604e-01  1.196955e-01  0.1505126925
## x14MCx2355  0.2826701637 -1.770344e-01  9.948782e-02 -0.0869143278
## x14MCx2381  0.0186425309  1.784588e-01  1.169994e-01 -0.0321468641
## x14MCx2393  0.1772876186  1.437443e-01  2.698937e-03  0.1191360777
## x14MCx2420  0.1251392831  2.357499e-02  1.126754e-01  0.2117445420
## x14MCx2429 -0.0214244106  5.053727e-02  1.577860e-01  0.0961859275
## x14MCx2437 -0.2093821904 -1.230834e-02  8.209038e-02  0.0557735265
## x14MCx2453  0.1493116865 -8.285495e-02  1.069839e-01  0.1210695497
## x14MCx2468 -0.0306047416  1.275456e-01  1.272840e-01 -0.0003345001
## x14MCx2479  0.1740146364  8.841011e-02  1.275884e-01  0.0774043739
## x14MCx2494 -0.0728455689  1.261192e-01  1.319469e-01 -0.0904504699
## x14MCx2498 -0.2286788646 -3.769715e-02  8.161330e-03 -0.0646816237
## x14MCx2510  0.1591658595  1.681061e-01 -6.271270e-02  0.1455755468
## x14MCx2563 -0.0967542007  1.190436e-01  8.215827e-02 -0.1609391656
## x14MCx2587  0.2188586639  1.124385e-02  9.313215e-02  0.0713211337
## x14MCx2601  0.2202541548  2.160799e-01 -4.426989e-01  0.0365956100
## x14MCx2641 -0.0949221759  1.564204e-01  1.143764e-01 -0.1354758979
## x14MCx2645  0.3074984044 -1.229999e-01  8.244610e-02 -0.0646705751
## x14MCx2670  0.0499102756  4.547274e-02  1.199443e-01  0.0675675859
## x14MCx2682  0.0869087819 -2.824636e-01  1.143473e-01 -0.1065707016
## x14MCx2741 -0.0825377979  8.721984e-02  1.504665e-01  0.0245223786
## x14MCx2749 -0.1563835768  7.803115e-02  7.689280e-02 -0.1595545688
## x14MCx2756 -0.1520122456  1.200905e-01  1.036310e-01 -0.0953420944
## x14MCx2818  0.1017412878  7.042631e-02  9.022968e-02  0.0594514933
## x14MCx2842  0.4659484366 -2.738063e-01 -1.011127e-01 -0.1655890269
## x14MCx2903  0.1498638786  2.383494e-01 -1.137933e-01  0.0137983256
## x14MCx2932  0.2482613445  3.018528e-01 -2.507289e-01 -0.0816794108
## x14MCx2945  0.2898418898 -2.970692e-01  7.453194e-02 -0.1233431491
## x14MCx2961 -0.0513124766  1.300924e-01  1.485617e-01 -0.0309592279
## x14MCx2968  0.1966108252  1.768757e-01 -1.262166e-02  0.1001686555
## x14MCx2979  0.2576561160  2.941377e-01 -2.469412e-01 -0.0464801814
## x14MCx2986 -0.1263208828  9.319297e-02 -1.878536e-02 -0.0477971791
## x14MCx3041  0.0223731784 -3.373711e-01  5.510263e-02 -0.1161179075
## x14MCx3050 -0.0615761647 -3.241347e-01  1.876454e-02  0.0461690731
## x14MCx3150 -0.1277994076  6.488464e-02  1.301255e-01  0.0027194227
## x14MCx3229 -0.0120658609 -8.543789e-02  6.068512e-02  0.0387499759
## x14MCx3258  0.1593758315 -6.515216e-02  1.257280e-01 -0.0207710291
## x14MCx3320 -0.2062775727 -1.170597e-02  6.682371e-02 -0.0678251470
## x14MCx3348 -0.1647403556  4.154232e-02  1.038872e-01  0.0384849541
## x14MCx3378  0.4371797357 -9.670273e-02 -1.880421e-01 -0.0068142059
## x14MCx3397  0.0371963787  1.298319e-01  1.105028e-01  0.0432164370
## x14MCx3405 -0.0046130800  6.633009e-02  9.374495e-02  0.1120679080
## x20MCx1115 -0.2959724414  1.067684e-02 -2.866321e-02 -0.1179217886
## x20MCx1122 -0.1874447758  6.435211e-02  7.899698e-02 -0.1271676537
## x20MCx1125 -0.1179464900 -8.263335e-03  4.516854e-02  0.1110274508
## x20MCx1181  0.1809579339 -3.196049e-01  9.240822e-02 -0.0756957308
## x20MCx1184 -0.1790007587  6.050919e-02  7.167759e-02  0.0194363958
## x20MCx1203 -0.3187915628 -6.670365e-02 -3.117077e-02  0.0279436815
## x20MCx1252  0.3976892970 -2.498192e-01  4.165873e-02  0.0101884066
## x20MCx1263 -0.1121749761  6.012073e-02  1.833187e-01  0.0570273286
## x20MCx1264 -0.2523540011 -2.963062e-02 -1.088646e-01 -0.0699947590
## x20MCx1278  0.0048526207  1.674142e-01  1.316905e-01 -0.0461248158
## x20MCx1332 -0.2283212877  3.658121e-02  7.126327e-02 -0.0531761862
## x20MCx1366 -0.0553921045  3.310379e-02  1.283232e-01  0.1780600957
## x20MCx1393  0.1142846568 -1.342100e-01  1.240845e-01  0.1251771242
## x20MCx1424 -0.3113966771 -7.817664e-02 -1.613192e-02  0.0522960314
## x20MCx1469 -0.0435469916  9.928363e-02  9.819211e-02 -0.0228628676
## x20MCx1478 -0.2116009533  5.734230e-02  4.925567e-02 -0.1084325724
## x20MCx1492  0.2980810323 -7.340204e-02  8.621072e-03 -0.0034927765
## x20MCx1559 -0.1594226756  2.213418e-02  1.289925e-01  0.0782947587
## x20MCx1631  0.1879659503 -2.840005e-01  1.029630e-01 -0.0657483694
## x20MCx1634 -0.1378953806  1.045840e-01 -1.254057e-03 -0.1473006669
## x20MCx1665  0.0779211067  6.103228e-02  1.215486e-01  0.1500133564
## x20MCx1673  0.2916686272 -2.764219e-01  1.662814e-02 -0.1525916068
## x20MCx1708 -0.0449155088  7.249732e-02  1.189431e-01  0.1867075727
## x20MCx1717 -0.0156035834  1.319309e-01  3.331214e-02 -0.1479671842
## x20MCx1734 -0.1011467442  3.775732e-02  1.092481e-01 -0.0894648425
## x20MCx1756 -0.0579276952  7.361979e-02  9.824437e-02  0.1597722687
## x20MCx1780  0.3252611815 -2.194951e-01  2.813960e-02 -0.0541488793
## x20MCx1790 -0.2957102045 -6.156305e-02 -8.480748e-02 -0.0688894657
## x20MCx1830  0.3574493804 -3.767243e-01  3.098039e-02 -0.0224287342
## x20MCx1837 -0.3096100663 -2.663871e-02 -9.170459e-02 -0.0972193014
## x20MCx1854 -0.2405159655  2.321605e-02 -2.508833e-02 -0.0837625321
## x20MCx1868 -0.1622128189  7.711963e-02  6.476996e-02 -0.0665665981
## x20MCx1871  0.3538696558  3.305231e-02 -4.693915e-02  0.1017308873
## x20MCx1925 -0.1692880077 -2.482464e-02  8.259560e-02  0.1784095421
## x20MCx1941 -0.1300710758  1.321710e-01  8.545991e-02 -0.0673309487
## x20MCx1959  0.2502496375  2.608499e-01 -2.449725e-01  0.0124358668
## x20MCx1986 -0.0730489326 -2.782974e-02  7.197824e-02  0.0642514777
## x20MCx2000 -0.3169046239 -5.645081e-02 -1.220839e-01 -0.0809161518
## x20MCx2016  0.0545523660 -1.413895e-03  1.346790e-01  0.1189984471
## x20MCx2024 -0.0030590640  2.422949e-02  1.288157e-01  0.1318921896
## x20MCx2039  0.0038083431  4.484945e-03  1.131906e-01  0.0396156896
## x20MCx2085 -0.3172788806 -4.154940e-02 -1.288159e-01 -0.0331862001
## x20MCx2118 -0.1572316995  2.310826e-03  1.851617e-02 -0.0388515237
## x20MCx2119  0.0247017237  1.164513e-01  7.775915e-02 -0.0205125821
## x20MCx2233  0.0316159800 -1.169035e-01  3.960119e-02  0.2715951547
## x20MCx2251  0.1431109799  2.648872e-01  1.424017e-03 -0.1303109881
## x20MCx2265 -0.2845536340  1.164901e-03 -9.232097e-03 -0.1179165655
## x20MCx2307  0.2368380954 -6.994550e-02  7.569480e-02  0.1111282499
## x20MCx2328  0.2183865513  2.917336e-01 -2.981036e-01 -0.0770360649
## x20MCx2344  0.0348676360  1.345750e-01  1.342929e-01  0.0586238281
## x20MCx2351 -0.2466233821 -2.169905e-02  4.997343e-02  0.0998152199
## x20MCx2368  0.2682884731  2.390726e-01 -1.357321e-01 -0.0186049038
## x20MCx2465 -0.1869256036 -8.808217e-02 -4.173002e-02  0.0266316159
## x20MCx2483 -0.3451839012 -7.333021e-02 -7.673836e-02 -0.0310536629
## x20MCx2542 -0.2690709786 -6.954579e-04 -4.947004e-03 -0.1125773627
## x20MCx2559 -0.2106553544 -7.902454e-03 -1.416790e-01 -0.1500719514
## x20MCx2581 -0.3080976670 -8.780157e-02 -2.814675e-01 -0.1286593038
## x20MCx2628 -0.0154732789 -1.266736e-01  8.054093e-02 -0.0091947069
## x20MCx2631 -0.1065249370  6.965600e-02  1.428321e-01  0.0755873800
## x20MCx2634  0.1892491411  1.364956e-01 -2.580853e-03  0.1359041228
## x20MCx2642  0.0328019640  1.780965e-01  1.597612e-01  0.0465828395
## x20MCx2677  0.1013602088 -3.715985e-03  1.183083e-01  0.1489516245
## x20MCx2717  0.0913310674 -1.589629e-02  8.903137e-02  0.1394734313
## x20MCx2745  0.1994127196 -3.536103e-01  3.832550e-02 -0.1969770050
## x20MCx2759 -0.1252401565  1.291207e-03  9.518756e-02  0.0783570573
## x20MCx2761 -0.2365478757  2.340883e-02  4.243849e-02 -0.0429767328
## x20MCx2773 -0.2152278739  3.332972e-02  5.739373e-02 -0.0579184293
## x20MCx2787 -0.1293189120  1.175650e-02  1.316290e-01  0.0575323191
## x20MCx2857  0.0994406129 -3.471887e-01  6.771851e-02 -0.1042801051
## x20MCx2870 -0.2070235477  8.791960e-04  6.208705e-02  0.0151602329
## x20MCx2885 -0.0852019916  4.172839e-02  6.766469e-02 -0.0779316706
## x20MCx2895  0.1620083733 -2.331265e-02  9.031890e-02  0.0223471155
## x20MCx2896  0.1973712307 -2.000984e-01  1.241330e-01  0.0139174613
## x20MCx2929 -0.3229102715 -5.736916e-02 -1.488425e-01 -0.0972233200
## x20MCx2969 -0.0890868726  1.179230e-01  1.498571e-01  0.0279337616
## x20MCx2975 -0.3185590840 -6.164572e-02 -1.642248e-02 -0.0034889364
## x20MCx2988 -0.1967937440  7.180774e-02  3.159886e-02 -0.1543751415
## x20MCx3020 -0.3248582835 -3.925566e-02 -1.614444e-01 -0.1297160030
## x20MCx3044  0.1055475959  3.478756e-02  1.035991e-01  0.0831761453
## x20MCx3048 -0.1569658036 -3.351283e-02  1.019855e-01  0.0340729741
## x20MCx3094 -0.1782292728  8.295349e-02  2.271812e-02 -0.1857547099
## x20MCx3099 -0.1831058108 -2.471530e-02  7.622583e-02  0.1613717265
## x20MCx3108 -0.2295150409 -2.028543e-02 -4.803359e-02  0.0672433180
## x20MCx3119  0.1421010486 -1.063388e-01  1.232278e-01  0.0911851662
## x20MCx3228 -0.2527271463 -1.638974e-02 -1.465065e-03  0.0074701899
## x20MCx3241 -0.1279380421  5.380390e-02  2.840611e-02  0.0127745099
## x20MCx3308 -0.0420909088  1.029060e-01  9.670041e-02 -0.0361660425
## x20MCx3335 -0.1269718137  8.592133e-02  9.717634e-02  0.0250446878
## x20MCx3337 -0.0863444760  7.065169e-02  1.421831e-01  0.1011844118
## x20MCx3402  0.1355242502  8.837394e-02  3.095543e-02 -0.1985648587
## x30MCx1112 -0.2332425650 -7.435265e-03 -2.636378e-02 -0.1093971919
## x30MCx1116  0.2905245174 -3.404027e-02  2.433654e-05  0.2105072446
## x30MCx1163  0.1904889636 -7.179421e-02  1.454372e-01  0.0772505306
## x30MCx1170  0.1021412819  1.200003e-01  9.606140e-02 -0.0244000630
## x30MCx1172 -0.2374501972  4.266675e-02  6.208196e-02 -0.0725721837
## x30MCx1180 -0.2061080366  5.910659e-02  1.773172e-02 -0.1300516293
## x30MCx1193  0.2090966749  1.744525e-01 -3.700621e-02  0.0737252396
## x30MCx1196 -0.0244375353  1.632147e-01  6.763652e-02 -0.0097086530
## x30MCx1201  0.2362224633  4.661535e-02  1.071219e-01 -0.0224063113
## x30MCx1226 -0.0339888910  1.532389e-01  9.156889e-02  0.0651358045
## x30MCx1235 -0.1864713903  2.822258e-02  1.387226e-01  0.0060635205
## x30MCx1259  0.1339787452  7.364939e-04  1.459204e-01 -0.0375249563
## x30MCx1266  0.2802120998  2.926287e-01 -3.489713e-01  0.0067167839
## x30MCx1270 -0.0658483532  5.447471e-02  1.253271e-01  0.1351894007
## x30MCx1280  0.0239640314  2.459613e-01 -9.312523e-02 -0.2203514462
## x30MCx1308  0.0022454308  1.354015e-01  8.372289e-02  0.1131649600
## x30MCx1314  0.3055803338 -3.067292e-02  4.582917e-02  0.0497711821
## x30MCx1321  0.3427210781 -3.907973e-02  4.508163e-02 -0.0250949136
## x30MCx1335 -0.0072312147  9.566920e-02  1.215851e-01  0.0331518448
## x30MCx1394 -0.3220199713 -1.171449e-01 -1.730404e-01 -0.0376783089
## x30MCx1405  0.0167487643  8.158647e-02  1.283411e-01  0.2578069893
## x30MCx1415 -0.1099408896  1.753925e-01  5.360771e-02 -0.1398562179
## x30MCx1417 -0.0286744779  1.365030e-01  1.078642e-01 -0.0174939280
## x30MCx1451  0.2894139809  1.511830e-01 -4.433288e-02  0.1119112561
## x30MCx1479  0.1276860819 -3.940558e-01  1.388093e-02  0.0639649946
## x30MCx1503 -0.0263421357  1.492193e-01  7.552682e-02 -0.0635476437
## x30MCx1517 -0.2810130380 -1.053596e-01 -1.262508e-01  0.1346547445
## x30MCx1527  0.1847361969 -2.114585e-01  1.158502e-01 -0.0065473233
## x30MCx1556  0.0828153691  1.687981e-01  1.174534e-01  0.0600603816
## x30MCx1566 -0.0380548614 -3.429266e-03  1.154310e-01  0.1808442017
## x30MCx1569 -0.0573733723  1.510931e-01  1.203627e-01 -0.0107746144
## x30MCx1586 -0.0548769474  1.463674e-01  1.015962e-01 -0.0536214138
## x30MCx1597 -0.0835090704  6.762737e-02  1.234024e-01  0.1088388392
## x30MCx1601  0.2758055593 -2.523135e-01  8.071008e-02 -0.1340217394
## x30MCx1611  0.0313851910  9.292631e-02  1.303319e-01  0.0986112605
## x30MCx1618  0.2722385296 -2.462773e-01  9.486901e-02 -0.1346193635
## x30MCx1636  0.3683337111  9.983124e-02 -1.372005e-01  0.0577520182
## x30MCx1637  0.3023080501 -1.640604e-01  8.891370e-02 -0.0941266525
## x30MCx1646  0.1479892345  1.736249e-01  4.707354e-02  0.0924545447
## x30MCx1649  0.1346014600  2.381873e-01  7.257355e-03 -0.1113753297
## x30MCx1664 -0.1167477593  9.813794e-02  1.224117e-01 -0.1157663982
## x30MCx1712  0.0714668985  1.844948e-01  6.343925e-02 -0.0933958552
## x30MCx1722 -0.1755415061  1.061177e-01  3.545957e-02 -0.1675005575
## x30MCx1744  0.1410743154  1.508826e-01  1.052735e-01  0.0060628540
## x30MCx1748 -0.1422558394  1.018494e-01  9.484551e-02 -0.1081190252
## x30MCx1774  0.3476550805  1.970598e-02  9.846791e-03  0.0566522856
## x30MCx1782  0.2632341447  6.224061e-02  1.031408e-02 -0.0540999564
## x30MCx1786 -0.2531131216 -2.805340e-02  3.908329e-02  0.0170354003
## x30MCx1787  0.0314002153 -6.082053e-02  1.304058e-01  0.0939749267
## x30MCx1791  0.2444495236  1.828526e-01 -1.559072e-01  0.1847263682
## x30MCx1792 -0.0506163189  1.467231e-01  7.452336e-02 -0.0782793940
## x30MCx1824  0.0996590845  7.846511e-02  9.329537e-02  0.0815296254
## x30MCx1828  0.0129892319  2.245129e-01  7.885761e-02 -0.0346240962
## x30MCx1860  0.3484142959 -3.172806e-02  3.835375e-02  0.0051868974
## x30MCx1872  0.1520172393  1.681197e-01  4.542253e-02  0.2021786830
## x30MCx1881 -0.1456882616 -1.186571e-02  9.436070e-02  0.1464366876
## x30MCx1911  0.1622552928 -3.664347e-01  6.074276e-02  0.0377978068
## x30MCx1917 -0.2001891435 -3.271750e-02  4.829126e-02  0.1090603428
## x30MCx1966 -0.0898149573  1.334470e-01  1.119994e-01 -0.0585318555
## x30MCx1972  0.3747722577 -1.834645e-01 -1.693918e-02  0.0823577748
## x30MCx1980  0.2699622881 -2.929072e-01  5.976658e-02 -0.1056326327
## x30MCx1993  0.1796540969  1.245150e-01  2.990018e-02  0.1826540164
## x30MCx1996 -0.1225178908  1.178500e-01  8.501125e-02 -0.0704459951
## x30MCx2009 -0.1042191284  9.584053e-02  1.184014e-01 -0.0125019053
## x30MCx2015  0.2216082288  9.288480e-02 -4.781839e-01  0.0571057318
## x30MCx2022  0.3297454425  1.642592e-01 -1.230633e-01  0.1178992691
## x30MCx2041  0.2200231586  2.925190e-01 -8.593027e-02 -0.0394796661
## x30MCx2081  0.0931896243  1.981877e-01  1.110724e-01  0.0787699293
## x30MCx2092 -0.2547253321  2.277653e-02 -3.332599e-03 -0.1859623488
## x30MCx2096 -0.0013585814  5.138808e-02  5.104355e-02  0.2142561612
## x30MCx2099  0.1173744531  1.889380e-01  1.297663e-01  0.0319009637
## x30MCx2107  0.0450323983  1.909092e-01 -7.470788e-03  0.0205335865
## x30MCx2131 -0.2459201736 -5.857487e-02  5.699097e-02  0.1064009749
## x30MCx2132 -0.0746345213  9.761477e-02  1.155960e-01 -0.0470660047
## x30MCx2140  0.2741148727  9.646853e-02  2.476097e-02 -0.0151397428
## x30MCx2149  0.2198453734  4.126118e-02  7.004815e-02 -0.0203250989
## x30MCx2158  0.0709746784  1.547682e-01  5.592168e-02 -0.1587859720
## x30MCx2166  0.2156515758  2.569749e-01 -2.932076e-02  0.0617124106
## x30MCx2168  0.1453551389  2.998958e-01 -6.728998e-02 -0.0653805276
## x30MCx2179 -0.0553967053 -7.677047e-02  1.221151e-01  0.2201103130
## x30MCx2183 -0.0958765260  1.712881e-02  1.401565e-01  0.0340949519
## x30MCx2201  0.0279292786  1.751188e-01  8.808854e-02  0.0733374766
## x30MCx2204  0.2618926160 -3.286619e-01  2.455090e-02 -0.1813946963
## x30MCx2206 -0.2610671709  1.477641e-02 -6.017297e-02 -0.1830540333
## x30MCx2257  0.1767856723  6.727833e-02  1.001995e-01  0.0403357044
## x30MCx2281  0.2829207312  2.336576e-01 -1.222656e-01  0.0573579346
## x30MCx2298  0.0699436039  1.847041e-01  1.281803e-02 -0.1127356165
## x30MCx2312  0.0826172107  2.400958e-01  5.558294e-02 -0.0193626094
## x30MCx2316  0.1056972997  3.063298e-01  1.654952e-02 -0.1108005163
## x30MCx2327  0.0750284914  2.302859e-01  7.823801e-02  0.0359459958
## x30MCx2334  0.0124522917  1.841712e-01  1.221549e-01 -0.0272580184
## x30MCx2349 -0.2163681755  6.001245e-02  4.562118e-02 -0.0207017039
## x30MCx2352 -0.1939749727  6.506950e-02  4.733751e-02 -0.0780561313
## x30MCx2353  0.2947102766  1.281907e-01 -1.527148e-02  0.1383179643
## x30MCx2354 -0.1437165663  4.249606e-02  6.568165e-02 -0.0416178577
## x30MCx2363 -0.0387943896  1.144293e-01  9.552153e-02 -0.0190508708
## x30MCx2414  0.0720224022  1.267478e-01 -2.475263e-02  0.1063267544
## x30MCx2415  0.2137840924  1.084217e-01  7.009960e-02  0.0745843357
## x30MCx2423  0.2769814632 -9.753613e-02  1.184378e-01 -0.0107330561
## x30MCx2425 -0.0529495981  8.027725e-02  1.161030e-01 -0.0259514668
## x30MCx2445  0.2707717670  2.892799e-01 -1.971302e-01  0.0039389543
## x30MCx2450  0.0476012320 -2.779537e-01  7.193860e-02 -0.0258394211
## x30MCx2451 -0.2552465892  6.453978e-02 -8.397199e-02 -0.1833940924
## x30MCx2473 -0.1348107419  8.226083e-02  1.130729e-01 -0.1038815867
## x30MCx2480 -0.0218473958  4.368933e-03  1.430615e-02  0.1616233888
## x30MCx2499 -0.0255026426  1.112806e-01  1.236578e-01  0.0487742718
## x30MCx2501  0.2245770805 -2.305980e-02  9.241913e-02  0.0640925445
## x30MCx2529  0.2407977873  3.324184e-02 -1.034745e-02  0.2042510834
## x30MCx2543 -0.1348413607  7.772989e-02  1.288552e-01 -0.0104686582
## x30MCx2568  0.2763476844 -9.096653e-02  1.165837e-01 -0.1172160533
## x30MCx2570 -0.1685469945  7.219617e-02  7.889011e-02 -0.1458308701
## x30MCx2573  0.1681859917  2.446397e-01  1.583854e-02  0.1331911588
## x30MCx2574 -0.0661636161  1.018113e-01  7.224616e-02  0.0591259330
## x30MCx2605  0.0116053008  7.415746e-02  5.310395e-02  0.0511967091
## x30MCx2619  0.0778649242  1.048594e-01  9.224224e-02 -0.0199670740
## x30MCx2654  0.3909050543 -3.828482e-01 -4.154619e-02 -0.1244264948
## x30MCx2661 -0.0149995553  1.508356e-01 -1.836233e-02 -0.1754580299
## x30MCx2662  0.0630767082  2.315781e-01  7.592899e-02  0.0123659197
## x30MCx2675 -0.0053521798 -7.922022e-02  1.653660e-01  0.0410524445
## x30MCx2676  0.1019102817  7.460473e-02  2.194354e-02 -0.0129751227
## x30MCx2700  0.0387445913  1.864823e-01  1.369864e-01  0.0206020038
## x30MCx2708 -0.2032189297 -1.380377e-02  5.594775e-02  0.0107383366
## x30MCx2720  0.2180864072  2.801180e-01 -7.678293e-02 -0.0687033083
## x30MCx2735 -0.1707487109  7.241766e-02  8.727024e-02  0.0097049044
## x30MCx2746  0.1326425390  1.663466e-01  8.833294e-02  0.0908411051
## x30MCx2760 -0.0745562134  9.559587e-02  1.445036e-01  0.0848487008
## x30MCx2770 -0.0608173951 -1.381409e-01  3.638556e-02  0.1850293949
## x30MCx2775 -0.2324788986 -3.089891e-03  9.939181e-02  0.0588573428
## x30MCx2777  0.0561982177  1.444007e-01  1.248029e-01  0.0624603093
## x30MCx2783  0.1066794438  2.448329e-01 -2.883105e-02 -0.0135065724
## x30MCx2790  0.0023828635  1.578471e-01  1.500359e-01 -0.0317512696
## x30MCx2811  0.1854689423  1.802665e-01  1.787157e-02  0.0903411230
## x30MCx2819  0.2796476014  2.577441e-01 -2.825656e-01  0.0792662932
## x30MCx2822 -0.1208784524  1.335129e-01  3.543855e-02 -0.1963616023
## x30MCx2828  0.0006973415  1.340079e-01  9.609628e-02  0.0169331306
## x30MCx2840  0.3663300641 -4.955444e-02 -1.773717e-01  0.1565089147
## x30MCx2881 -0.0871210736  2.178171e-02 -1.049328e-02 -0.2143826917
## x30MCx2909  0.3393563974  1.635848e-01 -1.472971e-01  0.1104086584
## x30MCx2911 -0.2070972180  5.930408e-02  9.649720e-02 -0.0552673753
## x30MCx2920  0.3108237654 -3.409161e-01  2.750773e-02 -0.1012890913
## x30MCx2941 -0.1304631026  1.657391e-02  1.126505e-01  0.1226570973
## x30MCx2954  0.0355963405  7.655676e-02  7.519888e-02  0.0789029726
## x30MCx2966 -0.0277857733  1.091817e-01  1.534690e-01  0.0635092516
## x30MCx2990 -0.0563404501  5.540136e-02  1.288681e-01  0.0927922190
## x30MCx2995 -0.1104269294  1.638909e-01  7.538217e-02 -0.1018449475
## x30MCx3000 -0.0575801201  7.124548e-02  1.464504e-01 -0.0222852430
## x30MCx3017  0.2618167566 -2.738843e-01  6.967315e-02 -0.1629253376
## x30MCx3025 -0.1240243453  1.203367e-01 -8.887524e-03 -0.1738147736
## x30MCx3030 -0.0587675623  1.000799e-01  1.406898e-01 -0.0249770091
## x30MCx3058  0.2813122040 -3.353015e-01  2.031345e-02 -0.1820795723
## x30MCx3061 -0.1186717996  1.218408e-01  8.143216e-02 -0.0600136098
## x30MCx3065 -0.0461020486  5.152933e-02  1.125048e-01  0.1989137915
## x30MCx3070 -0.2390076199  6.223827e-02  3.296816e-02 -0.1793527929
## x30MCx3083  0.1803528883  1.140599e-01  1.789375e-02 -0.0086476949
## x30MCx3086 -0.1556356739  8.946787e-02  1.173650e-01 -0.0930088112
## x30MCx3091  0.0173294890  1.580924e-01  1.030784e-01  0.0850008817
## x30MCx3100  0.2138649912  1.368335e-01 -5.209359e-02  0.2237989040
## x30MCx3103  0.2463707124  2.246600e-01 -1.453396e-01  0.0735894180
## x30MCx3118  0.0334987037  2.431621e-01  2.122880e-02 -0.0689874109
## x30MCx3128  0.2014136209  1.317059e-01 -5.413531e-02 -0.0038038471
## x30MCx3140 -0.0212075519  2.215071e-02  5.316056e-02 -0.1493208991
## x30MCx3152 -0.1970467168  4.456815e-02  6.981767e-02 -0.0454138402
## x30MCx3160  0.3179012908  1.089585e-01 -4.499956e-01  0.0415969856
## x30MCx3171 -0.1803810119  2.035296e-03  7.565288e-02  0.0339905096
## x30MCx3180 -0.0465193949  1.323491e-01  1.599793e-01 -0.0291244926
## x30MCx3183  0.1478363039  1.538264e-01  4.829459e-02  0.0883876415
## x30MCx3214 -0.1554079947  9.220897e-02  8.294842e-02 -0.0933927123
## x30MCx3221 -0.1385322301  3.525191e-02  1.247623e-01 -0.0239755618
## x30MCx3237 -0.0424521843  1.123647e-01  1.058947e-01 -0.0099248066
## x30MCx3240  0.3820057751 -3.061031e-01 -3.591663e-02 -0.1002108106
## x30MCx3243  0.2880910031 -3.338382e-01  5.273742e-04 -0.1925153793
## x30MCx3263 -0.1621786534  4.027948e-02 -2.169945e-02 -0.0999056530
## x30MCx3291  0.1179389516  1.664256e-01  8.729463e-02  0.0781091684
## x30MCx3314  0.2387397625  2.158321e-01 -4.478592e-01  0.0225278850
## x30MCx3340  0.0445004199  1.801222e-01  9.296893e-02 -0.0612069325
## x30MCx3345  0.1692260296  9.402377e-02  9.221331e-02  0.0383072365
## x30MCx3366  0.0041069399  5.588451e-02  1.290973e-01  0.1805080621
## x30MCx3369  0.3410742712  1.292708e-01 -6.723277e-02 -0.0732443015
## x30MCx3375 -0.2175185965  1.796703e-02  4.581588e-02  0.0459640238
## x30MCx3376 -0.0044405026  1.253483e-01  1.595219e-01  0.0666463909
## x30MCx3379 -0.1718539546 -2.589606e-02  1.024246e-01  0.1860266225
## x30MCx3384  0.3700016881 -1.553965e-01 -4.108408e-03 -0.0067390807
## x30MCx3414  0.3071382425 -2.322687e-01  9.744444e-02 -0.1013384213
## x10MCx1135  0.2795391761 -3.868316e-01  3.548456e-03 -0.0942688561
## x10MCx1144 -0.2386884659 -6.416068e-02 -2.655056e-01 -0.1583854490
## x10MCx1155  0.3554995915 -1.384822e-01 -7.392517e-02  0.0280668465
## x10MCx1165 -0.1643343513 -1.305622e-02  7.037603e-02 -0.0212746329
## x10MCx1208 -0.2505402317 -3.299959e-02 -7.531881e-03 -0.0731567958
## x10MCx1229 -0.2705562814 -1.244669e-01 -1.566086e-01 -0.0328606253
## x10MCx1256 -0.0794097958 -2.556440e-02  1.029268e-01  0.1194397146
## x10MCx1273  0.1938243432 -3.120800e-01  4.651062e-02 -0.2049359195
## x10MCx1291 -0.0822357765  7.065937e-02  6.023261e-02 -0.0168289410
## x10MCx1318 -0.1715968024 -1.636669e-03  7.438867e-02  0.1012700450
## x10MCx1330 -0.2674801300 -3.354036e-02 -6.277068e-02 -0.0463171353
## x10MCx1333  0.1764752982 -3.178345e-01  6.571036e-02 -0.1713032952
## x10MCx1344  0.0237386877  1.671533e-02  7.064533e-02  0.1419976810
## x10MCx1365  0.0118114268  2.048190e-01  5.103383e-02 -0.1765209908
## x10MCx1395  0.1119203866 -1.186072e-02  1.315022e-01  0.0758888955
## x10MCx1414  0.0916883203  6.119152e-02  6.268107e-02  0.1582001434
## x10MCx1431 -0.3129018704 -4.738063e-02 -2.472519e-01 -0.1764342412
## x10MCx1450 -0.2183850666 -1.271076e-02  1.092120e-01  0.0099522959
## x10MCx1494 -0.2485700066 -5.304780e-02 -8.326702e-03 -0.0483711360
## x10MCx1530 -0.3083169598 -1.127998e-01 -1.209398e-01  0.0108928311
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## x10MCx1633  0.0714095527 -3.198632e-02  8.809927e-02  0.0461584086
## x10MCx1643 -0.1357572632  4.875312e-02  2.236326e-02 -0.1117931206
## x10MCx1668 -0.3083229799 -3.322736e-02 -4.265157e-02 -0.1288617455
## x10MCx1678  0.0102957139 -2.225997e-01  6.567601e-02 -0.1915683119
## x10MCx1685 -0.0017981928 -1.757012e-02  1.244134e-01  0.0533223725
## x10MCx1755  0.2738195953  2.447334e-01 -3.802876e-01  0.0062338195
## x10MCx1778 -0.0272282487  1.115664e-01  1.555716e-01  0.0348411642
## x10MCx1785 -0.2813413594 -4.685523e-02 -1.113621e-01 -0.1445674923
## x10MCx1859 -0.2505449215 -2.312020e-02 -1.508485e-01 -0.1024099830
## x10MCx1877  0.1943454149 -2.584759e-01  9.565114e-02 -0.0234575828
## x10MCx1906 -0.2140834941 -1.133633e-01 -4.416744e-02  0.0330881355
## x10MCx1946 -0.1786053804  2.991677e-02  2.849868e-02 -0.0390984637
## x10MCx2003  0.0595854324  1.235688e-02  8.621732e-02  0.0201645038
## x10MCx2012 -0.0801531626  1.934407e-01 -7.909820e-02 -0.2980382373
## x10MCx2028 -0.1096786987  2.046401e-02  1.344325e-01  0.0531070176
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## x10MCx2060  0.2607361138 -1.708084e-01  1.280300e-01 -0.0737391179
## x10MCx2070 -0.1463211664  1.472007e-02  8.031395e-02  0.0324295723
## x10MCx2157 -0.1887113927 -1.010036e-02  2.267522e-02 -0.0721970905
## x10MCx2169 -0.1715014832  2.658143e-02  6.449214e-02 -0.0967213724
## x10MCx2176 -0.2277284723  1.620352e-02 -2.275458e-02 -0.1283745995
## x10MCx2177 -0.0161850605  9.024982e-02  1.232272e-01  0.1297539530
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## x11MCx2713 -0.2568217824  4.822954e-02 -9.790759e-02 -0.2067864720
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## x12MCx1788  0.1164099107  2.214952e-01  8.532108e-02  0.0740233504
## x12MCx1836 -0.0072989132  3.092275e-02  1.287570e-02  0.2026769881
## x12MCx1869  0.0546693893 -1.225301e-01  1.377226e-01 -0.1803975754
## x12MCx1886  0.2364673276  2.458185e-01 -1.066593e-01 -0.0189408321
## x12MCx1893 -0.2891346139 -1.252826e-01 -9.006283e-02  0.1606136440
## x12MCx1895 -0.1436121574 -1.863650e-01 -1.791822e-02 -0.1490640489
## x12MCx1903 -0.1391776275 -7.076778e-03  7.502619e-02  0.1605260111
## x12MCx1909 -0.3222107225 -8.790545e-02 -1.611596e-01 -0.0929598952
## x12MCx1922 -0.1331731186  3.175657e-03  7.210909e-02 -0.0672189602
## x12MCx1988  0.0977996698  1.901302e-02  1.022580e-01  0.2583485773
## x12MCx2002  0.1661898523 -3.219649e-01  9.105254e-02 -0.0672421379
## x12MCx2109  0.2710299920  2.465250e-01 -3.384029e-01 -0.0029903532
## x12MCx2111 -0.2482822763  2.489294e-02  3.361758e-02 -0.0895589428
## x12MCx2136  0.3967669946 -2.761055e-01 -1.415896e-02 -0.1582574032
## x12MCx2185 -0.1764701788  8.131013e-03  6.905371e-02  0.0245008767
## x12MCx2202 -0.0474025213 -3.184777e-01 -7.886592e-02  0.1643893506
## x12MCx2212 -0.1208743007  3.833117e-02  8.393599e-02 -0.0678561226
## x12MCx2259 -0.0204065788  1.992292e-01  9.663575e-02 -0.0742679790
## x12MCx2285 -0.1848129449 -1.150885e-01  4.916198e-03  0.1790292143
## x12MCx2291  0.1315486205  2.488478e-01  5.408383e-02 -0.0664262814
## x12MCx2317 -0.2653218144 -6.199983e-02 -5.462186e-02 -0.0321712578
## x12MCx2321 -0.0270886611 -6.302035e-02  2.968844e-02  0.0322205564
## x12MCx2323 -0.1262232879 -1.228804e-02  1.820520e-02 -0.0135915293
## x12MCx2347 -0.1144012330  9.705335e-02  1.172694e-01 -0.0699726369
## x12MCx2380  0.2486211603 -4.164802e-01 -6.423829e-02  0.0525296796
## x12MCx2447  0.1477347153  2.548898e-01 -1.254624e-01 -0.1782630054
## x12MCx2454  0.0293321027  2.276713e-01  9.812478e-03 -0.2370419460
## x12MCx2489 -0.2283947017 -2.046089e-02  5.731759e-02  0.0175887343
## x12MCx2496  0.0116000981 -2.456712e-01  1.177863e-01 -0.1369988513
## x12MCx2522 -0.2462510297 -1.608902e-01 -3.253887e-01  0.1728462892
## x12MCx2530  0.1206868021  1.664805e-02  5.418440e-02  0.1740177878
## x12MCx2576  0.2223612741 -2.932243e-01  1.246039e-01  0.0008235715
## x12MCx2667  0.1840930221 -1.194616e-01  1.250857e-01  0.0964965136
## x12MCx2701 -0.1061050322  6.158347e-02  1.035702e-01 -0.0354125111
## x12MCx2736  0.0125254296 -5.148585e-02  1.563618e-01  0.0620021577
## x12MCx2763  0.2719738917  2.615685e-01 -2.365761e-01  0.0338182641
## x12MCx2778  0.0100878183  7.577301e-02  1.030257e-01  0.1534928172
## x12MCx2798  0.0969203519 -3.221378e-01  5.274216e-02 -0.1427153254
## x12MCx2993  0.4620864085 -2.278967e-01 -1.467845e-01 -0.1794878644
## x12MCx3006  0.1055519926 -8.322724e-02  1.459641e-01  0.1218165764
## x12MCx3026  0.3582921713 -4.418391e-02 -3.407275e-01  0.0278819364
## x12MCx3046 -0.2495457068 -8.755045e-04  5.955107e-02 -0.0184062169
## x12MCx3072  0.0673530622  1.053555e-01  9.210427e-02  0.1547146338
## x12MCx3082 -0.0952850308 -7.649766e-02 -6.888008e-02 -0.1768328676
## x12MCx3113  0.1471492671  1.524948e-01  4.831488e-02  0.1680507930
## x12MCx3117 -0.1291747387  3.187485e-02  8.177911e-03  0.0083982830
## x12MCx3125 -0.2846470593 -1.465824e-02 -1.541502e-01 -0.0164312657
## x12MCx3230 -0.0418669167  2.009027e-01 -1.279894e-01 -0.2838640162
## x12MCx3272  0.4303975012 -3.846728e-01 -6.463169e-02 -0.0943074810
## x12MCx3309 -0.0321236484 -3.282540e-01 -1.233283e-01  0.1848278929
## x12MCx3333 -0.0078873763 -1.709660e-01  5.081413e-02  0.0158099924
## x12MCx3342 -0.0752638025  1.380778e-01  1.646045e-02 -0.0645359160
## x12MCx3344 -0.1493447774  2.626007e-02  1.163376e-01 -0.0513532319
## x12MCx3380 -0.0187955349  5.513006e-02  1.429299e-01  0.0464534693
## x12MCx3392  0.2804875641 -2.152487e-01 -1.059407e-02  0.1551680342
## x12MCx3424 -0.3371296254 -1.275584e-01 -1.480859e-01 -0.0138932445
## x13MCx1175  0.0939237875 -2.115613e-01  1.391646e-01  0.0624751544
## x13MCx1231  0.0050277754 -4.197250e-02  1.674226e-01  0.0100679338
## x13MCx1299 -0.2268661830  8.319761e-02 -1.528814e-02 -0.2418758854
## x13MCx1419  0.0283320044  1.918451e-01  4.131451e-02 -0.0485751081
## x13MCx1506  0.1491929899  1.545050e-01  2.609462e-02  0.1273435991
## x13MCx1608  0.1051676653  5.453850e-02 -3.147642e-01  0.0646435557
## x13MCx1783  0.3413055745 -3.124235e-01  1.408914e-02 -0.0724823391
## x13MCx1887 -0.0226698411 -1.071037e-01 -1.517147e-02  0.0360713635
## x13MCx2071 -0.1009899992 -1.373465e-01 -3.317776e-01  0.1914568937
## x13MCx2129  0.2316980677 -3.544165e-01  3.628710e-02 -0.1734372047
## x13MCx2229 -0.2766907260 -5.120554e-02  1.842066e-03 -0.0173535832
## x13MCx2582  0.0938747743  2.644021e-01 -2.997851e-03 -0.0869044045
## x13MCx3092  0.3420431063 -3.108299e-01  4.206210e-02 -0.1357817314
## x13MCx3274  0.2269143375 -1.871292e-01  8.647785e-02  0.0240142491
## x13MCx3399 -0.1237042730  5.938563e-02  7.328512e-02  0.0233848788
## x14MCx1338  0.0812722702 -7.850365e-02  1.503051e-01  0.0186751681
## x14MCx1407 -0.1948337879  1.493529e-02  1.052369e-01  0.0767088454
## x14MCx2102 -0.0361899413  1.034199e-01  1.075546e-01 -0.0753970515
## x14MCx2875  0.3412761766 -3.502348e-01  6.287868e-04 -0.1488240533
## x30MCx1130 -0.0264376505  1.304355e-01  1.224834e-01  0.0073646453
## x30MCx1137  0.3779875075 -5.595455e-02 -8.997954e-02 -0.0755755791
## x30MCx1139  0.0844431305  2.077365e-01  1.059266e-01 -0.0177156818
## x30MCx1169 -0.1059314323 -1.975110e-01 -1.524231e-01  0.3094069644
## x30MCx1183 -0.1478350588  1.261851e-01  3.649728e-02 -0.0540072352
## x30MCx1188 -0.3033095315 -1.346706e-01 -6.425079e-02  0.0958218686
## x30MCx1195  0.3881599225 -2.162254e-01  3.605650e-02 -0.1048701944
## x30MCx1197  0.0615287950 -3.139724e-01  9.932984e-02 -0.1211891018
## x30MCx1199  0.0224024291 -2.531511e-02  1.361203e-01  0.0563847752
## x30MCx1210  0.2379694283 -2.126277e-01  1.237912e-01 -0.0428463893
## x30MCx1214 -0.0199136804  3.897268e-02  1.616313e-01  0.2402418181
## x30MCx1217 -0.1824880162  4.840498e-03  3.956042e-02  0.0801337287
## x30MCx1248 -0.0423355251  1.491088e-01  9.323892e-02  0.0032827901
## x30MCx1253  0.1974231097  2.772728e-01 -2.322820e-01 -0.0422768590
## x30MCx1262 -0.2214561924  2.575016e-02  9.293107e-02 -0.0415326718
## x30MCx1271  0.2741514902 -3.216810e-02  2.531812e-02 -0.1149613306
## x30MCx1276  0.2119357942  2.815389e-01 -8.308153e-02 -0.0689435087
## x30MCx1293  0.1579553883 -2.933827e-01  1.066381e-01 -0.1082922478
## x30MCx1296 -0.1791147854  1.846836e-03  9.126162e-02  0.0554552678
## x30MCx1312  0.0256601253  2.264402e-01 -5.467216e-02 -0.2246502009
## x30MCx1331 -0.3335222766 -1.494506e-01 -2.352081e-01  0.0927154496
## x30MCx1346 -0.0519531494  3.253904e-02  1.343848e-01  0.0627591259
## x30MCx1358 -0.2910910272 -1.866241e-02 -5.324516e-02 -0.0735113678
## x30MCx1370  0.1568816780  1.412747e-01  4.051968e-02  0.1847865490
## x30MCx1372 -0.0362456516  1.060824e-01  6.257915e-02 -0.1331905715
## x30MCx1380  0.2308197177  2.549269e-01 -2.695445e-01 -0.0377826703
## x30MCx1400 -0.2337392710  6.640279e-02 -1.221410e-01 -0.2332557442
## x30MCx1401 -0.0989468133 -2.141341e-02  7.982245e-02  0.0926838806
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## x30MCx1425 -0.1403288751  6.463874e-02  1.125222e-01 -0.0694001664
## x30MCx1430 -0.2213937002 -2.414737e-01 -2.328084e-01  0.1728490728
## x30MCx1449 -0.1495938319 -1.542672e-02  8.501519e-02  0.0753113503
## x30MCx1452 -0.2168335471 -2.642632e-02  1.157263e-02  0.1234140608
## x30MCx1461  0.0867945554 -3.435854e-01 -1.085382e-01  0.1300668666
## x30MCx1474 -0.3001328830 -1.692277e-01 -2.813002e-01  0.1534892840
## x30MCx1477 -0.1272986170  7.485546e-02  1.344914e-02 -0.0081535495
## x30MCx1509  0.1875610315  2.572039e-01 -9.513957e-02  0.0360090136
## x30MCx1522  0.0800041433  2.144762e-01  1.237979e-01  0.0597913799
## x30MCx1524  0.2070541414  8.791935e-02  5.179003e-02  0.1306770130
## x30MCx1525 -0.0055793356  1.373332e-01  1.475155e-01 -0.0276388721
## x30MCx1544 -0.0392189526 -3.382654e-01 -1.164657e-01  0.0469274964
## x30MCx1554 -0.2192050621 -9.577745e-02 -1.043943e-01  0.2493040711
## x30MCx1573 -0.3233377876 -5.078325e-02 -8.824079e-02 -0.0580216264
## x30MCx1575  0.2722412269 -1.829769e-01  8.053182e-02  0.0612417187
## x30MCx1590  0.2581451284  2.291134e-01 -4.428663e-01  0.0319221025
## x30MCx1594 -0.2399803700  7.052103e-02 -2.537869e-02 -0.1661053498
## x30MCx1607 -0.2273208619  5.850737e-02 -8.854834e-02 -0.1500188641
## x30MCx1644 -0.1247688085  9.862773e-02  1.244887e-01 -0.0815171457
## x30MCx1674 -0.3052020791 -1.854778e-01 -2.720105e-01  0.1511564626
## x30MCx1682  0.3370763554 -3.667690e-01 -4.296859e-02 -0.0992829141
## x30MCx1683 -0.1309874160  4.943738e-03  1.552002e-01  0.1230751204
## x30MCx1686 -0.2618578158 -5.479892e-02  3.931175e-02  0.0506057293
## x30MCx1688 -0.3188740392 -1.762923e-01 -2.524509e-01  0.1456675566
## x30MCx1691  0.0367412496 -1.004027e-01  1.694960e-01 -0.0086506511
## x30MCx1696 -0.3092059732 -5.575687e-02 -8.714301e-02 -0.0787146781
## x30MCx1701  0.2297136850  2.576233e-01 -3.441665e-01 -0.0570938405
## x30MCx1707  0.0929880650  9.799410e-02  1.365948e-01  0.1411234267
## x30MCx1741  0.0097896982 -1.934415e-01  7.040665e-02 -0.1132074856
## x30MCx1754  0.0429321579  1.286890e-01  1.437294e-01  0.0503473830
## x30MCx1761  0.0020758635  1.918629e-01  6.260461e-02 -0.0120845339
## x30MCx1762 -0.1829631984 -2.038227e-01 -2.642879e-01  0.1671687615
## x30MCx1765 -0.0665234914 -7.957277e-03  5.409880e-02  0.2337802059
## x30MCx1767 -0.0595425480 -9.839598e-05  1.210803e-01  0.1988247150
## x30MCx1779 -0.1204572759  1.344104e-01  3.348822e-02 -0.0978205521
## x30MCx1796 -0.1481406391  2.453466e-02  4.246110e-02 -0.0356891066
## x30MCx1813  0.3094227794 -3.472863e-01  1.443496e-02 -0.1645999790
## x30MCx1832 -0.2128589495  2.666993e-02  9.680041e-02 -0.0400919020
## x30MCx1838 -0.0157924087  1.285821e-01  1.059186e-01 -0.0819914003
## x30MCx1840 -0.1753309723 -1.477401e-01 -4.995863e-02  0.2677144691
## x30MCx1851  0.1879116538  2.783503e-01 -7.259241e-03  0.0295677554
## x30MCx1852 -0.0614798924  3.639676e-02 -1.013526e-02  0.1718255271
## x30MCx1856 -0.2426853726 -1.646668e-01 -2.363359e-01  0.2406681332
## x30MCx1885 -0.2433889011 -1.819802e-01 -3.215645e-01  0.2220387485
## x30MCx1902 -0.0328410251 -6.959647e-02  1.099687e-02  0.1608245560
## x30MCx1919  0.1672098408  1.155842e-01  1.233406e-02  0.0394135031
## x30MCx1924  0.2030390409  2.453860e-01 -3.652638e-01 -0.0376039707
## x30MCx1930  0.0310411539  4.562728e-02  9.122924e-02  0.1342313481
## x30MCx1935  0.2796170981 -1.206534e-02  4.903465e-02 -0.0443735431
## x30MCx1938  0.2194516283  1.526270e-01 -4.789819e-01  0.0680335173
## x30MCx1942 -0.2414970071 -6.948016e-02  6.564492e-02  0.0766643241
## x30MCx1956  0.4379863570 -2.424941e-01 -1.725043e-01 -0.1423429577
## x30MCx1957 -0.0872395300 -3.563461e-01 -1.238209e-01  0.1114783704
## x30MCx1969  0.0641789546  1.139910e-01  7.319563e-02  0.1389511487
## x30MCx1975  0.2071862137  1.963001e-02  7.870857e-02  0.1186404095
## x30MCx1976 -0.1092811749 -3.605114e-01 -4.233677e-02  0.0057605221
## x30MCx1987 -0.0363737670 -3.586915e-01 -3.782237e-02  0.1031169180
## x30MCx1990  0.2565124113  7.289704e-02  1.825218e-02  0.1183918779
## x30MCx2004 -0.2197524487  2.949682e-02 -2.085692e-01 -0.0870652931
## x30MCx2020  0.1723314844 -2.671824e-01  1.488500e-01  0.0532686970
## x30MCx2023  0.1795662751 -3.151729e-01  8.995473e-02 -0.1497645300
## x30MCx2052 -0.1359184834 -1.368797e-01 -8.004379e-02  0.2906036223
## x30MCx2065 -0.1182054226  3.260099e-02  1.592997e-01 -0.0060687278
## x30MCx2075 -0.1623928479  3.665705e-02  1.115044e-01  0.0137531085
## x30MCx2080 -0.0638748446  1.770916e-01  7.189483e-02 -0.0458893499
## x30MCx2082 -0.3046128326 -1.535451e-01 -2.280910e-01  0.1100973087
## x30MCx2089 -0.1853951383  1.017640e-01  2.926979e-03 -0.1515685361
## x30MCx2116  0.1520524281  7.242144e-02 -4.582231e-01  0.0891123309
## x30MCx2121 -0.1813301058 -4.093970e-02  6.607854e-02  0.1302850325
## x30MCx2128 -0.2653887730 -1.223147e-01 -6.712792e-02  0.1302511204
## x30MCx2137 -0.0954450998  9.627629e-02  1.542338e-01  0.0482938723
## x30MCx2154 -0.1825397865 -1.470737e-02  1.075011e-01  0.1010611010
## x30MCx2156 -0.1954606804  3.513993e-02  8.826971e-02 -0.0898797546
## x30MCx2164  0.2941976248  2.769043e-01 -2.861963e-01  0.0085495624
## x30MCx2165 -0.2262636658 -1.366959e-01 -1.570573e-01  0.2025674437
## x30MCx2180 -0.0910850291  1.550775e-01  1.032267e-01 -0.1031090466
## x30MCx2181  0.3895405534  2.101674e-02 -8.085948e-02 -0.0792324653
## x30MCx2222  0.0861975615 -1.234523e-01  6.754896e-02  0.2227309546
## x30MCx2226  0.0265994378  1.682567e-01  1.504972e-01  0.0081764618
## x30MCx2241 -0.1690987286  2.744536e-02  7.208931e-02 -0.0585518682
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## x30MCx2261  0.1050694699 -3.979354e-01  3.094498e-03  0.1927866114
## x30MCx2280  0.2201396945 -2.115009e-01  9.801074e-02  0.0877786419
## x30MCx2296 -0.0395614800  9.305787e-02  1.494698e-01  0.0324343280
## x30MCx2303  0.0232308770 -1.030572e-01  1.251515e-01 -0.0945042455
## x30MCx2308 -0.0302894265 -2.287444e-02  8.694197e-02  0.1068716249
## x30MCx2314 -0.1673694233  1.883874e-02  6.430584e-02  0.1365157452
## x30MCx2318  0.1004883979  5.432341e-02  1.210163e-01  0.0541775462
## x30MCx2364 -0.0102222089  1.032838e-01 -3.231696e-02 -0.2343800106
## x30MCx2369 -0.1192118436 -3.503903e-01 -1.830323e-01  0.0931196939
## x30MCx2394  0.1207391202  6.579359e-03  1.086374e-01 -0.0434161401
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## x30MCx2418  0.2147751542  1.646277e-01 -4.969182e-01  0.0548422038
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## x30MCx2648 -0.0537655360
## x30MCx2656  0.0314770639
## x30MCx2671 -0.0896075455
## x30MCx2684 -0.1174986524
## x30MCx2690  0.1194070330
## x30MCx2715 -0.0424895658
## x30MCx2723  0.0484475179
## x30MCx2724  0.0012817812
## x30MCx2727 -0.0686674819
## x30MCx2731  0.1853475107
## x30MCx2774  0.1669380868
## x30MCx2780  0.0459279818
## x30MCx2785 -0.0753023995
## x30MCx2788  0.0377525353
## x30MCx2792 -0.0059497815
## x30MCx2836 -0.1670247868
## x30MCx2837  0.1449125098
## x30MCx2855  0.0733061506
## x30MCx2871  0.0348144079
## x30MCx2890 -0.0809647704
## x30MCx2898  0.0039669978
## x30MCx2935  0.0395457957
## x30MCx2940 -0.1261386007
## x30MCx2944  0.1423572701
## x30MCx2953 -0.0622687850
## x30MCx2956 -0.0001031715
## x30MCx2958  0.0668875798
## x30MCx2970 -0.0491728468
## x30MCx2974  0.0609530400
## x30MCx2977 -0.2065103844
## x30MCx2982  0.1109116096
## x30MCx3003 -0.0555852719
## x30MCx3007  0.1063395072
## x30MCx3015  0.0630719018
## x30MCx3018 -0.0506053465
## x30MCx3038 -0.0589549720
## x30MCx3045  0.0874666390
## x30MCx3053  0.1706024232
## x30MCx3064 -0.0034948028
## x30MCx3066  0.0433283644
## x30MCx3087  0.0677151975
## x30MCx3120  0.0414766871
## x30MCx3131 -0.0760419595
## x30MCx3137  0.0119086942
## x30MCx3143 -0.1307880815
## x30MCx3147 -0.0451651274
## x30MCx3154 -0.0353741077
## x30MCx3155  0.0323093618
## x30MCx3161  0.0564824759
## x30MCx3186  0.0443047303
## x30MCx3187  0.0616862720
## x30MCx3203  0.1438297836
## x30MCx3208 -0.0580526983
## x30MCx3215  0.1099077431
## x30MCx3220 -0.0095676656
## x30MCx3225 -0.0062983442
## x30MCx3244 -0.0190724436
## x30MCx3249  0.0372525470
## x30MCx3256 -0.0479307198
## x30MCx3259 -0.0517269725
## x30MCx3260 -0.0711239453
## x30MCx3270  0.0300537302
## x30MCx3279  0.0838320039
## x30MCx3285 -0.1598913322
## x30MCx3297 -0.0892121655
## x30MCx3305 -0.0370813999
## x30MCx3353  0.1672815449
## x30MCx3360 -0.1504276708
## x30MCx3367 -0.0302458387
## x30MCx3372  0.1742276547
## x30MCx3382  0.0255805047
## x30MCx1731  0.0477875534
## x30MCx2868 -0.0692020055
## x30MCx3184  0.0355589449
## x10MCx1626 -0.0371310281
## x10MCx2535  0.1298799383
## x12MCx1124 -0.0383372670
## x12MCx1361 -0.0961533849
## x12MCx1413 -0.0140744378
## x12MCx1528  0.0223383412
## x12MCx1700 -0.0467601022
## x12MCx2383 -0.0604654456
## x12MCx2493 -0.0334265768
## x12MCx2938 -0.1598984085
## x12MCx2996 -0.0927256655
## x12MCx3165 -0.1293031201
## 
## $adjusted_R2
## [1] 0.07852721
## 
## $p_value
##        value 
## 1.851443e-14 
## 
## $plot

## 
## $variance_explained
##   [1]  1.321965e-01  8.813616e-02  6.113748e-02  4.023672e-02  2.273713e-02
##   [6]  2.132878e-02  1.867645e-02  1.663686e-02  1.473336e-02  1.461339e-02
##  [11]  1.351928e-02  1.196560e-02  1.171706e-02  1.098764e-02  1.065864e-02
##  [16]  9.543417e-03  9.287766e-03  8.644136e-03  8.461105e-03  8.195180e-03
##  [21]  7.982769e-03  7.630232e-03  7.142942e-03  7.062217e-03  6.938253e-03
##  [26]  6.795237e-03  6.500876e-03  6.351970e-03  6.132816e-03  5.972421e-03
##  [31]  5.908631e-03  5.641443e-03  5.552960e-03  5.437043e-03  5.282870e-03
##  [36]  5.157998e-03  5.047189e-03  4.954586e-03  4.878079e-03  4.826973e-03
##  [41]  4.750154e-03  4.575946e-03  4.436302e-03  4.427519e-03  4.315069e-03
##  [46]  4.261284e-03  4.214078e-03  4.116230e-03  4.011405e-03  3.854022e-03
##  [51]  3.827873e-03  3.743718e-03  3.660813e-03  3.574108e-03  3.445177e-03
##  [56]  3.421646e-03  3.375656e-03  3.328468e-03  3.301436e-03  3.266200e-03
##  [61]  3.213881e-03  3.166767e-03  3.147988e-03  3.058133e-03  3.053039e-03
##  [66]  2.965575e-03  2.893485e-03  2.863451e-03  2.809757e-03  2.772956e-03
##  [71]  2.734333e-03  2.704782e-03  2.650030e-03  2.625789e-03  2.577567e-03
##  [76]  2.565998e-03  2.558910e-03  2.516521e-03  2.494946e-03  2.443499e-03
##  [81]  2.400648e-03  2.358336e-03  2.343572e-03  2.303785e-03  2.279536e-03
##  [86]  2.223958e-03  2.208583e-03  2.201107e-03  2.140033e-03  2.136977e-03
##  [91]  2.106334e-03  2.090664e-03  2.059806e-03  2.012411e-03  2.001914e-03
##  [96]  1.997681e-03  1.979891e-03  1.952832e-03  1.933059e-03  1.900615e-03
## [101]  1.898450e-03  1.851584e-03  1.834445e-03  1.802991e-03  1.795810e-03
## [106]  1.778645e-03  1.746394e-03  1.741619e-03  1.697359e-03  1.679378e-03
## [111]  1.667717e-03  1.657528e-03  1.629980e-03  1.621865e-03  1.613909e-03
## [116]  1.575099e-03  1.553535e-03  1.551191e-03  1.535519e-03  1.529722e-03
## [121]  1.502222e-03  1.479440e-03  1.446811e-03  1.438577e-03  1.432123e-03
## [126]  1.426302e-03  1.410502e-03  1.394907e-03  1.376913e-03  1.363799e-03
## [131]  1.356754e-03  1.327110e-03  1.322385e-03  1.311045e-03  1.293041e-03
## [136]  1.279920e-03  1.272891e-03  1.265098e-03  1.246280e-03  1.231671e-03
## [141]  1.230840e-03  1.218364e-03  1.203151e-03  1.198727e-03  1.185065e-03
## [146]  1.171741e-03  1.153337e-03  1.150328e-03  1.139841e-03  1.129812e-03
## [151]  1.117387e-03  1.106095e-03  1.094882e-03  1.090442e-03  1.072198e-03
## [156]  1.059028e-03  1.048560e-03  1.043595e-03  1.041820e-03  1.014599e-03
## [161]  1.011372e-03  9.973776e-04  9.796268e-04  9.784258e-04  9.660402e-04
## [166]  9.623041e-04  9.560231e-04  9.369298e-04  9.348083e-04  9.176692e-04
## [171]  9.101472e-04  9.067499e-04  8.946368e-04  8.778833e-04  8.755912e-04
## [176]  8.675691e-04  8.628603e-04  8.557155e-04  8.496985e-04  8.413571e-04
## [181]  8.273414e-04  8.225075e-04  8.129290e-04  8.108122e-04  8.003584e-04
## [186]  7.935334e-04  7.892221e-04  7.862516e-04  7.732170e-04  7.554621e-04
## [191]  7.526814e-04  7.512260e-04  7.376840e-04  7.295317e-04  7.214131e-04
## [196]  7.170371e-04  7.073935e-04  7.040607e-04  6.992679e-04  6.970523e-04
## [201]  6.903251e-04  6.853024e-04  6.748133e-04  6.670108e-04  6.618078e-04
## [206]  6.601346e-04  6.524360e-04  6.432581e-04  6.390222e-04  6.306999e-04
## [211]  6.288949e-04  6.212908e-04  6.177332e-04  6.123717e-04  6.029695e-04
## [216]  5.989631e-04  5.948762e-04  5.899156e-04  5.839800e-04  5.753201e-04
## [221]  5.653496e-04  5.593652e-04  5.533360e-04  5.490333e-04  5.446895e-04
## [226]  5.382216e-04  5.354504e-04  5.304950e-04  5.237551e-04  5.137594e-04
## [231]  5.099604e-04  5.069670e-04  4.992951e-04  4.951866e-04  4.896063e-04
## [236]  4.862873e-04  4.805573e-04  4.729800e-04  4.713345e-04  4.637411e-04
## [241]  4.601585e-04  4.559798e-04  4.549940e-04  4.465898e-04  4.459305e-04
## [246]  4.400817e-04  4.320107e-04  4.293644e-04  4.242736e-04  4.180724e-04
## [251]  4.156125e-04  4.111864e-04  4.047567e-04  3.971917e-04  3.958416e-04
## [256]  3.892062e-04  3.872620e-04  3.832575e-04  3.814245e-04  3.729708e-04
## [261]  3.695801e-04  3.691102e-04  3.621852e-04  3.582843e-04  3.541089e-04
## [266]  3.508817e-04  3.490589e-04  3.456575e-04  3.358275e-04  3.324323e-04
## [271]  3.311500e-04  3.240461e-04  3.219192e-04  3.163176e-04  3.135835e-04
## [276]  3.083125e-04  3.078135e-04  3.011824e-04  2.985832e-04  2.916584e-04
## [281]  2.908776e-04  2.882846e-04  2.846364e-04  2.834578e-04  2.763705e-04
## [286]  2.736010e-04  2.728225e-04  2.677675e-04  2.660136e-04  2.625732e-04
## [291]  2.609340e-04  2.537404e-04  2.515904e-04  2.466792e-04  2.426708e-04
## [296]  2.414786e-04  2.385803e-04  2.344453e-04  2.295707e-04  2.244026e-04
## [301]  2.225763e-04  2.193765e-04  2.181698e-04  2.141082e-04  2.064542e-04
## [306]  2.051179e-04  2.034427e-04  2.011325e-04  1.943605e-04  1.922833e-04
## [311]  1.907898e-04  1.862768e-04  1.842693e-04  1.828269e-04  1.816172e-04
## [316]  1.788836e-04  1.775632e-04  1.692199e-04  1.650392e-04  1.611354e-04
## [321]  1.598116e-04  1.551291e-04  1.524234e-04  1.500581e-04  1.492358e-04
## [326]  1.459632e-04  1.439352e-04  1.413365e-04  1.402417e-04  1.385193e-04
## [331]  1.362101e-04  1.321107e-04  1.297837e-04  1.257924e-04  1.220972e-04
## [336]  1.157167e-04  1.150212e-04  1.136216e-04  1.092252e-04  1.086510e-04
## [341]  1.041576e-04  1.031487e-04  1.004181e-04  9.915255e-05  9.463331e-05
## [346]  9.385460e-05  9.060057e-05  8.880367e-05  8.500908e-05  8.184838e-05
## [351]  7.934085e-05  7.698463e-05  7.660906e-05  7.370270e-05  7.120320e-05
## [356]  7.051059e-05  6.806327e-05  6.318750e-05  6.304532e-05  5.979700e-05
## [361]  5.883960e-05  5.439668e-05  5.129047e-05  4.825265e-05  4.577139e-05
## [366]  4.485745e-05  4.415108e-05  4.180612e-05  3.900137e-05  3.640518e-05
## [371]  3.393846e-05  3.305081e-05  2.958927e-05  2.792511e-05  2.518585e-05
## [376]  2.359037e-05  2.190924e-05  1.916952e-05  1.693485e-05  1.576421e-05
## [381]  1.217259e-05  1.103577e-05  1.043892e-05  8.255646e-06  6.786992e-06
## [386]  5.656062e-06  2.890435e-06 -1.895747e-17 -1.631530e-06 -2.698003e-06
## [391] -5.367278e-06 -6.558106e-06 -8.208650e-06 -1.113317e-05 -1.242768e-05
## [396] -1.496950e-05 -1.674167e-05 -1.821085e-05 -2.112135e-05 -2.237169e-05
## [401] -2.550164e-05 -2.604882e-05 -2.819843e-05 -2.958876e-05 -3.297564e-05
## [406] -3.310081e-05 -3.645346e-05 -3.680929e-05 -3.835691e-05 -3.995268e-05
## [411] -4.193345e-05 -4.244099e-05 -4.539077e-05 -4.709509e-05 -4.844032e-05
## [416] -4.985549e-05 -5.055078e-05 -5.230333e-05 -5.566792e-05 -5.799698e-05
## [421] -5.877753e-05 -5.975121e-05 -6.222894e-05 -6.263519e-05 -6.568478e-05
## [426] -6.698696e-05 -6.751757e-05 -6.905154e-05 -7.224862e-05 -7.253124e-05
## [431] -7.468365e-05 -7.994356e-05 -8.059251e-05 -8.095538e-05 -8.289780e-05
## [436] -8.479747e-05 -8.626371e-05 -8.717211e-05 -8.876087e-05 -9.082463e-05
## [441] -9.367032e-05 -9.456986e-05 -9.533407e-05 -9.591518e-05 -9.730589e-05
## [446] -9.873759e-05 -1.003161e-04 -1.013072e-04 -1.037164e-04 -1.042845e-04
## [451] -1.050061e-04 -1.084917e-04 -1.087846e-04 -1.116531e-04 -1.136708e-04
## [456] -1.146555e-04 -1.158768e-04 -1.172206e-04 -1.196076e-04 -1.206403e-04
## [461] -1.227686e-04 -1.237460e-04 -1.246169e-04 -1.266192e-04 -1.289189e-04
## [466] -1.296581e-04 -1.306940e-04 -1.323516e-04 -1.332737e-04 -1.352449e-04
## [471] -1.363460e-04 -1.381277e-04 -1.407106e-04 -1.409302e-04 -1.425218e-04
## [476] -1.442682e-04 -1.454495e-04 -1.462143e-04 -1.478914e-04 -1.482068e-04
## [481] -1.511231e-04 -1.515686e-04 -1.528271e-04 -1.541953e-04 -1.557581e-04
## [486] -1.562516e-04 -1.577404e-04 -1.592854e-04 -1.602950e-04 -1.615789e-04
## [491] -1.630688e-04 -1.638408e-04 -1.649205e-04 -1.674168e-04 -1.684231e-04
## [496] -1.707443e-04 -1.710488e-04 -1.716554e-04 -1.721186e-04 -1.734741e-04
## [501] -1.762659e-04 -1.777016e-04 -1.790063e-04 -1.799069e-04 -1.803123e-04
## [506] -1.816863e-04 -1.827116e-04 -1.844524e-04 -1.846953e-04 -1.854015e-04
## [511] -1.881907e-04 -1.896574e-04 -1.900824e-04 -1.916728e-04 -1.944083e-04
## [516] -1.949122e-04 -1.965368e-04 -1.968113e-04 -1.981438e-04 -1.990597e-04
## [521] -2.003491e-04 -2.013960e-04 -2.026543e-04 -2.040667e-04 -2.052213e-04
## [526] -2.058829e-04 -2.076043e-04 -2.094405e-04 -2.099099e-04 -2.109868e-04
## [531] -2.119886e-04 -2.130074e-04 -2.135009e-04 -2.139339e-04 -2.167371e-04
## [536] -2.175045e-04 -2.197037e-04 -2.207199e-04 -2.219240e-04 -2.230949e-04
## [541] -2.238079e-04 -2.247593e-04 -2.266921e-04 -2.272276e-04 -2.281222e-04
## [546] -2.290777e-04 -2.295168e-04 -2.301558e-04 -2.321406e-04 -2.323981e-04
## [551] -2.341524e-04 -2.351094e-04 -2.353817e-04 -2.371572e-04 -2.382613e-04
## [556] -2.403152e-04 -2.408468e-04 -2.416367e-04 -2.433718e-04 -2.438403e-04
## [561] -2.451231e-04 -2.461111e-04 -2.463460e-04 -2.478781e-04 -2.505431e-04
## [566] -2.511137e-04 -2.522682e-04 -2.539177e-04 -2.546700e-04 -2.548984e-04
## [571] -2.557894e-04 -2.575775e-04 -2.585969e-04 -2.589689e-04 -2.599848e-04
## [576] -2.607810e-04 -2.618042e-04 -2.626226e-04 -2.637931e-04 -2.643333e-04
## [581] -2.654113e-04 -2.673701e-04 -2.680577e-04 -2.692778e-04 -2.707113e-04
## [586] -2.720629e-04 -2.725469e-04 -2.742799e-04 -2.750079e-04 -2.757007e-04
## [591] -2.765308e-04 -2.781729e-04 -2.786543e-04 -2.796918e-04 -2.799732e-04
## [596] -2.811393e-04 -2.829441e-04 -2.830745e-04 -2.848406e-04 -2.862232e-04
## [601] -2.870422e-04 -2.877426e-04 -2.894705e-04 -2.907088e-04 -2.911371e-04
## [606] -2.917902e-04 -2.931926e-04 -2.952735e-04 -2.967793e-04 -2.970417e-04
## [611] -2.985021e-04 -3.000341e-04 -3.009631e-04 -3.025233e-04 -3.035769e-04
## [616] -3.045246e-04 -3.066445e-04 -3.074491e-04 -3.083577e-04 -3.090332e-04
## [621] -3.099572e-04 -3.113213e-04 -3.128029e-04 -3.133564e-04 -3.137491e-04
## [626] -3.144807e-04 -3.164245e-04 -3.173701e-04 -3.187414e-04 -3.191383e-04
## [631] -3.204002e-04 -3.210153e-04 -3.211829e-04 -3.225995e-04 -3.233417e-04
## [636] -3.237796e-04 -3.248376e-04 -3.272238e-04 -3.279927e-04 -3.295955e-04
## [641] -3.306247e-04 -3.312371e-04 -3.324373e-04 -3.336721e-04 -3.344987e-04
## [646] -3.345337e-04 -3.368018e-04 -3.379376e-04 -3.393209e-04 -3.409712e-04
## [651] -3.411956e-04 -3.423001e-04 -3.433383e-04 -3.438440e-04 -3.447297e-04
## [656] -3.461577e-04 -3.470559e-04 -3.486206e-04 -3.497737e-04 -3.510255e-04
## [661] -3.523206e-04 -3.534393e-04 -3.542642e-04 -3.559241e-04 -3.569533e-04
## [666] -3.579719e-04 -3.589241e-04 -3.602310e-04 -3.610069e-04 -3.624682e-04
## [671] -3.640150e-04 -3.651900e-04 -3.659113e-04 -3.666262e-04 -3.679363e-04
## [676] -3.693133e-04 -3.697813e-04 -3.712046e-04 -3.730621e-04 -3.736474e-04
## [681] -3.743913e-04 -3.747422e-04 -3.756425e-04 -3.764152e-04 -3.775132e-04
## [686] -3.790942e-04 -3.803391e-04 -3.820087e-04 -3.829160e-04 -3.850504e-04
## [691] -3.865201e-04 -3.876292e-04 -3.887142e-04 -3.892963e-04 -3.909772e-04
## [696] -3.922419e-04 -3.931780e-04 -3.945771e-04 -3.953694e-04 -3.963977e-04
## [701] -3.977306e-04 -3.981692e-04 -4.003162e-04 -4.012423e-04 -4.023341e-04
## [706] -4.044872e-04 -4.045288e-04 -4.076214e-04 -4.095096e-04 -4.102950e-04
## [711] -4.106450e-04 -4.118394e-04 -4.126639e-04 -4.151470e-04 -4.154429e-04
## [716] -4.175444e-04 -4.200065e-04 -4.203171e-04 -4.206969e-04 -4.227718e-04
## [721] -4.240489e-04 -4.247682e-04 -4.262131e-04 -4.283284e-04 -4.292282e-04
## [726] -4.299209e-04 -4.322870e-04 -4.332123e-04 -4.351450e-04 -4.356776e-04
## [731] -4.383075e-04 -4.398749e-04 -4.420500e-04 -4.430337e-04 -4.436407e-04
## [736] -4.443179e-04 -4.452525e-04 -4.469027e-04 -4.480248e-04 -4.500539e-04
## [741] -4.520372e-04 -4.544276e-04 -4.563353e-04 -4.584581e-04 -4.591026e-04
## [746] -4.614888e-04 -4.618928e-04 -4.649216e-04 -4.652654e-04 -4.663438e-04
## [751] -4.682190e-04 -4.696349e-04 -4.714572e-04 -4.724280e-04 -4.737744e-04
## [756] -4.748546e-04 -4.783315e-04 -4.801626e-04 -4.814466e-04 -4.838890e-04
## [761] -4.857766e-04 -4.875855e-04 -4.887611e-04 -4.891858e-04 -4.932153e-04
## [766] -4.943050e-04 -4.955932e-04 -4.974398e-04 -4.987693e-04 -5.021989e-04
## [771] -5.024950e-04 -5.067892e-04 -5.078030e-04 -5.092537e-04 -5.118832e-04
## [776] -5.153512e-04 -5.161128e-04 -5.188763e-04 -5.206057e-04 -5.232743e-04
## [781] -5.263979e-04 -5.284897e-04 -5.303308e-04 -5.310109e-04 -5.346192e-04
## [786] -5.351727e-04 -5.371530e-04 -5.418124e-04 -5.433312e-04 -5.482170e-04
## [791] -5.491898e-04 -5.510934e-04 -5.577702e-04 -5.641503e-04 -5.666983e-04
## [796] -5.690994e-04 -5.703175e-04 -5.740665e-04 -5.755355e-04 -5.816905e-04
## [801] -5.835009e-04 -5.879934e-04 -5.899507e-04 -5.923599e-04 -5.936118e-04
## [806] -5.980073e-04 -6.099152e-04 -6.116667e-04 -6.148531e-04 -6.175785e-04
## [811] -6.288230e-04 -6.320455e-04 -6.333484e-04 -6.384644e-04 -6.492775e-04
## [816] -6.544907e-04 -6.586099e-04 -6.658796e-04 -6.709068e-04 -6.767169e-04
## [821] -6.812427e-04 -6.887386e-04 -7.000902e-04 -7.189182e-04 -7.235192e-04
## [826] -7.347816e-04 -7.448612e-04 -7.516936e-04 -7.659763e-04 -7.905161e-04
## [831] -7.961765e-04 -8.274285e-04 -8.430855e-04 -8.474885e-04 -8.604555e-04
## [836] -8.845030e-04 -9.110551e-04 -9.321458e-04 -9.840447e-04 -1.051364e-03
## [841] -1.135217e-03 -1.437984e-03 -2.289291e-03
evaluate_consistency_metrics(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
## $trustworthiness
## [1] 0.6398316
## 
## $continuity
## [1] 0.8387269
## 
## $mantel_statistic
## [1] 0.3321321
## 
## $mantel_p
## [1] 0.001
cjtt_u_test(dist_bray_filt, HbA1c_filt, var_method = "analytic")
## $U_statistic
## [1] 0.09906087
## 
## $variance
## [1] 0.0005265915
## 
## $z_score
## [1] 4.316833
## 
## $p_value
## [1] 1.582839e-05
## 
## $method
## [1] "analytic"
gco_decomposition(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
##     consistency_score outlier        class
## 1                 0.1   FALSE       C-type
## 2                 0.0   FALSE       C-type
## 3                 0.0   FALSE       C-type
## 4                 0.0   FALSE       C-type
## 5                 0.2   FALSE Intermediate
## 6                 0.2   FALSE Intermediate
## 7                 0.0   FALSE       C-type
## 8                 0.1   FALSE       C-type
## 9                 0.1   FALSE       C-type
## 10                0.0   FALSE       C-type
## 11                0.1   FALSE       C-type
## 12                0.0   FALSE       C-type
## 13                0.1   FALSE       C-type
## 14                0.2   FALSE Intermediate
## 15                0.1   FALSE       C-type
## 16                0.0   FALSE       C-type
## 17                0.3    TRUE       O-type
## 18                0.0   FALSE       C-type
## 19                0.0   FALSE       C-type
## 20                0.2    TRUE       O-type
## 21                0.1   FALSE       C-type
## 22                0.0   FALSE       C-type
## 23                0.0   FALSE       C-type
## 24                0.5    TRUE       O-type
## 25                0.0   FALSE       C-type
## 26                0.0   FALSE       C-type
## 27                0.2   FALSE Intermediate
## 28                0.1   FALSE       C-type
## 29                0.0   FALSE       C-type
## 30                0.1   FALSE       C-type
## 31                0.0   FALSE       C-type
## 32                0.0   FALSE       C-type
## 33                0.0   FALSE       C-type
## 34                0.1   FALSE       C-type
## 35                0.1   FALSE       C-type
## 36                0.0   FALSE       C-type
## 37                0.0   FALSE       C-type
## 38                0.1   FALSE       C-type
## 39                0.2    TRUE       O-type
## 40                0.0   FALSE       C-type
## 41                0.0   FALSE       C-type
## 42                0.0   FALSE       C-type
## 43                0.1   FALSE       C-type
## 44                0.1   FALSE       C-type
## 45                0.1   FALSE       C-type
## 46                0.2   FALSE Intermediate
## 47                0.1   FALSE       C-type
## 48                0.0   FALSE       C-type
## 49                0.1   FALSE       C-type
## 50                0.0   FALSE       C-type
## 51                0.2   FALSE Intermediate
## 52                0.2   FALSE Intermediate
## 53                0.1   FALSE       C-type
## 54                0.0   FALSE       C-type
## 55                0.0   FALSE       C-type
## 56                0.0   FALSE       C-type
## 57                0.0   FALSE       C-type
## 58                0.0   FALSE       C-type
## 59                0.1   FALSE       C-type
## 60                0.2   FALSE Intermediate
## 61                0.0   FALSE       C-type
## 62                0.0   FALSE       C-type
## 63                0.0   FALSE       C-type
## 64                0.1   FALSE       C-type
## 65                0.2   FALSE Intermediate
## 66                0.0   FALSE       C-type
## 67                0.2   FALSE Intermediate
## 68                0.0   FALSE       C-type
## 69                0.2   FALSE Intermediate
## 70                0.0   FALSE       C-type
## 71                0.1   FALSE       C-type
## 72                0.0   FALSE       C-type
## 73                0.1   FALSE       C-type
## 74                0.0   FALSE       C-type
## 75                0.0   FALSE       C-type
## 76                0.1   FALSE       C-type
## 77                0.2   FALSE Intermediate
## 78                0.0   FALSE       C-type
## 79                0.0    TRUE       O-type
## 80                0.1   FALSE       C-type
## 81                0.0   FALSE       C-type
## 82                0.0   FALSE       C-type
## 83                0.0   FALSE       C-type
## 84                0.0   FALSE       C-type
## 85                0.0    TRUE       O-type
## 86                0.1   FALSE       C-type
## 87                0.1   FALSE       C-type
## 88                0.0   FALSE       C-type
## 89                0.1   FALSE       C-type
## 90                0.0   FALSE       C-type
## 91                0.0   FALSE       C-type
## 92                0.2   FALSE Intermediate
## 93                0.0   FALSE       C-type
## 94                0.1   FALSE       C-type
## 95                0.1   FALSE       C-type
## 96                0.2   FALSE Intermediate
## 97                0.0   FALSE       C-type
## 98                0.0   FALSE       C-type
## 99                0.0   FALSE       C-type
## 100               0.0   FALSE       C-type
## 101               0.0   FALSE       C-type
## 102               0.1   FALSE       C-type
## 103               0.0   FALSE       C-type
## 104               0.0   FALSE       C-type
## 105               0.0   FALSE       C-type
## 106               0.0   FALSE       C-type
## 107               0.0   FALSE       C-type
## 108               0.1   FALSE       C-type
## 109               0.0   FALSE       C-type
## 110               0.1   FALSE       C-type
## 111               0.0   FALSE       C-type
## 112               0.0   FALSE       C-type
## 113               0.0   FALSE       C-type
## 114               0.0   FALSE       C-type
## 115               0.0   FALSE       C-type
## 116               0.0   FALSE       C-type
## 117               0.0   FALSE       C-type
## 118               0.0   FALSE       C-type
## 119               0.0   FALSE       C-type
## 120               0.0   FALSE       C-type
## 121               0.0   FALSE       C-type
## 122               0.0   FALSE       C-type
## 123               0.0    TRUE       O-type
## 124               0.1   FALSE       C-type
## 125               0.0   FALSE       C-type
## 126               0.0   FALSE       C-type
## 127               0.2   FALSE Intermediate
## 128               0.0   FALSE       C-type
## 129               0.0    TRUE       O-type
## 130               0.1   FALSE       C-type
## 131               0.0   FALSE       C-type
## 132               0.2   FALSE Intermediate
## 133               0.0   FALSE       C-type
## 134               0.1   FALSE       C-type
## 135               0.0   FALSE       C-type
## 136               0.0   FALSE       C-type
## 137               0.1   FALSE       C-type
## 138               0.1   FALSE       C-type
## 139               0.0   FALSE       C-type
## 140               0.1   FALSE       C-type
## 141               0.1   FALSE       C-type
## 142               0.0   FALSE       C-type
## 143               0.1   FALSE       C-type
## 144               0.0   FALSE       C-type
## 145               0.0   FALSE       C-type
## 146               0.1   FALSE       C-type
## 147               0.0   FALSE       C-type
## 148               0.0   FALSE       C-type
## 149               0.1   FALSE       C-type
## 150               0.0   FALSE       C-type
## 151               0.0   FALSE       C-type
## 152               0.1   FALSE       C-type
## 153               0.0   FALSE       C-type
## 154               0.2   FALSE Intermediate
## 155               0.1   FALSE       C-type
## 156               0.0   FALSE       C-type
## 157               0.0   FALSE       C-type
## 158               0.0   FALSE       C-type
## 159               0.1   FALSE       C-type
## 160               0.1   FALSE       C-type
## 161               0.2   FALSE Intermediate
## 162               0.0   FALSE       C-type
## 163               0.1   FALSE       C-type
## 164               0.0   FALSE       C-type
## 165               0.0   FALSE       C-type
## 166               0.0   FALSE       C-type
## 167               0.0   FALSE       C-type
## 168               0.1   FALSE       C-type
## 169               0.1    TRUE       O-type
## 170               0.1   FALSE       C-type
## 171               0.0   FALSE       C-type
## 172               0.1   FALSE       C-type
## 173               0.1   FALSE       C-type
## 174               0.0   FALSE       C-type
## 175               0.0   FALSE       C-type
## 176               0.1    TRUE       O-type
## 177               0.0   FALSE       C-type
## 178               0.0   FALSE       C-type
## 179               0.0   FALSE       C-type
## 180               0.0   FALSE       C-type
## 181               0.0   FALSE       C-type
## 182               0.0   FALSE       C-type
## 183               0.1   FALSE       C-type
## 184               0.0   FALSE       C-type
## 185               0.2   FALSE Intermediate
## 186               0.1   FALSE       C-type
## 187               0.0   FALSE       C-type
## 188               0.6    TRUE       O-type
## 189               0.0   FALSE       C-type
## 190               0.0   FALSE       C-type
## 191               0.0   FALSE       C-type
## 192               0.2   FALSE Intermediate
## 193               0.0   FALSE       C-type
## 194               0.0   FALSE       C-type
## 195               0.0   FALSE       C-type
## 196               0.1   FALSE       C-type
## 197               0.0   FALSE       C-type
## 198               0.1   FALSE       C-type
## 199               0.0   FALSE       C-type
## 200               0.0   FALSE       C-type
## 201               0.0   FALSE       C-type
## 202               0.0   FALSE       C-type
## 203               0.0   FALSE       C-type
## 204               0.1   FALSE       C-type
## 205               0.1   FALSE       C-type
## 206               0.1   FALSE       C-type
## 207               0.0   FALSE       C-type
## 208               0.1   FALSE       C-type
## 209               0.2    TRUE       O-type
## 210               0.0   FALSE       C-type
## 211               0.1   FALSE       C-type
## 212               0.1   FALSE       C-type
## 213               0.1   FALSE       C-type
## 214               0.0   FALSE       C-type
## 215               0.0   FALSE       C-type
## 216               0.1   FALSE       C-type
## 217               0.0   FALSE       C-type
## 218               0.1   FALSE       C-type
## 219               0.0   FALSE       C-type
## 220               0.0   FALSE       C-type
## 221               0.0    TRUE       O-type
## 222               0.0   FALSE       C-type
## 223               0.1    TRUE       O-type
## 224               0.0   FALSE       C-type
## 225               0.0   FALSE       C-type
## 226               0.1   FALSE       C-type
## 227               0.1   FALSE       C-type
## 228               0.1   FALSE       C-type
## 229               0.0   FALSE       C-type
## 230               0.0   FALSE       C-type
## 231               0.0   FALSE       C-type
## 232               0.0   FALSE       C-type
## 233               0.1   FALSE       C-type
## 234               0.1   FALSE       C-type
## 235               0.1   FALSE       C-type
## 236               0.1   FALSE       C-type
## 237               0.0   FALSE       C-type
## 238               0.1   FALSE       C-type
## 239               0.1   FALSE       C-type
## 240               0.0   FALSE       C-type
## 241               0.0   FALSE       C-type
## 242               0.0   FALSE       C-type
## 243               0.0   FALSE       C-type
## 244               0.1   FALSE       C-type
## 245               0.1   FALSE       C-type
## 246               0.0    TRUE       O-type
## 247               0.0   FALSE       C-type
## 248               0.1   FALSE       C-type
## 249               0.0   FALSE       C-type
## 250               0.2   FALSE Intermediate
## 251               0.0   FALSE       C-type
## 252               0.0   FALSE       C-type
## 253               0.0   FALSE       C-type
## 254               0.1   FALSE       C-type
## 255               0.2   FALSE Intermediate
## 256               0.2   FALSE Intermediate
## 257               0.2   FALSE Intermediate
## 258               0.0   FALSE       C-type
## 259               0.0   FALSE       C-type
## 260               0.1   FALSE       C-type
## 261               0.1   FALSE       C-type
## 262               0.0   FALSE       C-type
## 263               0.0   FALSE       C-type
## 264               0.1   FALSE       C-type
## 265               0.0   FALSE       C-type
## 266               0.0   FALSE       C-type
## 267               0.1   FALSE       C-type
## 268               0.0   FALSE       C-type
## 269               0.1   FALSE       C-type
## 270               0.0   FALSE       C-type
## 271               0.0   FALSE       C-type
## 272               0.0   FALSE       C-type
## 273               0.1   FALSE       C-type
## 274               0.0   FALSE       C-type
## 275               0.1   FALSE       C-type
## 276               0.1   FALSE       C-type
## 277               0.0   FALSE       C-type
## 278               0.0   FALSE       C-type
## 279               0.0   FALSE       C-type
## 280               0.0   FALSE       C-type
## 281               0.0   FALSE       C-type
## 282               0.0   FALSE       C-type
## 283               0.0   FALSE       C-type
## 284               0.0   FALSE       C-type
## 285               0.0   FALSE       C-type
## 286               0.0   FALSE       C-type
## 287               0.1   FALSE       C-type
## 288               0.1   FALSE       C-type
## 289               0.1   FALSE       C-type
## 290               0.1   FALSE       C-type
## 291               0.0   FALSE       C-type
## 292               0.2    TRUE       O-type
## 293               0.0   FALSE       C-type
## 294               0.0   FALSE       C-type
## 295               0.0   FALSE       C-type
## 296               0.1   FALSE       C-type
## 297               0.1   FALSE       C-type
## 298               0.0   FALSE       C-type
## 299               0.2   FALSE Intermediate
## 300               0.2   FALSE Intermediate
## 301               0.0   FALSE       C-type
## 302               0.0   FALSE       C-type
## 303               0.0   FALSE       C-type
## 304               0.1   FALSE       C-type
## 305               0.1   FALSE       C-type
## 306               0.0   FALSE       C-type
## 307               0.0   FALSE       C-type
## 308               0.0   FALSE       C-type
## 309               0.0   FALSE       C-type
## 310               0.0   FALSE       C-type
## 311               0.0   FALSE       C-type
## 312               0.2   FALSE Intermediate
## 313               0.0   FALSE       C-type
## 314               0.1   FALSE       C-type
## 315               0.0   FALSE       C-type
## 316               0.1   FALSE       C-type
## 317               0.0   FALSE       C-type
## 318               0.1   FALSE       C-type
## 319               0.1   FALSE       C-type
## 320               0.0   FALSE       C-type
## 321               0.0   FALSE       C-type
## 322               0.0   FALSE       C-type
## 323               0.0   FALSE       C-type
## 324               0.2    TRUE       O-type
## 325               0.0   FALSE       C-type
## 326               0.1   FALSE       C-type
## 327               0.0   FALSE       C-type
## 328               0.1   FALSE       C-type
## 329               0.0   FALSE       C-type
## 330               0.0   FALSE       C-type
## 331               0.0   FALSE       C-type
## 332               0.0   FALSE       C-type
## 333               0.1   FALSE       C-type
## 334               0.0   FALSE       C-type
## 335               0.0   FALSE       C-type
## 336               0.1   FALSE       C-type
## 337               0.2   FALSE Intermediate
## 338               0.0   FALSE       C-type
## 339               0.0   FALSE       C-type
## 340               0.0   FALSE       C-type
## 341               0.1   FALSE       C-type
## 342               0.0   FALSE       C-type
## 343               0.0   FALSE       C-type
## 344               0.0   FALSE       C-type
## 345               0.1   FALSE       C-type
## 346               0.2    TRUE       O-type
## 347               0.2   FALSE Intermediate
## 348               0.0   FALSE       C-type
## 349               0.0   FALSE       C-type
## 350               0.0   FALSE       C-type
## 351               0.0   FALSE       C-type
## 352               0.1   FALSE       C-type
## 353               0.1   FALSE       C-type
## 354               0.0   FALSE       C-type
## 355               0.0   FALSE       C-type
## 356               0.1   FALSE       C-type
## 357               0.1    TRUE       O-type
## 358               0.2    TRUE       O-type
## 359               0.0   FALSE       C-type
## 360               0.1   FALSE       C-type
## 361               0.0   FALSE       C-type
## 362               0.1   FALSE       C-type
## 363               0.0   FALSE       C-type
## 364               0.2    TRUE       O-type
## 365               0.1   FALSE       C-type
## 366               0.0   FALSE       C-type
## 367               0.1   FALSE       C-type
## 368               0.0   FALSE       C-type
## 369               0.0   FALSE       C-type
## 370               0.0   FALSE       C-type
## 371               0.1   FALSE       C-type
## 372               0.0   FALSE       C-type
## 373               0.0   FALSE       C-type
## 374               0.0   FALSE       C-type
## 375               0.0   FALSE       C-type
## 376               0.0   FALSE       C-type
## 377               0.1   FALSE       C-type
## 378               0.0   FALSE       C-type
## 379               0.0   FALSE       C-type
## 380               0.0   FALSE       C-type
## 381               0.0   FALSE       C-type
## 382               0.2    TRUE       O-type
## 383               0.1   FALSE       C-type
## 384               0.0    TRUE       O-type
## 385               0.2   FALSE Intermediate
## 386               0.0   FALSE       C-type
## 387               0.1    TRUE       O-type
## 388               0.0   FALSE       C-type
## 389               0.0   FALSE       C-type
## 390               0.1   FALSE       C-type
## 391               0.0   FALSE       C-type
## 392               0.1   FALSE       C-type
## 393               0.0   FALSE       C-type
## 394               0.1   FALSE       C-type
## 395               0.1   FALSE       C-type
## 396               0.2    TRUE       O-type
## 397               0.0   FALSE       C-type
## 398               0.0   FALSE       C-type
## 399               0.0   FALSE       C-type
## 400               0.1   FALSE       C-type
## 401               0.1   FALSE       C-type
## 402               0.0   FALSE       C-type
## 403               0.0   FALSE       C-type
## 404               0.0   FALSE       C-type
## 405               0.1   FALSE       C-type
## 406               0.2    TRUE       O-type
## 407               0.1   FALSE       C-type
## 408               0.1   FALSE       C-type
## 409               0.1   FALSE       C-type
## 410               0.1   FALSE       C-type
## 411               0.1   FALSE       C-type
## 412               0.1   FALSE       C-type
## 413               0.0   FALSE       C-type
## 414               0.0   FALSE       C-type
## 415               0.1   FALSE       C-type
## 416               0.0   FALSE       C-type
## 417               0.0   FALSE       C-type
## 418               0.1   FALSE       C-type
## 419               0.0   FALSE       C-type
## 420               0.2   FALSE Intermediate
## 421               0.6    TRUE       O-type
## 422               0.0   FALSE       C-type
## 423               0.0   FALSE       C-type
## 424               0.1   FALSE       C-type
## 425               0.0   FALSE       C-type
## 426               0.0   FALSE       C-type
## 427               0.0   FALSE       C-type
## 428               0.2   FALSE Intermediate
## 429               0.0   FALSE       C-type
## 430               0.0   FALSE       C-type
## 431               0.0   FALSE       C-type
## 432               0.0   FALSE       C-type
## 433               0.2   FALSE Intermediate
## 434               0.4   FALSE Intermediate
## 435               0.2   FALSE Intermediate
## 436               0.2   FALSE Intermediate
## 437               0.0   FALSE       C-type
## 438               0.0   FALSE       C-type
## 439               0.0   FALSE       C-type
## 440               0.0   FALSE       C-type
## 441               0.1    TRUE       O-type
## 442               0.0   FALSE       C-type
## 443               0.0   FALSE       C-type
## 444               0.0   FALSE       C-type
## 445               0.0   FALSE       C-type
## 446               0.1   FALSE       C-type
## 447               0.1   FALSE       C-type
## 448               0.0   FALSE       C-type
## 449               0.2   FALSE Intermediate
## 450               0.0   FALSE       C-type
## 451               0.3   FALSE Intermediate
## 452               0.1    TRUE       O-type
## 453               0.0   FALSE       C-type
## 454               0.1   FALSE       C-type
## 455               0.0   FALSE       C-type
## 456               0.0   FALSE       C-type
## 457               0.6    TRUE       O-type
## 458               0.0   FALSE       C-type
## 459               0.0   FALSE       C-type
## 460               0.0   FALSE       C-type
## 461               0.0   FALSE       C-type
## 462               0.0   FALSE       C-type
## 463               0.0   FALSE       C-type
## 464               0.0    TRUE       O-type
## 465               0.3   FALSE Intermediate
## 466               0.2   FALSE Intermediate
## 467               0.2   FALSE Intermediate
## 468               0.1   FALSE       C-type
## 469               0.3   FALSE Intermediate
## 470               0.0    TRUE       O-type
## 471               0.0   FALSE       C-type
## 472               0.1   FALSE       C-type
## 473               0.0   FALSE       C-type
## 474               0.1   FALSE       C-type
## 475               0.0    TRUE       O-type
## 476               0.1   FALSE       C-type
## 477               0.0   FALSE       C-type
## 478               0.3    TRUE       O-type
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## 480               0.0   FALSE       C-type
## 481               0.1   FALSE       C-type
## 482               0.1   FALSE       C-type
## 483               0.3   FALSE Intermediate
## 484               0.4    TRUE       O-type
## 485               0.4   FALSE Intermediate
## 486               0.1   FALSE       C-type
## 487               0.1    TRUE       O-type
## 488               0.1   FALSE       C-type
## 489               0.1   FALSE       C-type
## 490               0.0   FALSE       C-type
## 491               0.0   FALSE       C-type
## 492               0.0    TRUE       O-type
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## 494               0.1   FALSE       C-type
## 495               0.1    TRUE       O-type
## 496               0.0    TRUE       O-type
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## 500               0.0   FALSE       C-type
## 501               0.1   FALSE       C-type
## 502               0.0   FALSE       C-type
## 503               0.2   FALSE Intermediate
## 504               0.1   FALSE       C-type
## 505               0.0   FALSE       C-type
## 506               0.3   FALSE Intermediate
## 507               0.0   FALSE       C-type
## 508               0.0   FALSE       C-type
## 509               0.1   FALSE       C-type
## 510               0.1   FALSE       C-type
## 511               0.0   FALSE       C-type
## 512               0.2    TRUE       O-type
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## 515               0.0   FALSE       C-type
## 516               0.0   FALSE       C-type
## 517               0.0   FALSE       C-type
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## 519               0.1   FALSE       C-type
## 520               0.0    TRUE       O-type
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## 523               0.1   FALSE       C-type
## 524               0.0   FALSE       C-type
## 525               0.0   FALSE       C-type
## 526               0.0   FALSE       C-type
## 527               0.0   FALSE       C-type
## 528               0.0   FALSE       C-type
## 529               0.1   FALSE       C-type
## 530               0.2    TRUE       O-type
## 531               0.2   FALSE Intermediate
## 532               0.0   FALSE       C-type
## 533               0.0    TRUE       O-type
## 534               0.0   FALSE       C-type
## 535               0.0   FALSE       C-type
## 536               0.0   FALSE       C-type
## 537               0.0   FALSE       C-type
## 538               0.0   FALSE       C-type
## 539               0.1   FALSE       C-type
## 540               0.0   FALSE       C-type
## 541               0.0   FALSE       C-type
## 542               0.0   FALSE       C-type
## 543               0.0   FALSE       C-type
## 544               0.3   FALSE Intermediate
## 545               0.1   FALSE       C-type
## 546               0.0   FALSE       C-type
## 547               0.2    TRUE       O-type
## 548               0.0   FALSE       C-type
## 549               0.1   FALSE       C-type
## 550               0.0    TRUE       O-type
## 551               0.1   FALSE       C-type
## 552               0.2   FALSE Intermediate
## 553               0.0   FALSE       C-type
## 554               0.0   FALSE       C-type
## 555               0.1   FALSE       C-type
## 556               0.0   FALSE       C-type
## 557               0.1   FALSE       C-type
## 558               0.2   FALSE Intermediate
## 559               0.0   FALSE       C-type
## 560               0.0   FALSE       C-type
## 561               0.0   FALSE       C-type
## 562               0.1   FALSE       C-type
## 563               0.0   FALSE       C-type
## 564               0.0   FALSE       C-type
## 565               0.1   FALSE       C-type
## 566               0.0   FALSE       C-type
## 567               0.0   FALSE       C-type
## 568               0.0   FALSE       C-type
## 569               0.1    TRUE       O-type
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## 571               0.0   FALSE       C-type
## 572               0.0   FALSE       C-type
## 573               0.0   FALSE       C-type
## 574               0.5   FALSE Intermediate
## 575               0.0   FALSE       C-type
## 576               0.0   FALSE       C-type
## 577               0.0   FALSE       C-type
## 578               0.0   FALSE       C-type
## 579               0.0   FALSE       C-type
## 580               0.0   FALSE       C-type
## 581               0.0   FALSE       C-type
## 582               0.0   FALSE       C-type
## 583               0.0    TRUE       O-type
## 584               0.0   FALSE       C-type
## 585               0.0    TRUE       O-type
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## 588               0.0    TRUE       O-type
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## 591               0.2    TRUE       O-type
## 592               0.1   FALSE       C-type
## 593               0.0   FALSE       C-type
## 594               0.0   FALSE       C-type
## 595               0.0   FALSE       C-type
## 596               0.1   FALSE       C-type
## 597               0.1   FALSE       C-type
## 598               0.1   FALSE       C-type
## 599               0.0    TRUE       O-type
## 600               0.1    TRUE       O-type
## 601               0.0   FALSE       C-type
## 602               0.0   FALSE       C-type
## 603               0.1   FALSE       C-type
## 604               0.0   FALSE       C-type
## 605               0.0   FALSE       C-type
## 606               0.0    TRUE       O-type
## 607               0.0   FALSE       C-type
## 608               0.0   FALSE       C-type
## 609               0.1    TRUE       O-type
## 610               0.0   FALSE       C-type
## 611               0.3   FALSE Intermediate
## 612               0.0   FALSE       C-type
## 613               0.1   FALSE       C-type
## 614               0.0   FALSE       C-type
## 615               0.0   FALSE       C-type
## 616               0.0   FALSE       C-type
## 617               0.0   FALSE       C-type
## 618               0.0   FALSE       C-type
## 619               0.1   FALSE       C-type
## 620               0.0   FALSE       C-type
## 621               0.0   FALSE       C-type
## 622               0.1   FALSE       C-type
## 623               0.0    TRUE       O-type
## 624               0.0   FALSE       C-type
## 625               0.0   FALSE       C-type
## 626               0.0   FALSE       C-type
## 627               0.1   FALSE       C-type
## 628               0.0   FALSE       C-type
## 629               0.1   FALSE       C-type
## 630               0.0   FALSE       C-type
## 631               0.1   FALSE       C-type
## 632               0.0   FALSE       C-type
## 633               0.0   FALSE       C-type
## 634               0.0   FALSE       C-type
## 635               0.0   FALSE       C-type
## 636               0.0   FALSE       C-type
## 637               0.0   FALSE       C-type
## 638               0.0   FALSE       C-type
## 639               0.0   FALSE       C-type
## 640               0.3    TRUE       O-type
## 641               0.0   FALSE       C-type
## 642               0.4   FALSE Intermediate
## 643               0.0   FALSE       C-type
## 644               0.0   FALSE       C-type
## 645               0.0   FALSE       C-type
## 646               0.1   FALSE       C-type
## 647               0.1   FALSE       C-type
## 648               0.0   FALSE       C-type
## 649               0.1   FALSE       C-type
## 650               0.0   FALSE       C-type
## 651               0.0   FALSE       C-type
## 652               0.0   FALSE       C-type
## 653               0.0    TRUE       O-type
## 654               0.2   FALSE Intermediate
## 655               0.0   FALSE       C-type
## 656               0.1   FALSE       C-type
## 657               0.0   FALSE       C-type
## 658               0.0   FALSE       C-type
## 659               0.0   FALSE       C-type
## 660               0.0   FALSE       C-type
## 661               0.0   FALSE       C-type
## 662               0.0   FALSE       C-type
## 663               0.0   FALSE       C-type
## 664               0.1   FALSE       C-type
## 665               0.1   FALSE       C-type
## 666               0.1   FALSE       C-type
## 667               0.0   FALSE       C-type
## 668               0.0    TRUE       O-type
## 669               0.2   FALSE Intermediate
## 670               0.1   FALSE       C-type
## 671               0.0   FALSE       C-type
## 672               0.1    TRUE       O-type
## 673               0.0   FALSE       C-type
## 674               0.3   FALSE Intermediate
## 675               0.0   FALSE       C-type
## 676               0.0   FALSE       C-type
## 677               0.0   FALSE       C-type
## 678               0.0   FALSE       C-type
## 679               0.0   FALSE       C-type
## 680               0.2   FALSE Intermediate
## 681               0.0   FALSE       C-type
## 682               0.0   FALSE       C-type
## 683               0.0   FALSE       C-type
## 684               0.1   FALSE       C-type
## 685               0.1   FALSE       C-type
## 686               0.0   FALSE       C-type
## 687               0.0   FALSE       C-type
## 688               0.0   FALSE       C-type
## 689               0.1   FALSE       C-type
## 690               0.0   FALSE       C-type
## 691               0.0   FALSE       C-type
## 692               0.1    TRUE       O-type
## 693               0.0   FALSE       C-type
## 694               0.0   FALSE       C-type
## 695               0.1   FALSE       C-type
## 696               0.2   FALSE Intermediate
## 697               0.2   FALSE Intermediate
## 698               0.1   FALSE       C-type
## 699               0.0   FALSE       C-type
## 700               0.0    TRUE       O-type
## 701               0.0   FALSE       C-type
## 702               0.2   FALSE Intermediate
## 703               0.0   FALSE       C-type
## 704               0.0   FALSE       C-type
## 705               0.0    TRUE       O-type
## 706               0.1   FALSE       C-type
## 707               0.3    TRUE       O-type
## 708               0.1   FALSE       C-type
## 709               0.0   FALSE       C-type
## 710               0.0   FALSE       C-type
## 711               0.0   FALSE       C-type
## 712               0.0   FALSE       C-type
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## 714               0.1   FALSE       C-type
## 715               0.0   FALSE       C-type
## 716               0.0   FALSE       C-type
## 717               0.0   FALSE       C-type
## 718               0.0   FALSE       C-type
## 719               0.2   FALSE Intermediate
## 720               0.1   FALSE       C-type
## 721               0.1   FALSE       C-type
## 722               0.1   FALSE       C-type
## 723               0.1   FALSE       C-type
## 724               0.0   FALSE       C-type
## 725               0.0   FALSE       C-type
## 726               0.1   FALSE       C-type
## 727               0.1   FALSE       C-type
## 728               0.0   FALSE       C-type
## 729               0.0    TRUE       O-type
## 730               0.0    TRUE       O-type
## 731               0.0   FALSE       C-type
## 732               0.2    TRUE       O-type
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## 735               0.0   FALSE       C-type
## 736               0.0   FALSE       C-type
## 737               0.0   FALSE       C-type
## 738               0.0   FALSE       C-type
## 739               0.0   FALSE       C-type
## 740               0.0   FALSE       C-type
## 741               0.1   FALSE       C-type
## 742               0.0   FALSE       C-type
## 743               0.1   FALSE       C-type
## 744               0.0   FALSE       C-type
## 745               0.0   FALSE       C-type
## 746               0.0   FALSE       C-type
## 747               0.0   FALSE       C-type
## 748               0.0   FALSE       C-type
## 749               0.2   FALSE Intermediate
## 750               0.0   FALSE       C-type
## 751               0.0   FALSE       C-type
## 752               0.0   FALSE       C-type
## 753               0.0   FALSE       C-type
## 754               0.1    TRUE       O-type
## 755               0.0   FALSE       C-type
## 756               0.0   FALSE       C-type
## 757               0.0   FALSE       C-type
## 758               0.0   FALSE       C-type
## 759               0.0   FALSE       C-type
## 760               0.0    TRUE       O-type
## 761               0.0   FALSE       C-type
## 762               0.0   FALSE       C-type
## 763               0.0   FALSE       C-type
## 764               0.1   FALSE       C-type
## 765               0.0   FALSE       C-type
## 766               0.0   FALSE       C-type
## 767               0.0   FALSE       C-type
## 768               0.0   FALSE       C-type
## 769               0.0   FALSE       C-type
## 770               0.1   FALSE       C-type
## 771               0.2   FALSE Intermediate
## 772               0.0   FALSE       C-type
## 773               0.0    TRUE       O-type
## 774               0.1    TRUE       O-type
## 775               0.0   FALSE       C-type
## 776               0.2   FALSE Intermediate
## 777               0.3    TRUE       O-type
## 778               0.0   FALSE       C-type
## 779               0.0   FALSE       C-type
## 780               0.0   FALSE       C-type
## 781               0.1   FALSE       C-type
## 782               0.0   FALSE       C-type
## 783               0.2    TRUE       O-type
## 784               0.0   FALSE       C-type
## 785               0.0   FALSE       C-type
## 786               0.0   FALSE       C-type
## 787               0.0    TRUE       O-type
## 788               0.0   FALSE       C-type
## 789               0.0   FALSE       C-type
## 790               0.1   FALSE       C-type
## 791               0.0   FALSE       C-type
## 792               0.1   FALSE       C-type
## 793               0.0    TRUE       O-type
## 794               0.0    TRUE       O-type
## 795               0.0   FALSE       C-type
## 796               0.0   FALSE       C-type
## 797               0.0   FALSE       C-type
## 798               0.0   FALSE       C-type
## 799               0.2   FALSE Intermediate
## 800               0.0   FALSE       C-type
## 801               0.0   FALSE       C-type
## 802               0.1   FALSE       C-type
## 803               0.0   FALSE       C-type
## 804               0.1   FALSE       C-type
## 805               0.0   FALSE       C-type
## 806               0.2   FALSE Intermediate
## 807               0.0    TRUE       O-type
## 808               0.1   FALSE       C-type
## 809               0.0   FALSE       C-type
## 810               0.0   FALSE       C-type
## 811               0.1    TRUE       O-type
## 812               0.0   FALSE       C-type
## 813               0.4   FALSE Intermediate
## 814               0.2   FALSE Intermediate
## 815               0.1   FALSE       C-type
## 816               0.1   FALSE       C-type
## 817               0.2   FALSE Intermediate
## 818               0.0   FALSE       C-type
## 819               0.1   FALSE       C-type
## 820               0.0   FALSE       C-type
## 821               0.2    TRUE       O-type
## 822               0.2   FALSE Intermediate
## 823               0.3   FALSE Intermediate
## 824               0.1   FALSE       C-type
## 825               0.3   FALSE Intermediate
## 826               0.0   FALSE       C-type
## 827               0.1   FALSE       C-type
## 828               0.0   FALSE       C-type
## 829               0.0   FALSE       C-type
## 830               0.1   FALSE       C-type
## 831               0.1   FALSE       C-type
## 832               0.0    TRUE       O-type
## 833               0.0   FALSE       C-type
## 834               0.0   FALSE       C-type
## 835               0.0   FALSE       C-type
## 836               0.0   FALSE       C-type
## 837               0.2   FALSE Intermediate
## 838               0.1    TRUE       O-type
## 839               0.0   FALSE       C-type
## 840               0.1   FALSE       C-type
## 841               0.0   FALSE       C-type
## 842               0.1    TRUE       O-type
## 843               0.3    TRUE       O-type

CRP

CRP <- as.numeric(sample_data(ps)[["Fasting.plasma.CRP..mg.L."]])
## Warning: NAs introduced by coercion
keep <- !is.na(CRP)   
ps_filt <- prune_samples(keep, ps)  
CRP_filt <- as.numeric(sample_data(ps_filt)[["Fasting.plasma.CRP..mg.L."]])
dist_bray_filt <- phyloseq::distance(ps_filt, method = "bray")
res <- BetaTREND::gradient_projection(dist_bray_filt, CRP_filt)

res
## $projection_scores
##   [1] -0.5203018289 -0.3323819750 -0.2978289638  0.0094619182  0.9095490636
##   [6] -0.6841600987 -0.1331721900 -0.1589451785 -0.4725885672 -0.0237393618
##  [11]  0.0558656017  0.2984172434 -0.2426851433  0.2187750249 -0.1776069709
##  [16]  0.8522170433 -0.2024105750 -0.1380712377 -0.6348289687 -0.0068554191
##  [21]  0.6593537464 -0.4711312948  1.1818708079  0.2150596700  0.1781595639
##  [26]  1.0182721260  0.4165496927  0.3348526432  0.3799112044 -0.5043791171
##  [31] -0.3549331567  0.5985722332 -0.3174118007 -0.2364391834 -0.0374752881
##  [36] -0.0246320938  0.5265484170 -0.9002731511  0.1381757909 -0.1180522307
##  [41] -0.4095180804  0.3788578813  0.5464867240  0.4282246838  0.6229328419
##  [46] -0.4991575842  0.1447889374  0.1660608811 -0.2431418952 -0.6272003586
##  [51] -0.4319740002 -0.5006280264 -0.6004917686 -0.5648704251  0.8064077567
##  [56] -0.4929461769 -0.0790733179 -0.1792119321 -0.2705645008 -0.0286002484
##  [61]  0.1094961968 -0.4440072279  0.7431314747 -0.3566520125 -0.1821312692
##  [66] -0.2590421052 -0.4771944082 -0.3590210539 -0.2276177849 -0.4225464363
##  [71] -0.1050672023  0.1960457461 -0.0354504026 -0.5388767591 -0.2455959092
##  [76]  0.3346725690 -0.0368187024 -0.1756539757  0.7970349577 -0.4942567607
##  [81] -0.5861147771  0.4092363467 -0.2343280606 -0.4278343365 -0.3358860689
##  [86]  0.3272046335 -0.3788525256  0.4739230843  0.4616394748 -0.4666943717
##  [91] -0.8486161150  0.2450000582 -0.7727933995 -0.4771995148 -0.6300234795
##  [96] -0.7635538315 -0.7779800593 -0.2512394649 -0.2536747251 -0.4059256652
## [101] -0.5116471766 -0.1653047261  0.0301283037 -0.6627582499 -0.0177141951
## [106] -0.2692219903 -0.1541214717 -0.0624412213  0.3427933552 -0.4722343090
## [111]  0.3651683411 -0.4632749725  0.2123637976  0.0196493498 -0.3602837474
## [116]  1.0195925873 -0.3529258484 -0.1771921648  0.3439612795 -0.3532182093
## [121] -0.3493134487 -0.2617696858  0.3497754157  0.5020043279  0.1876536986
## [126] -0.3007534258 -0.2830169500  0.1057909846  0.0050834346 -0.2889575089
## [131]  0.7792750961 -0.6259845959 -0.4723557966  0.6230977904  0.0464809567
## [136] -0.3216869075  0.2074017525 -0.0220453668  0.2577480757  0.3298811476
## [141] -0.6203087771  0.6322839614 -0.4510814036  0.0103690820 -0.7722135636
## [146] -0.3586568400  0.0234328329 -0.3259025630  0.2114172781  0.0659184813
## [151] -0.4543050294  0.1878014632  0.6680784017 -0.5040888271  0.7113914252
## [156] -0.8171955443 -0.0573069846 -0.1875726097 -0.6389669897  0.4345782840
## [161]  0.5896610156  0.3114388204  0.7131731046  0.5512182632  0.1241146606
## [166] -0.0110030719 -0.6580142096 -0.0992403560 -0.1887650583 -0.4521843955
## [171]  0.7644145449 -0.6142501648 -0.5782165058 -0.3976295221  0.7799437768
## [176] -0.1100578116  0.0778536961 -0.7200327369 -0.2607501383  0.5215225929
## [181] -0.3126327898 -0.1641275182 -0.6199242030 -0.1946010907 -0.1225753434
## [186] -0.1220631510  0.5892943439  0.4878722865  0.6543625251  1.2684496279
## [191]  0.0613909725 -0.6633440751 -0.3766712746 -0.6903294205 -0.7272871166
## [196] -0.4376686732  0.6159299184 -0.2481466339  0.0709019708  0.0549084724
## [201] -0.5744620960  0.2300458647 -0.0491883225  0.3031255409  0.0991854708
## [206]  0.0548672270  0.8301344248 -0.4733829982  0.2551910823  0.4168241910
## [211]  1.0769793093 -0.5879909010 -0.3042643423  0.2519637268 -0.5215157257
## [216]  0.3278209834 -0.2987050494  0.2442248111 -0.1072014417 -0.3260556907
## [221] -0.2067769200 -0.6754932253  0.4214570926  0.4135643817 -0.2743177205
## [226] -0.0980389014 -0.2785039770  0.2272755670  0.3424172695 -0.4999708451
## [231] -0.3550113121 -0.0178686959 -0.4830351335 -0.3144816903  0.0382018955
## [236] -0.2690240416 -0.7128016691  0.1040781791 -0.5237832189  0.1028060489
## [241]  0.2654937259 -0.4938278319  0.7814235050 -0.9913043706  0.1340790722
## [246] -0.3323353260 -0.3201058556 -0.1950730520 -0.2794413385  0.2223329251
## [251]  0.0200882845 -0.5943296245 -0.7312941600 -0.2930296488 -0.1386362881
## [256] -0.5082965911 -0.5751586502  0.3788098275 -0.7758541691  0.3742956391
## [261]  0.0527497163  0.3247605641 -0.7666099156 -0.2543826937 -0.0153873761
## [266] -0.3274683622  0.4390313069 -0.2562043874  0.1228037595  0.0950288346
## [271]  0.2165421174  0.0328854441 -0.4588234733 -0.5027026759 -0.2323480322
## [276] -0.6842650985 -0.3946738942  0.1779827113 -0.8200419536 -0.6720889812
## [281]  0.0532275015 -0.4098973149 -0.1987706345  0.3356241125  0.3879481338
## [286] -0.5743550161  0.0340064714 -0.4189471818  0.1263214110 -0.2995109446
## [291] -0.3787956130 -0.6456670001  0.6289608360 -0.6050437082 -0.7714356381
## [296] -0.1737097708 -0.3763858012 -0.1108676492 -0.0070113900 -0.1115403273
## [301]  0.0033389134 -0.6569644156 -0.3002094856 -0.6885324706 -0.6775523766
## [306] -0.3536259168  0.7045472359  0.7508532399  0.0036583856 -0.3015915822
## [311] -0.1173169108 -0.3701130615 -0.2926782983 -0.5377518537 -0.5043683819
## [316]  0.1980117064  0.2309867076 -0.4376297096  0.0044570071 -0.2941374654
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## [346] -0.1829453619 -0.4137600851 -0.0823585778 -0.8906883604 -0.5594395916
## [351] -0.4514763764 -0.2723372181 -0.6023023495 -0.2329495528 -0.4710537850
## [356] -0.5378635711 -0.3153028581  0.3166895714 -0.3443300745  0.2380516238
## [361]  0.8389494200 -0.2580814108  0.0574728098  0.3830420447 -0.7200576408
## [366] -0.6188338414 -0.8036364822 -0.7287321505  0.1224547548 -0.3376042187
## [371]  0.5785160639  0.4447176651 -0.4070931898  0.7328544594  0.0499666282
## [376] -0.7526093677  0.5083160990 -0.2349301904 -0.0410785003 -0.5286238958
## [381] -0.6390010852 -0.4874012716 -0.1068604839  0.0003328401  0.7288523625
## [386]  0.0225026021  0.3159957919 -0.3172789224 -0.4201182844 -0.7718514420
## [391]  0.2115783936 -0.2044826433 -0.3875753500  0.6936905789  0.7091242723
## [396]  0.2020393875 -0.6679824159 -0.1479784956 -0.5550516945 -0.1298661163
## [401] -0.5588847504  0.2683232832  0.1272003526 -0.7249741951 -0.6881836259
## [406]  0.5105474757  0.3470819205  0.5430393267 -0.1171660809  1.2281071427
## [411]  0.5506765042 -0.1534018452  0.3423246744  0.6489503259 -0.5594962237
## [416]  0.6832343605  0.1130491793 -0.3930973210  0.4337283496  0.5624647001
## [421] -0.5902811898 -0.1514958092 -0.2844266663 -0.5923086862  1.2779626393
## [426] -0.2044135180  0.2145314051  0.5026905370  0.7243950594 -0.0760318291
## [431]  0.1492255777  0.6698238630  0.8348592144 -0.1187655805 -0.2124801377
## [436] -0.6114206391  0.7405081306  0.8920681906  0.0795857404  0.3495933342
## [441]  0.3004334711  0.0048638845  0.6035235999 -0.4862675906  0.6089037151
## [446] -0.3106009404  0.2173904816 -0.2260458393  0.4167123742  0.0287187864
## [451]  0.4938023720 -0.7072385878 -0.0260136519 -0.5292200480  0.9669781466
## [456]  0.7314909699 -0.4449231227  0.5869124921  0.1143574331  1.2731087824
## [461] -0.3697141172 -0.3401186208  0.4089414023 -0.0590950940  0.9893343924
## [466]  0.6738656714  1.1558022313  0.5712438026 -0.2221265549  0.6526692086
## [471]  0.9922507613  0.9280563174  0.5991581592  0.3309357767  0.4314353158
## [476] -0.4936897441  0.5803258001  0.3515513070 -0.2181329581  0.6822516650
## [481]  0.7519544818  0.1040304505 -0.3231769407 -0.3528054468  0.0390987546
## [486]  0.9816276223  1.3574056253  0.6106094133  0.6737881536  0.8704297435
## [491]  0.7262587608  0.6084414631  0.2468769014  0.2923287936  0.9203681026
## [496]  0.5667633288 -0.2904777155  0.9178945821  0.8538197373 -0.8722205776
## [501]  1.1290312550  0.7993661772 -0.2574258082  0.5138584135  0.4689862142
## [506]  1.0276042285 -0.1256042627  0.1772013014  1.0482932611 -0.1378180567
## [511] -0.1996285924  0.9231504929 -0.1098010245 -0.1275986988  0.9176030764
## [516] -0.1282387048 -0.7095497381 -0.1313719758  0.4159616308  0.5382418266
## [521] -0.6054452978 -0.4936320287  0.1320791261 -0.0954684858 -0.0757513217
## [526]  0.9436096716  0.0912455620  0.3656938952 -0.3473844345 -0.1233094886
## [531] -0.0092327733  0.6826999306  0.8905214310  0.4886730894 -0.2443224958
## [536]  0.4836468253 -0.1667779758  0.3052130176 -0.4581336623  0.5850698216
## [541]  0.9892210137  0.2091219314  0.1018448050 -0.2351199586  0.5774391284
## [546] -0.3078222384  0.3250463651 -0.7024373361 -0.4730620824  0.5141294967
## [551] -0.2247564636 -0.0785677034  0.9713471751 -0.4307600267  0.9515068599
## [556]  0.2864083458 -0.9946053782  0.1614600381 -0.1643783653  0.2745366075
## [561]  0.8347858310 -0.3660595074 -0.0906155867 -0.2546491470 -0.1216637202
## [566] -0.4645364445 -0.4503546205  0.5078931037 -0.1934523042  0.4298608771
## [571] -0.2062241730  0.0929530004 -0.0533284164  0.1473313702 -0.1429223320
## [576]  0.4475449878  0.5008842058 -0.0163256459 -0.0916944756 -0.3144519582
## [581] -0.2881647288 -0.2512684909 -0.8149301937  0.4741067027  0.1837715408
## [586]  1.1731047839 -0.4128882308  0.7445070352  0.1488214677 -0.6573977665
## [591]  1.2188434856 -0.6973156668  0.0980820759  0.9053805814  0.4426270549
## [596]  0.8670587934 -0.0798923896  0.2713279087 -0.0761972080 -0.1624721839
## [601] -0.6244005218 -0.0190670888  0.6243777671 -0.1610543605 -0.2826652586
## [606]  0.7948329251 -0.2034795582 -0.5777555556  0.1339728943  0.6185886303
## [611]  0.2357291962  0.1998880902  0.5935540940  0.3540483150 -0.0980564953
## [616]  0.4372092825  0.0233357018 -0.1840428068 -0.1884085223 -0.2508394516
## [621] -0.3839339769  0.5060397934  0.6542879214 -0.4912840138  0.6902243576
## [626] -0.6100949204 -0.4124026785  0.2101341879  0.2019769002  0.5554527418
## [631]  0.4229775519 -0.2945830609  0.1628280395  0.1749614119 -1.0697190478
## [636] -0.2474276728 -0.1798964565 -0.2028028095 -0.1079702306  0.5925630306
## [641] -0.3553440417  0.2381839214 -0.2119449290  0.2208598264  0.6663772353
## [646] -0.6739444321  0.6517290128 -0.6590535012 -0.1960757185  0.0702298605
## [651] -0.2091847337  1.1478965131 -0.2833364376  0.3786442472 -0.0657573219
## [656] -0.2303786930  0.4133639715 -0.3615069575 -0.1807099863 -0.1333792644
## [661]  0.5175250918 -0.0272162121 -0.4509232693 -0.6601026696 -0.4083446280
## [666] -0.4314894544  0.2812407197 -0.1363348766  0.7420638288  0.0131568344
## [671] -0.1507917818  0.7370220250  0.8841272794 -0.6150574388 -0.0756939022
## [676]  0.4638003743  0.4043928418  0.7435487293 -0.7407228454 -0.1379453282
## [681]  0.4648177069 -0.0528618079  0.6974556905 -0.0692037470 -0.7440445031
## [686]  0.6175070661 -0.1265741135 -0.7228858077 -0.0506694110  0.5244658515
## [691] -0.6222693993 -0.7603860109  0.0863664750  0.0657382160  0.7259145199
## [696] -0.0810576633 -0.3094764063 -0.6068058224 -0.4974893272 -0.3500484391
## [701]  0.0470918809  0.2947735051 -0.3363525767 -0.5250560788 -0.0884554962
## [706] -0.6625443106  0.2265756552 -0.0764207567 -0.2039704730  1.2705747711
## [711]  0.1768717004 -0.5788929714 -0.1603434246  0.4066834644 -0.1461246676
## [716] -0.5056626232  1.0715485540 -0.1644107041  0.4605349773 -0.4476579875
## [721] -0.4224889031 -0.3468094554 -0.1786474842  0.5249240403  0.5098650139
## [726] -0.0233620339 -0.3387386157 -0.1493659725 -0.5044834638 -0.4764890547
## [731]  0.1171196933 -0.2622685096 -0.1464831872 -0.1569887621  0.4552802138
## [736]  0.2281413607 -0.4770032335 -0.4586580397 -0.0912437166 -0.0915994458
## [741] -0.3064614978 -0.0772732618 -0.7573912727  0.3492881802 -0.4754566212
## [746] -0.2368745000 -0.1913166539  0.4176361741  0.2930776529  0.3224293514
## [751]  0.4010700517  0.2057851629 -0.0867943592  0.2251955742 -0.0911764982
## [756]  0.2496499903  0.0704711861  0.6067460966 -0.1187138456  0.6723234691
## [761] -0.5440766653 -0.0508002712 -0.2225918206 -0.4008169871 -0.2816899385
## [766] -0.5840752869 -0.4410209666  0.1672684289  1.1236821969  0.1609018560
## [771]  0.3347736868  0.4663253981 -0.0814469150 -0.6231741555  0.1345576206
## [776] -0.6627256757  0.1079408550 -0.2637401906  0.0551806296 -0.1148913463
## [781] -0.0078874352 -0.3279159015 -0.6689088096  0.3384645154  0.3415554575
## [786]  0.5681929618  0.3483139538 -0.2549154285  0.3558831454  0.6261247036
## [791]  0.5182657130 -0.1531397048  0.4551980439 -0.4866521741 -0.3881978448
## [796]  0.0967344832 -0.3231600780  0.2384451082 -0.0828490294  1.0770032048
## [801] -0.0972241623  0.3683409634  0.3862775485 -0.4734403589 -0.1530224650
## [806] -0.0786425882  0.2705042543  0.9034377585 -0.0480513700 -0.0804916925
## [811]  0.6336211066  0.1771062870 -0.4118697179 -0.0762819278 -0.4082484740
## [816]  0.4743858075  0.3270260380 -0.7002842880 -0.1846258447 -0.5469619108
## [821]  0.1608835253  0.1994700043  0.3362575911 -0.2688907482 -0.6792512423
## [826] -0.3353543951  0.6327909927  0.6188639292 -0.7550938497 -0.8475080054
## [831]  0.4283543593  0.0753096991 -0.7019697094  0.1209381598  0.8783592421
## [836]  0.6724817206  0.9138862118 -0.0503678344  0.2754277613 -0.6509394425
## [841] -0.5254663608 -0.6470164071 -0.4000266446  0.1274414502  0.1828844939
## [846]  0.3570671692  0.2535784233 -0.6050065672  0.2480863579  1.2315264439
## [851]  1.0560756136
## 
## $gradient_direction
##           [,1]
## [1,] -0.366981
## [2,]  1.447554
## [3,]  1.430447
## [4,] -2.856437
## [5,] -2.235805
## 
## $PCoA_coordinates
##                     [,1]          [,2]          [,3]          [,4]
## x10MCx1146  0.2342155040 -2.629917e-01  0.0816706517  0.0400828999
## x10MCx1176 -0.1783962802 -3.034778e-02 -0.1024783301  0.0693079542
## x10MCx1206 -0.0722911135 -8.742052e-02 -0.1151697641 -0.0953497861
## x10MCx1350 -0.0388502233 -1.250913e-01 -0.0734089657 -0.1189858828
## x10MCx1390 -0.3256290034  4.056493e-02  0.1444286712 -0.1121152749
## x10MCx1529  0.0108976514 -6.848958e-02 -0.1070474606  0.1361150515
## x10MCx1563  0.2214231324 -1.885467e-01  0.4593933724  0.0309779279
## x10MCx1585 -0.0047368907 -1.630815e-01 -0.0679229890 -0.1538999506
## x10MCx1667 -0.0512743081 -5.054966e-02 -0.1150069742  0.0555365451
## x10MCx1745 -0.0993343072 -1.240995e-01 -0.1103394892 -0.0476464177
## x10MCx1810  0.1095341480 -2.740654e-01  0.0955326722 -0.1799605132
## x10MCx1936 -0.2574426373 -3.829990e-02 -0.0579003042 -0.1033255244
## x10MCx2044 -0.1862440220 -3.155080e-02 -0.0464764203  0.0508470030
## x10MCx2066 -0.2430527704  5.784722e-02  0.0389065114 -0.0059164188
## x10MCx2262  0.2557474367 -2.186492e-01  0.3973351692  0.0183481602
## x10MCx2294 -0.3357777940  1.152527e-01  0.2314135868 -0.0156929709
## x10MCx2392 -0.1571434014  5.833842e-03 -0.1137578777 -0.0211675369
## x10MCx2550  0.2522380056 -2.816529e-01  0.3596258307 -0.0667341643
## x10MCx2839 -0.0478389694 -5.047161e-02 -0.0712290985 -0.0010595264
## x10MCx2862  0.1005371268  3.681067e-01 -0.0376669312  0.0288893475
## x10MCx3024  0.3460990443  1.801926e-01 -0.0071980294 -0.1074475404
## x10MCx3098 -0.1829189153  1.655607e-01  0.1287212004  0.2229304454
## x10MCx3111 -0.3352765211  1.178708e-01  0.2610627300 -0.1006968964
## x10MCx3144 -0.1550906485 -6.845264e-03 -0.0360349710 -0.0781910019
## x10MCx3329 -0.1624510981 -6.314914e-03  0.0656028573 -0.1074921032
## x10MCx3358 -0.2667646090  6.722553e-02  0.2270997288 -0.1380763487
## x10MCx3391 -0.0820448409 -1.754461e-01  0.0273734648 -0.2796807488
## x10MCx3419  0.3358850145  1.463779e-01  0.0041495515  0.0411200218
## x13MCx1129  0.3513028641  2.067761e-01 -0.0528947836 -0.0193534353
## x13MCx1340 -0.1008903740 -7.118796e-02 -0.1542845176  0.0243074782
## x13MCx1381 -0.1469939237  1.350899e-02 -0.0855572900  0.0093166711
## x13MCx1398 -0.2008830288  2.789077e-02  0.1218177801 -0.1471835109
## x13MCx1416  0.0639878617  2.048752e-03 -0.0641852815  0.1676008584
## x13MCx1553 -0.1601579928  1.212790e-02 -0.0847711029  0.0639936917
## x13MCx1818 -0.1796225079  8.456565e-02  0.0885123814  0.0145549213
## x13MCx2054 -0.0539425696 -1.210569e-01 -0.0449155467 -0.1487282358
## x13MCx2232 -0.2921021762  1.299813e-01  0.1635763951 -0.0093281668
## x13MCx2282 -0.0502432527 -4.480954e-02 -0.1401227948  0.1207752649
## x13MCx2401 -0.2369855221 -1.578354e-02 -0.0786614256 -0.0674106722
## x13MCx2621  0.2592741670  1.854458e-01 -0.0896203354  0.1050319835
## x13MCx2699 -0.1857757104  2.219041e-03 -0.1132878996  0.0549731722
## x13MCx2743  0.3381414928  3.317736e-01 -0.0447074486 -0.0757771698
## x13MCx2963 -0.2667958964  1.142270e-01  0.1978383397 -0.0080897323
## x13MCx2965  0.4038303070  1.213607e-01  0.0107166897 -0.0117215108
## x13MCx3205  0.3658154478  3.618257e-01  0.0512444733 -0.0360492510
## x13MCx3311 -0.0037618007 -1.202001e-01 -0.1158306454 -0.0580899242
## x13MCx3383  0.1187167102  3.699469e-01 -0.0391150820 -0.0537754847
## x14MCx1118 -0.2428719283 -2.258972e-02 -0.0353049501  0.0294206938
## x14MCx1158 -0.0012170062 -1.841720e-01 -0.1124480563 -0.0553447912
## x14MCx1190  0.0651564597 -1.746425e-01 -0.1173604121  0.0379738154
## x14MCx1209  0.0616214044 -1.045780e-01 -0.1092303686  0.0722479626
## x14MCx1227  0.0502910228 -1.922405e-01 -0.0974060900 -0.0402482706
## x14MCx1302  0.1022999100 -2.203933e-01 -0.0577554550  0.0605517217
## x14MCx1313 -0.0796701236 -4.409643e-02 -0.1333663709  0.0522547734
## x14MCx1363  0.3857142642  3.902643e-01  0.0485289130 -0.1536606530
## x14MCx1397  0.1541666791 -1.741723e-01 -0.0414410631  0.0178348720
## x14MCx1399  0.3088323852 -1.308946e-01  0.0985246595  0.0166548256
## x14MCx1485  0.2387222379 -2.140638e-01  0.4696572381  0.0204300357
## x14MCx1540 -0.1372720778 -9.844520e-02 -0.1346883324 -0.0215717661
## x14MCx1551  0.3063255075  1.000634e-03 -0.0403931258  0.0569521994
## x14MCx1578 -0.1953324324 -2.554589e-02 -0.0632544684 -0.0682221037
## x14MCx1583  0.0176318278 -1.915522e-01 -0.0877830409 -0.0614950965
## x14MCx1612 -0.2753424752  2.699179e-02  0.0970354811 -0.1416349639
## x14MCx1616  0.0374734502 -1.792206e-01 -0.0956361022 -0.0440222631
## x14MCx1621  0.2118556500 -1.739958e-01 -0.0162322931  0.0271681384
## x14MCx1706  0.1582629272 -3.015679e-01  0.0634661641 -0.0812413323
## x14MCx1724 -0.0138217532 -1.737235e-01 -0.1133483190  0.0306086704
## x14MCx1739  0.0586655816 -2.110909e-01 -0.0617975394 -0.0486328544
## x14MCx1747 -0.1848518645 -1.410976e-02 -0.0478710701 -0.0050605126
## x14MCx1768  0.2207414968 -1.771049e-01 -0.0534266911  0.0369841357
## x14MCx1775  0.3329476287 -2.320449e-01  0.2722582366  0.0166497513
## x14MCx1798  0.3228185446 -1.492369e-01  0.1877569987 -0.0154188596
## x14MCx1861  0.0192137099  3.707097e-01 -0.0462369220  0.0292034301
## x14MCx1910  0.1327279968 -1.960557e-01 -0.0405943709  0.0642965711
## x14MCx1914  0.0105391395 -1.733652e-01 -0.0616212417 -0.0948179347
## x14MCx1916 -0.1762249361 -7.751736e-02  0.0066612618  0.0068413244
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## x14MCx1953  0.1002880893 -2.167729e-01 -0.1128455239 -0.0664577367
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## x20MCx1780  0.3238188873  2.190991e-01 -0.0303748276 -0.0538674899
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## x20MCx2016  0.0528432460  2.310150e-03 -0.1287181758  0.1260689634
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## x20MCx2857  0.0968640648  3.469297e-01 -0.0730684447 -0.1025970335
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## x20MCx2896  0.1949557953  1.999154e-01 -0.1240484986  0.0164727464
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## x20MCx2975 -0.3195608359  6.013305e-02  0.0176739327 -0.0085794389
## x20MCx2988 -0.1956214347 -7.489754e-02 -0.0366594487 -0.1546104651
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## x20MCx3094 -0.1776911091 -8.571671e-02 -0.0292193891 -0.1826841505
## x20MCx3099 -0.1847286299  2.516541e-02 -0.0685462080  0.1651789322
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## x30MCx1112 -0.2329381410  3.987927e-03  0.0230164774 -0.1119397938
## x30MCx1116  0.2891811379  3.604149e-02  0.0076357688  0.2062315636
## x30MCx1163  0.1892348524  7.249533e-02 -0.1418101678  0.0799184744
## x30MCx1170  0.1016278914 -1.206545e-01 -0.0974970576 -0.0200850376
## x30MCx1172 -0.2368304044 -4.592235e-02 -0.0642443950 -0.0743480845
## x30MCx1180 -0.2058338826 -6.093813e-02 -0.0227933032 -0.1309712209
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## x30MCx1226 -0.0357102648 -1.538374e-01 -0.0881462982  0.0690726101
## x30MCx1235 -0.1876072786 -2.926412e-02 -0.1367878318  0.0121745837
## x30MCx1259  0.1327249282 -2.037013e-03 -0.1474086940 -0.0333424108
## x30MCx1266  0.2811965871 -2.900713e-01  0.3490009805 -0.0041226152
## x30MCx1270 -0.0673362854 -5.428711e-02 -0.1188174458  0.1357797219
## x30MCx1280  0.0244458697 -2.476527e-01  0.0859365595 -0.2166298873
## x30MCx1308  0.0008511261 -1.348435e-01 -0.0778782795  0.1171988536
## x30MCx1314  0.3038629417  3.104669e-02 -0.0442379866  0.0496751128
## x30MCx1321  0.3414192396  3.971445e-02 -0.0470418529 -0.0256250566
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## x30MCx1394 -0.3229585033  1.148206e-01  0.1720778591 -0.0510729211
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## x30MCx1415 -0.1095931449 -1.780733e-01 -0.0574477438 -0.1392429459
## x30MCx1417 -0.0281411457 -1.381858e-01 -0.1086613980 -0.0135541521
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## x30MCx1479  0.1238742072  3.968095e-01 -0.0124081110  0.0639244700
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## x30MCx1911  0.1589026634  3.671196e-01 -0.0612899702  0.0357714324
## x30MCx1917 -0.2023079136  3.288741e-02 -0.0414888758  0.1136795315
## x30MCx1966 -0.0908411978 -1.351430e-01 -0.1123214533 -0.0532271393
## x30MCx1972  0.3731906912  1.849086e-01  0.0182264883  0.0777562770
## x30MCx1980  0.2683877183  2.940643e-01 -0.0648040688 -0.1037272490
## x30MCx1993  0.1790802631 -1.222514e-01 -0.0220428032  0.1805009880
## x30MCx1996 -0.1234764502 -1.196784e-01 -0.0863027786 -0.0696968710
## x30MCx2009 -0.1056280981 -9.778719e-02 -0.1168428450 -0.0062379914
## x30MCx2015  0.2225574536 -9.033355e-02  0.4809620001  0.0383345427
## x30MCx2022  0.3300103362 -1.621357e-01  0.1271458760  0.1132143215
## x30MCx2041  0.2211859421 -2.906288e-01  0.0840714868 -0.0386208363
## x30MCx2081  0.0926490269 -1.991213e-01 -0.1074398356  0.0834306312
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## x30MCx2107  0.0462405301 -1.914476e-01  0.0086799722  0.0196390705
## x30MCx2131 -0.2482907654  5.932331e-02 -0.0503301053  0.1104728286
## x30MCx2132 -0.0743108582 -9.968718e-02 -0.1167245927 -0.0428461560
## x30MCx2140  0.2748604122 -9.543400e-02 -0.0259152596 -0.0140365051
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## x30MCx2158  0.0720124308 -1.545893e-01 -0.0614418287 -0.1533312707
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## x30MCx2168  0.1463222855 -3.000465e-01  0.0653188021 -0.0667831018
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## x30MCx2605  0.0119032798 -7.455696e-02 -0.0506548627  0.0498753791
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## x30MCx2819  0.2808828618 -2.558361e-01  0.2853856774  0.0695562513
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## x30MCx3237 -0.0441136198 -1.134340e-01 -0.1059557148 -0.0058273317
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## x30MCx3369  0.3414098614 -1.285048e-01  0.0642356356 -0.0753548759
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## x30MCx3379 -0.1745976201  2.744979e-02 -0.0930505653  0.1893174168
## x30MCx3384  0.3697646526  1.563824e-01  0.0014208255 -0.0077773824
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## x10MCx1330 -0.2669468680  3.049673e-02  0.0609139800 -0.0496664547
## x10MCx1333  0.1744794654  3.175436e-01 -0.0739754652 -0.1721321926
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## x10MCx1365  0.0126165249 -2.061370e-01 -0.0568737616 -0.1693421722
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## x10MCx1685 -0.0027450092  1.627367e-02 -0.1215950037  0.0576557220
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## x10MCx1877  0.1927323884  2.578054e-01 -0.0985020864 -0.0229532005
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## x10MCx2060  0.2585954441  1.705132e-01 -0.1324841852 -0.0696582195
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## x10MCx2157 -0.1878286240  7.999645e-03 -0.0246480406 -0.0761165791
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## x10MCx3277 -0.3225919347  4.885122e-02  0.1259468853 -0.1115618247
## x10MCx3287 -0.1715261082  1.696460e-02  0.1374364361 -0.1833216896
## x10MCx3318  0.1384975795  2.480217e-01 -0.0919621345 -0.1397994553
## x10MCx3322  0.1264076997  2.553623e-01 -0.1446453906 -0.1059419303
## x11MCx1159 -0.2106082920  5.186259e-02  0.1250008224  0.0632148375
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## x11MCx1383 -0.3056395970  3.245739e-02  0.0524656838 -0.0910866523
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## x11MCx1588 -0.3126976040 -2.392518e-03  0.0746908397 -0.1244525402
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## x12MCx1480 -0.1173657343  3.166659e-01  0.2125049531  0.0681097496
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## x12MCx1642  0.4166438015  1.609999e-02  0.0928752060 -0.0846033565
## x12MCx1651  0.4383136704  2.818881e-01  0.0915805705 -0.1243591859
## x12MCx1652 -0.0738142103  3.331498e-02 -0.0599294602 -0.0688782731
## x12MCx1672 -0.2533342172  1.844615e-01  0.2390429282  0.1885458427
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## x12MCx1771 -0.2999668722  1.827751e-01  0.2490964448  0.1343985576
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## x12MCx1869  0.0542029822  1.200856e-01 -0.1449587355 -0.1759278282
## x12MCx1886  0.2375880127 -2.450187e-01  0.1057851242 -0.0210658918
## x12MCx1893 -0.2915659117  1.262963e-01  0.0982044177  0.1560279100
## x12MCx1895 -0.1436519689  1.824585e-01  0.0119446901 -0.1550619045
## x12MCx1903 -0.1403353958  7.104348e-03 -0.0667837085  0.1589664951
## x12MCx1909 -0.3223857184  8.478866e-02  0.1582264082 -0.1068880460
## x12MCx1922 -0.1340057822 -5.413454e-03 -0.0722548489 -0.0661751949
## x12MCx1988  0.0959201751 -1.691149e-02 -0.0911349685  0.2636633846
## x12MCx2002  0.1636389091  3.218868e-01 -0.0946620105 -0.0663642905
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## x12MCx2136  0.3961643022  2.756557e-01  0.0061009395 -0.1608322562
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## x12MCx2202 -0.0504002984  3.206920e-01  0.0864975067  0.1609966134
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## x12MCx2285 -0.1867022557  1.164416e-01  0.0031614679  0.1765831079
## x12MCx2291  0.1327057276 -2.482256e-01 -0.0561621891 -0.0594843928
## x12MCx2317 -0.2649469029  6.025574e-02  0.0530973776 -0.0399656408
## x12MCx2321 -0.0279521296  6.429447e-02 -0.0281679253  0.0310917975
## x12MCx2323 -0.1260691556  1.053802e-02 -0.0174372980 -0.0145358598
## x12MCx2347 -0.1140592667 -9.886886e-02 -0.1194121933 -0.0661827871
## x12MCx2380  0.2455761680  4.188516e-01  0.0637606258  0.0468200588
## x12MCx2447  0.1492059750 -2.542995e-01  0.1182037626 -0.1768523560
## x12MCx2454  0.0308758316 -2.296070e-01 -0.0186770075 -0.2329495683
## x12MCx2489 -0.2290524131  1.911753e-02 -0.0547054408  0.0181320430
## x12MCx2496  0.0097924116  2.443313e-01 -0.1234299490 -0.1356761275
## x12MCx2522 -0.2470118452  1.608848e-01  0.3320226014  0.1536949528
## x12MCx2576  0.2200048066  2.932748e-01 -0.1260618028  0.0032194648
## x12MCx2667  0.1830411676  1.208037e-01 -0.1224527552  0.0998853837
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## x12MCx2736  0.0116692388  5.094645e-02 -0.1533789363  0.0668718358
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## x12MCx2798  0.0949948702  3.205875e-01 -0.0604172655 -0.1441063404
## x12MCx2849  0.3031541448 -1.026936e-01  0.3563896219  0.0435905474
## x12MCx2993  0.4612685653  2.288120e-01  0.1385697177 -0.1862709473
## x12MCx3006  0.1034275774  8.471228e-02 -0.1410889882  0.1245581319
## x12MCx3026  0.3594104868  4.538169e-02  0.3447286906  0.0123101215
## x12MCx3046 -0.2500404206 -1.330970e-03 -0.0590922264 -0.0193690173
## x12MCx3072  0.0682966010 -1.054994e-01 -0.0864562721  0.1598674390
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## x12MCx3113  0.1468201633 -1.520682e-01 -0.0430152072  0.1696649762
## x12MCx3117 -0.1283393498 -3.240143e-02 -0.0080603559  0.0091984726
## x12MCx3125 -0.2837701264  1.126618e-02  0.1536483001 -0.0274441988
## x12MCx3230 -0.0403625278 -2.028340e-01  0.1179308540 -0.2822341584
## x12MCx3272  0.4293387190  3.852395e-01  0.0595552889 -0.0999557165
## x12MCx3309 -0.0350698075  3.309841e-01  0.1301016056  0.1787718737
## x12MCx3333 -0.0091265757  1.711738e-01 -0.0510508589  0.0156487087
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## x12MCx3392  0.2785284219  2.178233e-01  0.0150994280  0.1525097888
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## x13MCx1231  0.0037904674  4.134341e-02 -0.1659562501  0.0158015050
## x13MCx1299 -0.2255750146 -8.781254e-02  0.0067470163 -0.2455224295
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## x13MCx2071 -0.1019049899  1.386654e-01  0.3387407097  0.1757922643
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## x13MCx2229 -0.2764784180  4.951844e-02 -0.0031528587 -0.0199217423
## x13MCx2582  0.0955544444 -2.646309e-01 -0.0001831743 -0.0859739869
## x13MCx3092  0.3403509158  3.105581e-01 -0.0490486058 -0.1340612599
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## x14MCx1338  0.0789453729  7.824342e-02 -0.1487447885  0.0237490533
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## x14MCx2102 -0.0368917022 -1.052438e-01 -0.1094059849 -0.0683251985
## x14MCx2548  0.3427699953  2.347777e-01 -0.0602310194 -0.1356381681
## x14MCx2875  0.3396800092  3.500535e-01 -0.0089358995 -0.1520791977
## x30MCx1130 -0.0271843948 -1.306542e-01 -0.1206048815  0.0134056808
## x30MCx1137  0.3780830784  5.671186e-02  0.0861106150 -0.0809734375
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## x30MCx1169 -0.1087422503  2.017511e-01  0.1660964286  0.3040846229
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## x30MCx1188 -0.3049439671  1.344182e-01  0.0692269984  0.0879517194
## x30MCx1195  0.3872807108  2.160088e-01 -0.0413583494 -0.1052821192
## x30MCx1197  0.0592229530  3.123016e-01 -0.1043024520 -0.1217238672
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## x30MCx1217 -0.1835369638 -6.109668e-03 -0.0346604614  0.0797623043
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## x30MCx1271  0.2746829762  3.130651e-02 -0.0290054675 -0.1160833102
## x30MCx1276  0.2133966778 -2.803247e-01  0.0798981578 -0.0683366245
## x30MCx1293  0.1552765037  2.926762e-01 -0.1117003134 -0.1060658768
## x30MCx1296 -0.1801956944 -2.206438e-03 -0.0878300420  0.0584674494
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## x30MCx1331 -0.3339632615  1.474920e-01  0.2391483263  0.0755379623
## x30MCx1346 -0.0538144594 -3.204753e-02 -0.1316816690  0.0694677486
## x30MCx1358 -0.2896947301  1.540188e-02  0.0502496294 -0.0824904475
## x30MCx1370  0.1562482762 -1.404862e-01 -0.0337962649  0.1844123778
## x30MCx1371 -0.1458139376 -5.536370e-02 -0.0817091907 -0.0042429416
## x30MCx1372 -0.0340327985 -1.078364e-01 -0.0685707544 -0.1259653029
## x30MCx1380  0.2326396941 -2.526373e-01  0.2680782893 -0.0452147453
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## x30MCx1401 -0.0994369902  2.167612e-02 -0.0745469024  0.1000676532
## x30MCx1406 -0.2319593876  5.301630e-02  0.0471134374 -0.0485323696
## x30MCx1423 -0.0614470859  1.808387e-01 -0.0913299780  0.0795607190
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## x30MCx1430 -0.2234299824  2.427271e-01  0.2403853530  0.1604149019
## x30MCx1449 -0.1514764115  1.507825e-02 -0.0805615369  0.0782640164
## x30MCx1452 -0.2178625623  2.536739e-02 -0.0055445405  0.1220773672
## x30MCx1461  0.0838493744  3.462590e-01  0.1120321866  0.1230550527
## x30MCx1474 -0.3014853596  1.691407e-01  0.2877525699  0.1371458982
## x30MCx1477 -0.1264891990 -7.594754e-02 -0.0142802322 -0.0097529546
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## x30MCx1522  0.0794526279 -2.149838e-01 -0.1207291669  0.0640327447
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## x30MCx1525 -0.0059390309 -1.381135e-01 -0.1487702222 -0.0205956082
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## x30MCx1554 -0.2208277114  9.629335e-02  0.1161526034  0.2407932507
## x30MCx1573 -0.3228377664  4.766523e-02  0.0869346592 -0.0697373472
## x30MCx1575  0.2698373453  1.826253e-01 -0.0802604073  0.0604322507
## x30MCx1590  0.2595574230 -2.260293e-01  0.4447800278  0.0166125350
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## x30MCx1662 -0.3375239176  1.373049e-01  0.1421253427  0.0297035686
## x30MCx1674 -0.3067374239  1.859759e-01  0.2787844687  0.1352374134
## x30MCx1682  0.3351099845  3.663292e-01  0.0361553547 -0.1040609783
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## x30MCx1686 -0.2634598857  5.519003e-02 -0.0361664437  0.0491059567
## x30MCx1688 -0.3204331943  1.763023e-01  0.2594524797  0.1312690506
## x30MCx1691  0.0351977746  9.968863e-02 -0.1691085632 -0.0024499115
## x30MCx1696 -0.3097382338  5.323109e-02  0.0850922044 -0.0877255081
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## x30MCx1741  0.0089086635  1.915646e-01 -0.0756940679 -0.1119810779
## x30MCx1750 -0.1535128385  1.970848e-01  0.1753885207  0.2472802949
## x30MCx1754  0.0420634421 -1.282751e-01 -0.1414790767  0.0572083740
## x30MCx1761  0.0022646876 -1.932143e-01 -0.0622477165 -0.0155944678
## x30MCx1762 -0.1843846246  2.044582e-01  0.2708961467  0.1534534644
## x30MCx1765 -0.0682011562  8.880878e-03 -0.0432014336  0.2332600453
## x30MCx1767 -0.0604416036  1.054743e-03 -0.1122198352  0.2047452330
## x30MCx1779 -0.1191337830 -1.369588e-01 -0.0359451365 -0.0974881593
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## x30MCx1195 -0.0641031400
## x30MCx1197  0.0920740313
## x30MCx1199 -0.0179486327
## x30MCx1204 -0.0199772575
## x30MCx1210 -0.0100411646
## x30MCx1214  0.0479498359
## x30MCx1217  0.0127570070
## x30MCx1248 -0.0717822837
## x30MCx1253  0.0882268797
## x30MCx1262  0.0555760482
## x30MCx1271 -0.1601010209
## x30MCx1276  0.0808370022
## x30MCx1293  0.1215161263
## x30MCx1296 -0.0079458931
## x30MCx1312  0.0622468361
## x30MCx1331 -0.0912408966
## x30MCx1346  0.1165167842
## x30MCx1358 -0.0964365171
## x30MCx1370 -0.0790561970
## x30MCx1371  0.0289308403
## x30MCx1372  0.0214176139
## x30MCx1380  0.1210880190
## x30MCx1400 -0.1380469219
## x30MCx1401 -0.0184573882
## x30MCx1406 -0.0048092878
## x30MCx1423 -0.0034984726
## x30MCx1425  0.0904095561
## x30MCx1430 -0.0422064531
## x30MCx1449  0.0447835123
## x30MCx1452 -0.0265029622
## x30MCx1461  0.1845392659
## x30MCx1474 -0.0635919222
## x30MCx1477 -0.0129131313
## x30MCx1509  0.0233456199
## x30MCx1522 -0.0160380227
## x30MCx1524 -0.1040015630
## x30MCx1525  0.0356759034
## x30MCx1544  0.1272791058
## x30MCx1554 -0.0737525867
## x30MCx1573 -0.1033340022
## x30MCx1575 -0.0604933223
## x30MCx1590  0.1418420498
## x30MCx1594 -0.1049168477
## x30MCx1607 -0.1438867316
## x30MCx1609  0.0130120101
## x30MCx1644  0.0071527190
## x30MCx1662 -0.0101631494
## x30MCx1674 -0.0045292946
## x30MCx1682  0.0056872876
## x30MCx1683  0.0889962237
## x30MCx1686  0.0547983250
## x30MCx1688 -0.0428688520
## x30MCx1691 -0.0226555004
## x30MCx1696 -0.0601261841
## x30MCx1701  0.1332527207
## x30MCx1707 -0.0146927958
## x30MCx1741 -0.0589879998
## x30MCx1750  0.0057002191
## x30MCx1754  0.0697617819
## x30MCx1761 -0.1227062607
## x30MCx1762 -0.0946698938
## x30MCx1765 -0.0303857527
## x30MCx1767  0.0173213768
## x30MCx1779 -0.0061949253
## x30MCx1796 -0.0096625841
## x30MCx1813  0.0471254582
## x30MCx1832  0.0386147400
## x30MCx1838  0.0830154965
## x30MCx1840  0.0984970711
## x30MCx1851 -0.0214382691
## x30MCx1852 -0.0690695347
## x30MCx1856 -0.0046195207
## x30MCx1885 -0.0223216213
## x30MCx1902 -0.0144937016
## x30MCx1919  0.0712771328
## x30MCx1924  0.1441400454
## x30MCx1930  0.0316495409
## x30MCx1935 -0.1175665743
## x30MCx1938  0.1460618431
## x30MCx1942  0.0389116147
## x30MCx1956 -0.1875891575
## x30MCx1957  0.1209293688
## x30MCx1969 -0.0479446977
## x30MCx1975 -0.1717270019
## x30MCx1976  0.0979577385
## x30MCx1987  0.2058481262
## x30MCx1990 -0.0240512893
## x30MCx2004 -0.2029056762
## x30MCx2020  0.0514572764
## x30MCx2023  0.0980096979
## x30MCx2052  0.0066510892
## x30MCx2065  0.0839311331
## x30MCx2075  0.0648200252
## x30MCx2080 -0.0135298532
## x30MCx2082 -0.0565275394
## x30MCx2089 -0.0711790399
## x30MCx2116  0.1441331082
## x30MCx2121 -0.0019813338
## x30MCx2128  0.0774422352
## x30MCx2137  0.0152535947
## x30MCx2154  0.0535978149
## x30MCx2156  0.0094997089
## x30MCx2164  0.0732185339
## x30MCx2165  0.0454054058
## x30MCx2180  0.0407990059
## x30MCx2181 -0.1266771700
## x30MCx2197  0.0257573475
## x30MCx2222 -0.0463290279
## x30MCx2226 -0.0220036998
## x30MCx2241  0.0724753113
## x30MCx2255 -0.0378185235
## x30MCx2261  0.1378794259
## x30MCx2280 -0.0393753972
## x30MCx2296  0.1374199353
## x30MCx2303 -0.0576431976
## x30MCx2308  0.0410456119
## x30MCx2314 -0.0889925000
## x30MCx2318 -0.1125932498
## x30MCx2364  0.0591394224
## x30MCx2369  0.1327581049
## x30MCx2394 -0.1850458427
## x30MCx2403 -0.0161735599
## x30MCx2410  0.0379445074
## x30MCx2418  0.1717628475
## x30MCx2432 -0.1363144083
## x30MCx2434  0.0675560584
## x30MCx2488 -0.0517819142
## x30MCx2512 -0.0523350270
## x30MCx2515 -0.0113607928
## x30MCx2516 -0.1606220875
## x30MCx2532 -0.0135977864
## x30MCx2549 -0.0454889879
## x30MCx2554  0.0095868705
## x30MCx2558  0.0123404106
## x30MCx2567  0.0951659745
## x30MCx2584  0.0324782019
## x30MCx2586  0.0945392402
## x30MCx2592  0.0924262966
## x30MCx2595  0.0253083315
## x30MCx2618  0.0300773655
## x30MCx2648 -0.0491957537
## x30MCx2656  0.0323192037
## x30MCx2671 -0.0924007706
## x30MCx2684 -0.1231754439
## x30MCx2690  0.1099014217
## x30MCx2715 -0.0478343642
## x30MCx2719  0.1231414076
## x30MCx2723  0.0478052284
## x30MCx2724  0.0034502868
## x30MCx2727 -0.0664986580
## x30MCx2731  0.1942396781
## x30MCx2774  0.1695610508
## x30MCx2780  0.0532061320
## x30MCx2785 -0.0690399479
## x30MCx2788  0.0258840803
## x30MCx2792 -0.0039747985
## x30MCx2836 -0.1612644118
## x30MCx2837  0.1420065329
## x30MCx2855  0.0720331749
## x30MCx2871  0.0222970766
## x30MCx2890 -0.0874596066
## x30MCx2898  0.0077563041
## x30MCx2935  0.0413366729
## x30MCx2940 -0.1274290887
## x30MCx2944  0.1351034780
## x30MCx2953 -0.0564032111
## x30MCx2956 -0.0095177417
## x30MCx2958  0.0640459866
## x30MCx2970 -0.0497521565
## x30MCx2974  0.0493576046
## x30MCx2977 -0.2089372659
## x30MCx2982  0.1138062435
## x30MCx2983 -0.0492253669
## x30MCx3003 -0.0571498790
## x30MCx3007  0.0993355690
## x30MCx3015  0.0587588937
## x30MCx3018 -0.0626625702
## x30MCx3038 -0.0566024684
## x30MCx3045  0.1004793042
## x30MCx3053  0.1712871391
## x30MCx3064 -0.0052592223
## x30MCx3066  0.0454733678
## x30MCx3087  0.0688473676
## x30MCx3120  0.0436501633
## x30MCx3131 -0.0639129818
## x30MCx3137  0.0115579483
## x30MCx3143 -0.1374101957
## x30MCx3147 -0.0481770571
## x30MCx3154 -0.0470212864
## x30MCx3155  0.0410623468
## x30MCx3161  0.0571207026
## x30MCx3186  0.0441722657
## x30MCx3187  0.0658340831
## x30MCx3203  0.1465424076
## x30MCx3208 -0.0520402182
## x30MCx3215  0.1082860303
## x30MCx3220 -0.0154280581
## x30MCx3225 -0.0200949721
## x30MCx3244 -0.0305087156
## x30MCx3249  0.0290803544
## x30MCx3256 -0.0568424183
## x30MCx3259 -0.0510621965
## x30MCx3260 -0.0768679218
## x30MCx3270  0.0294447055
## x30MCx3279  0.0848080205
## x30MCx3285 -0.1633044310
## x30MCx3297 -0.0907106728
## x30MCx3305 -0.0450720969
## x30MCx3353  0.1734623003
## x30MCx3360 -0.1409350210
## x30MCx3367 -0.0323576219
## x30MCx3372  0.1623117326
## x30MCx3382  0.0263018157
## x30MCx1731  0.0462516341
## x30MCx2868 -0.0640751007
## x30MCx3184  0.0317222988
## x10MCx1626 -0.0422997213
## x10MCx2535  0.1349199338
## x12MCx1124 -0.0457534278
## x12MCx2938 -0.1555076132
## x12MCx2996 -0.0941662853
## x12MCx3165 -0.1265054297
## 
## $adjusted_R2
## [1] -0.002684849
## 
## $p_value
##     value 
## 0.7423793 
## 
## $plot

## 
## $variance_explained
##   [1]  1.314699e-01  8.842354e-02  6.124681e-02  4.034185e-02  2.259926e-02
##   [6]  2.127933e-02  1.825283e-02  1.653879e-02  1.468290e-02  1.457803e-02
##  [11]  1.353184e-02  1.208057e-02  1.174545e-02  1.097855e-02  1.077944e-02
##  [16]  9.508684e-03  9.209229e-03  8.649349e-03  8.469234e-03  8.023276e-03
##  [21]  7.927708e-03  7.572509e-03  7.080797e-03  6.968970e-03  6.937389e-03
##  [26]  6.841122e-03  6.344816e-03  6.259252e-03  6.143416e-03  6.005424e-03
##  [31]  5.902545e-03  5.666485e-03  5.563051e-03  5.449306e-03  5.233438e-03
##  [36]  5.169883e-03  5.085238e-03  4.930429e-03  4.866581e-03  4.795902e-03
##  [41]  4.699904e-03  4.562803e-03  4.468321e-03  4.383375e-03  4.302317e-03
##  [46]  4.272946e-03  4.209890e-03  4.120963e-03  3.976904e-03  3.893384e-03
##  [51]  3.855745e-03  3.747808e-03  3.703225e-03  3.611454e-03  3.487230e-03
##  [56]  3.411148e-03  3.393556e-03  3.323555e-03  3.306723e-03  3.283075e-03
##  [61]  3.216386e-03  3.181024e-03  3.131786e-03  3.075980e-03  3.054283e-03
##  [66]  2.958302e-03  2.857161e-03  2.848556e-03  2.802260e-03  2.776815e-03
##  [71]  2.721961e-03  2.694312e-03  2.682231e-03  2.604810e-03  2.590139e-03
##  [76]  2.576101e-03  2.553534e-03  2.490762e-03  2.481066e-03  2.424826e-03
##  [81]  2.402881e-03  2.381651e-03  2.339643e-03  2.299997e-03  2.279323e-03
##  [86]  2.246926e-03  2.209890e-03  2.185727e-03  2.137435e-03  2.110583e-03
##  [91]  2.098238e-03  2.093571e-03  2.048961e-03  2.023716e-03  2.010536e-03
##  [96]  1.992338e-03  1.980130e-03  1.972297e-03  1.928925e-03  1.882837e-03
## [101]  1.881612e-03  1.862070e-03  1.837239e-03  1.800598e-03  1.798673e-03
## [106]  1.779723e-03  1.738394e-03  1.716205e-03  1.702427e-03  1.689687e-03
## [111]  1.663599e-03  1.642748e-03  1.628808e-03  1.621388e-03  1.614827e-03
## [116]  1.593289e-03  1.559669e-03  1.556064e-03  1.540703e-03  1.526353e-03
## [121]  1.498022e-03  1.488249e-03  1.456834e-03  1.449767e-03  1.424841e-03
## [126]  1.424029e-03  1.411458e-03  1.404851e-03  1.383990e-03  1.365567e-03
## [131]  1.360611e-03  1.335809e-03  1.312837e-03  1.308741e-03  1.291634e-03
## [136]  1.277567e-03  1.274181e-03  1.265087e-03  1.259748e-03  1.245953e-03
## [141]  1.241092e-03  1.229979e-03  1.218932e-03  1.204102e-03  1.194960e-03
## [146]  1.167646e-03  1.164720e-03  1.150749e-03  1.131041e-03  1.130576e-03
## [151]  1.114655e-03  1.105884e-03  1.096960e-03  1.087233e-03  1.079721e-03
## [156]  1.076218e-03  1.065909e-03  1.057830e-03  1.038968e-03  1.037503e-03
## [161]  1.020840e-03  1.007333e-03  9.884658e-04  9.813090e-04  9.737656e-04
## [166]  9.701272e-04  9.526241e-04  9.442068e-04  9.322822e-04  9.308758e-04
## [171]  9.242388e-04  9.171854e-04  9.070947e-04  8.922185e-04  8.908531e-04
## [176]  8.760153e-04  8.694290e-04  8.586825e-04  8.496822e-04  8.480781e-04
## [181]  8.416252e-04  8.290188e-04  8.232547e-04  8.141731e-04  8.071283e-04
## [186]  7.976936e-04  7.903002e-04  7.843167e-04  7.763836e-04  7.691639e-04
## [191]  7.654684e-04  7.578182e-04  7.509120e-04  7.395877e-04  7.319779e-04
## [196]  7.290850e-04  7.204810e-04  7.109485e-04  7.001973e-04  6.885630e-04
## [201]  6.864031e-04  6.807149e-04  6.786988e-04  6.708016e-04  6.662925e-04
## [206]  6.602932e-04  6.559224e-04  6.541526e-04  6.478718e-04  6.387277e-04
## [211]  6.354972e-04  6.299279e-04  6.163321e-04  6.147473e-04  6.114547e-04
## [216]  6.052829e-04  5.924305e-04  5.909764e-04  5.805227e-04  5.754497e-04
## [221]  5.703854e-04  5.638124e-04  5.626615e-04  5.556609e-04  5.476739e-04
## [226]  5.442227e-04  5.414301e-04  5.381804e-04  5.311086e-04  5.238106e-04
## [231]  5.210845e-04  5.133311e-04  5.093310e-04  5.006217e-04  4.973878e-04
## [236]  4.936857e-04  4.827266e-04  4.783067e-04  4.724141e-04  4.683247e-04
## [241]  4.671771e-04  4.578636e-04  4.514749e-04  4.489436e-04  4.448302e-04
## [246]  4.421458e-04  4.389128e-04  4.313680e-04  4.244789e-04  4.224381e-04
## [251]  4.178751e-04  4.154177e-04  4.104084e-04  4.039937e-04  4.016339e-04
## [256]  4.004373e-04  3.915843e-04  3.848338e-04  3.798894e-04  3.757435e-04
## [261]  3.676664e-04  3.667096e-04  3.658856e-04  3.608430e-04  3.567155e-04
## [266]  3.534398e-04  3.514782e-04  3.472891e-04  3.429035e-04  3.387205e-04
## [271]  3.340752e-04  3.332095e-04  3.266731e-04  3.231636e-04  3.210704e-04
## [276]  3.139059e-04  3.101791e-04  3.071479e-04  3.038935e-04  2.977167e-04
## [281]  2.962933e-04  2.939464e-04  2.911219e-04  2.895852e-04  2.841697e-04
## [286]  2.819593e-04  2.778679e-04  2.767972e-04  2.702921e-04  2.690052e-04
## [291]  2.643352e-04  2.629466e-04  2.584002e-04  2.513404e-04  2.495531e-04
## [296]  2.467457e-04  2.450780e-04  2.418059e-04  2.388909e-04  2.355101e-04
## [301]  2.305684e-04  2.246771e-04  2.230079e-04  2.181439e-04  2.145263e-04
## [306]  2.102859e-04  2.088672e-04  2.035985e-04  2.005898e-04  1.980603e-04
## [311]  1.970223e-04  1.935723e-04  1.910534e-04  1.881783e-04  1.865563e-04
## [316]  1.840721e-04  1.825632e-04  1.782918e-04  1.715966e-04  1.693185e-04
## [321]  1.654891e-04  1.619246e-04  1.602732e-04  1.560122e-04  1.554147e-04
## [326]  1.542223e-04  1.492805e-04  1.460252e-04  1.451568e-04  1.419946e-04
## [331]  1.387771e-04  1.362864e-04  1.336528e-04  1.305837e-04  1.284662e-04
## [336]  1.267931e-04  1.216235e-04  1.201126e-04  1.176306e-04  1.145988e-04
## [341]  1.137066e-04  1.094717e-04  1.068799e-04  1.055413e-04  1.020175e-04
## [346]  9.862532e-05  9.546263e-05  9.519127e-05  9.318626e-05  9.036916e-05
## [351]  8.827579e-05  8.500779e-05  8.186932e-05  7.867424e-05  7.385582e-05
## [356]  7.299725e-05  7.221450e-05  7.172782e-05  6.968050e-05  6.644944e-05
## [361]  6.310574e-05  6.201264e-05  5.794394e-05  5.541145e-05  5.293600e-05
## [366]  5.248590e-05  4.978534e-05  4.922045e-05  4.566215e-05  4.198441e-05
## [371]  4.064646e-05  3.932131e-05  3.483786e-05  3.346301e-05  3.210071e-05
## [376]  2.906820e-05  2.741195e-05  2.432899e-05  2.378016e-05  2.010000e-05
## [381]  1.936500e-05  1.783159e-05  1.574245e-05  1.323577e-05  9.993666e-06
## [386]  8.851125e-06  7.563406e-06  3.479078e-06  2.481286e-06  4.282302e-09
## [391] -1.180320e-17 -2.015855e-06 -2.525260e-06 -5.554600e-06 -7.450615e-06
## [396] -8.706546e-06 -1.160099e-05 -1.284890e-05 -1.412788e-05 -1.788138e-05
## [401] -1.885677e-05 -2.109999e-05 -2.221902e-05 -2.478187e-05 -2.632699e-05
## [406] -2.792961e-05 -3.005512e-05 -3.122217e-05 -3.328885e-05 -3.503193e-05
## [411] -3.621992e-05 -3.854781e-05 -3.879774e-05 -4.246569e-05 -4.319644e-05
## [416] -4.438544e-05 -4.719214e-05 -4.816368e-05 -5.018774e-05 -5.153734e-05
## [421] -5.317054e-05 -5.582885e-05 -5.775549e-05 -5.989416e-05 -6.024394e-05
## [426] -6.253131e-05 -6.291809e-05 -6.336591e-05 -6.552028e-05 -6.660055e-05
## [431] -7.014513e-05 -7.193909e-05 -7.279550e-05 -7.479704e-05 -7.673899e-05
## [436] -7.839352e-05 -8.025797e-05 -8.071476e-05 -8.250077e-05 -8.344806e-05
## [441] -8.521283e-05 -8.592108e-05 -8.749341e-05 -9.024355e-05 -9.236850e-05
## [446] -9.255984e-05 -9.455588e-05 -9.609256e-05 -9.766571e-05 -9.980490e-05
## [451] -1.001706e-04 -1.024731e-04 -1.034966e-04 -1.049308e-04 -1.051075e-04
## [456] -1.071220e-04 -1.080921e-04 -1.119346e-04 -1.120918e-04 -1.129958e-04
## [461] -1.153818e-04 -1.161075e-04 -1.170423e-04 -1.199807e-04 -1.212392e-04
## [466] -1.217466e-04 -1.235848e-04 -1.251536e-04 -1.274108e-04 -1.282610e-04
## [471] -1.305982e-04 -1.319557e-04 -1.321589e-04 -1.338443e-04 -1.349502e-04
## [476] -1.373068e-04 -1.385090e-04 -1.396152e-04 -1.406933e-04 -1.420871e-04
## [481] -1.442467e-04 -1.452211e-04 -1.463608e-04 -1.481081e-04 -1.488831e-04
## [486] -1.498606e-04 -1.510412e-04 -1.534864e-04 -1.547065e-04 -1.561844e-04
## [491] -1.566496e-04 -1.579171e-04 -1.598014e-04 -1.609167e-04 -1.621341e-04
## [496] -1.644738e-04 -1.648690e-04 -1.660810e-04 -1.668519e-04 -1.673190e-04
## [501] -1.695127e-04 -1.705162e-04 -1.718717e-04 -1.738425e-04 -1.750860e-04
## [506] -1.751974e-04 -1.775590e-04 -1.797140e-04 -1.798585e-04 -1.807000e-04
## [511] -1.825200e-04 -1.835221e-04 -1.849161e-04 -1.858043e-04 -1.883165e-04
## [516] -1.887860e-04 -1.899570e-04 -1.905584e-04 -1.917556e-04 -1.926519e-04
## [521] -1.935726e-04 -1.952277e-04 -1.965221e-04 -1.978990e-04 -1.986121e-04
## [526] -1.998153e-04 -2.010566e-04 -2.016790e-04 -2.032230e-04 -2.039751e-04
## [531] -2.047831e-04 -2.064130e-04 -2.070436e-04 -2.090845e-04 -2.096981e-04
## [536] -2.106121e-04 -2.118002e-04 -2.131409e-04 -2.136080e-04 -2.153439e-04
## [541] -2.162197e-04 -2.164224e-04 -2.173343e-04 -2.190628e-04 -2.203490e-04
## [546] -2.213416e-04 -2.226128e-04 -2.233906e-04 -2.247410e-04 -2.259547e-04
## [551] -2.277140e-04 -2.282785e-04 -2.287998e-04 -2.300444e-04 -2.304389e-04
## [556] -2.316555e-04 -2.320253e-04 -2.342989e-04 -2.345067e-04 -2.372735e-04
## [561] -2.380312e-04 -2.383936e-04 -2.391992e-04 -2.398122e-04 -2.417644e-04
## [566] -2.422435e-04 -2.439036e-04 -2.457660e-04 -2.468578e-04 -2.486581e-04
## [571] -2.495979e-04 -2.503587e-04 -2.509628e-04 -2.518403e-04 -2.532092e-04
## [576] -2.545953e-04 -2.558910e-04 -2.562000e-04 -2.576982e-04 -2.581860e-04
## [581] -2.585379e-04 -2.589401e-04 -2.606667e-04 -2.620925e-04 -2.625657e-04
## [586] -2.640494e-04 -2.648346e-04 -2.649563e-04 -2.675655e-04 -2.680036e-04
## [591] -2.690030e-04 -2.696212e-04 -2.713626e-04 -2.719332e-04 -2.728183e-04
## [596] -2.742482e-04 -2.755556e-04 -2.766788e-04 -2.775586e-04 -2.789011e-04
## [601] -2.797638e-04 -2.802942e-04 -2.819644e-04 -2.830658e-04 -2.836966e-04
## [606] -2.843431e-04 -2.857876e-04 -2.864859e-04 -2.875144e-04 -2.895787e-04
## [611] -2.903568e-04 -2.910388e-04 -2.928195e-04 -2.936864e-04 -2.951713e-04
## [616] -2.964208e-04 -2.970228e-04 -2.977811e-04 -2.983087e-04 -2.995730e-04
## [621] -3.002020e-04 -3.015905e-04 -3.030248e-04 -3.035499e-04 -3.043197e-04
## [626] -3.048915e-04 -3.061885e-04 -3.078483e-04 -3.088835e-04 -3.100492e-04
## [631] -3.106489e-04 -3.117756e-04 -3.135847e-04 -3.142588e-04 -3.160641e-04
## [636] -3.161971e-04 -3.167419e-04 -3.180947e-04 -3.198833e-04 -3.203941e-04
## [641] -3.215505e-04 -3.234354e-04 -3.245050e-04 -3.257300e-04 -3.262286e-04
## [646] -3.265357e-04 -3.269867e-04 -3.288636e-04 -3.295438e-04 -3.307840e-04
## [651] -3.312231e-04 -3.334130e-04 -3.336881e-04 -3.354859e-04 -3.364534e-04
## [656] -3.376032e-04 -3.381226e-04 -3.393314e-04 -3.397803e-04 -3.423680e-04
## [661] -3.430532e-04 -3.436691e-04 -3.457665e-04 -3.468343e-04 -3.472168e-04
## [666] -3.488021e-04 -3.504957e-04 -3.507699e-04 -3.514421e-04 -3.525213e-04
## [671] -3.530361e-04 -3.540358e-04 -3.553147e-04 -3.565256e-04 -3.571949e-04
## [676] -3.594164e-04 -3.602136e-04 -3.613377e-04 -3.622590e-04 -3.631068e-04
## [681] -3.637673e-04 -3.648047e-04 -3.659927e-04 -3.680221e-04 -3.685856e-04
## [686] -3.702945e-04 -3.709698e-04 -3.715682e-04 -3.729854e-04 -3.738859e-04
## [691] -3.747637e-04 -3.764693e-04 -3.777114e-04 -3.798728e-04 -3.800790e-04
## [696] -3.811007e-04 -3.824027e-04 -3.841117e-04 -3.843849e-04 -3.868255e-04
## [701] -3.884663e-04 -3.891447e-04 -3.901191e-04 -3.903907e-04 -3.924556e-04
## [706] -3.932521e-04 -3.941333e-04 -3.960923e-04 -3.973182e-04 -3.977679e-04
## [711] -3.997213e-04 -4.003777e-04 -4.007234e-04 -4.020062e-04 -4.031223e-04
## [716] -4.046496e-04 -4.048511e-04 -4.077767e-04 -4.090415e-04 -4.096773e-04
## [721] -4.108751e-04 -4.115526e-04 -4.143660e-04 -4.153495e-04 -4.159402e-04
## [726] -4.165455e-04 -4.186816e-04 -4.202607e-04 -4.221928e-04 -4.238682e-04
## [731] -4.242866e-04 -4.255179e-04 -4.267996e-04 -4.278273e-04 -4.286225e-04
## [736] -4.301875e-04 -4.317052e-04 -4.331439e-04 -4.358240e-04 -4.366651e-04
## [741] -4.373844e-04 -4.384676e-04 -4.400621e-04 -4.407246e-04 -4.426483e-04
## [746] -4.443563e-04 -4.461260e-04 -4.463810e-04 -4.498770e-04 -4.511657e-04
## [751] -4.532904e-04 -4.539583e-04 -4.558467e-04 -4.571157e-04 -4.574177e-04
## [756] -4.605253e-04 -4.622483e-04 -4.629981e-04 -4.660730e-04 -4.672185e-04
## [761] -4.677744e-04 -4.697635e-04 -4.721022e-04 -4.734384e-04 -4.737742e-04
## [766] -4.770219e-04 -4.780271e-04 -4.791729e-04 -4.816580e-04 -4.825813e-04
## [771] -4.858186e-04 -4.865880e-04 -4.887858e-04 -4.900582e-04 -4.904163e-04
## [776] -4.933199e-04 -4.953480e-04 -4.968444e-04 -4.985764e-04 -5.016257e-04
## [781] -5.028302e-04 -5.040875e-04 -5.067812e-04 -5.088462e-04 -5.120755e-04
## [786] -5.134970e-04 -5.164242e-04 -5.167821e-04 -5.216200e-04 -5.240918e-04
## [791] -5.270672e-04 -5.291110e-04 -5.314020e-04 -5.319564e-04 -5.350352e-04
## [796] -5.374980e-04 -5.420553e-04 -5.442999e-04 -5.457422e-04 -5.467807e-04
## [801] -5.545382e-04 -5.566680e-04 -5.597679e-04 -5.634053e-04 -5.658447e-04
## [806] -5.691666e-04 -5.711935e-04 -5.755561e-04 -5.772588e-04 -5.816699e-04
## [811] -5.844372e-04 -5.874054e-04 -5.944582e-04 -5.995390e-04 -6.019137e-04
## [816] -6.075004e-04 -6.118578e-04 -6.148555e-04 -6.188718e-04 -6.207718e-04
## [821] -6.286224e-04 -6.349958e-04 -6.439527e-04 -6.481871e-04 -6.496957e-04
## [826] -6.584480e-04 -6.634306e-04 -6.690999e-04 -6.745818e-04 -6.810222e-04
## [831] -7.052150e-04 -7.116382e-04 -7.255332e-04 -7.294360e-04 -7.360548e-04
## [836] -7.400887e-04 -7.505075e-04 -7.850255e-04 -7.892063e-04 -8.133337e-04
## [841] -8.338068e-04 -8.366386e-04 -8.516154e-04 -8.785681e-04 -8.920825e-04
## [846] -9.117977e-04 -9.736868e-04 -1.030370e-03 -1.128196e-03 -1.421792e-03
## [851] -2.250524e-03
evaluate_consistency_metrics(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
## $trustworthiness
## [1] 0.601961
## 
## $continuity
## [1] 0.845357
## 
## $mantel_statistic
## [1] 0.3053222
## 
## $mantel_p
## [1] 0.001
cjtt_u_test(dist_bray_filt, CRP_filt, var_method = "analytic")
## $U_statistic
## [1] 0.04386258
## 
## $variance
## [1] 0.000521647
## 
## $z_score
## [1] 1.920463
## 
## $p_value
## [1] 0.05479949
## 
## $method
## [1] "analytic"
gco_decomposition(pcoa_mat = res$PCoA_coordinates,projection_scores = res$projection_scores)
##     consistency_score outlier        class
## 1                 0.0   FALSE       C-type
## 2                 0.0   FALSE       C-type
## 3                 0.0   FALSE       C-type
## 4                 0.0   FALSE       C-type
## 5                 0.0   FALSE       C-type
## 6                 0.0   FALSE       C-type
## 7                 0.0   FALSE       C-type
## 8                 0.1   FALSE       C-type
## 9                 0.0   FALSE       C-type
## 10                0.0   FALSE       C-type
## 11                0.0   FALSE       C-type
## 12                0.0   FALSE       C-type
## 13                0.1   FALSE       C-type
## 14                0.1   FALSE       C-type
## 15                0.2   FALSE Intermediate
## 16                0.1   FALSE       C-type
## 17                0.1   FALSE       C-type
## 18                0.0   FALSE       C-type
## 19                0.0   FALSE       C-type
## 20                0.1   FALSE       C-type
## 21                0.1   FALSE       C-type
## 22                0.0   FALSE       C-type
## 23                0.3    TRUE       O-type
## 24                0.0   FALSE       C-type
## 25                0.0   FALSE       C-type
## 26                0.2    TRUE       O-type
## 27                0.1   FALSE       C-type
## 28                0.1   FALSE       C-type
## 29                0.0   FALSE       C-type
## 30                0.1   FALSE       C-type
## 31                0.0   FALSE       C-type
## 32                0.0   FALSE       C-type
## 33                0.0   FALSE       C-type
## 34                0.0   FALSE       C-type
## 35                0.0   FALSE       C-type
## 36                0.1   FALSE       C-type
## 37                0.0   FALSE       C-type
## 38                0.1    TRUE       O-type
## 39                0.0   FALSE       C-type
## 40                0.0   FALSE       C-type
## 41                0.0   FALSE       C-type
## 42                0.3   FALSE Intermediate
## 43                0.1   FALSE       C-type
## 44                0.0   FALSE       C-type
## 45                0.1   FALSE       C-type
## 46                0.1   FALSE       C-type
## 47                0.0   FALSE       C-type
## 48                0.0   FALSE       C-type
## 49                0.0   FALSE       C-type
## 50                0.2   FALSE Intermediate
## 51                0.0   FALSE       C-type
## 52                0.1   FALSE       C-type
## 53                0.1   FALSE       C-type
## 54                0.1   FALSE       C-type
## 55                0.0    TRUE       O-type
## 56                0.0   FALSE       C-type
## 57                0.1   FALSE       C-type
## 58                0.2   FALSE Intermediate
## 59                0.0   FALSE       C-type
## 60                0.1   FALSE       C-type
## 61                0.1   FALSE       C-type
## 62                0.1   FALSE       C-type
## 63                0.1   FALSE       C-type
## 64                0.1   FALSE       C-type
## 65                0.0   FALSE       C-type
## 66                0.3   FALSE Intermediate
## 67                0.0   FALSE       C-type
## 68                0.1   FALSE       C-type
## 69                0.1   FALSE       C-type
## 70                0.0   FALSE       C-type
## 71                0.0   FALSE       C-type
## 72                0.0   FALSE       C-type
## 73                0.0   FALSE       C-type
## 74                0.2   FALSE Intermediate
## 75                0.0   FALSE       C-type
## 76                0.0   FALSE       C-type
## 77                0.1   FALSE       C-type
## 78                0.2   FALSE Intermediate
## 79                0.0    TRUE       O-type
## 80                0.1   FALSE       C-type
## 81                0.1   FALSE       C-type
## 82                0.1   FALSE       C-type
## 83                0.1   FALSE       C-type
## 84                0.0   FALSE       C-type
## 85                0.0   FALSE       C-type
## 86                0.1    TRUE       O-type
## 87                0.0   FALSE       C-type
## 88                0.1   FALSE       C-type
## 89                0.1   FALSE       C-type
## 90                0.1   FALSE       C-type
## 91                0.0    TRUE       O-type
## 92                0.0   FALSE       C-type
## 93                0.1   FALSE       C-type
## 94                0.0   FALSE       C-type
## 95                0.0   FALSE       C-type
## 96                0.0   FALSE       C-type
## 97                0.1   FALSE       C-type
## 98                0.0   FALSE       C-type
## 99                0.0   FALSE       C-type
## 100               0.1   FALSE       C-type
## 101               0.0   FALSE       C-type
## 102               0.1   FALSE       C-type
## 103               0.0   FALSE       C-type
## 104               0.1   FALSE       C-type
## 105               0.2   FALSE Intermediate
## 106               0.0   FALSE       C-type
## 107               0.2   FALSE Intermediate
## 108               0.2   FALSE Intermediate
## 109               0.1   FALSE       C-type
## 110               0.1   FALSE       C-type
## 111               0.0   FALSE       C-type
## 112               0.0   FALSE       C-type
## 113               0.0   FALSE       C-type
## 114               0.0   FALSE       C-type
## 115               0.0   FALSE       C-type
## 116               0.1    TRUE       O-type
## 117               0.1   FALSE       C-type
## 118               0.0   FALSE       C-type
## 119               0.0   FALSE       C-type
## 120               0.1   FALSE       C-type
## 121               0.0   FALSE       C-type
## 122               0.1   FALSE       C-type
## 123               0.0   FALSE       C-type
## 124               0.0   FALSE       C-type
## 125               0.1    TRUE       O-type
## 126               0.0   FALSE       C-type
## 127               0.1   FALSE       C-type
## 128               0.1   FALSE       C-type
## 129               0.1   FALSE       C-type
## 130               0.0   FALSE       C-type
## 131               0.1    TRUE       O-type
## 132               0.3   FALSE Intermediate
## 133               0.1   FALSE       C-type
## 134               0.0   FALSE       C-type
## 135               0.0   FALSE       C-type
## 136               0.0   FALSE       C-type
## 137               0.0   FALSE       C-type
## 138               0.0   FALSE       C-type
## 139               0.1   FALSE       C-type
## 140               0.2   FALSE Intermediate
## 141               0.0   FALSE       C-type
## 142               0.0   FALSE       C-type
## 143               0.1   FALSE       C-type
## 144               0.0   FALSE       C-type
## 145               0.1   FALSE       C-type
## 146               0.0   FALSE       C-type
## 147               0.1   FALSE       C-type
## 148               0.2   FALSE Intermediate
## 149               0.0   FALSE       C-type
## 150               0.1   FALSE       C-type
## 151               0.0   FALSE       C-type
## 152               0.0   FALSE       C-type
## 153               0.0   FALSE       C-type
## 154               0.0   FALSE       C-type
## 155               0.2   FALSE Intermediate
## 156               0.2    TRUE       O-type
## 157               0.0   FALSE       C-type
## 158               0.0   FALSE       C-type
## 159               0.0   FALSE       C-type
## 160               0.0   FALSE       C-type
## 161               0.1   FALSE       C-type
## 162               0.0   FALSE       C-type
## 163               0.1   FALSE       C-type
## 164               0.1   FALSE       C-type
## 165               0.1   FALSE       C-type
## 166               0.0   FALSE       C-type
## 167               0.0   FALSE       C-type
## 168               0.0   FALSE       C-type
## 169               0.0   FALSE       C-type
## 170               0.0   FALSE       C-type
## 171               0.1   FALSE       C-type
## 172               0.0   FALSE       C-type
## 173               0.1   FALSE       C-type
## 174               0.0   FALSE       C-type
## 175               0.1   FALSE       C-type
## 176               0.0   FALSE       C-type
## 177               0.0   FALSE       C-type
## 178               0.2    TRUE       O-type
## 179               0.2   FALSE Intermediate
## 180               0.0   FALSE       C-type
## 181               0.0   FALSE       C-type
## 182               0.1   FALSE       C-type
## 183               0.2   FALSE Intermediate
## 184               0.0   FALSE       C-type
## 185               0.0   FALSE       C-type
## 186               0.0   FALSE       C-type
## 187               0.1   FALSE       C-type
## 188               0.1   FALSE       C-type
## 189               0.1   FALSE       C-type
## 190               0.5    TRUE       O-type
## 191               0.0   FALSE       C-type
## 192               0.0   FALSE       C-type
## 193               0.0   FALSE       C-type
## 194               0.0   FALSE       C-type
## 195               0.1   FALSE       C-type
## 196               0.0   FALSE       C-type
## 197               0.0   FALSE       C-type
## 198               0.1   FALSE       C-type
## 199               0.0   FALSE       C-type
## 200               0.0   FALSE       C-type
## 201               0.1   FALSE       C-type
## 202               0.1   FALSE       C-type
## 203               0.0   FALSE       C-type
## 204               0.2   FALSE Intermediate
## 205               0.1   FALSE       C-type
## 206               0.0   FALSE       C-type
## 207               0.0    TRUE       O-type
## 208               0.0   FALSE       C-type
## 209               0.1   FALSE       C-type
## 210               0.1   FALSE       C-type
## 211               0.2    TRUE       O-type
## 212               0.0   FALSE       C-type
## 213               0.0   FALSE       C-type
## 214               0.0   FALSE       C-type
## 215               0.0   FALSE       C-type
## 216               0.0   FALSE       C-type
## 217               0.0   FALSE       C-type
## 218               0.0   FALSE       C-type
## 219               0.0   FALSE       C-type
## 220               0.2   FALSE Intermediate
## 221               0.0   FALSE       C-type
## 222               0.1   FALSE       C-type
## 223               0.1    TRUE       O-type
## 224               0.0   FALSE       C-type
## 225               0.0    TRUE       O-type
## 226               0.1   FALSE       C-type
## 227               0.0   FALSE       C-type
## 228               0.1   FALSE       C-type
## 229               0.0   FALSE       C-type
## 230               0.0   FALSE       C-type
## 231               0.1   FALSE       C-type
## 232               0.0   FALSE       C-type
## 233               0.1   FALSE       C-type
## 234               0.0   FALSE       C-type
## 235               0.0   FALSE       C-type
## 236               0.1   FALSE       C-type
## 237               0.1   FALSE       C-type
## 238               0.0   FALSE       C-type
## 239               0.1   FALSE       C-type
## 240               0.1   FALSE       C-type
## 241               0.0   FALSE       C-type
## 242               0.2   FALSE Intermediate
## 243               0.1   FALSE       C-type
## 244               0.4    TRUE       O-type
## 245               0.1   FALSE       C-type
## 246               0.1   FALSE       C-type
## 247               0.0   FALSE       C-type
## 248               0.0   FALSE       C-type
## 249               0.0   FALSE       C-type
## 250               0.0   FALSE       C-type
## 251               0.1   FALSE       C-type
## 252               0.1   FALSE       C-type
## 253               0.2   FALSE Intermediate
## 254               0.1   FALSE       C-type
## 255               0.0   FALSE       C-type
## 256               0.0   FALSE       C-type
## 257               0.0   FALSE       C-type
## 258               0.3   FALSE Intermediate
## 259               0.1   FALSE       C-type
## 260               0.3   FALSE Intermediate
## 261               0.0   FALSE       C-type
## 262               0.0   FALSE       C-type
## 263               0.1   FALSE       C-type
## 264               0.1   FALSE       C-type
## 265               0.0   FALSE       C-type
## 266               0.0   FALSE       C-type
## 267               0.1   FALSE       C-type
## 268               0.0   FALSE       C-type
## 269               0.1   FALSE       C-type
## 270               0.1   FALSE       C-type
## 271               0.0   FALSE       C-type
## 272               0.0   FALSE       C-type
## 273               0.0   FALSE       C-type
## 274               0.0    TRUE       O-type
## 275               0.0   FALSE       C-type
## 276               0.0   FALSE       C-type
## 277               0.1   FALSE       C-type
## 278               0.0   FALSE       C-type
## 279               0.2    TRUE       O-type
## 280               0.0   FALSE       C-type
## 281               0.0   FALSE       C-type
## 282               0.0   FALSE       C-type
## 283               0.0   FALSE       C-type
## 284               0.2   FALSE Intermediate
## 285               0.4   FALSE Intermediate
## 286               0.1   FALSE       C-type
## 287               0.0   FALSE       C-type
## 288               0.0   FALSE       C-type
## 289               0.1   FALSE       C-type
## 290               0.1   FALSE       C-type
## 291               0.0   FALSE       C-type
## 292               0.0   FALSE       C-type
## 293               0.1   FALSE       C-type
## 294               0.1   FALSE       C-type
## 295               0.1   FALSE       C-type
## 296               0.0   FALSE       C-type
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## 298               0.0   FALSE       C-type
## 299               0.1   FALSE       C-type
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## 301               0.0   FALSE       C-type
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## 303               0.0   FALSE       C-type
## 304               0.0   FALSE       C-type
## 305               0.1   FALSE       C-type
## 306               0.0   FALSE       C-type
## 307               0.3   FALSE Intermediate
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## 309               0.0   FALSE       C-type
## 310               0.1   FALSE       C-type
## 311               0.0   FALSE       C-type
## 312               0.2   FALSE Intermediate
## 313               0.1   FALSE       C-type
## 314               0.1   FALSE       C-type
## 315               0.1   FALSE       C-type
## 316               0.0   FALSE       C-type
## 317               0.1   FALSE       C-type
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## 321               0.0   FALSE       C-type
## 322               0.0   FALSE       C-type
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## 324               0.1   FALSE       C-type
## 325               0.0   FALSE       C-type
## 326               0.0   FALSE       C-type
## 327               0.2   FALSE Intermediate
## 328               0.0   FALSE       C-type
## 329               0.0   FALSE       C-type
## 330               0.2   FALSE Intermediate
## 331               0.0   FALSE       C-type
## 332               0.0   FALSE       C-type
## 333               0.0   FALSE       C-type
## 334               0.1   FALSE       C-type
## 335               0.0   FALSE       C-type
## 336               0.2   FALSE Intermediate
## 337               0.0   FALSE       C-type
## 338               0.0   FALSE       C-type
## 339               0.0   FALSE       C-type
## 340               0.2   FALSE Intermediate
## 341               0.0   FALSE       C-type
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## 343               0.1   FALSE       C-type
## 344               0.0   FALSE       C-type
## 345               0.0   FALSE       C-type
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## 348               0.0   FALSE       C-type
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## 352               0.0   FALSE       C-type
## 353               0.1   FALSE       C-type
## 354               0.0   FALSE       C-type
## 355               0.0   FALSE       C-type
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## 357               0.0   FALSE       C-type
## 358               0.0   FALSE       C-type
## 359               0.0   FALSE       C-type
## 360               0.0    TRUE       O-type
## 361               0.1    TRUE       O-type
## 362               0.0   FALSE       C-type
## 363               0.1   FALSE       C-type
## 364               0.2   FALSE Intermediate
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## 366               0.1   FALSE       C-type
## 367               0.2    TRUE       O-type
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## 369               0.1   FALSE       C-type
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## 373               0.1   FALSE       C-type
## 374               0.1   FALSE       C-type
## 375               0.0   FALSE       C-type
## 376               0.2   FALSE Intermediate
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## 378               0.0   FALSE       C-type
## 379               0.0   FALSE       C-type
## 380               0.1   FALSE       C-type
## 381               0.0   FALSE       C-type
## 382               0.0   FALSE       C-type
## 383               0.1   FALSE       C-type
## 384               0.1   FALSE       C-type
## 385               0.0    TRUE       O-type
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## 387               0.0    TRUE       O-type
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## 389               0.0   FALSE       C-type
## 390               0.1   FALSE       C-type
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## 392               0.1   FALSE       C-type
## 393               0.0   FALSE       C-type
## 394               0.1   FALSE       C-type
## 395               0.2   FALSE Intermediate
## 396               0.1   FALSE       C-type
## 397               0.1   FALSE       C-type
## 398               0.2   FALSE Intermediate
## 399               0.1   FALSE       C-type
## 400               0.0   FALSE       C-type
## 401               0.0   FALSE       C-type
## 402               0.0   FALSE       C-type
## 403               0.0   FALSE       C-type
## 404               0.1   FALSE       C-type
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## 406               0.0   FALSE       C-type
## 407               0.1   FALSE       C-type
## 408               0.0   FALSE       C-type
## 409               0.0   FALSE       C-type
## 410               0.4    TRUE       O-type
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## 414               0.0   FALSE       C-type
## 415               0.0   FALSE       C-type
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## 417               0.0   FALSE       C-type
## 418               0.0   FALSE       C-type
## 419               0.1   FALSE       C-type
## 420               0.1   FALSE       C-type
## 421               0.2   FALSE Intermediate
## 422               0.1   FALSE       C-type
## 423               0.0   FALSE       C-type
## 424               0.1   FALSE       C-type
## 425               0.4    TRUE       O-type
## 426               0.0   FALSE       C-type
## 427               0.1   FALSE       C-type
## 428               0.0   FALSE       C-type
## 429               0.0   FALSE       C-type
## 430               0.1   FALSE       C-type
## 431               0.0   FALSE       C-type
## 432               0.0   FALSE       C-type
## 433               0.0    TRUE       O-type
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## 435               0.0   FALSE       C-type
## 436               0.0   FALSE       C-type
## 437               0.1   FALSE       C-type
## 438               0.2   FALSE Intermediate
## 439               0.0   FALSE       C-type
## 440               0.1   FALSE       C-type
## 441               0.1   FALSE       C-type
## 442               0.0   FALSE       C-type
## 443               0.1   FALSE       C-type
## 444               0.0   FALSE       C-type
## 445               0.0    TRUE       O-type
## 446               0.0   FALSE       C-type
## 447               0.0   FALSE       C-type
## 448               0.1   FALSE       C-type
## 449               0.1   FALSE       C-type
## 450               0.0   FALSE       C-type
## 451               0.1   FALSE       C-type
## 452               0.1   FALSE       C-type
## 453               0.0   FALSE       C-type
## 454               0.2   FALSE Intermediate
## 455               0.2    TRUE       O-type
## 456               0.0   FALSE       C-type
## 457               0.1   FALSE       C-type
## 458               0.0   FALSE       C-type
## 459               0.0   FALSE       C-type
## 460               0.5    TRUE       O-type
## 461               0.0   FALSE       C-type
## 462               0.0   FALSE       C-type
## 463               0.0   FALSE       C-type
## 464               0.1   FALSE       C-type
## 465               0.1   FALSE       C-type
## 466               0.0   FALSE       C-type
## 467               0.1    TRUE       O-type
## 468               0.0   FALSE       C-type
## 469               0.0   FALSE       C-type
## 470               0.1   FALSE       C-type
## 471               0.3    TRUE       O-type
## 472               0.2   FALSE Intermediate
## 473               0.0    TRUE       O-type
## 474               0.0   FALSE       C-type
## 475               0.0   FALSE       C-type
## 476               0.0   FALSE       C-type
## 477               0.0   FALSE       C-type
## 478               0.0    TRUE       O-type
## 479               0.1   FALSE       C-type
## 480               0.0   FALSE       C-type
## 481               0.0   FALSE       C-type
## 482               0.1   FALSE       C-type
## 483               0.1   FALSE       C-type
## 484               0.1   FALSE       C-type
## 485               0.0   FALSE       C-type
## 486               0.1   FALSE       C-type
## 487               0.3    TRUE       O-type
## 488               0.0   FALSE       C-type
## 489               0.2   FALSE Intermediate
## 490               0.0   FALSE       C-type
## 491               0.1   FALSE       C-type
## 492               0.0   FALSE       C-type
## 493               0.1   FALSE       C-type
## 494               0.0   FALSE       C-type
## 495               0.0    TRUE       O-type
## 496               0.0   FALSE       C-type
## 497               0.0   FALSE       C-type
## 498               0.2   FALSE Intermediate
## 499               0.0    TRUE       O-type
## 500               0.1    TRUE       O-type
## 501               0.1    TRUE       O-type
## 502               0.1   FALSE       C-type
## 503               0.0   FALSE       C-type
## 504               0.1   FALSE       C-type
## 505               0.0   FALSE       C-type
## 506               0.3    TRUE       O-type
## 507               0.0   FALSE       C-type
## 508               0.0   FALSE       C-type
## 509               0.1    TRUE       O-type
## 510               0.0   FALSE       C-type
## 511               0.0   FALSE       C-type
## 512               0.2   FALSE Intermediate
## 513               0.0   FALSE       C-type
## 514               0.0   FALSE       C-type
## 515               0.0   FALSE       C-type
## 516               0.0   FALSE       C-type
## 517               0.0   FALSE       C-type
## 518               0.0   FALSE       C-type
## 519               0.1   FALSE       C-type
## 520               0.0   FALSE       C-type
## 521               0.0   FALSE       C-type
## 522               0.2   FALSE Intermediate
## 523               0.0    TRUE       O-type
## 524               0.0   FALSE       C-type
## 525               0.0   FALSE       C-type
## 526               0.3    TRUE       O-type
## 527               0.0   FALSE       C-type
## 528               0.1   FALSE       C-type
## 529               0.0   FALSE       C-type
## 530               0.0   FALSE       C-type
## 531               0.0   FALSE       C-type
## 532               0.0   FALSE       C-type
## 533               0.0    TRUE       O-type
## 534               0.1   FALSE       C-type
## 535               0.1   FALSE       C-type
## 536               0.0    TRUE       O-type
## 537               0.0   FALSE       C-type
## 538               0.0   FALSE       C-type
## 539               0.0   FALSE       C-type
## 540               0.0   FALSE       C-type
## 541               0.1   FALSE       C-type
## 542               0.1   FALSE       C-type
## 543               0.1   FALSE       C-type
## 544               0.0   FALSE       C-type
## 545               0.1   FALSE       C-type
## 546               0.0   FALSE       C-type
## 547               0.0   FALSE       C-type
## 548               0.1   FALSE       C-type
## 549               0.0   FALSE       C-type
## 550               0.0    TRUE       O-type
## 551               0.0   FALSE       C-type
## 552               0.1   FALSE       C-type
## 553               0.0    TRUE       O-type
## 554               0.0   FALSE       C-type
## 555               0.1    TRUE       O-type
## 556               0.1   FALSE       C-type
## 557               0.3    TRUE       O-type
## 558               0.0   FALSE       C-type
## 559               0.0   FALSE       C-type
## 560               0.0   FALSE       C-type
## 561               0.0    TRUE       O-type
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## 563               0.0   FALSE       C-type
## 564               0.0   FALSE       C-type
## 565               0.0   FALSE       C-type
## 566               0.0   FALSE       C-type
## 567               0.0   FALSE       C-type
## 568               0.0   FALSE       C-type
## 569               0.0   FALSE       C-type
## 570               0.0   FALSE       C-type
## 571               0.0   FALSE       C-type
## 572               0.0    TRUE       O-type
## 573               0.0   FALSE       C-type
## 574               0.0   FALSE       C-type
## 575               0.1   FALSE       C-type
## 576               0.0   FALSE       C-type
## 577               0.0   FALSE       C-type
## 578               0.0   FALSE       C-type
## 579               0.1   FALSE       C-type
## 580               0.0   FALSE       C-type
## 581               0.2   FALSE Intermediate
## 582               0.0   FALSE       C-type
## 583               0.3    TRUE       O-type
## 584               0.2   FALSE Intermediate
## 585               0.1    TRUE       O-type
## 586               0.1    TRUE       O-type
## 587               0.0   FALSE       C-type
## 588               0.0    TRUE       O-type
## 589               0.2   FALSE Intermediate
## 590               0.0   FALSE       C-type
## 591               0.1    TRUE       O-type
## 592               0.0   FALSE       C-type
## 593               0.0   FALSE       C-type
## 594               0.2   FALSE Intermediate
## 595               0.0   FALSE       C-type
## 596               0.1   FALSE       C-type
## 597               0.0   FALSE       C-type
## 598               0.0   FALSE       C-type
## 599               0.0   FALSE       C-type
## 600               0.0   FALSE       C-type
## 601               0.1   FALSE       C-type
## 602               0.1    TRUE       O-type
## 603               0.0   FALSE       C-type
## 604               0.1   FALSE       C-type
## 605               0.1   FALSE       C-type
## 606               0.1   FALSE       C-type
## 607               0.0   FALSE       C-type
## 608               0.1   FALSE       C-type
## 609               0.1    TRUE       O-type
## 610               0.1   FALSE       C-type
## 611               0.0   FALSE       C-type
## 612               0.0    TRUE       O-type
## 613               0.0   FALSE       C-type
## 614               0.0   FALSE       C-type
## 615               0.0   FALSE       C-type
## 616               0.0   FALSE       C-type
## 617               0.2   FALSE Intermediate
## 618               0.0   FALSE       C-type
## 619               0.1   FALSE       C-type
## 620               0.2   FALSE Intermediate
## 621               0.0   FALSE       C-type
## 622               0.0   FALSE       C-type
## 623               0.1   FALSE       C-type
## 624               0.1   FALSE       C-type
## 625               0.2   FALSE Intermediate
## 626               0.0   FALSE       C-type
## 627               0.0   FALSE       C-type
## 628               0.1   FALSE       C-type
## 629               0.0   FALSE       C-type
## 630               0.0   FALSE       C-type
## 631               0.0   FALSE       C-type
## 632               0.0   FALSE       C-type
## 633               0.0   FALSE       C-type
## 634               0.0   FALSE       C-type
## 635               0.4    TRUE       O-type
## 636               0.2   FALSE Intermediate
## 637               0.1   FALSE       C-type
## 638               0.1   FALSE       C-type
## 639               0.0   FALSE       C-type
## 640               0.0   FALSE       C-type
## 641               0.0   FALSE       C-type
## 642               0.1   FALSE       C-type
## 643               0.0   FALSE       C-type
## 644               0.0   FALSE       C-type
## 645               0.0   FALSE       C-type
## 646               0.2   FALSE Intermediate
## 647               0.0   FALSE       C-type
## 648               0.0   FALSE       C-type
## 649               0.0   FALSE       C-type
## 650               0.0   FALSE       C-type
## 651               0.1   FALSE       C-type
## 652               0.0    TRUE       O-type
## 653               0.0   FALSE       C-type
## 654               0.0   FALSE       C-type
## 655               0.0   FALSE       C-type
## 656               0.0   FALSE       C-type
## 657               0.0   FALSE       C-type
## 658               0.0   FALSE       C-type
## 659               0.0   FALSE       C-type
## 660               0.0    TRUE       O-type
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## 662               0.0   FALSE       C-type
## 663               0.0   FALSE       C-type
## 664               0.0   FALSE       C-type
## 665               0.0   FALSE       C-type
## 666               0.1   FALSE       C-type
## 667               0.1   FALSE       C-type
## 668               0.0   FALSE       C-type
## 669               0.0   FALSE       C-type
## 670               0.0   FALSE       C-type
## 671               0.2   FALSE Intermediate
## 672               0.0   FALSE       C-type
## 673               0.0   FALSE       C-type
## 674               0.1   FALSE       C-type
## 675               0.0   FALSE       C-type
## 676               0.0   FALSE       C-type
## 677               0.0   FALSE       C-type
## 678               0.0   FALSE       C-type
## 679               0.0   FALSE       C-type
## 680               0.1   FALSE       C-type
## 681               0.0   FALSE       C-type
## 682               0.0   FALSE       C-type
## 683               0.1   FALSE       C-type
## 684               0.0   FALSE       C-type
## 685               0.0   FALSE       C-type
## 686               0.0   FALSE       C-type
## 687               0.0   FALSE       C-type
## 688               0.1   FALSE       C-type
## 689               0.0   FALSE       C-type
## 690               0.1   FALSE       C-type
## 691               0.1   FALSE       C-type
## 692               0.2   FALSE Intermediate
## 693               0.1   FALSE       C-type
## 694               0.0   FALSE       C-type
## 695               0.2   FALSE Intermediate
## 696               0.0   FALSE       C-type
## 697               0.0   FALSE       C-type
## 698               0.0   FALSE       C-type
## 699               0.1   FALSE       C-type
## 700               0.0   FALSE       C-type
## 701               0.0   FALSE       C-type
## 702               0.0   FALSE       C-type
## 703               0.1   FALSE       C-type
## 704               0.1   FALSE       C-type
## 705               0.0   FALSE       C-type
## 706               0.0   FALSE       C-type
## 707               0.0   FALSE       C-type
## 708               0.0   FALSE       C-type
## 709               0.0   FALSE       C-type
## 710               0.1    TRUE       O-type
## 711               0.0   FALSE       C-type
## 712               0.1   FALSE       C-type
## 713               0.0   FALSE       C-type
## 714               0.0   FALSE       C-type
## 715               0.0   FALSE       C-type
## 716               0.0   FALSE       C-type
## 717               0.3    TRUE       O-type
## 718               0.1   FALSE       C-type
## 719               0.1   FALSE       C-type
## 720               0.0   FALSE       C-type
## 721               0.0   FALSE       C-type
## 722               0.0   FALSE       C-type
## 723               0.0   FALSE       C-type
## 724               0.1   FALSE       C-type
## 725               0.1   FALSE       C-type
## 726               0.0   FALSE       C-type
## 727               0.0   FALSE       C-type
## 728               0.1   FALSE       C-type
## 729               0.1   FALSE       C-type
## 730               0.0   FALSE       C-type
## 731               0.1   FALSE       C-type
## 732               0.2   FALSE Intermediate
## 733               0.0   FALSE       C-type
## 734               0.0   FALSE       C-type
## 735               0.0   FALSE       C-type
## 736               0.0   FALSE       C-type
## 737               0.0   FALSE       C-type
## 738               0.0   FALSE       C-type
## 739               0.0   FALSE       C-type
## 740               0.0    TRUE       O-type
## 741               0.0    TRUE       O-type
## 742               0.0   FALSE       C-type
## 743               0.0   FALSE       C-type
## 744               0.0   FALSE       C-type
## 745               0.0   FALSE       C-type
## 746               0.0   FALSE       C-type
## 747               0.0   FALSE       C-type
## 748               0.1   FALSE       C-type
## 749               0.1   FALSE       C-type
## 750               0.1   FALSE       C-type
## 751               0.1   FALSE       C-type
## 752               0.0   FALSE       C-type
## 753               0.0   FALSE       C-type
## 754               0.0   FALSE       C-type
## 755               0.0   FALSE       C-type
## 756               0.1   FALSE       C-type
## 757               0.0   FALSE       C-type
## 758               0.1   FALSE       C-type
## 759               0.0   FALSE       C-type
## 760               0.0   FALSE       C-type
## 761               0.0   FALSE       C-type
## 762               0.0   FALSE       C-type
## 763               0.0   FALSE       C-type
## 764               0.0   FALSE       C-type
## 765               0.0   FALSE       C-type
## 766               0.0   FALSE       C-type
## 767               0.0   FALSE       C-type
## 768               0.0   FALSE       C-type
## 769               0.0    TRUE       O-type
## 770               0.1   FALSE       C-type
## 771               0.0   FALSE       C-type
## 772               0.0    TRUE       O-type
## 773               0.1   FALSE       C-type
## 774               0.0   FALSE       C-type
## 775               0.0   FALSE       C-type
## 776               0.0    TRUE       O-type
## 777               0.0   FALSE       C-type
## 778               0.0   FALSE       C-type
## 779               0.0   FALSE       C-type
## 780               0.0   FALSE       C-type
## 781               0.2   FALSE Intermediate
## 782               0.0   FALSE       C-type
## 783               0.0   FALSE       C-type
## 784               0.0   FALSE       C-type
## 785               0.1   FALSE       C-type
## 786               0.0    TRUE       O-type
## 787               0.0    TRUE       O-type
## 788               0.1   FALSE       C-type
## 789               0.0   FALSE       C-type
## 790               0.1   FALSE       C-type
## 791               0.0   FALSE       C-type
## 792               0.0   FALSE       C-type
## 793               0.0   FALSE       C-type
## 794               0.0   FALSE       C-type
## 795               0.1   FALSE       C-type
## 796               0.0   FALSE       C-type
## 797               0.0   FALSE       C-type
## 798               0.0   FALSE       C-type
## 799               0.0   FALSE       C-type
## 800               0.1    TRUE       O-type
## 801               0.0   FALSE       C-type
## 802               0.0   FALSE       C-type
## 803               0.0   FALSE       C-type
## 804               0.0   FALSE       C-type
## 805               0.0   FALSE       C-type
## 806               0.1   FALSE       C-type
## 807               0.0   FALSE       C-type
## 808               0.0    TRUE       O-type
## 809               0.0   FALSE       C-type
## 810               0.1   FALSE       C-type
## 811               0.2   FALSE Intermediate
## 812               0.0   FALSE       C-type
## 813               0.0   FALSE       C-type
## 814               0.0   FALSE       C-type
## 815               0.1   FALSE       C-type
## 816               0.1   FALSE       C-type
## 817               0.0   FALSE       C-type
## 818               0.1   FALSE       C-type
## 819               0.0   FALSE       C-type
## 820               0.0   FALSE       C-type
## 821               0.0    TRUE       O-type
## 822               0.2   FALSE Intermediate
## 823               0.0   FALSE       C-type
## 824               0.0   FALSE       C-type
## 825               0.0   FALSE       C-type
## 826               0.0   FALSE       C-type
## 827               0.1   FALSE       C-type
## 828               0.1   FALSE       C-type
## 829               0.2   FALSE Intermediate
## 830               0.1    TRUE       O-type
## 831               0.1   FALSE       C-type
## 832               0.1   FALSE       C-type
## 833               0.1   FALSE       C-type
## 834               0.1   FALSE       C-type
## 835               0.1   FALSE       C-type
## 836               0.2   FALSE Intermediate
## 837               0.1   FALSE       C-type
## 838               0.0   FALSE       C-type
## 839               0.1   FALSE       C-type
## 840               0.1   FALSE       C-type
## 841               0.0   FALSE       C-type
## 842               0.0   FALSE       C-type
## 843               0.0   FALSE       C-type
## 844               0.0   FALSE       C-type
## 845               0.0   FALSE       C-type
## 846               0.0    TRUE       O-type
## 847               0.0   FALSE       C-type
## 848               0.1   FALSE       C-type
## 849               0.0   FALSE       C-type
## 850               0.2    TRUE       O-type
## 851               0.2    TRUE       O-type